- Title
- Hepatitis C and HIV Coinfection in Developing Countries:
- Creator
- Tastan Bishop, Özlem
- Date Issued
- 2018
- Date
- 2018
- Type
- text
- Type
- book
- Identifier
- http://hdl.handle.net/10962/148228
- Identifier
- vital:38721
- Identifier
- ISBN 9780128032343
- Identifier
- https://books.google.co.za/books?id=XSmlCgAAQBAJanddq=hepatitis+c+in+developing+countriesandsource=gbs_navlinks_s
- Description
- Because of the common routes of transmission, hepatitis C virus (HCV) coinfection with HIV is frequent. Of the 36.6 million HIV-infected individuals worldwide, about 25% are also coinfected with HCV. Developing countries face the greatest burden of coinfection. HIV infection has been shown to have a significant impact on the progression of chronic HCV, with a higher risk of cirrhosis and hepatocellular carcinoma (HCC). Because of the improvements in the management and treatment of HIV/AIDS in resource-limited countries, HCV/HIV coinfection is becoming a significant clinical problem and a major cause of morbidity and mortality. HCV/HIV coinfection is characterized by aggressive hepatic fibrogenesis, incidence of cirrhosis, and HCC. HCC is currently a major cause for liver-related deaths in HIV patients. Viral eradication has been difficult to attain with interferon and ribavirin therapies. Novel therapies with direct-acting antiviral agents have been promising for this population. However, access to such expensive regimen is far beyond the capabilities of most resource-limited countries. Yet, studies lag behind those for HCV monoinfection.
- Format
- 20 pages
- Format
- Publisher
- Academic Press
- Language
- English
- Relation
- Bishop, O.T., 2018. Hepatitis C and HIV Coinfection in Developing Countries. In Hepatitis C in Developing Countries (pp. 135-155). Academic Press.
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the Elsevier Terms and conditions statement (https://www.elsevier.com/legal/elsevier-website-terms-and-conditions)
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| View Details Download | SOURCE1 | Hepatitis C and HIV Coinfection in Developing Countries.pdf | 577 KB | Adobe Acrobat PDF | View Details Download |