Studies on the kallikrein-kininogen system of the ostrich (Struthio camelus)
- Authors: Bothma, Leonard Frederick
- Date: 2001
- Subjects: Kallikrein , Kinins , Ostriches
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:11067 , http://hdl.handle.net/10948/275 , Kallikrein , Kinins , Ostriches
- Description: Ostrich organs/tissue/fluids were screened for plasma kallikrein-like, tissue kallikrein-like and tonin-like activity in a continuous-fluorogenic-assay system using Pro-Phe-Arg-7-amino-4-methylcoumarine, Phe- Arg-7-amino-4-methylcoumarine and Val-Leu-Arg--7-amino-4-trifluoro-methylcoumarine as substrates. Ostrich liver and kidney showed the highest specific plasma kallikrein-like activity. Ostrich adrenal glands and kidney showed the highest specific tissue kallikrein-like and tonin-like activity. Ostrich high molecular weight kininogen was purified from plasma and low molecular weight kininogen was partially purified. The N-terminal amino acid sequences of both high- and low molecular weight kininogens from ostrich plasma were determined. Ostrich plasma high molecular weight kininogen was purified as a 118 kD protein. The purified high molecular weight kininogen inhibits the cysteine proteinase papain at a ratio of one molecule HKG to two molecules of papain. Ornitho kinin-like molecules were detected in ostrich urine using reverse phase HPLC.
- Full Text:
- Date Issued: 2001
- Authors: Bothma, Leonard Frederick
- Date: 2001
- Subjects: Kallikrein , Kinins , Ostriches
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:11067 , http://hdl.handle.net/10948/275 , Kallikrein , Kinins , Ostriches
- Description: Ostrich organs/tissue/fluids were screened for plasma kallikrein-like, tissue kallikrein-like and tonin-like activity in a continuous-fluorogenic-assay system using Pro-Phe-Arg-7-amino-4-methylcoumarine, Phe- Arg-7-amino-4-methylcoumarine and Val-Leu-Arg--7-amino-4-trifluoro-methylcoumarine as substrates. Ostrich liver and kidney showed the highest specific plasma kallikrein-like activity. Ostrich adrenal glands and kidney showed the highest specific tissue kallikrein-like and tonin-like activity. Ostrich high molecular weight kininogen was purified from plasma and low molecular weight kininogen was partially purified. The N-terminal amino acid sequences of both high- and low molecular weight kininogens from ostrich plasma were determined. Ostrich plasma high molecular weight kininogen was purified as a 118 kD protein. The purified high molecular weight kininogen inhibits the cysteine proteinase papain at a ratio of one molecule HKG to two molecules of papain. Ornitho kinin-like molecules were detected in ostrich urine using reverse phase HPLC.
- Full Text:
- Date Issued: 2001
The constitutional right of access to social security
- Authors: Govindjee, Avinash
- Date: 2001
- Subjects: Social security -- Law and legislation -- South Africa , South Africa -- Social policy
- Language: English
- Type: Thesis , Masters , LLM
- Identifier: vital:11061 , http://hdl.handle.net/10948/280 , Social security -- Law and legislation -- South Africa , South Africa -- Social policy
- Description: The inclusion of the right of access to social security in the Constitution did not meet with wholehearted approval in South Africa. This right, however, is of vital importance for the future upliftment of the country. The present social security system is based upon a clear distinction between social assistance and social insurance. There is a gap in current social security provisions in that the unemployed middle aged individual is not covered. Unemployment itself is one of the greatest challenges obscuring the implementation of a comprehensive social security system. The Constitutional right is to have ‘access’ to social security and the amount of resources at the state’s disposal is directly related to increasing this right, although it is true that a number of available resources are misspent. The state must take reasonable legislative and other measures, within its available resources, to achieve the progressive realisation of the right of access to social security. The principles of solidarity and ubuntu must be cultivated so that national social development becomes a concern for all citizens. There are numerous problems facing South Africans in attaining the goal of access to social security – even if national social development does become a priority. Budgetary constraints, poverty, unemployment, HIV/Aids and foreigners are examples of these. By making social security a priority for everyone, existing ideas (almost all of which have merit) may be converted into long-term solutions for poverty and unemployment. Currently, numerous opportunities to salvage the situation are being overlooked as a result of the lack of a comprehensive and structured plan to better the access to social security. The constitutional right of access to social security is enforceable, although the jurisprudence in this field remains underdeveloped. Conditions are currently favourable, within the country and beyond its borders, for an imaginative and concerted attempt to be made to find potential solutions. It is possible for resources to be increased and for tax benefits to be incorporated for businesses which have the capacity to contribute. The issue of defence spending is controversial, but could hold the key to lowering unemployment. Should jobs be created, it is likely that they will initially be of a temporary nature. Consequently, provisions are needed to ensure some guarantee of income in the lacuna between when a job is lost and another found. Ultimately, one thing is certain: the constitutional right of access to social security will only be complete once the people who are recipients of this right make sacrifices and create corresponding duties for themselves to ensure that the next generation of inhabitants of this country are not facing similar problems. The state’s goal should be to ensure that the basic rights which all people enjoy in terms of the Constitution (in particular the other socio-economic rights) are guaranteed for the duration of their existence, even if the level of benefits received by such people is low.
- Full Text:
- Date Issued: 2001
- Authors: Govindjee, Avinash
- Date: 2001
- Subjects: Social security -- Law and legislation -- South Africa , South Africa -- Social policy
- Language: English
- Type: Thesis , Masters , LLM
- Identifier: vital:11061 , http://hdl.handle.net/10948/280 , Social security -- Law and legislation -- South Africa , South Africa -- Social policy
- Description: The inclusion of the right of access to social security in the Constitution did not meet with wholehearted approval in South Africa. This right, however, is of vital importance for the future upliftment of the country. The present social security system is based upon a clear distinction between social assistance and social insurance. There is a gap in current social security provisions in that the unemployed middle aged individual is not covered. Unemployment itself is one of the greatest challenges obscuring the implementation of a comprehensive social security system. The Constitutional right is to have ‘access’ to social security and the amount of resources at the state’s disposal is directly related to increasing this right, although it is true that a number of available resources are misspent. The state must take reasonable legislative and other measures, within its available resources, to achieve the progressive realisation of the right of access to social security. The principles of solidarity and ubuntu must be cultivated so that national social development becomes a concern for all citizens. There are numerous problems facing South Africans in attaining the goal of access to social security – even if national social development does become a priority. Budgetary constraints, poverty, unemployment, HIV/Aids and foreigners are examples of these. By making social security a priority for everyone, existing ideas (almost all of which have merit) may be converted into long-term solutions for poverty and unemployment. Currently, numerous opportunities to salvage the situation are being overlooked as a result of the lack of a comprehensive and structured plan to better the access to social security. The constitutional right of access to social security is enforceable, although the jurisprudence in this field remains underdeveloped. Conditions are currently favourable, within the country and beyond its borders, for an imaginative and concerted attempt to be made to find potential solutions. It is possible for resources to be increased and for tax benefits to be incorporated for businesses which have the capacity to contribute. The issue of defence spending is controversial, but could hold the key to lowering unemployment. Should jobs be created, it is likely that they will initially be of a temporary nature. Consequently, provisions are needed to ensure some guarantee of income in the lacuna between when a job is lost and another found. Ultimately, one thing is certain: the constitutional right of access to social security will only be complete once the people who are recipients of this right make sacrifices and create corresponding duties for themselves to ensure that the next generation of inhabitants of this country are not facing similar problems. The state’s goal should be to ensure that the basic rights which all people enjoy in terms of the Constitution (in particular the other socio-economic rights) are guaranteed for the duration of their existence, even if the level of benefits received by such people is low.
- Full Text:
- Date Issued: 2001
The distinction between a contract of employment and a contract with an independent contractor
- Authors: Slater, Henry John
- Date: 2001
- Subjects: Labor contract -- South Africa , Independent contractors -- South Africa , Contracts -- South Africa -- Cases , Liability (Law) -- South Africa , Labor laws and legislation -- South Africa
- Language: English
- Type: Thesis , Masters , LLM
- Identifier: vital:11060 , http://hdl.handle.net/10948/276 , Labor contract -- South Africa , Independent contractors -- South Africa , Contracts -- South Africa -- Cases , Liability (Law) -- South Africa , Labor laws and legislation -- South Africa
- Description: The purpose of this treatise was to determine the distinction between the contract of service (employment) and the contract of work (independent contractor). A comprehensive literary survey was undertaken so as to establish if such a distinction does indeed exist. A logical point of departure was to study the contract of service and determine how the employment relationship is established by it. It is also necessary to establish under what circumstances a contract may be terminated and what the rights and obligations of the parties to the contract were. The contract between the parties will determine remedies to the breach of contract or applicability of labour legislation. It is also necessary to establish the definition of an employee under various statutes so as to understand what remedies exist should rights be infringed upon. Statutes considered include the Constitution of the Republic of South Africa, Labour Relations Act, Basic Conditions of Employment Act, Employment Equity Act, Unemployment Insurance Act, Compensation for Occupational Injuries and Diseases Act, Skills Development Act and the Income Tax Act. The effect of insolvency of the employer on the employee is also discussed. Outsourcing has played a major role in the emergence of the independent contractor. This phenomenon is considered from the point of the employer in terms of the reasons for choosing the option of outsourcing and the associated risks. The employee perspective is also dealt with in terms of why an employee would change his/her employment status. The various tests historically applied to determine the status of a worker is also discussed. These include the control, organisation, dominant impression and economic tests. Currently the dominant impression test is the one that is being applied to determine the employment relationship. Extensive reference was made to case law. United States of America cases are referred to with specific reference to the 20 Factor Test applied by the Internal Revenue Service. South African case law is dealt wit in terms of enforcement of Bargaining Council agreements, commission-earning persons, payment for services rendered, the intention of the parties and the identity of the true employer. The emergence of the dependent contractor is also addressed. This form of worker normally falls outside of the protection of labour legislation and social security. Amendments have been proposed to various statutes to remedy the situation in South Africa. A final aspect that is dealt with is that of vicarious liability. The applicability of this aspect lies in the liability of the employer for damages inflicted by the employee.
- Full Text:
- Date Issued: 2001
- Authors: Slater, Henry John
- Date: 2001
- Subjects: Labor contract -- South Africa , Independent contractors -- South Africa , Contracts -- South Africa -- Cases , Liability (Law) -- South Africa , Labor laws and legislation -- South Africa
- Language: English
- Type: Thesis , Masters , LLM
- Identifier: vital:11060 , http://hdl.handle.net/10948/276 , Labor contract -- South Africa , Independent contractors -- South Africa , Contracts -- South Africa -- Cases , Liability (Law) -- South Africa , Labor laws and legislation -- South Africa
- Description: The purpose of this treatise was to determine the distinction between the contract of service (employment) and the contract of work (independent contractor). A comprehensive literary survey was undertaken so as to establish if such a distinction does indeed exist. A logical point of departure was to study the contract of service and determine how the employment relationship is established by it. It is also necessary to establish under what circumstances a contract may be terminated and what the rights and obligations of the parties to the contract were. The contract between the parties will determine remedies to the breach of contract or applicability of labour legislation. It is also necessary to establish the definition of an employee under various statutes so as to understand what remedies exist should rights be infringed upon. Statutes considered include the Constitution of the Republic of South Africa, Labour Relations Act, Basic Conditions of Employment Act, Employment Equity Act, Unemployment Insurance Act, Compensation for Occupational Injuries and Diseases Act, Skills Development Act and the Income Tax Act. The effect of insolvency of the employer on the employee is also discussed. Outsourcing has played a major role in the emergence of the independent contractor. This phenomenon is considered from the point of the employer in terms of the reasons for choosing the option of outsourcing and the associated risks. The employee perspective is also dealt with in terms of why an employee would change his/her employment status. The various tests historically applied to determine the status of a worker is also discussed. These include the control, organisation, dominant impression and economic tests. Currently the dominant impression test is the one that is being applied to determine the employment relationship. Extensive reference was made to case law. United States of America cases are referred to with specific reference to the 20 Factor Test applied by the Internal Revenue Service. South African case law is dealt wit in terms of enforcement of Bargaining Council agreements, commission-earning persons, payment for services rendered, the intention of the parties and the identity of the true employer. The emergence of the dependent contractor is also addressed. This form of worker normally falls outside of the protection of labour legislation and social security. Amendments have been proposed to various statutes to remedy the situation in South Africa. A final aspect that is dealt with is that of vicarious liability. The applicability of this aspect lies in the liability of the employer for damages inflicted by the employee.
- Full Text:
- Date Issued: 2001
The goddess, the witch and the bitch : three studies in the perception of women
- Authors: Hare, Nicola Tracy
- Date: 2001
- Subjects: Feminism in literature , Women's rights in literature , Feminism and literature , Patriarchy in literature
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:10986 , http://hdl.handle.net/10948/278 , Feminism in literature , Women's rights in literature , Feminism and literature , Patriarchy in literature
- Description: In the minds of many people all over the world, women are ‘second class citizens’, standing accused of the downfall of mankind ever since Eve allegedly ate the apple. Even amongst those who do not openly denigrate women, there are many who do so in other, more subtle ways even if they are unaware of it. This study proposes to challenge such a view of women by exposing the ways in which perceptions of women are constructed by society, which frequently wants to maintain the status quo of male dominance. This study employs a feminist approach in examining this gynocentric theme, along with cultural studies which, with its focus on power relations and ways of decentring power structures, is also clearly of use. In addition, this multidisciplinary approach of cultural studies offers the possibility of studying literary texts as well as popular culture. Three specific time periods are examined, with a view to uncovering negative perceptions of women and ways that women can resist such attempts to control them. In chapter one, the focus turns to contemporary perceptions of prehistoric women and the ways that so-called ‘objective’ science has failed to represent women accurately. Similarly, ‘objective’ accounts of Goddess-worship – which frequently fail to examine this phenomenon adequately – are revisited. Alice Walker’s The Temple of My Familiar (1989) is discussed as a text which acts as a site of resistance to societally-informed perceptions. Chapter two continues this investigation by turning to the concept of the witch and its maligned association with women. Woman and witchcraft, having been associated for centuries, are investigated as a pairing which frequently results because iii of attempts to control women by androcentric society. In such situations, the practising of witchcraft can actually become a form of resistance to patriarchy. The pernicious effect of society’s need to purge itself – by witch hunts – of witches is also investigated. The Devil’s Chimney (1997) by Anne Landsman and “The prophetess” (1994) by Njabulo S. Ndebele are discussed as texts which examine fictionalised South African versions of this phenomenon. Sinead O’Connor, the Irish singer, is the ‘bitch’ discussed in chapter three. She is examined as a woman who offers strong and on-going resistance to patriarchal ways of thinking which would ‘box’ women in. This singer refuses to accept societal roles which are offered to women and so offers means of resistance to patriarchy, many of which are discussed in this chapter. This study concludes that it is the responsibility of women to resist patriarchy and to define roles for themselves. The three chapters examine various means of resistance and offer women insight into the forms of opposition they themselves can take.
- Full Text:
- Date Issued: 2001
- Authors: Hare, Nicola Tracy
- Date: 2001
- Subjects: Feminism in literature , Women's rights in literature , Feminism and literature , Patriarchy in literature
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:10986 , http://hdl.handle.net/10948/278 , Feminism in literature , Women's rights in literature , Feminism and literature , Patriarchy in literature
- Description: In the minds of many people all over the world, women are ‘second class citizens’, standing accused of the downfall of mankind ever since Eve allegedly ate the apple. Even amongst those who do not openly denigrate women, there are many who do so in other, more subtle ways even if they are unaware of it. This study proposes to challenge such a view of women by exposing the ways in which perceptions of women are constructed by society, which frequently wants to maintain the status quo of male dominance. This study employs a feminist approach in examining this gynocentric theme, along with cultural studies which, with its focus on power relations and ways of decentring power structures, is also clearly of use. In addition, this multidisciplinary approach of cultural studies offers the possibility of studying literary texts as well as popular culture. Three specific time periods are examined, with a view to uncovering negative perceptions of women and ways that women can resist such attempts to control them. In chapter one, the focus turns to contemporary perceptions of prehistoric women and the ways that so-called ‘objective’ science has failed to represent women accurately. Similarly, ‘objective’ accounts of Goddess-worship – which frequently fail to examine this phenomenon adequately – are revisited. Alice Walker’s The Temple of My Familiar (1989) is discussed as a text which acts as a site of resistance to societally-informed perceptions. Chapter two continues this investigation by turning to the concept of the witch and its maligned association with women. Woman and witchcraft, having been associated for centuries, are investigated as a pairing which frequently results because iii of attempts to control women by androcentric society. In such situations, the practising of witchcraft can actually become a form of resistance to patriarchy. The pernicious effect of society’s need to purge itself – by witch hunts – of witches is also investigated. The Devil’s Chimney (1997) by Anne Landsman and “The prophetess” (1994) by Njabulo S. Ndebele are discussed as texts which examine fictionalised South African versions of this phenomenon. Sinead O’Connor, the Irish singer, is the ‘bitch’ discussed in chapter three. She is examined as a woman who offers strong and on-going resistance to patriarchal ways of thinking which would ‘box’ women in. This singer refuses to accept societal roles which are offered to women and so offers means of resistance to patriarchy, many of which are discussed in this chapter. This study concludes that it is the responsibility of women to resist patriarchy and to define roles for themselves. The three chapters examine various means of resistance and offer women insight into the forms of opposition they themselves can take.
- Full Text:
- Date Issued: 2001
The right of the HIV/AIDS patient to treatment
- Authors: Hoffmann, Toinette
- Date: 2001
- Subjects: AIDS (Disease) -- Patients -- Legal status, Laws, etc. -- South Africa , Hiv-positive Persons -- Legal status, Laws, etc. -- South Africa , AIDS (Disease) -- Government policy -- South Africa , AIDS (Disease) -- Treatment , AIDS (Disease) -- Social aspects
- Language: English
- Type: Thesis , Masters , LLM
- Identifier: vital:11042 , http://hdl.handle.net/10948/277 , AIDS (Disease) -- Patients -- Legal status, Laws, etc. -- South Africa , Hiv-positive Persons -- Legal status, Laws, etc. -- South Africa , AIDS (Disease) -- Government policy -- South Africa , AIDS (Disease) -- Treatment , AIDS (Disease) -- Social aspects
- Description: The objective of this treatise is to establish whether a right to social security exists in South Africa, which would entitle HIV positive persons in South Africa citizens to medical care. A study was made of various articles in journals and on the Internet to determine the South African government's policy on a right to social security and to providing medical treatment. It was found that South Africa lacks an integrated, holistic approach to social security and does not guarantee the right to social security, merely the right to have access to social security. The same was found with the right to medical care. Although there seems to be a general right to medical care which extends to and includes HIV-positive patients, the state merely guarantees the right to apply for medical treatment but does not guarantee the granting thereof. It is submitted that the Department of Health's refusal to implement a vertical transmission prevention programme and the failure to offer treatment as an alternative, for whatever reason, is "penny wise and pound foolish". In the long run more money is spent dealing with pediatric AIDS. It was further found that although the government attempted to lay a groundwork with the formulation and acceptance of the national AIDS plan, the successful implementation thereof is seriously hindered due to the lack of inter- and intra-departmental collaboration, essential health services and funding.
- Full Text:
- Date Issued: 2001
- Authors: Hoffmann, Toinette
- Date: 2001
- Subjects: AIDS (Disease) -- Patients -- Legal status, Laws, etc. -- South Africa , Hiv-positive Persons -- Legal status, Laws, etc. -- South Africa , AIDS (Disease) -- Government policy -- South Africa , AIDS (Disease) -- Treatment , AIDS (Disease) -- Social aspects
- Language: English
- Type: Thesis , Masters , LLM
- Identifier: vital:11042 , http://hdl.handle.net/10948/277 , AIDS (Disease) -- Patients -- Legal status, Laws, etc. -- South Africa , Hiv-positive Persons -- Legal status, Laws, etc. -- South Africa , AIDS (Disease) -- Government policy -- South Africa , AIDS (Disease) -- Treatment , AIDS (Disease) -- Social aspects
- Description: The objective of this treatise is to establish whether a right to social security exists in South Africa, which would entitle HIV positive persons in South Africa citizens to medical care. A study was made of various articles in journals and on the Internet to determine the South African government's policy on a right to social security and to providing medical treatment. It was found that South Africa lacks an integrated, holistic approach to social security and does not guarantee the right to social security, merely the right to have access to social security. The same was found with the right to medical care. Although there seems to be a general right to medical care which extends to and includes HIV-positive patients, the state merely guarantees the right to apply for medical treatment but does not guarantee the granting thereof. It is submitted that the Department of Health's refusal to implement a vertical transmission prevention programme and the failure to offer treatment as an alternative, for whatever reason, is "penny wise and pound foolish". In the long run more money is spent dealing with pediatric AIDS. It was further found that although the government attempted to lay a groundwork with the formulation and acceptance of the national AIDS plan, the successful implementation thereof is seriously hindered due to the lack of inter- and intra-departmental collaboration, essential health services and funding.
- Full Text:
- Date Issued: 2001
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