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Haigh, J M

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Date: 2003
Language: English
Type: text
Identifier: vital:6418
Description: Consumers of topical formulations apply a wide spectrum of preparations, both cosmetic and dermatological, to their healthy or diseased skin. These formulations range in physicochemical nature from so ... More
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Date: 2002
Language: English
Type: text
Identifier: vital:6427
Description: Topical corticosteroid formulations have been evaluated by visual grading protocols for many years. Toward a more objective methodology, several instrumental methods have been evaluated for applicabil ... More
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Authors: Haigh, J M | Smith, E W
Date: 2002
Language: English
Type: Article
Identifier: vital:6368
Description: [From the text]Topical corticosteroid formulations are used widely for a variety of skin conditions such as psoriasis and eczema. The most commonly used formulation types are cream, ointment, lotion a ... More
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Date: 2000
Language: English
Type: Book chapter
Identifier: vital:6451
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Date: 1999
Language: English
Type: text
Identifier: vital:6426
Description: In a Guidance document, the American FDA recommends the use of a Minolta chromameter rather than the human eye for the quantitative assessment of the pharmacodynamic blanching response produced by top ... More
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Date: 1999
Language: English
Type: text
Identifier: vital:6425
Description: Purpose. The thermodynamic acitvity of drugs in topical vehicles is considered to significantly influence topical delivery. In vitro diffusion across a synthetic membrane was shown to be correlated to ... More
Date: 1998
Language: English
Type: text
Identifier: vital:6424
Description: Purpose. One of the unresolved issues in the FDA Guidance document for topical corticosteroid bioequivalence testing is the method of manipulation suggested for the chromameter data. The purpose of th ... More
Date: 1998
Language: English
Type: Conference paper
Identifier: vital:6341
Description: Bioavailability concerns for topical dermatological products are complex and it is especially difficult to determine the bioequivalence of similar topical formulations. Since only small amounts of dru ... More
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Date: 1998
Language: English
Type: Article
Identifier: vital:6383
Description: Recently there has been some interest in the use of shed snake skin as a "model" membrane for in vitro diffusion studies. Many different species of snake have been utilised as well as different skin s ... More
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Date: 1998
Language: English
Type: Conference paper
Identifier: vital:6343
Description: Chromameters are compact portable instruments used for the assessment of surface colour based on the tristimulus analysis of a reflected xenon light pulse, and have been used for the quantification of ... More
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Date: 1998
Language: English
Type: Conference paper
Identifier: vital:6344
Description: In a recent Guidance document the American FDA recommended the use of a chromameterrather thanthe human eye for the assessment of the pharmacodynamic blanching response produced after topical applicat ... More
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Date: 1998
Language: English
Type: text
Identifier: vital:6423
Description: Reply to: Letter to the Editor by Singh GJ; Fleischer N; Lesko L; Williams R - relating to original article in Pharmaceutical Research (USA), Mar 1997, vol. 14, pp. 303-308.
Date: 1998
Language: English
Type: Article
Identifier: vital:6366
Description: The in vitro diffusion of progesterone from a gel formulation using the European Pharmacopoeia method for transdermal dosage forms is described. The membranes used were the dorsal and ventral portions ... More
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Date: 1998
Language: English
Type: text
Identifier: vital:6384
Description: Since the publication of the previous edition of this book there have been considerable developments and controversy in the field of topical corticosteroid bioequivalence assessment. There has been co ... More
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Authors: Smith, E W | Haigh, J M
Date: 1998
Language: English
Type: Conference paper
Identifier: vital:6342
Description: The human skin blanching (vasoconstriction) assay has been in use for 3 decades as a tool for the assessment of the release of corticosteroids from topical dosage forms. Application of corticosteroids ... More
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