A step forward in defining Hsp90s as potential drug targets for human parasitic diseases
- Authors: Faya, Ngonidzashe
- Date: 2014
- Subjects: Heat shock proteins -- Research , Malaria -- Chemotherapy -- Research , Antimalarials -- Development -- Research , Parasitic diseases -- Research , Plasmodium
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4110 , http://hdl.handle.net/10962/d1012993
- Description: Parasitic diseases remain a health burden affecting more than 500 million people worldwide with malaria having the highest mortality rate. The parasites can be transferred to the human bodies either through the mouth by ingestion of contaminated food and water or through the skin by bug bites or direct contact to environments harbouring them. Epidemiological control seems to be impossible since there is failure to control the insect vectors as well as practice of hygiene. Therefore, this has led to the development of a number of vaccines, chemotherapy and disease control programs. However, parasites have increasingly developed resistance to traditionally used anti-parasitic drugs and due to that fact there is need for alternative medication for parasitic diseases. Heat shock protein 90 (Hsp90) facilitates the folding of proteins in all living cells and their role is more important to parasites because of their environmental changes, from vector to host. Hsp90s play a major role; therefore this justifies the need for a deeper analysis of the parasitic Hsp90s. Recent studies have revealed that, the Plasmodium sp. Hsp90 has an extended linker region which increases the protein’s affinity for ATP and its inhibitors. Therefore we hypothesize that there are also significant features in other parasitic Hsp90s which would lead to Hsp90 being defined as potential drug targets. In the present study an attempt was made to gain more insight into the differences in primary structure of human and parasitic Hsp90s. The sequences were retrieved from the NCBI database and analysis was done in three groups basing on the localization of the Hsp90. The physicochemical properties were calculated and in every group, the protozoan Hsp90s showed significant differences when compared to the human orthologs. Multiple sequence alignments (MSA) showed that endoplasmic reticulum Hsp90s have an extended region in the middle domain indicating their ability to bind to a unique subset of client proteins. Sequence identities between the human and parasites showed that the protozoan Hsp90s are less related to the human Hsp90s as compared to the other parasites. Likewise, motif analysis showed the trypanosomatids and apicomplexan groups have their own unique set of motifs and they were grouped together in the phylogenetic analysis. Phylogenetic analysis also showed that, the protozoan Hsp90s forms their own clades in each group while the helminths did not form in endoplasmic reticulum group. In this study, we concluded that, Hsp90 can be a potential drug target for the protozoan species and more specifically those from the apicomplexan and trypanosomatids groups.
- Full Text:
- Date Issued: 2014
- Authors: Faya, Ngonidzashe
- Date: 2014
- Subjects: Heat shock proteins -- Research , Malaria -- Chemotherapy -- Research , Antimalarials -- Development -- Research , Parasitic diseases -- Research , Plasmodium
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4110 , http://hdl.handle.net/10962/d1012993
- Description: Parasitic diseases remain a health burden affecting more than 500 million people worldwide with malaria having the highest mortality rate. The parasites can be transferred to the human bodies either through the mouth by ingestion of contaminated food and water or through the skin by bug bites or direct contact to environments harbouring them. Epidemiological control seems to be impossible since there is failure to control the insect vectors as well as practice of hygiene. Therefore, this has led to the development of a number of vaccines, chemotherapy and disease control programs. However, parasites have increasingly developed resistance to traditionally used anti-parasitic drugs and due to that fact there is need for alternative medication for parasitic diseases. Heat shock protein 90 (Hsp90) facilitates the folding of proteins in all living cells and their role is more important to parasites because of their environmental changes, from vector to host. Hsp90s play a major role; therefore this justifies the need for a deeper analysis of the parasitic Hsp90s. Recent studies have revealed that, the Plasmodium sp. Hsp90 has an extended linker region which increases the protein’s affinity for ATP and its inhibitors. Therefore we hypothesize that there are also significant features in other parasitic Hsp90s which would lead to Hsp90 being defined as potential drug targets. In the present study an attempt was made to gain more insight into the differences in primary structure of human and parasitic Hsp90s. The sequences were retrieved from the NCBI database and analysis was done in three groups basing on the localization of the Hsp90. The physicochemical properties were calculated and in every group, the protozoan Hsp90s showed significant differences when compared to the human orthologs. Multiple sequence alignments (MSA) showed that endoplasmic reticulum Hsp90s have an extended region in the middle domain indicating their ability to bind to a unique subset of client proteins. Sequence identities between the human and parasites showed that the protozoan Hsp90s are less related to the human Hsp90s as compared to the other parasites. Likewise, motif analysis showed the trypanosomatids and apicomplexan groups have their own unique set of motifs and they were grouped together in the phylogenetic analysis. Phylogenetic analysis also showed that, the protozoan Hsp90s forms their own clades in each group while the helminths did not form in endoplasmic reticulum group. In this study, we concluded that, Hsp90 can be a potential drug target for the protozoan species and more specifically those from the apicomplexan and trypanosomatids groups.
- Full Text:
- Date Issued: 2014
A study exploring the relationship between employee happiness and financial performance within a South African financial institution
- Authors: Waugh, Geoffrey William
- Date: 2014
- Subjects: Financial institutions -- South Africa , Employee motivation , Financial institutions -- Ratings and rankings , Banks and banking -- South Africa , Bank employees -- South Africa , Job satisfaction
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:827 , http://hdl.handle.net/10962/d1012080
- Description: This research is an investigation of the relationship between employees 'happiness' and the financial performance of a financial services organisation in South Africa. As a component of the financial services industry the banking sector contributes greatly to the economic growth of the country. The South African Banking sector is concentrated and highly competitive. It is vital for banks to maintain competitiveness and ever increasing global competition adds further pressure on organisations to financially perform so as to meet the demands of their shareholders. The literature that has been reviewed and previous research suggest that employee 'happiness' is a vital variable influencing the performance and success of individuals. Organisational performance will be measured in terms of financial performance for the purposes of this research. The concept of financial performance and 'happiness' are discussed and a questionnaire based on the Satisfaction With Life Scale (Diener et al,1985) is used to determine the levels of 'happiness' at selected branches within the institution. The individual branches financial performance is determined via calculating selected ratios, namely cumulative leverage, cost to income ratio and net yield. An analysis of correlation was conducted to establish whether or not a relationship of statistical significance exists between employee 'happiness' and financial performance. It was concluded that there is no relationship of statistical significance between employee 'happiness' and the financial performance of branches within the organisation, it was suggested that other factors exert a much greater influence over financial performance. Some of these factors influencing financial performance are discussed and recommendations for further research are made.
- Full Text:
- Date Issued: 2014
- Authors: Waugh, Geoffrey William
- Date: 2014
- Subjects: Financial institutions -- South Africa , Employee motivation , Financial institutions -- Ratings and rankings , Banks and banking -- South Africa , Bank employees -- South Africa , Job satisfaction
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:827 , http://hdl.handle.net/10962/d1012080
- Description: This research is an investigation of the relationship between employees 'happiness' and the financial performance of a financial services organisation in South Africa. As a component of the financial services industry the banking sector contributes greatly to the economic growth of the country. The South African Banking sector is concentrated and highly competitive. It is vital for banks to maintain competitiveness and ever increasing global competition adds further pressure on organisations to financially perform so as to meet the demands of their shareholders. The literature that has been reviewed and previous research suggest that employee 'happiness' is a vital variable influencing the performance and success of individuals. Organisational performance will be measured in terms of financial performance for the purposes of this research. The concept of financial performance and 'happiness' are discussed and a questionnaire based on the Satisfaction With Life Scale (Diener et al,1985) is used to determine the levels of 'happiness' at selected branches within the institution. The individual branches financial performance is determined via calculating selected ratios, namely cumulative leverage, cost to income ratio and net yield. An analysis of correlation was conducted to establish whether or not a relationship of statistical significance exists between employee 'happiness' and financial performance. It was concluded that there is no relationship of statistical significance between employee 'happiness' and the financial performance of branches within the organisation, it was suggested that other factors exert a much greater influence over financial performance. Some of these factors influencing financial performance are discussed and recommendations for further research are made.
- Full Text:
- Date Issued: 2014
A Study of grade 3 teachers' practices of developing learners' comprehension skills when teaching reading of isiXhosa in one selected junior primary school at Mdatsane in the Eastern cape: a case study
- Authors: Filita, Mandisa
- Date: 2014
- Subjects: Reading comprehension , Xhosa language , Teachers -- Training of -- South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/26448 , vital:65318
- Description: The problem of reading in South African schools has attracted the growing attention of researchers in South Africa and the entire world. Learners’ inability to read isiXhosa with understanding has become of major concern to the teachers, parents and the DoE. The root of the problem has been identified as the ineffective teaching of reading of isiXhosa in the schools, which result in learners’ consequent inability to independently apply comprehension skills to learn from reading across the curriculum. Furthermore, systemic barriers that exist in the education system seem to be another reason for learners’ reading problems in isiXhosa. Also there is the problem of the inadequately trained teachers in the home language of learners (isiXhosa) as they seemingly lack capacity to develop learners’ literacy to effective levels. In addition, many learners come from deprived print environments where texts are seldom part of their daily experience. The main aim of this study was to interrogate the practices undertaken by teachers in trying to develop comprehension skills of learners when reading in isiXhosa and the value they attach to reading generally and to the reading of isiXhosa in particular. The support teachers get from relevant stakeholders was also considered. The overall approach used was a qualitative approach. The study was structured according to the case study mode of enquiry, using the interpretive paradigm. The sampling used was purposive as I purposefully selected grade 3 teachers, as grade 3 is an exit grade in foundation phase. Furthermore, convenience sampling was also used for easy access, as the research site was the school where I work. The instruments used for data collection were semi-structured interviews and observations that were conducted in one junior primary school in a township context with four grade 3 teachers. It was found that as much as teachers’ practices have a contributing effect on learners’ inability to read isiXhosa with understanding, there are also various other factors which multiply the problem. The study reveals the following main findings: Firstly, the teachers believe that reading is a very important skill that needs to be developed with learners as all other learning is based on it. , Thesis (MEd) -- Faculty of Education, 2014
- Full Text:
- Date Issued: 2014
- Authors: Filita, Mandisa
- Date: 2014
- Subjects: Reading comprehension , Xhosa language , Teachers -- Training of -- South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/26448 , vital:65318
- Description: The problem of reading in South African schools has attracted the growing attention of researchers in South Africa and the entire world. Learners’ inability to read isiXhosa with understanding has become of major concern to the teachers, parents and the DoE. The root of the problem has been identified as the ineffective teaching of reading of isiXhosa in the schools, which result in learners’ consequent inability to independently apply comprehension skills to learn from reading across the curriculum. Furthermore, systemic barriers that exist in the education system seem to be another reason for learners’ reading problems in isiXhosa. Also there is the problem of the inadequately trained teachers in the home language of learners (isiXhosa) as they seemingly lack capacity to develop learners’ literacy to effective levels. In addition, many learners come from deprived print environments where texts are seldom part of their daily experience. The main aim of this study was to interrogate the practices undertaken by teachers in trying to develop comprehension skills of learners when reading in isiXhosa and the value they attach to reading generally and to the reading of isiXhosa in particular. The support teachers get from relevant stakeholders was also considered. The overall approach used was a qualitative approach. The study was structured according to the case study mode of enquiry, using the interpretive paradigm. The sampling used was purposive as I purposefully selected grade 3 teachers, as grade 3 is an exit grade in foundation phase. Furthermore, convenience sampling was also used for easy access, as the research site was the school where I work. The instruments used for data collection were semi-structured interviews and observations that were conducted in one junior primary school in a township context with four grade 3 teachers. It was found that as much as teachers’ practices have a contributing effect on learners’ inability to read isiXhosa with understanding, there are also various other factors which multiply the problem. The study reveals the following main findings: Firstly, the teachers believe that reading is a very important skill that needs to be developed with learners as all other learning is based on it. , Thesis (MEd) -- Faculty of Education, 2014
- Full Text:
- Date Issued: 2014
A study of South African computer users' password usage habits and attitude towards password security
- Authors: Friendman, Brandon
- Date: 2014
- Subjects: Computers -- Access control -- Passwords , Computer users -- Attitudes , Internet -- Access control , Internet -- Security measures , Internet -- Management , Data protection
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: vital:4700
- Description: The challenge of having to create and remember a secure password for each user account has become a problem for many computer users and can lead to bad password management practices. Simpler and less secure passwords are often selected and are regularly reused across multiple user accounts. Computer users within corporations and institutions are subject to password policies, policies which require users to create passwords of a specified length and composition and change passwords regularly. These policies often prevent users from reusing previous selected passwords. Security vendors and professionals have sought to improve or even replace password authentication. Technologies such as multi-factor authentication and single sign-on have been developed to complement or even replace password authentication. The objective of the study was to investigate the password habits of South African computer and internet users. The aim was to assess their attitudes toward password security, to determine whether password policies a↵ect the manner in which they manage their passwords and to investigate their exposure to alternate authentication technologies. The results from the online survey demonstrated that password practices of the participants across their professional and personal contexts were generally insecure. Participants often used shorter, simpler and ultimately less secure passwords. Participants would try to memorise all of their passwords or reuse the same password on most of their accounts. Many participants had not received any security awareness training, and additional security technologies (such as multi-factor authentication or password managers) were seldom used or provided to them. The password policies encountered by the participants in their organisations did little towards encouraging the users to apply more secure password practices. Users lack the knowledge and understanding about password security as they had received little or no training pertaining to it.
- Full Text:
- Date Issued: 2014
- Authors: Friendman, Brandon
- Date: 2014
- Subjects: Computers -- Access control -- Passwords , Computer users -- Attitudes , Internet -- Access control , Internet -- Security measures , Internet -- Management , Data protection
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: vital:4700
- Description: The challenge of having to create and remember a secure password for each user account has become a problem for many computer users and can lead to bad password management practices. Simpler and less secure passwords are often selected and are regularly reused across multiple user accounts. Computer users within corporations and institutions are subject to password policies, policies which require users to create passwords of a specified length and composition and change passwords regularly. These policies often prevent users from reusing previous selected passwords. Security vendors and professionals have sought to improve or even replace password authentication. Technologies such as multi-factor authentication and single sign-on have been developed to complement or even replace password authentication. The objective of the study was to investigate the password habits of South African computer and internet users. The aim was to assess their attitudes toward password security, to determine whether password policies a↵ect the manner in which they manage their passwords and to investigate their exposure to alternate authentication technologies. The results from the online survey demonstrated that password practices of the participants across their professional and personal contexts were generally insecure. Participants often used shorter, simpler and ultimately less secure passwords. Participants would try to memorise all of their passwords or reuse the same password on most of their accounts. Many participants had not received any security awareness training, and additional security technologies (such as multi-factor authentication or password managers) were seldom used or provided to them. The password policies encountered by the participants in their organisations did little towards encouraging the users to apply more secure password practices. Users lack the knowledge and understanding about password security as they had received little or no training pertaining to it.
- Full Text:
- Date Issued: 2014
A study of spherical solutions in chameleon scalar-tensor theories
- Authors: Mohapi, Neo
- Date: 2014
- Subjects: Scalar field theory , Equivalence principle (Physics) , General relativity (Physics) , Bosons , Dark energy (Astronomy) , Galactic dynamics
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5428 , http://hdl.handle.net/10962/d1013315
- Description: The equivalence principle has proven to be central to theories of gravity, with General Relativity being the simplest and most elegant theory to embody the principle. Most alternative theories of gravity struggle to satisfy the principle and still be distinct from GR. Extensions of cosmological and quantum theories question the irrefutably of the equivalence at every scale. The possibility of an equivalence principle violation at galactic scales would be an exciting prospect. In this thesis, we will carefully examine the equivalence principle through the study of chameleon scalar-tensor theories, this will include solutions for hypothetical stars known as boson stars. Such theories find varied application, especially in cosmology, where they model dark energy and inflation. The AWE hypothesis, is an instance of this. It is a nonuniversally coupled model in which violations of the equivalence principle on galactic scales may be apparent. We investigate spherically symmetric and static solutions within the framework of this theory. The constraints obtained from galactic rotation curves results in values of the couplings that show no significant violation of the equivalence principle or values consistent with a theory of dark energy
- Full Text:
- Date Issued: 2014
- Authors: Mohapi, Neo
- Date: 2014
- Subjects: Scalar field theory , Equivalence principle (Physics) , General relativity (Physics) , Bosons , Dark energy (Astronomy) , Galactic dynamics
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5428 , http://hdl.handle.net/10962/d1013315
- Description: The equivalence principle has proven to be central to theories of gravity, with General Relativity being the simplest and most elegant theory to embody the principle. Most alternative theories of gravity struggle to satisfy the principle and still be distinct from GR. Extensions of cosmological and quantum theories question the irrefutably of the equivalence at every scale. The possibility of an equivalence principle violation at galactic scales would be an exciting prospect. In this thesis, we will carefully examine the equivalence principle through the study of chameleon scalar-tensor theories, this will include solutions for hypothetical stars known as boson stars. Such theories find varied application, especially in cosmology, where they model dark energy and inflation. The AWE hypothesis, is an instance of this. It is a nonuniversally coupled model in which violations of the equivalence principle on galactic scales may be apparent. We investigate spherically symmetric and static solutions within the framework of this theory. The constraints obtained from galactic rotation curves results in values of the couplings that show no significant violation of the equivalence principle or values consistent with a theory of dark energy
- Full Text:
- Date Issued: 2014
A study of the Consumption Capital Asset Pricing Model's appilcability across four countries
- Spurway, Kayleigh Fay Nanette
- Authors: Spurway, Kayleigh Fay Nanette
- Date: 2014
- Subjects: Econometric models , Capital assets pricing model , Investments , Econometric models -- Germany , Econometric models -- South Africa , Econometric models -- Great Britain , Econometric models -- United States
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:1095 , http://hdl.handle.net/10962/d1013016
- Description: Historically, the Consumption Capital Asset Pricing Method (C-CAPM) has performed poorly in that estimated parameters are implausible, model restrictions are often rejected and inferences appear to be very sensitive to the choice of economic agents' preferences. In this study, we estimate and test the C-CAPM with Constant Relative Risk Aversion (CRRA) using time series data from Germany, South Africa, Britain and America during relatively short time periods with the latest available data sets. Hansen's GMM approach is applied to estimate the parameters arising from this model. In general, estimated parameters fall outside the bounds specified by Lund & Engsted (1996) and Cuthbertson & Nitzsche (2004), even though the models are not rejected by the J-test and are associated with relatively small minimum distances.
- Full Text:
- Date Issued: 2014
- Authors: Spurway, Kayleigh Fay Nanette
- Date: 2014
- Subjects: Econometric models , Capital assets pricing model , Investments , Econometric models -- Germany , Econometric models -- South Africa , Econometric models -- Great Britain , Econometric models -- United States
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:1095 , http://hdl.handle.net/10962/d1013016
- Description: Historically, the Consumption Capital Asset Pricing Method (C-CAPM) has performed poorly in that estimated parameters are implausible, model restrictions are often rejected and inferences appear to be very sensitive to the choice of economic agents' preferences. In this study, we estimate and test the C-CAPM with Constant Relative Risk Aversion (CRRA) using time series data from Germany, South Africa, Britain and America during relatively short time periods with the latest available data sets. Hansen's GMM approach is applied to estimate the parameters arising from this model. In general, estimated parameters fall outside the bounds specified by Lund & Engsted (1996) and Cuthbertson & Nitzsche (2004), even though the models are not rejected by the J-test and are associated with relatively small minimum distances.
- Full Text:
- Date Issued: 2014
A study of the corporate social investment distribution and spending by selected corporates in the Eastern Cape
- Authors: Tetyana, Sakhiwo
- Date: 2014
- Subjects: Investments -- Moral and ethical aspects -- South Africa -- Eastern Cape , Sustainable development -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9203 , http://hdl.handle.net/10948/d1020423
- Description: Corporate Social Investment (CSI) presents a platform for the business sector in South Africa to respond to challenges facing the Eastern Cape. Challenges facing this province are well documented, and it is important to measure and quantify how the business sector in South Africa currently contributes towards addressing those challenges. The Eastern Cape remains by and large undeveloped, with economic activity well below economic potential. Currently, economic activity is concentrated in Port Elizabeth, East London and Mthatha. Notwithstanding economic growth, high levels of unemployment and poverty persist, particularly in the rural areas where two-thirds of the population reside. The research study purposely sampled the top 30 companies from the top 100 listed in Trialogue. A total of 14 questionnaires were completed and returned by respondents. Five CSI managers were randomly selected from the 30 companies for in-depth interviews. The purpose of this exercise was to solicit further views to enable substantive triangulation of data from other sources. The research reveals that corporate groups in South Africa use different but complementary models and strategies in contributing towards poverty reduction. Education, particularly support for secondary school technology and science tuition, and also early childhood development (ECD), constitute key intervention areas by corporations in the Eastern Cape. This is closely followed by economic inclusion or enterprise development. There is no demonstrable evidence that corporate social investment in South Africa is informed by a coherent theoretical framework. The study revealed that education receives the largest share of CSI budgets in the Eastern Cape. Within education, mathematics and science is the most supported sub-programme focus area. This is followed by higher education which is also a preferred sub-programme focus area. A total of 40 percent of CSI spending has been channeled towards rural areas and towns in the former Transkei area. The ‘Mandela factor’ also plays an influential role in thedistribution of CSI spending, especially in the rural areas of the former Transkei. Donations ‘in kind’ are mostly distributed in urban areas.
- Full Text:
- Date Issued: 2014
- Authors: Tetyana, Sakhiwo
- Date: 2014
- Subjects: Investments -- Moral and ethical aspects -- South Africa -- Eastern Cape , Sustainable development -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9203 , http://hdl.handle.net/10948/d1020423
- Description: Corporate Social Investment (CSI) presents a platform for the business sector in South Africa to respond to challenges facing the Eastern Cape. Challenges facing this province are well documented, and it is important to measure and quantify how the business sector in South Africa currently contributes towards addressing those challenges. The Eastern Cape remains by and large undeveloped, with economic activity well below economic potential. Currently, economic activity is concentrated in Port Elizabeth, East London and Mthatha. Notwithstanding economic growth, high levels of unemployment and poverty persist, particularly in the rural areas where two-thirds of the population reside. The research study purposely sampled the top 30 companies from the top 100 listed in Trialogue. A total of 14 questionnaires were completed and returned by respondents. Five CSI managers were randomly selected from the 30 companies for in-depth interviews. The purpose of this exercise was to solicit further views to enable substantive triangulation of data from other sources. The research reveals that corporate groups in South Africa use different but complementary models and strategies in contributing towards poverty reduction. Education, particularly support for secondary school technology and science tuition, and also early childhood development (ECD), constitute key intervention areas by corporations in the Eastern Cape. This is closely followed by economic inclusion or enterprise development. There is no demonstrable evidence that corporate social investment in South Africa is informed by a coherent theoretical framework. The study revealed that education receives the largest share of CSI budgets in the Eastern Cape. Within education, mathematics and science is the most supported sub-programme focus area. This is followed by higher education which is also a preferred sub-programme focus area. A total of 40 percent of CSI spending has been channeled towards rural areas and towns in the former Transkei area. The ‘Mandela factor’ also plays an influential role in thedistribution of CSI spending, especially in the rural areas of the former Transkei. Donations ‘in kind’ are mostly distributed in urban areas.
- Full Text:
- Date Issued: 2014
A study of the impact of the St. Mary's Development and Care Centre on communities in Grahamstown
- Authors: Booth, Kaylene Lucinda
- Date: 2014
- Subjects: Community-based social services -- South Africa -- Grahamstown , Community development -- South Africa -- Grahamstown
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9193 , http://hdl.handle.net/10948/d1020369
- Description: The study is made in an attempt to evaluate a Non-Profit Organisation established 30 years ago. The organisation is called The St. Mary’s Development and Care Centre. This centre, amongst others, was established in 1982 by a true humanitarian, Mrs Thelma Henderson, and has since had more than 2250 children and lots more families in its care. The research aims to explore and evaluate the impact that the centre has had on the families and communities in Grahamstown. The evaluation is done as part of the current manager’s strategy to assess the strengths of the organisation and to build on the efficacy of the organisation. The researcher understands impact as any change whether positive or negative. This, from a social science perspective, is experienced by the person on a personal level and the effects in different families cannot be measured with a universal measure. Theory proves that because people are at varying levels of development, they therefore experience change and thus impact, differently. With the use of the grounded theory method comprising of systematic, inductive and comparative approaches for conducting inquiry for the purpose of constructing theory (Bryant & Charmaz 2007: 1) the research found that people have experienced change at different levels. This information, triangulated against previous research, validated the claims that child sponsorship at an NGO level indeed has benefits for the children involved in their programs. Therefore this evaluation paper draws the conclusion through similarities found and qualitative personal views that the St. Mary’s Development and Care Centre has indeed had an impact on the Grahamstown community.
- Full Text:
- Date Issued: 2014
- Authors: Booth, Kaylene Lucinda
- Date: 2014
- Subjects: Community-based social services -- South Africa -- Grahamstown , Community development -- South Africa -- Grahamstown
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9193 , http://hdl.handle.net/10948/d1020369
- Description: The study is made in an attempt to evaluate a Non-Profit Organisation established 30 years ago. The organisation is called The St. Mary’s Development and Care Centre. This centre, amongst others, was established in 1982 by a true humanitarian, Mrs Thelma Henderson, and has since had more than 2250 children and lots more families in its care. The research aims to explore and evaluate the impact that the centre has had on the families and communities in Grahamstown. The evaluation is done as part of the current manager’s strategy to assess the strengths of the organisation and to build on the efficacy of the organisation. The researcher understands impact as any change whether positive or negative. This, from a social science perspective, is experienced by the person on a personal level and the effects in different families cannot be measured with a universal measure. Theory proves that because people are at varying levels of development, they therefore experience change and thus impact, differently. With the use of the grounded theory method comprising of systematic, inductive and comparative approaches for conducting inquiry for the purpose of constructing theory (Bryant & Charmaz 2007: 1) the research found that people have experienced change at different levels. This information, triangulated against previous research, validated the claims that child sponsorship at an NGO level indeed has benefits for the children involved in their programs. Therefore this evaluation paper draws the conclusion through similarities found and qualitative personal views that the St. Mary’s Development and Care Centre has indeed had an impact on the Grahamstown community.
- Full Text:
- Date Issued: 2014
A study of the reintegration of female former child soldiers in Gulu District, northern Uganda
- Authors: Bertelsen, Anna
- Date: 2014
- Subjects: Women soldiers -- Uganda -- Gulu District , Child soldiers -- Uganda -- Gulu District , Patriarchy -- Uganda -- Gulu District
- Language: English
- Type: Thesis , Masters , MPhil
- Identifier: vital:8324 , http://hdl.handle.net/10948/d1020192
- Description: This research explores the perceptions and experiences of female former child soldiers in regard to their reintegration within the community of Gulu District, northern Uganda. In many societies women are generally excluded due to prevailing patriarchal hegemonies, with northern Uganda being no exception. Moreover, former child soldiers are commonly marginalized and discriminated against because members of communities commonly believe that they should be punished for the perceived atrocities that they allegedly committed during times of conflict, rather than be reintegrated into society. In this regard female former child soldiers can be identified as a particularly vulnerable and marginalized group. Therefore, it can be suggested that although the distinction between traditional gender roles has been eroded during times of armed conflict, there is still widespread evidence that women are largely overlooked and disregarded in the process of peace building. In order to explore the perceptions and experiences of former female child soldiers, a qualitative case study method was utilized based on in-depth face to face interviews with women from Gulu District, northern Uganda. The findings of this study indicate that, even though these women went through considerable hardships, all of them displayed a strong sense of resilience. Many of them had taken on the role as active change agents in their own lives and provided an array of suggestions on how their situation could be improved. The major themes constructed from the study include: challenges facing returnees; facilitating factors for returnees and suggestions on improved reintegration. Based on these findings a number of recommendations emerged. The recommendations are presented in order to assist organizations and other stakeholders involved in reintegration of child soldiers in northern Uganda and elsewhere in the world. Apart from providing information to the existing body of research, future areas of proposed research are also outlined.
- Full Text:
- Date Issued: 2014
- Authors: Bertelsen, Anna
- Date: 2014
- Subjects: Women soldiers -- Uganda -- Gulu District , Child soldiers -- Uganda -- Gulu District , Patriarchy -- Uganda -- Gulu District
- Language: English
- Type: Thesis , Masters , MPhil
- Identifier: vital:8324 , http://hdl.handle.net/10948/d1020192
- Description: This research explores the perceptions and experiences of female former child soldiers in regard to their reintegration within the community of Gulu District, northern Uganda. In many societies women are generally excluded due to prevailing patriarchal hegemonies, with northern Uganda being no exception. Moreover, former child soldiers are commonly marginalized and discriminated against because members of communities commonly believe that they should be punished for the perceived atrocities that they allegedly committed during times of conflict, rather than be reintegrated into society. In this regard female former child soldiers can be identified as a particularly vulnerable and marginalized group. Therefore, it can be suggested that although the distinction between traditional gender roles has been eroded during times of armed conflict, there is still widespread evidence that women are largely overlooked and disregarded in the process of peace building. In order to explore the perceptions and experiences of former female child soldiers, a qualitative case study method was utilized based on in-depth face to face interviews with women from Gulu District, northern Uganda. The findings of this study indicate that, even though these women went through considerable hardships, all of them displayed a strong sense of resilience. Many of them had taken on the role as active change agents in their own lives and provided an array of suggestions on how their situation could be improved. The major themes constructed from the study include: challenges facing returnees; facilitating factors for returnees and suggestions on improved reintegration. Based on these findings a number of recommendations emerged. The recommendations are presented in order to assist organizations and other stakeholders involved in reintegration of child soldiers in northern Uganda and elsewhere in the world. Apart from providing information to the existing body of research, future areas of proposed research are also outlined.
- Full Text:
- Date Issued: 2014
A study on the application technology of the sterile insect technique, with focus on false codling moth, Thaumatotibia leucotreta (Meyrick) (Lepidoptera: Tortricidae), a pest of citrus in South Africa
- Authors: Nepgen, Eugene Stephan
- Date: 2014
- Subjects: Cryptophlebia leucotreta , Citrus -- Diseases and pests -- Control -- South Africa , Insect pests -- Control -- South Africa , Insect sterilization
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5879 , http://hdl.handle.net/10962/d1013199
- Description: False codling moth (FCM), Thaumatotibia leucotreta (Meyrick) (Lepidoptera: Tortricidae) is considered the most important indigenous pest of citrus in southern Africa. Major concerns such as progressive insecticidal resistance, the negative impact of insecticides on the environment, as well as the influence of consumers opposed to chemical residues on fruit, created opportunities for biological control methods such as Sterile Insect Technology (SIT). This technology is now established in the Western and Eastern Cape provinces of South Africa as an effective, sustainable alternative to conventional FCM control methods. Due to the prevalence of the pest in all citrus producing areas of South Africa, potential for SIT to expand is enormous. Success of an SIT programme is highly dependent on efficient application of the technology to achieve its objectives in a timeous manner. The aim of this study was to advance the application of SIT for control of FCM on citrus in South Africa, by investigating the effect of certain critical stages in the process. The effect of long-distance transportation on fitness of irradiated FCM was determined, showing reduced performance with cold-immobilized transport. A significant decrease in flight ability and longevity of irradiated FCM was found, although critically, realized fecundity was not affected. The effect of two different insecticides in the pyrethroid and organophosphate chemical groups were investigated for their residual effect on mortality of released irradiated FCM, to determine if these pest control programmes could be integrated. Both chlorpyrifos and tau-fluvalinate were effective in killing irradiated FCM for a number of days after application, after which degradation of the active ingredient rendered it harmless. This effect was found to be similar for irradiated and non-irradiated males, consequently ratios of sterile : wild male FCM should be retained regardless of whether sprays are applied or not. The modes for release of sterile FCM in an SIT programme were investigated. Efficacy of ground and aerial release platforms were tested by evaluating the recovery of released irradiated male FCM in these orchards. More irradiated FCM were recovered in orchards released from the ground compared to air. However, an economic analysis of both methods shows application of irradiated insects over a large geographical area is more cost-effective by air. Depending on the terrain and size of the target area, a combination of both methods is ideal for application of SIT for control of FCM in citrus. Development of application technology for advance of the programme is discussed and recommendations for future research and development are offered.
- Full Text:
- Date Issued: 2014
- Authors: Nepgen, Eugene Stephan
- Date: 2014
- Subjects: Cryptophlebia leucotreta , Citrus -- Diseases and pests -- Control -- South Africa , Insect pests -- Control -- South Africa , Insect sterilization
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:5879 , http://hdl.handle.net/10962/d1013199
- Description: False codling moth (FCM), Thaumatotibia leucotreta (Meyrick) (Lepidoptera: Tortricidae) is considered the most important indigenous pest of citrus in southern Africa. Major concerns such as progressive insecticidal resistance, the negative impact of insecticides on the environment, as well as the influence of consumers opposed to chemical residues on fruit, created opportunities for biological control methods such as Sterile Insect Technology (SIT). This technology is now established in the Western and Eastern Cape provinces of South Africa as an effective, sustainable alternative to conventional FCM control methods. Due to the prevalence of the pest in all citrus producing areas of South Africa, potential for SIT to expand is enormous. Success of an SIT programme is highly dependent on efficient application of the technology to achieve its objectives in a timeous manner. The aim of this study was to advance the application of SIT for control of FCM on citrus in South Africa, by investigating the effect of certain critical stages in the process. The effect of long-distance transportation on fitness of irradiated FCM was determined, showing reduced performance with cold-immobilized transport. A significant decrease in flight ability and longevity of irradiated FCM was found, although critically, realized fecundity was not affected. The effect of two different insecticides in the pyrethroid and organophosphate chemical groups were investigated for their residual effect on mortality of released irradiated FCM, to determine if these pest control programmes could be integrated. Both chlorpyrifos and tau-fluvalinate were effective in killing irradiated FCM for a number of days after application, after which degradation of the active ingredient rendered it harmless. This effect was found to be similar for irradiated and non-irradiated males, consequently ratios of sterile : wild male FCM should be retained regardless of whether sprays are applied or not. The modes for release of sterile FCM in an SIT programme were investigated. Efficacy of ground and aerial release platforms were tested by evaluating the recovery of released irradiated male FCM in these orchards. More irradiated FCM were recovered in orchards released from the ground compared to air. However, an economic analysis of both methods shows application of irradiated insects over a large geographical area is more cost-effective by air. Depending on the terrain and size of the target area, a combination of both methods is ideal for application of SIT for control of FCM in citrus. Development of application technology for advance of the programme is discussed and recommendations for future research and development are offered.
- Full Text:
- Date Issued: 2014
A survey of youth development projects in the Department of Social Development in the province of the Eastern Cape: a management perspective
- Dliwayo, Mziwodumo Archibald
- Authors: Dliwayo, Mziwodumo Archibald
- Date: 2014
- Subjects: Youth in development -- South Africa -- Eastern Cape , Economic development projects , Youth -- Services for
- Language: English
- Type: Thesis , Masters , MPA
- Identifier: http://hdl.handle.net/10948/4429 , vital:20600
- Description: The objective of this research is to establish how non-adherence of Amathole District development projects to the Department of Social Development’s Community Development Systems and Operational Manual has contributed to failure of these projects. The background to this research lies in the deliberate policy efforts of the post 1994 democratic dispensation in South Africa to drive development through community-based development approaches. Explicitly pro-poor public policies, development plans and fiscal frameworks were anchored on the concept of community empowerment. The Reconstruction and Development Programme was the first such policy and strategy framework that sought to enshrine the principles of community empowerment and participation. As such, Provincial and Local government are often seen as key strategic drivers of community empowerment initiatives and interventions. South Africa’s governance model is still evolving, but it is clearly committed to local development and service delivery through a decentralised system of government that espouses community involvement. Government strategy has been heavily focused on speed and delivery in order to deal with the historical socio-economic backlogs it inherited. In the focus area of youth development projects, one recognises that poor management has dramatically reduced the effectiveness of many interventions. This research explores how non-adherence of these projects to policy guidelines set out in the Community Development Systems and Operations Manual has contributed to their failure. The research does this by looking at the various management procedures that are supposed to be undertaken during both the initial planning phases and during the subsequent implementation phases of youth development projects. Actual methodologies are compared against this standard. The research is undoubtedly a contribution to the field of strategic management of youth development initiatives which have as their primary intention the reduction of youth unemployment. Research surveys on this topic are limited, and the objective is to enrich the discourse on effective youth projects management practices.
- Full Text:
- Date Issued: 2014
- Authors: Dliwayo, Mziwodumo Archibald
- Date: 2014
- Subjects: Youth in development -- South Africa -- Eastern Cape , Economic development projects , Youth -- Services for
- Language: English
- Type: Thesis , Masters , MPA
- Identifier: http://hdl.handle.net/10948/4429 , vital:20600
- Description: The objective of this research is to establish how non-adherence of Amathole District development projects to the Department of Social Development’s Community Development Systems and Operational Manual has contributed to failure of these projects. The background to this research lies in the deliberate policy efforts of the post 1994 democratic dispensation in South Africa to drive development through community-based development approaches. Explicitly pro-poor public policies, development plans and fiscal frameworks were anchored on the concept of community empowerment. The Reconstruction and Development Programme was the first such policy and strategy framework that sought to enshrine the principles of community empowerment and participation. As such, Provincial and Local government are often seen as key strategic drivers of community empowerment initiatives and interventions. South Africa’s governance model is still evolving, but it is clearly committed to local development and service delivery through a decentralised system of government that espouses community involvement. Government strategy has been heavily focused on speed and delivery in order to deal with the historical socio-economic backlogs it inherited. In the focus area of youth development projects, one recognises that poor management has dramatically reduced the effectiveness of many interventions. This research explores how non-adherence of these projects to policy guidelines set out in the Community Development Systems and Operations Manual has contributed to their failure. The research does this by looking at the various management procedures that are supposed to be undertaken during both the initial planning phases and during the subsequent implementation phases of youth development projects. Actual methodologies are compared against this standard. The research is undoubtedly a contribution to the field of strategic management of youth development initiatives which have as their primary intention the reduction of youth unemployment. Research surveys on this topic are limited, and the objective is to enrich the discourse on effective youth projects management practices.
- Full Text:
- Date Issued: 2014
A sustainability reporting framework for South African Higher Education Institutions
- Authors: Bosire, Samuel Mobisa
- Date: 2014
- Subjects: Sustainable development reporting -- South Africa , Business intelligence -- South Africa , Universities and colleges -- South Africa , Corporate governance -- South Africa
- Language: English
- Type: Thesis , Doctoral , DBA
- Identifier: vital:8798 , http://hdl.handle.net/10948/d1016126
- Description: Sustainability has gained prominence globally among nations, regions and organisations as a result of factors such as the effects of climate change on the environment, diminishing natural resources and rising population growth with their concomitant impact on economies and social systems. South Africa is a signatory to the United Nations Global Compact (UNGC) that promotes international principles and best practices on sustainable development. Sustainability Reporting is one such best practice. Sustainability Reporting is imperative for good governance and organisations are now expected to support sustainability issues, risks and performance in a balanced and reasonable way. The United Nations and other global bodies have been in the vanguard in promoting guidelines for sustainability reporting with the Global Reporting Initiative (GRI) being the most Prominent Sustainability reporting guideline. The South African Higher Education Institutions generate a number of reports in the course of any given academic year. As has been the case in the global corporate world, failures in governance in some South African universities point to weaknesses in their governance, especially when it comes to oversight of the operations of institutions. Considering this, it is important to critically examine strategic planning processes to understand the aspects that are important for the survival of Higher Education Institutions (HEIs) and therefore they should be regularly and closely monitored. The study begins by exploring literature relating to strategic planning, governance, sustainability reporting practices and Business Intelligence (BI) technologies in Higher Education. The primary objective of the investigation is to propose a sustainability reporting framework for Higher Education Institutions in South Africa. It is argued that with the aid of appropriate BI tools, the proposed Sustainability Reporting framework would be useful in tracking progress in the implementation of strategic plans and at the same time strengthen governance in institutions. The study identified elements of Sustainability Reporting that are important for strategic planning. To develop the proposed framework, an empirical investigation was undertaken. Four online questionnaires were completed and returned by 108 participants comprising of Registrars and Information Managers at 23 South African Higher Education Institutions as well as to Information Managers in selected International Higher Education Institutions and Managers at the Nelson Mandela Metropolitan University (NMMU). The online questionnaires were developed to elicit information to include in the proposed framework. To analyse results, both descriptive and inferential statistics such as Analysis of Variance (ANOVA) were used. Results from the surveys revealed that Higher Education Institutions globally and in South Africa are grappling with the same issues. When it comes to Sustainability Reporting, factors such as information culture and Business Intelligence maturity levels were not found to be very different among the various institutions. In the case study at NMMU, correlational analysis confirmed that variables such as Management buying and the availability of BI reports were positively related to effective strategic planning and vice versa. Similarly, a strong correlation was observed between reporting guidelines and strategic planning. Moreover, the study highlighted the critical role of management and leadership in a university in creating an environment that supports Sustainability Reporting. In conclusion, it was recommended that efforts should be directed at creating awareness and at training staff on aspects that promote sustainability. It is incumbent upon the institution to take advantage of and promote technological tools and techniques to enable the easy flow of data and information in understandable and usable formats to all its stakeholders. Finally, a Framework for Sustainability Reporting for Higher Education Institutions (FSRHEI) and guidelines for implementing Sustainability Reports are proposed.
- Full Text:
- Date Issued: 2014
- Authors: Bosire, Samuel Mobisa
- Date: 2014
- Subjects: Sustainable development reporting -- South Africa , Business intelligence -- South Africa , Universities and colleges -- South Africa , Corporate governance -- South Africa
- Language: English
- Type: Thesis , Doctoral , DBA
- Identifier: vital:8798 , http://hdl.handle.net/10948/d1016126
- Description: Sustainability has gained prominence globally among nations, regions and organisations as a result of factors such as the effects of climate change on the environment, diminishing natural resources and rising population growth with their concomitant impact on economies and social systems. South Africa is a signatory to the United Nations Global Compact (UNGC) that promotes international principles and best practices on sustainable development. Sustainability Reporting is one such best practice. Sustainability Reporting is imperative for good governance and organisations are now expected to support sustainability issues, risks and performance in a balanced and reasonable way. The United Nations and other global bodies have been in the vanguard in promoting guidelines for sustainability reporting with the Global Reporting Initiative (GRI) being the most Prominent Sustainability reporting guideline. The South African Higher Education Institutions generate a number of reports in the course of any given academic year. As has been the case in the global corporate world, failures in governance in some South African universities point to weaknesses in their governance, especially when it comes to oversight of the operations of institutions. Considering this, it is important to critically examine strategic planning processes to understand the aspects that are important for the survival of Higher Education Institutions (HEIs) and therefore they should be regularly and closely monitored. The study begins by exploring literature relating to strategic planning, governance, sustainability reporting practices and Business Intelligence (BI) technologies in Higher Education. The primary objective of the investigation is to propose a sustainability reporting framework for Higher Education Institutions in South Africa. It is argued that with the aid of appropriate BI tools, the proposed Sustainability Reporting framework would be useful in tracking progress in the implementation of strategic plans and at the same time strengthen governance in institutions. The study identified elements of Sustainability Reporting that are important for strategic planning. To develop the proposed framework, an empirical investigation was undertaken. Four online questionnaires were completed and returned by 108 participants comprising of Registrars and Information Managers at 23 South African Higher Education Institutions as well as to Information Managers in selected International Higher Education Institutions and Managers at the Nelson Mandela Metropolitan University (NMMU). The online questionnaires were developed to elicit information to include in the proposed framework. To analyse results, both descriptive and inferential statistics such as Analysis of Variance (ANOVA) were used. Results from the surveys revealed that Higher Education Institutions globally and in South Africa are grappling with the same issues. When it comes to Sustainability Reporting, factors such as information culture and Business Intelligence maturity levels were not found to be very different among the various institutions. In the case study at NMMU, correlational analysis confirmed that variables such as Management buying and the availability of BI reports were positively related to effective strategic planning and vice versa. Similarly, a strong correlation was observed between reporting guidelines and strategic planning. Moreover, the study highlighted the critical role of management and leadership in a university in creating an environment that supports Sustainability Reporting. In conclusion, it was recommended that efforts should be directed at creating awareness and at training staff on aspects that promote sustainability. It is incumbent upon the institution to take advantage of and promote technological tools and techniques to enable the easy flow of data and information in understandable and usable formats to all its stakeholders. Finally, a Framework for Sustainability Reporting for Higher Education Institutions (FSRHEI) and guidelines for implementing Sustainability Reports are proposed.
- Full Text:
- Date Issued: 2014
A systematic review of the effectiveness of animal-assisted interventions
- Authors: Badenhorst, Estelle
- Date: 2014
- Subjects: Animals -- Therapeutic use , Human-animal relationships
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9980 , http://hdl.handle.net/10948/d1021139
- Description: There is a global increase in research on the benefits of animals and the value of incorporating them into interventional practices. This is referred to as animal-assisted interventions. Due to the novelty of this type of intervention and the accompanying complexity of variables, a need exists to explore the various aspects within these interventions. Looking specifically at animal-assisted interventions within the mental health field, this study focuses on the psycho-therapeutic value of companion animals, such as dogs and cats. The primary aim of this study was to identify the mechanisms through which an animal-assisted intervention exerts its influence. A secondary aim was to indentify salient methodological aspects within the included studies. A systematic review of existing literature was undertaken to explore these factors. Each study was appraised against specific inclusion and exclusion criteria and themes were extracted. The data was synthesised, integrated and discussed in relation to previously conducted studies in relevant fields. Six themes emerged from the systematic review. These included enhanced comfort, the living nature of animals, physical contact, adjunctive nature, an affinity for animals, as well as methodological considerations. Based on these emergent themes conclusions were drawn as to the psycho-therapeutic influences of companion animals. This may serve as informative knowledge regarding animal-assisted interventions for practitioners seeking additional methods to reach treatment goals. Information is also provided for researchers interested in the field, particularly methodological considerations, before embarking on a study of animal-assisted intervention efficacy.
- Full Text:
- Date Issued: 2014
- Authors: Badenhorst, Estelle
- Date: 2014
- Subjects: Animals -- Therapeutic use , Human-animal relationships
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9980 , http://hdl.handle.net/10948/d1021139
- Description: There is a global increase in research on the benefits of animals and the value of incorporating them into interventional practices. This is referred to as animal-assisted interventions. Due to the novelty of this type of intervention and the accompanying complexity of variables, a need exists to explore the various aspects within these interventions. Looking specifically at animal-assisted interventions within the mental health field, this study focuses on the psycho-therapeutic value of companion animals, such as dogs and cats. The primary aim of this study was to identify the mechanisms through which an animal-assisted intervention exerts its influence. A secondary aim was to indentify salient methodological aspects within the included studies. A systematic review of existing literature was undertaken to explore these factors. Each study was appraised against specific inclusion and exclusion criteria and themes were extracted. The data was synthesised, integrated and discussed in relation to previously conducted studies in relevant fields. Six themes emerged from the systematic review. These included enhanced comfort, the living nature of animals, physical contact, adjunctive nature, an affinity for animals, as well as methodological considerations. Based on these emergent themes conclusions were drawn as to the psycho-therapeutic influences of companion animals. This may serve as informative knowledge regarding animal-assisted interventions for practitioners seeking additional methods to reach treatment goals. Information is also provided for researchers interested in the field, particularly methodological considerations, before embarking on a study of animal-assisted intervention efficacy.
- Full Text:
- Date Issued: 2014
A teaching case study on the effect of growth on organisational leadership and culture at hardware warehouse as the organisation grew from one store to 18 stores
- Authors: Mfabane, Masiwakhe
- Date: 2014
- Subjects: Corporate culture -- South Africa -- Case studies , Leadership -- South Africa -- Case studies , Management -- South Africa -- Case studies , Hardware stores -- South Africa -- Management
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:829 , http://hdl.handle.net/10962/d1013008
- Description: From summary:The main objective of this research study was to write up a teaching case study, based on Greiner’s (1998) model of organisational development, outlining what effect the growth of Hardware Warehouse had on the leadership and culture of the organisation. The study is a teaching case study in the form of “a descriptive case focusing on presenting a description of past events and decisions” (Cappel and Schwager, 2002: 289).
- Full Text:
- Date Issued: 2014
- Authors: Mfabane, Masiwakhe
- Date: 2014
- Subjects: Corporate culture -- South Africa -- Case studies , Leadership -- South Africa -- Case studies , Management -- South Africa -- Case studies , Hardware stores -- South Africa -- Management
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:829 , http://hdl.handle.net/10962/d1013008
- Description: From summary:The main objective of this research study was to write up a teaching case study, based on Greiner’s (1998) model of organisational development, outlining what effect the growth of Hardware Warehouse had on the leadership and culture of the organisation. The study is a teaching case study in the form of “a descriptive case focusing on presenting a description of past events and decisions” (Cappel and Schwager, 2002: 289).
- Full Text:
- Date Issued: 2014
A temporal dimension to the influence of pollen rewards on bee behaviour and fecundity in Aloe tenuior
- Duffy, Karl J, Johnson, Steven D, Peter, Craig I
- Authors: Duffy, Karl J , Johnson, Steven D , Peter, Craig I
- Date: 2014
- Language: English
- Type: Article
- Identifier: vital:6561 , http://hdl.handle.net/10962/d1011735 , http://dx.doi.org/10.1371/journal.pone.0094908
- Description: The net effect of pollen production on fecundity in plants can range from negative – when self-pollen interferes with fecundity due to incompatibility mechanisms, to positive – when pollen availability is associated with increased pollinator visitation and fecundity due to its utilization as a reward. We investigated the responses of bees to pollen and nectar rewards, and the effects of these rewards on pollen deposition and fecundity in the hermaphroditic succulent shrub Aloe tenuior. Self-pollinated plants failed to set fruit, but their ovules were regularly penetrated by self-pollen tubes, which uniformly failed to develop into seeds as expected from ovarian self-incompatibility (or strong early inbreeding depression). Bees consistently foraged for pollen during the morning and early afternoon, but switched to nectar in the late afternoon. As a consequence of this differential foraging, we were able to test the relative contribution to fecundity of pollen- versus nectar-collecting flower visitors. We exposed emasculated and intact flowers in either the morning or late afternoon to foraging bees and showed that emasculation reduced pollen deposition by insects in the morning, but had little effect in the afternoon. Despite the potential for self-pollination to result in ovule discounting due to late-acting self-sterility, fecundity was severely reduced in artificially emasculated plants. Although there were temporal fluctuations in reward preference, most bee visits were for pollen rewards. Therefore the benefit of providing pollen that is accessible to bee foragers outweighs any potential costs to fitness in terms of gender interference in this species.
- Full Text:
- Date Issued: 2014
- Authors: Duffy, Karl J , Johnson, Steven D , Peter, Craig I
- Date: 2014
- Language: English
- Type: Article
- Identifier: vital:6561 , http://hdl.handle.net/10962/d1011735 , http://dx.doi.org/10.1371/journal.pone.0094908
- Description: The net effect of pollen production on fecundity in plants can range from negative – when self-pollen interferes with fecundity due to incompatibility mechanisms, to positive – when pollen availability is associated with increased pollinator visitation and fecundity due to its utilization as a reward. We investigated the responses of bees to pollen and nectar rewards, and the effects of these rewards on pollen deposition and fecundity in the hermaphroditic succulent shrub Aloe tenuior. Self-pollinated plants failed to set fruit, but their ovules were regularly penetrated by self-pollen tubes, which uniformly failed to develop into seeds as expected from ovarian self-incompatibility (or strong early inbreeding depression). Bees consistently foraged for pollen during the morning and early afternoon, but switched to nectar in the late afternoon. As a consequence of this differential foraging, we were able to test the relative contribution to fecundity of pollen- versus nectar-collecting flower visitors. We exposed emasculated and intact flowers in either the morning or late afternoon to foraging bees and showed that emasculation reduced pollen deposition by insects in the morning, but had little effect in the afternoon. Despite the potential for self-pollination to result in ovule discounting due to late-acting self-sterility, fecundity was severely reduced in artificially emasculated plants. Although there were temporal fluctuations in reward preference, most bee visits were for pollen rewards. Therefore the benefit of providing pollen that is accessible to bee foragers outweighs any potential costs to fitness in terms of gender interference in this species.
- Full Text:
- Date Issued: 2014
A virtual-community-centric model for coordination in the South African public sector
- Thomas, Godwin Dogara Ayenajeh
- Authors: Thomas, Godwin Dogara Ayenajeh
- Date: 2014
- Subjects: Electronic data processing -- Distributed processing , Interprofessional relations , Virtual work teams
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: vital:9831 , http://hdl.handle.net/10948/d1021073
- Description: Organizations face challenges constantly owing to limited resources. As such, to take advantage of new opportunities and to mitigate possible risks they look for new ways to collaborate, by sharing knowledge and competencies. Coordination among partners is critical in order to achieve success. The segmented South African public sector is no different. Driven by the desire to ensure proper service delivery in this sector, various government bodies and service providers play different roles towards the attainment of common goals. This is easier said than done, given the complexity of the distributed nature of the environment. Heterogeneity, autonomy, and the increasing need to collaborate provoke the need to develop an integrative and dynamic coordination support service system in the SA public sector. Thus, the research looks to theories/concepts and existing coordination practices to ground the process of development. To inform the design of the proposed artefact the research employs an interdisciplinary approach championed by coordination theory to review coordination-related theories and concepts. The effort accounts for coordination constructs that characterize and transform the problem and solution spaces. Thus, requirements are explicit towards identifying coordination breakdowns and their resolution. Furthermore, how coordination in a distributed environment is supported in practice is considered from a socio-technical perspective in an effort to account holistically for coordination support. Examining existing solutions identified shortcomings that, if addressed, can help to improve the solutions for coordination, which are often rigidly and narrowly defined. The research argues that introducing a mediating technological artefact conceived from a virtual community and service lenses can serve as a solution to the problem. By adopting a design-science research paradigm, the research develops a model as a primary artefact to support coordination from a collaboration standpoint. The suggestions from theory and practice and the unique case requirement identified through a novel case analysis framework form the basis of the model design. The proposed model support operation calls for an architecture which employs a design pattern that divides a complex whole into smaller, simpler parts, with the aim of reducing the system complexity. Four fundamental functions of the supporting architecture are introduced and discussed as they would support the operation and activities of the proposed collaboration lifecycle model geared towards streamlining coordination in a distributed environment. As part of the model development knowledge contributions are made in several ways. Firstly, an analytical instrument is presented that can be used by an enterprise architect or business analyst to study the coordination status quo of a collaborative activity in a distributed environment. Secondly, a lifecycle model is presented as meta-process model with activities that are geared towards streamlining the coordination of dynamic collaborative activities or projects. Thirdly, an architecture that will enable the technical virtual community-centric, context-aware environment that hosts the process-based operations is offered. Finally, the validation tool that represents the applied contribution to the research that promises possible adaptation for similar circumstances is presented. The artefacts contribute towards a design theory in IS research for the development and improvement of coordination support services in a distributed environment such as the South African public sector.
- Full Text:
- Date Issued: 2014
- Authors: Thomas, Godwin Dogara Ayenajeh
- Date: 2014
- Subjects: Electronic data processing -- Distributed processing , Interprofessional relations , Virtual work teams
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: vital:9831 , http://hdl.handle.net/10948/d1021073
- Description: Organizations face challenges constantly owing to limited resources. As such, to take advantage of new opportunities and to mitigate possible risks they look for new ways to collaborate, by sharing knowledge and competencies. Coordination among partners is critical in order to achieve success. The segmented South African public sector is no different. Driven by the desire to ensure proper service delivery in this sector, various government bodies and service providers play different roles towards the attainment of common goals. This is easier said than done, given the complexity of the distributed nature of the environment. Heterogeneity, autonomy, and the increasing need to collaborate provoke the need to develop an integrative and dynamic coordination support service system in the SA public sector. Thus, the research looks to theories/concepts and existing coordination practices to ground the process of development. To inform the design of the proposed artefact the research employs an interdisciplinary approach championed by coordination theory to review coordination-related theories and concepts. The effort accounts for coordination constructs that characterize and transform the problem and solution spaces. Thus, requirements are explicit towards identifying coordination breakdowns and their resolution. Furthermore, how coordination in a distributed environment is supported in practice is considered from a socio-technical perspective in an effort to account holistically for coordination support. Examining existing solutions identified shortcomings that, if addressed, can help to improve the solutions for coordination, which are often rigidly and narrowly defined. The research argues that introducing a mediating technological artefact conceived from a virtual community and service lenses can serve as a solution to the problem. By adopting a design-science research paradigm, the research develops a model as a primary artefact to support coordination from a collaboration standpoint. The suggestions from theory and practice and the unique case requirement identified through a novel case analysis framework form the basis of the model design. The proposed model support operation calls for an architecture which employs a design pattern that divides a complex whole into smaller, simpler parts, with the aim of reducing the system complexity. Four fundamental functions of the supporting architecture are introduced and discussed as they would support the operation and activities of the proposed collaboration lifecycle model geared towards streamlining coordination in a distributed environment. As part of the model development knowledge contributions are made in several ways. Firstly, an analytical instrument is presented that can be used by an enterprise architect or business analyst to study the coordination status quo of a collaborative activity in a distributed environment. Secondly, a lifecycle model is presented as meta-process model with activities that are geared towards streamlining the coordination of dynamic collaborative activities or projects. Thirdly, an architecture that will enable the technical virtual community-centric, context-aware environment that hosts the process-based operations is offered. Finally, the validation tool that represents the applied contribution to the research that promises possible adaptation for similar circumstances is presented. The artefacts contribute towards a design theory in IS research for the development and improvement of coordination support services in a distributed environment such as the South African public sector.
- Full Text:
- Date Issued: 2014
Academic development as enhancement: celebrating a decade of the TLC through the annual teaching week
- Jonas, N, Schekle, L, Toni, N
- Authors: Jonas, N , Schekle, L , Toni, N
- Date: 2014
- Language: English
- Type: Newsletter
- Identifier: vital:12226 , http://hdl.handle.net/10353/d1016144
- Description: Teaching and Learning Centre newsletter 2014 first edition
- Full Text: false
- Date Issued: 2014
- Authors: Jonas, N , Schekle, L , Toni, N
- Date: 2014
- Language: English
- Type: Newsletter
- Identifier: vital:12226 , http://hdl.handle.net/10353/d1016144
- Description: Teaching and Learning Centre newsletter 2014 first edition
- Full Text: false
- Date Issued: 2014
Accounting student's success factors: an exploratory investigation
- Authors: Stack, Elizabeth M
- Date: 2014
- Subjects: To be catalogued
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/2134 , vital:20258
- Description: This presentation is aimed at identifying possible success factors leading to the success of students studying accounting, as well as to hightlight some of the problems they may face.
- Full Text:
- Date Issued: 2014
- Authors: Stack, Elizabeth M
- Date: 2014
- Subjects: To be catalogued
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/2134 , vital:20258
- Description: This presentation is aimed at identifying possible success factors leading to the success of students studying accounting, as well as to hightlight some of the problems they may face.
- Full Text:
- Date Issued: 2014
Activated carbon from lignocellulosic waste residues: effect of activating agent on porosity characteristics and use as adsorbents for organic species
- Olorundare, O F, Okonkwo, J O, Msagati, T A M, Mamba, Bhekie B, Krause, Rui W M
- Authors: Olorundare, O F , Okonkwo, J O , Msagati, T A M , Mamba, Bhekie B , Krause, Rui W M
- Date: 2014
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/125233 , vital:35748 , https://doi.org/10.1007/s11270-014-1876-2
- Description: This paper reports on the effect of activating agents such as the impregnation ratio of phosphoric acid (1:1–1:5) at constant activation temperature on the performance of porous activated carbon from waste residues (maize tassel). The variation in the impregnation ratio of the produced activated carbon (AC) from 1:1 to 1:5 enabled the preparation of a high surface area (1,263 m2/g) and a large pore volume (1.592 cm3/g) of AC produced from maize tassel (MT) using a convectional chemical activating agent (phosphoric acid). Impregnation ratios (IR) of the precursors were varied between 1:1 and 1:5 in which it was found that the ratio of 1:4 was optimal based on the high surface area, while 1:5 has the optimal pore volume value for the produced activated carbon.
- Full Text:
- Date Issued: 2014
- Authors: Olorundare, O F , Okonkwo, J O , Msagati, T A M , Mamba, Bhekie B , Krause, Rui W M
- Date: 2014
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/125233 , vital:35748 , https://doi.org/10.1007/s11270-014-1876-2
- Description: This paper reports on the effect of activating agents such as the impregnation ratio of phosphoric acid (1:1–1:5) at constant activation temperature on the performance of porous activated carbon from waste residues (maize tassel). The variation in the impregnation ratio of the produced activated carbon (AC) from 1:1 to 1:5 enabled the preparation of a high surface area (1,263 m2/g) and a large pore volume (1.592 cm3/g) of AC produced from maize tassel (MT) using a convectional chemical activating agent (phosphoric acid). Impregnation ratios (IR) of the precursors were varied between 1:1 and 1:5 in which it was found that the ratio of 1:4 was optimal based on the high surface area, while 1:5 has the optimal pore volume value for the produced activated carbon.
- Full Text:
- Date Issued: 2014
Adherence to antiretroviral therapy in children in Zimbabwe: a randomized control trial to validate a new self-reported adherence monitoring tool
- Authors: Mugore, Linnetie
- Date: 2014
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/54734 , vital:26607
- Description: Background: Among children taking antiretroviral therapy (ART), self-reports have been widely reported to over-estimate adherence levels. Pill count adherence levels are often lower than self-reported levels, with unannounced home pill count adherence being lower than facility based pill count adherence. There is often poor agreement between pill count adherence levels and those measured using other objective adherence measuring methods such as Medication Event Monitoring Systems (MEMS®), which is widely viewed as the gold standard for adherence measurement. Objectives: The aim of this study was to design and evaluate a new self-reported paediatric adherence monitoring tool, assess the feasibility of using pill count methods in monitoring adherence and identify challenges to reporting adherence among children on ART in rural and urban Zimbabwe. Methods A dual centre, superiority, parallel design RCT was conducted to evaluate the newly-developed visually- and verbally-cued „past 10 days‟ tool for the assessment of adherence in children on ART at two sites in Zimbabwe; Harare Central Children‟s Hospital in an urban setting, and Murambinda Mission Hospital, a rural site. Child-caregiver pairs presenting to one of these facilities for the child‟s review of ART and refill of the medication were recruited, signed informed consent obtained, and were randomised for self-reported adherence monitoring into either the experimental group („new 10-day tool‟) or the control group („PACTG-style‟ self-report tool). Data (demographic, socioeconomic, and reported adherence) were collected in individual interviews with child-caregiver pairs. Additional adherence monitoring methods used for both groups included the Morisky-8-Item Medication Adherence Scale (MMAS-8) and a facility based pill count. FGDs were held with groups of caregivers and groups of children ≥13 years of age to understand reasons for non-adherence as well as issues around reporting non-adherence. Superiority testing was conducted by comparing adherent proportions and their confidence intervals (95% CI). Further concurrent validity test was done using the Mann-Whitney U test to evaluate the relationship between the new tool and the MMAS-8 scores. Agreement between the child and caregiver reports of adherence was used as a test of reliability of the new tool using the kappa statistic. Socio-demographic, clinical and care-related factors associated with adherence were identified using reported adherence in both child and caregiver groups in a logistic regression model. Two pill count methods were assessed for feasibility using the proportions of children with complete data for calculating adherence levels, and their CI and a comparison of the two methods, a routinely-used method and one that incorporated the reported residual quantity (RRQ) of medication at last refill. Results : Analysis included 245 child-caregiver pairs, 123 in the experimental group and 122 in the control group. The median age for children was 9 years. In the experimental group, adherence by caregiver and child reports ranged from 94.3% - 98.4% and 78.4% - 96.1%, and those in the control group ranged from 89.2% - 97.5% and 71.2% - 98.1%, respectively. There was no significant difference between adherence levels in the two groups. Adherence levels measured by both the experimental and control tools were found to be associated with MMAS-8 adherence levels (p <0.05). Agreement between child- and caregiver-reported adherence was moderate though significant (kappa; 0.407, p <0.05). Only about half of the children had adequate data to compute pill counts. Proportions adherent at 95% cut-off were 39% by the „routine pill count‟ and 58% by the „Pill count RRQ‟. Being an orphan was associated with child reported-adherence whereas use of non-human reminders, having a maternal relative as a primary caregiver and knowledge of dose frequency, were all associated with caregiver-reported adherence. Major causes of non-adherence mentioned during the FGDs included interference of medication administration times with scheduling of routine socio-economic activities and lack of support from some non-biological caregivers. Reporting of non-adherence appeared to be hampered by perceptions of negative reactions by healthcare workers to these reports and by caregivers being unaware that the child missed some doses. Conclusions: The „new 10-day tool‟ was not shown to be superior to the „PACTG-style tool‟ in detecting non-adherence, however this new tool was found to be a valid and reliable adherence monitoring tool that included a moderately long recall period of 10 days, can be applied without the need for the respondent to remember names of individual medicines in the
- Full Text:
- Date Issued: 2014
- Authors: Mugore, Linnetie
- Date: 2014
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/54734 , vital:26607
- Description: Background: Among children taking antiretroviral therapy (ART), self-reports have been widely reported to over-estimate adherence levels. Pill count adherence levels are often lower than self-reported levels, with unannounced home pill count adherence being lower than facility based pill count adherence. There is often poor agreement between pill count adherence levels and those measured using other objective adherence measuring methods such as Medication Event Monitoring Systems (MEMS®), which is widely viewed as the gold standard for adherence measurement. Objectives: The aim of this study was to design and evaluate a new self-reported paediatric adherence monitoring tool, assess the feasibility of using pill count methods in monitoring adherence and identify challenges to reporting adherence among children on ART in rural and urban Zimbabwe. Methods A dual centre, superiority, parallel design RCT was conducted to evaluate the newly-developed visually- and verbally-cued „past 10 days‟ tool for the assessment of adherence in children on ART at two sites in Zimbabwe; Harare Central Children‟s Hospital in an urban setting, and Murambinda Mission Hospital, a rural site. Child-caregiver pairs presenting to one of these facilities for the child‟s review of ART and refill of the medication were recruited, signed informed consent obtained, and were randomised for self-reported adherence monitoring into either the experimental group („new 10-day tool‟) or the control group („PACTG-style‟ self-report tool). Data (demographic, socioeconomic, and reported adherence) were collected in individual interviews with child-caregiver pairs. Additional adherence monitoring methods used for both groups included the Morisky-8-Item Medication Adherence Scale (MMAS-8) and a facility based pill count. FGDs were held with groups of caregivers and groups of children ≥13 years of age to understand reasons for non-adherence as well as issues around reporting non-adherence. Superiority testing was conducted by comparing adherent proportions and their confidence intervals (95% CI). Further concurrent validity test was done using the Mann-Whitney U test to evaluate the relationship between the new tool and the MMAS-8 scores. Agreement between the child and caregiver reports of adherence was used as a test of reliability of the new tool using the kappa statistic. Socio-demographic, clinical and care-related factors associated with adherence were identified using reported adherence in both child and caregiver groups in a logistic regression model. Two pill count methods were assessed for feasibility using the proportions of children with complete data for calculating adherence levels, and their CI and a comparison of the two methods, a routinely-used method and one that incorporated the reported residual quantity (RRQ) of medication at last refill. Results : Analysis included 245 child-caregiver pairs, 123 in the experimental group and 122 in the control group. The median age for children was 9 years. In the experimental group, adherence by caregiver and child reports ranged from 94.3% - 98.4% and 78.4% - 96.1%, and those in the control group ranged from 89.2% - 97.5% and 71.2% - 98.1%, respectively. There was no significant difference between adherence levels in the two groups. Adherence levels measured by both the experimental and control tools were found to be associated with MMAS-8 adherence levels (p <0.05). Agreement between child- and caregiver-reported adherence was moderate though significant (kappa; 0.407, p <0.05). Only about half of the children had adequate data to compute pill counts. Proportions adherent at 95% cut-off were 39% by the „routine pill count‟ and 58% by the „Pill count RRQ‟. Being an orphan was associated with child reported-adherence whereas use of non-human reminders, having a maternal relative as a primary caregiver and knowledge of dose frequency, were all associated with caregiver-reported adherence. Major causes of non-adherence mentioned during the FGDs included interference of medication administration times with scheduling of routine socio-economic activities and lack of support from some non-biological caregivers. Reporting of non-adherence appeared to be hampered by perceptions of negative reactions by healthcare workers to these reports and by caregivers being unaware that the child missed some doses. Conclusions: The „new 10-day tool‟ was not shown to be superior to the „PACTG-style tool‟ in detecting non-adherence, however this new tool was found to be a valid and reliable adherence monitoring tool that included a moderately long recall period of 10 days, can be applied without the need for the respondent to remember names of individual medicines in the
- Full Text:
- Date Issued: 2014