https://vital.seals.ac.za/vital/access/manager/Index ${session.getAttribute("locale")} 5 Design, synthesis, characterization and evaluation of Chitosan-based hydrogel for controlled drug delivery system https://vital.seals.ac.za/vital/access/manager/Repository/vital:49969 Wed 31 Aug 2022 15:54:43 SAST ]]> Design, synthesis, manufacture, characterization and evaluation of lipid nanocapsules in chitosan-iota-carrageenan based hydrogel scaffold as a potential anti-Covid-19 drug delivery system https://vital.seals.ac.za/vital/access/manager/Repository/vital:65665 Wed 24 Jan 2024 20:14:03 SAST ]]> Large and multi scale mechanistic modeling of Diels-Alder reactions https://vital.seals.ac.za/vital/access/manager/Repository/vital:49981 Wed 20 Jul 2022 09:01:32 SAST ]]> Synthesis, characterization and host-guest complexes of supramolecular assemblies based on calixarenes and cucurbiturils https://vital.seals.ac.za/vital/access/manager/Repository/vital:65765 Wed 19 Jul 2023 10:05:25 SAST ]]> Phthalocyanine-nanoparticle conjugates supported on inorganic nanofibers as photocatalysts for the treatment of biological and organic pollutants as well as for hydrogen generation https://vital.seals.ac.za/vital/access/manager/Repository/vital:45268 Wed 16 Mar 2022 10:18:30 SAST ]]> Synthesis of pH responsive carriers for pulmonary drug delivery of anti-tuberculosis therapeutics: mesoporous silica nanoparticles and gelatin nanoparticles https://vital.seals.ac.za/vital/access/manager/Repository/vital:30590 Wed 12 May 2021 23:10:41 SAST ]]> Nonlinear optical properties of Sn(IV) phthalocyanines: experimental and theoretical approach https://vital.seals.ac.za/vital/access/manager/Repository/vital:26996 Wed 12 May 2021 22:53:00 SAST ]]> Synthesis and evaluation of arylpyrrole-chalcone hybrids as antiplasmodial and antitrypanosomal agents https://vital.seals.ac.za/vital/access/manager/Repository/vital:28716 Wed 12 May 2021 22:51:53 SAST ]]> Inhalable particulate systems for anti-tubercular drug delivery https://vital.seals.ac.za/vital/access/manager/Repository/vital:24720 Wed 12 May 2021 20:53:01 SAST ]]> Synthesis, characterisation and biological evaluation of novel anti-infective compounds bearing ferrocene, arylpyrrole, thiazolidinedione, quinoline and triazole moieties https://vital.seals.ac.za/vital/access/manager/Repository/vital:34016 Wed 12 May 2021 20:49:16 SAST ]]> Nonlinear optical responses of targeted phthalocyanines when conjugated with nanomaterials or fabricated into polymer thin films https://vital.seals.ac.za/vital/access/manager/Repository/vital:29926 Wed 12 May 2021 19:50:04 SAST ]]> Exploring Quinolinyl-Thiazolidinedione hybrid compounds as potential anti-tubercular agents https://vital.seals.ac.za/vital/access/manager/Repository/vital:38232 Wed 12 May 2021 19:47:41 SAST ]]> Symmetry and asymmetry in electrocatalysis: enhancing the electrocatalytic activity of phthalocyanines through synergy with doped graphene quantum dots https://vital.seals.ac.za/vital/access/manager/Repository/vital:34529 Wed 12 May 2021 19:30:43 SAST ]]> Photophysicochemical properties and surface-enhanced Raman scattering of phthalocyanine-nanoparticle conjugates https://vital.seals.ac.za/vital/access/manager/Repository/vital:29928 Wed 12 May 2021 19:14:28 SAST ]]> Synthesis of indium phthalocyanines for photodynamic antimicrobial chemotherapy and photo-oxidation of pollutants https://vital.seals.ac.za/vital/access/manager/Repository/vital:29116 Wed 12 May 2021 19:14:06 SAST ]]> The influence of the integration of local knowledge during chemistry hands-on practical activities on grade 8/9 learners’ attitude towards science https://vital.seals.ac.za/vital/access/manager/Repository/vital:38373 Wed 12 May 2021 18:28:38 SAST ]]> Guest inclusion behaviour of zirconium(IV)- based polycarboxylate complexes: a study of metal-organic frameworks https://vital.seals.ac.za/vital/access/manager/Repository/vital:28474 Wed 12 May 2021 18:27:48 SAST ]]> Syntheses and photophysico-chemical properties of phthalocyanines in the presence of silica nanoparticles https://vital.seals.ac.za/vital/access/manager/Repository/vital:29118 Wed 12 May 2021 18:23:20 SAST ]]> Formulation and evaluation of liposomal films for buccal delivery of antiretroviral drug https://vital.seals.ac.za/vital/access/manager/Repository/vital:34485 Wed 12 May 2021 18:15:12 SAST ]]> Nonlinear optical behavior of lanthanide phthalocyanines and their conjugates with a selection of nanomaterials https://vital.seals.ac.za/vital/access/manager/Repository/vital:20695 Wed 12 May 2021 18:14:25 SAST ]]> Enumeration, conformation sampling and population of libraries of peptide macrocycles for the search of chemotherapeutic cardioprotection agents https://vital.seals.ac.za/vital/access/manager/Repository/vital:34293 Wed 12 May 2021 17:42:00 SAST ]]> Synthesis of novel heterocyclic systems as potential inhibitors of HIV-1 enzymes https://vital.seals.ac.za/vital/access/manager/Repository/vital:38531 Wed 12 May 2021 17:09:49 SAST ]]> BODIPY dyes for singlet oxygen and optical limiting applications https://vital.seals.ac.za/vital/access/manager/Repository/vital:27014 Wed 12 May 2021 16:39:54 SAST ]]> Photophysical studies of conjugates of upconversion nanoparticles with aluminium phthalocyanines https://vital.seals.ac.za/vital/access/manager/Repository/vital:20747 Wed 12 May 2021 16:34:53 SAST ]]> Mannich base metal complexes and their thiocyanate analogues as catalysts in the oxidation of Catechol https://vital.seals.ac.za/vital/access/manager/Repository/vital:28156 Wed 12 May 2021 16:21:52 SAST ]]> Photophysical properties and photodynamic therapy activities of symmetrical and asymmetrical porphyrins embedded into Pluronic polymer micelles and nonlinear optical properties of an asymmetrical phthalocyanine https://vital.seals.ac.za/vital/access/manager/Repository/vital:29122 90% cell survival. The photodynamic activity of water insoluble porphyrins improved when encapsulated into the micelles. Novel asymmetrical phthalocyanines were also synthesised for nonlinear optics (NLO) studies in solution and thin films.]]> Wed 12 May 2021 16:05:57 SAST ]]> Characterisation, antimalarial and biological activities of secondary metabolites from leaves of anonidium mannii https://vital.seals.ac.za/vital/access/manager/Repository/vital:20725 Wed 12 May 2021 15:59:34 SAST ]]> BODIPY and porphyrin dyes for direct glucose sensing and optical limiting applications https://vital.seals.ac.za/vital/access/manager/Repository/vital:31412 Wed 12 May 2021 15:45:08 SAST ]]> Development of a protocol for extracting and quantifying the concentration of thiafentanil in blesbok (Damaliscus pygargus phillipsi) matrices 72-74 hours post administration https://vital.seals.ac.za/vital/access/manager/Repository/vital:41159 Wed 12 May 2021 15:05:22 SAST ]]> A study of the catalysis of the Diels-Alder and Aldol Condensation Reactions https://vital.seals.ac.za/vital/access/manager/Repository/vital:42947 Wed 12 May 2021 15:03:57 SAST ]]> Determination of nonlinear optical properties of phthalocyanine regioisomers using computational models https://vital.seals.ac.za/vital/access/manager/Repository/vital:41337 Wed 12 May 2021 15:02:23 SAST ]]> The electrocatalytic response of metallophthalocyanines when clicked to electrodes and to nanomaterials https://vital.seals.ac.za/vital/access/manager/Repository/vital:42174 Wed 12 May 2021 15:00:21 SAST ]]> Synthesis, photophysicochemical properties and photodynamic therapy activities of indium and zinc phthalocyanines when incorporated into Pluronic polymer micelles https://vital.seals.ac.za/vital/access/manager/Repository/vital:41489 50% cell viability) at concentrations ≤100 μg/mL, however the conjugates showed < 45% cell viability at concentrations ≤ 100 μg/mL, probably due to the small micellar size and EPR effect. The findings from this work show the importance of incorporating photosensitizers such as phthalocyanines into Pluronic polymers micelles and making them water soluble and ultimately improving their photodynamic effect.]]> Wed 12 May 2021 14:58:28 SAST ]]> Metallophthalocyanines linked to metal nanoparticles and folic acid for use in photodynamic therapy of cancer and photoinactivation of bacterial microorganisms. https://vital.seals.ac.za/vital/access/manager/Repository/vital:41377 Wed 12 May 2021 14:34:09 SAST ]]> Evaluation of metallophthalocyanine functionalized photocatalytic asymmetric polymer membranes for pollution control and antimicrobial activity https://vital.seals.ac.za/vital/access/manager/Repository/vital:42052 Wed 12 May 2021 14:30:41 SAST ]]> In vitro susceptibility of Staphylococcus aureus to porphyrin-silver mediated photodynamic antimicrobial chemotherapy https://vital.seals.ac.za/vital/access/manager/Repository/vital:41484 Wed 12 May 2021 14:28:57 SAST ]]> Development of graphene materials and phthalocyanines for application in dye-sensitized solar cells https://vital.seals.ac.za/vital/access/manager/Repository/vital:41328 Wed 12 May 2021 14:19:36 SAST ]]> Anisotropic copper oxide nanorods decorated with gold and palladium nanoparticles and their enzymatic properties https://vital.seals.ac.za/vital/access/manager/Repository/vital:42949 Wed 12 May 2021 14:17:52 SAST ]]> Synthesis, characterisation and electrocatalytic behaviour of three series of Metal Organic Frameworks https://vital.seals.ac.za/vital/access/manager/Repository/vital:41495 Wed 12 May 2021 14:08:47 SAST ]]> Design, formulation and evalauation of liposomes co-loaded with human serum Albumin and Rifampicin https://vital.seals.ac.za/vital/access/manager/Repository/vital:40670 Wed 12 May 2021 13:53:25 SAST ]]> Mapping the pyrroloiminoquinone diversity produced by latrunculid sponges using tandem mass spectrometry-driven molecular networking https://vital.seals.ac.za/vital/access/manager/Repository/vital:42942 Wed 12 May 2021 13:51:34 SAST ]]> Design, formulation and evaluation of liposomes co-loaded with human serum albumin and rifampicin https://vital.seals.ac.za/vital/access/manager/Repository/vital:41016 Wed 12 May 2021 13:50:05 SAST ]]> Photocatalysis of 4-chloro and 4-nonylphenols using novel symmetric phthalocyanines and asymmetric porphyrin supported on polyacrylonitrite nanofibres https://vital.seals.ac.za/vital/access/manager/Repository/vital:41163 Wed 12 May 2021 13:49:36 SAST ]]> Azadipyrromethenes for applications in photodynamic antimicrobial chemotherapy, photodynamic therapy and optical limiting https://vital.seals.ac.za/vital/access/manager/Repository/vital:41333 Wed 12 May 2021 13:45:15 SAST ]]> Synthesis, spectroscopic and nonlinear optical properties of asymmetric A3B type phthalocyanine complexes https://vital.seals.ac.za/vital/access/manager/Repository/vital:42108 3.76 × 10 − 10 ( 4a ) > 3.52 × 10 − 10 ( 4c ) > 2.29 × 10 − 10 ( 3c ) > 1.68 × 10 − 10 ( 3a ) > 1.65 × 10 − 10 ( 3b ) mW - 1 . The 휷 values trend of synthesized Pc complexes show that the asymmetrical A 3 B type metal free, cobalt and zinc Pc complexes ( 4a , 4b and 4c ) have larger 휷 values as compared to the octa - substituted symmetrical metal free, cobalt and zinc Pc complexes ( 3a , 3b and 3c ) which is attributed to the low symmetry of the Pc complexes. The five - level model rate equations were used to determine the two photon absorption, excited state absorption and ground state absorption cross sections of the synthesized complexes. The z inc A 3 B type asymmetrical Pc complexes gave the largest two photon absorption and 휎 푒 / 휎 푔 ratio values. This Pc complex could be used in future work to enhance the nonlinear response further by introducing nanomaterials and converting the Pc complex to a binuclear Pc. This work also reports on the density functional theory (DFT) calculations o f dipolar/octupolar contributions in order to study the first order hyperpolarizability of the synthesized Pc complexes.]]> Wed 12 May 2021 13:45:11 SAST ]]> Synthesis, In-Silico molecular modelling and biological studies of 1,4-Dihydroxyanthraquinone and its derivatives https://vital.seals.ac.za/vital/access/manager/Repository/vital:65793 Wed 10 Jan 2024 11:15:28 SAST ]]> Quinolone-Pyrazinamide Derivatives: synthesis, characterisation, in silico ADME analysis and in vitro biological evaluation against Mycobacterium tuberculosis https://vital.seals.ac.za/vital/access/manager/Repository/vital:68596 Wed 04 Oct 2023 10:47:22 SAST ]]> Ph-responsive liposomal systems for site-specific pulmonary delivery of anti-tubercular drugs https://vital.seals.ac.za/vital/access/manager/Repository/vital:35822 Wed 04 Aug 2021 14:30:34 SAST ]]> Repurposing a polymer precursor scaffold for medicinal application: Synthesis, characterization and biological evaluation of ferrocenyl 1,3-benzoxazine derivatives as potential antiprotozoal and anticancer agents https://vital.seals.ac.za/vital/access/manager/Repository/vital:41124 Wed 01 Dec 2021 08:13:26 SAST ]]> Antimalarial activity of quinoline thiosemicarbazones: synthesis and antiplasmodial evaluation https://vital.seals.ac.za/vital/access/manager/Repository/vital:56841 Tue 25 Oct 2022 14:23:47 SAST ]]> Inhibition of aluminium corrosion using phthalocyanines: Experimental and computational studies https://vital.seals.ac.za/vital/access/manager/Repository/vital:57240 Tue 25 Oct 2022 12:53:00 SAST ]]> Stable Covalent pH-Sensitive Metallophthalocyanines Thin Monolayer Films for Selective Detection of Neurotransmitters https://vital.seals.ac.za/vital/access/manager/Repository/vital:45279 Tue 16 Nov 2021 10:51:51 SAST ]]> Synthesis, characterization and antiparasitic evaluation of chalcone hybrids https://vital.seals.ac.za/vital/access/manager/Repository/vital:45271 Tue 16 Nov 2021 09:28:07 SAST ]]> Application of computational methods in elucidating the isomerization step in the biosynthesis of coumarins https://vital.seals.ac.za/vital/access/manager/Repository/vital:29124 Tue 11 Jul 2023 16:25:27 SAST ]]> Investigating cannabinoids and endocannabinoid receptors as drug targets for pain and inflammation https://vital.seals.ac.za/vital/access/manager/Repository/vital:41121 Tue 11 Apr 2023 11:15:00 SAST ]]> Green Synthesis of HIV-1 Protease Inhibitors https://vital.seals.ac.za/vital/access/manager/Repository/vital:44967 Tue 02 Nov 2021 09:08:44 SAST ]]> The elucidation of nickel and zinc based Metal Organic Frameworks (MOFs) using a polycarboxylate-benzene ligand: a synthetic, spectroscopic, and thermoanalytical study https://vital.seals.ac.za/vital/access/manager/Repository/vital:56795 Thu 22 Sep 2022 11:14:34 SAST ]]> Nonlinear optical properties of metal free thio alkyl and tert-butyl phenoxy phthalocyanine https://vital.seals.ac.za/vital/access/manager/Repository/vital:45021 1.21×10−32(C4h) > 1.05×10−32 (C2v) esu, respectively, in chloroform. Symmetry was seen to have an effect on the observed reverse saturable absorption (RSA) response. Based on the five level model rate equation nonlinear fit of the RSA response curves and Real Time Time Dependant Density Functional Theory (RT-TDDFT) results, the singlet excited state population dynamics was found to play a significant role in producing the observed Im[γ] trend.]]> Thu 17 Feb 2022 15:40:47 SAST ]]> Photocatalytic treatment of organic and inorganic water pollutants using zinc phthalocyanine-cobalt ferrite magnetic nanoparticle conjugates https://vital.seals.ac.za/vital/access/manager/Repository/vital:29119 Thu 13 May 2021 16:04:33 SAST ]]> Effect of substituents on the photophysical properties and nonlinear optical properties of asymmetrical zinc(II) phthalocyanine when conjugated to semiconductor quantum dots https://vital.seals.ac.za/vital/access/manager/Repository/vital:31404 Thu 13 May 2021 12:43:26 SAST ]]> Synthesis, characterisation and spectroscopic studies of diazine-N-oxide complexes of iron(II) towards the development of sensors https://vital.seals.ac.za/vital/access/manager/Repository/vital:31075 Thu 13 May 2021 08:45:50 SAST ]]> Physicochemical properties and photodynamic therapy activities of indium and zinc phthalocyanine-nanoparticle conjugates https://vital.seals.ac.za/vital/access/manager/Repository/vital:30589 50Îll viability at concentrations≤ 160μg/mL, however the conjugates showed<50% cell viabilityatconcentrations≤ 160μg/mLprobably due to the enhanced singlet oxygen quantum yield. The findings from this work show the importance of linking photosensitises such as phthalocyanines to metal nanoparticles for the enhancement ofsinglet oxygen quantum yield and ultimately the photodynamic effect.]]> Thu 13 May 2021 08:10:17 SAST ]]> Photosensitizer, pH sensing and optical limiting properties of BODIPY dyes https://vital.seals.ac.za/vital/access/manager/Repository/vital:28515 Thu 13 May 2021 08:06:13 SAST ]]> Antimalarial secondary metabolites from Morinda lucida https://vital.seals.ac.za/vital/access/manager/Repository/vital:25535 Thu 13 May 2021 07:33:28 SAST ]]> Synthesis and bioassay of rationally designed DXR inhibitors as potential antimalarial lead compounds https://vital.seals.ac.za/vital/access/manager/Repository/vital:20740 Thu 13 May 2021 06:56:45 SAST ]]> Effect of the nature of nanoparticles on the photophysicochemical properties and photodynamic antimicrobial chemotherapy of phthalocyanines https://vital.seals.ac.za/vital/access/manager/Repository/vital:35406 Thu 13 May 2021 06:50:34 SAST ]]> Design and fabrication of components of dye sensitised solar cells https://vital.seals.ac.za/vital/access/manager/Repository/vital:34478 Thu 13 May 2021 06:50:15 SAST ]]> Phenomenology: preconceptions and experiences of non-chemists at Rhodes University using milk paint https://vital.seals.ac.za/vital/access/manager/Repository/vital:24711 Thu 13 May 2021 06:22:30 SAST ]]> Photo-physicochemical characterization and in vitro Photodynamic Therapy Activity of Phthalocyanine-Graphene Quantum Dots Conjugates https://vital.seals.ac.za/vital/access/manager/Repository/vital:37891 Thu 13 May 2021 05:55:46 SAST ]]> Spectroscopic and electrochemical characterization of thio binuclear phthalocyanine complexes https://vital.seals.ac.za/vital/access/manager/Repository/vital:27541 Thu 13 May 2021 04:56:35 SAST ]]> Donor-acceptor effects on the optical limiting properties of BODIPY dyes https://vital.seals.ac.za/vital/access/manager/Repository/vital:28397 Thu 13 May 2021 04:20:19 SAST ]]> Spectroscopic and nonlinear optical characterisation of alpha substituted binuclear phthalocyanines https://vital.seals.ac.za/vital/access/manager/Repository/vital:20757 Thu 13 May 2021 03:07:54 SAST ]]> Physical organic studies of substituted norbornyl systems: aspects of mechanisms and chirality https://vital.seals.ac.za/vital/access/manager/Repository/vital:25999 Thu 13 May 2021 02:42:08 SAST ]]> Activity of diverse chalcones against several targets: statistical analysis of a high-throughput virtual screen of a custom chalcone library https://vital.seals.ac.za/vital/access/manager/Repository/vital:34291 Thu 13 May 2021 02:24:07 SAST ]]> Substituent effects on the electrocatalytic activity of cobalt phthalocyanine in the presence of graphene quantum dots https://vital.seals.ac.za/vital/access/manager/Repository/vital:29121 Thu 13 May 2021 01:46:43 SAST ]]> Graphene quantum dots and their metallophthalocyanines nanoconjugates as novel photoluminescent nanosensors https://vital.seals.ac.za/vital/access/manager/Repository/vital:27821 Thu 13 May 2021 01:17:53 SAST ]]> Molecular simulations of potential agents and targets of Alzheimer’s disease https://vital.seals.ac.za/vital/access/manager/Repository/vital:38523 Thu 13 May 2021 00:57:24 SAST ]]> The preparation of BODIPY and porphyrin dyes and their cyclodextrin inclusion complexes and Pluronic® F-127 encapsulation micelles for use in PDT and PACT https://vital.seals.ac.za/vital/access/manager/Repository/vital:34528 Thu 13 May 2021 00:32:13 SAST ]]> Development of a computational chemistry scheme for testing the utility of synthetic bacteriochlorin in dye-sensitized solar cells https://vital.seals.ac.za/vital/access/manager/Repository/vital:28155 Thu 13 May 2021 00:03:45 SAST ]]> Dual and targeted photodynamic therapy ablation of bacterial and cancer cells using phthalocyanines and porphyrins in the presence of carbon-based nanomaterials https://vital.seals.ac.za/vital/access/manager/Repository/vital:65804 S0 excitation energies. The small deviation observed between the calculated and experimental spectra arises from the solvent effect. The excitation energies observed in these UV-Vis spectra mostly originated from electron promotion between the highest occupied molecular orbital (HOMO) for the less intense band and the HOMO-1 for the most intense band of the ground states to the lower unoccupied molecular orbital (LUMO) of the excited states.]]> Thu 13 Jul 2023 15:22:41 SAST ]]> Development of biosensor systems for the detection of anti-cancer drugs and prostate cancer https://vital.seals.ac.za/vital/access/manager/Repository/vital:65803 Thu 13 Jul 2023 15:14:29 SAST ]]> Electrocatalytic activity of symmetric and asymmetric Co(II) and Mn(III) porphyrins in the presence of graphene quantum dots towards the oxidation of hydrazine https://vital.seals.ac.za/vital/access/manager/Repository/vital:65372 Thu 04 Jan 2024 11:00:35 SAST ]]> Photodynamic therapy using morpholine substituted porphyrins in the presence of cancer specific molecules linked to graphene quantum dots https://vital.seals.ac.za/vital/access/manager/Repository/vital:71947 Thu 04 Apr 2024 20:36:15 SAST ]]> Pharmaco-chemical investigation of Erythrina caffra: extracts, isolated compounds and their biological activities https://vital.seals.ac.za/vital/access/manager/Repository/vital:71944 Thu 04 Apr 2024 20:13:57 SAST ]]> Evaluating the potential of monometallic and bimetallic nanomaterials as horseradish peroxidase mimetics https://vital.seals.ac.za/vital/access/manager/Repository/vital:28694 Thu 02 Dec 2021 20:25:58 SAST ]]> Rapid Synthesis of Thiol-Co-Capped CdTe/CdSe/ZnSe Multi-Core-Shell QDs and Their Encapsulation in Liposomes and Chitosan Nanoparticles; Comparative Bio-compatibility Studies Using Hela and Vero Cells https://vital.seals.ac.za/vital/access/manager/Repository/vital:71962 0.5 mg/ml). The QDs also retained most of their fluorescence and properties and could easily be tracked in cells and visualized around the nucleus, indicating the successful internalization of the QDs in the cytosol. These results shows that encapsulation of CdTe multi-core-shell QDs in liposomes produce better bio-compatibility compared to multi-core-shell QDs and better than CNP coating. These particles therefore show good promise in cell-labelling, drug delivery studies. Their core-shell nanoparticles have also shown good behavior in enhancing the memory of a device which is based on some recent collaborated works.]]> Sat 06 Apr 2024 14:52:11 SAST ]]> The development of ionic zinc(II) phthalocyanines for sono-photodynamic combination therapy of cervical and breast cancer https://vital.seals.ac.za/vital/access/manager/Repository/vital:71958 Sat 06 Apr 2024 13:48:43 SAST ]]> Singlet oxygen and optical limiting applications of BODIPYs and other molecular dyes https://vital.seals.ac.za/vital/access/manager/Repository/vital:57238 Mon 24 Oct 2022 15:47:54 SAST ]]> The construction of phthalocyanine- carbon nanoparticle conjugates for applications in photodynamic therapy and non-linear optics https://vital.seals.ac.za/vital/access/manager/Repository/vital:44750 22% cell viability at concentrations ≤ 50 μg/mL relative to conjugates with <22% cell viability at concentrations ≤ 50 μg/mL. There was no direct relationship between PDT and singlet oxygen quantum yields. Nonlinear optical characteristics of complexes was improved upon conjugation of DNDs. Absorbance, input energy, percentage loading, central metal, substituent of Pc and nature of interaction (covalent, noncovalent) are amongst some of the factors that influence nonlinear absorption properties of materials used in this study. All materials followed reverse saturable absorption through two photon absorption mechanism at the excitation wavelength of 532 nm. Aggregates reduce excited state lifetime and Beff under high concentrations/absorbance. A direct relationship between absorbance and Beff of DNDs nanoconjugated systems at low concentrations result in increased optical limiting characteristics of materials. The findings from this work show the importance of linking (nonlinear optics and photodynamic therapy) and doping (photodynamic therapy) photosensitisers such as phthalocyanines and sometimes boron dipyrromethenes onto carbon based nanoparticles for the enhanced characteristics in variable applications.]]> Mon 15 Nov 2021 16:13:10 SAST ]]> A green approach for the synthesis of symmetrical and unsymmetrical 1,2,4,5-tetraoxanes as anti-protozoal agents https://vital.seals.ac.za/vital/access/manager/Repository/vital:45264 Mon 15 Nov 2021 15:06:44 SAST ]]> Synthesis and antiparasitic activity of hybrid compounds based on quinoline and thiosemicarbazone pharmacophoric units https://vital.seals.ac.za/vital/access/manager/Repository/vital:45232 Mon 15 Nov 2021 10:24:44 SAST ]]> Exploring the potential of imines as antiprotozoan agents with focus on t. Brucei and p. Falciparum https://vital.seals.ac.za/vital/access/manager/Repository/vital:28145 Mon 13 Mar 2023 12:53:24 SAST ]]> The systematic assembly of prostate specific antigen electrochemical sensors based on asymmetric Co(II) phthalocyanines, graphitic quantum dots and an aptamer https://vital.seals.ac.za/vital/access/manager/Repository/vital:50035 Mon 10 Oct 2022 08:41:01 SAST ]]> Synthesis of peptidomimetic compounds as HIV-1 protease inhibitors https://vital.seals.ac.za/vital/access/manager/Repository/vital:35604 Fri 31 Mar 2023 12:24:50 SAST ]]> Synthesis and in vitro biological evaluation of 2,3-substituted quinoline derivatives https://vital.seals.ac.za/vital/access/manager/Repository/vital:41017 Fri 31 Mar 2023 12:10:54 SAST ]]> Synthesis and evaluation of the medicinal potential of novel 4-hydroxycoumarin derivatives https://vital.seals.ac.za/vital/access/manager/Repository/vital:41120 Fri 29 Jul 2022 08:40:40 SAST ]]> The synthesis and characterisation of Sn(IV) porphyrin derivatives and their potential application in anti-cancer and antimicrobial photodynamic therapy https://vital.seals.ac.za/vital/access/manager/Repository/vital:44791 Fri 22 Oct 2021 15:54:57 SAST ]]> Characterisation of surfaces modified with phthalocyanines through click chemistry for applications in electrochemical sensing https://vital.seals.ac.za/vital/access/manager/Repository/vital:27038 Fri 17 Sep 2021 10:11:50 SAST ]]> Echogenic liposomes for ultrasound-triggered drug delivery https://vital.seals.ac.za/vital/access/manager/Repository/vital:44805 Fri 11 Feb 2022 08:50:07 SAST ]]> Photodynamic anticancer and antimicrobial activities of π-extended BODIPY dyes and cationic mitochondria-targeted porphyrins https://vital.seals.ac.za/vital/access/manager/Repository/vital:65362 Fri 07 Jul 2023 13:56:27 SAST ]]>