Possible dosage regimens for topical steroids assessed by vasoconstrictor assays using multiple applications

Title: Possible dosage regimens for topical steroids assessed by vasoconstrictor assays using multiple applications
Creator: Woodford, R
Creator: Haigh, John M
Creator: Barry, B W
Date Issued: 1983
Date: 1983
Type: Article
Identifier: vital:6450
Identifier: http://hdl.handle.net/10962/d1006637
Description: The bioavailabilities and activities of three amcinonide preparations and Betnovate cream were assessed using three multiple-dosage regimen vasoconstrictor assays in 10 volunteers. Applications were made once daily, twice daily and every alternate day with an initial three times daily loading dose applied on the first day only. Blanching responses first increased and then decreased due to tachyphylaxis. It is proposed that clinically the most advantageous dosage regimen is a once daily application with no loading dose.
Format: 5 pages
Format: pdf
Language: English
Relation: Woodford, R. and Haigh, J.M. and Barry, B.W. (1983) Possible dosage regimens for topical steroids assessed by vasoconstrictor assays using multiple applications. Dermatologica, 166 (3). pp. 136-140.

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RU Department of Pharmacy

Haigh, JM (Prof)

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