- Title
- In vitro antimalarial, antitrypanosomal and HIV-1 integrase inhibitory activities of two Cameroonian medicinal plants: Antrocaryon klaineanum (Anacardiaceae) and Diospyros conocarpa (Ebenaceae)
- Creator
- Fouokeng, Y
- Creator
- Feusso, H M Feumo
- Creator
- Noundou, Xavier S
- Creator
- Krause, Rui W M
- Creator
- Teinkela, Jean E Mb
- Creator
- Wintjens, R
- Creator
- Hoppe, Heinrich C
- Creator
- Azebaze, Anatole G B
- Creator
- Vardamides, Juliette C
- Creator
- Isaacs, Michelle
- Date Issued
- 2018
- Date
- 2018
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/126653
- Identifier
- vital:35908
- Identifier
- https://doi.org/10.1016/j.sajb.2018.10.008
- Description
- Antiplasmodial, antitrypanosomal and anti-HIV-1 activities of crude extracts, fractions and some isolated compounds from two Cameroonian medicinal plants: Antrocaryon klaineanum Pierre (Anacardiaceae) and Diospyros conocarpa Gürke ex K. Schum. (Ebenaceae) were assessed. The phytochemical studies led to the isolation of eight compounds (1–8) from Diospyros conocarpa and six compounds (6, 9–13) from Antrocaryon klaineanum. These compounds were identified as mangiferolic acid (1), 3β, 22(S)-dihydroxycycloart-24E-en-26-oic acid (2), lupeol (3), aridanin (4), betulin (5), betulinic acid (6), bergenin (7), D-quercitol(8), entilin C(9), entilin A(10), antrocarine A(11), 7R,20(S)-dihydroxy-4,24(28)-ergostadien-3-one(12) and stigmasterol glucoside (13). The criteria for activity were set as follows: an IC50 value
- Format
- 8 pages
- Format
- Language
- English
- Relation
- South African Journal of Botany
- Relation
- Fouokeng, Y., Feusso, H.F., Teinkela, J.M., Noundou, X.S., Wintjens, R., Isaacs, M., Hoppe, H.C., Krause, R.W.M., Azebaze, A.G.B. and Vardamides, J.C., 2019. In vitro antimalarial, antitrypanosomal and HIV-1 integrase inhibitory activities of two Cameroonian medicinal plants: Antrocaryon klaineanum (Anacardiaceae) and Diospyros conocarpa (Ebenaceae). South African Journal of Botany, 122, pp.510-517.
- Relation
- South African Journal of Botany number 122 510 517 2018 0254-6299
- Rights
- South African Journal of Botany
- Rights
- Use of this resource is governed by the terms and conditions of the Elsevier Terms and Conditions Statement (https://www.elsevier.com/legal/elsevier-website-terms-and-conditions)
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Krause, Rui Werner Maçedo (Prof)
Hoppe, Heinrich C (Prof)
Isaacs, Michelle (Mrs)
RU Department of Chemistry
SDG 03. Good Health and Well-Being
RU Department of Biochemistry, Microbiology and Bioinformatics
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