- Title
- Antiviral drug discovery: preparing for the next pandemic
- Creator
- Adamson, Catherine S
- Creator
- Chibale, Kelly
- Creator
- Goss, Rebecca J M
- Creator
- Jaspars, Marcel
- Creator
- Newman, David J
- Creator
- Dorrington, Rosemary A
- Date Issued
- 2021
- Date
- 2021
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/177499
- Identifier
- vital:42827
- Identifier
- DOI: 10.1039/d0cs01118e
- Description
- Clinically approved antiviral drugs are currently available for only 10 of the more than 220 viruses known to infect humans. The SARS-CoV-2 outbreak has exposed the critical need for compounds that can be rapidly mobilised for the treatment of re-emerging or emerging viral diseases, while vaccine development is underway. We review the current status of antiviral therapies focusing on RNA viruses, highlighting strategies for antiviral drug discovery and discuss the challenges, solutions and options to accelerate drug discovery efforts.
- Format
- 9 pages
- Format
- Language
- English
- Relation
- Chemical Society Reviews
- Relation
- Adamson, C.S., Chibale, K., Goss, R.J., Jaspars, M., Newman, D.J. and Dorrington, R.A., 2021. Antiviral drug discovery: preparing for the next pandemic. Chemical Society Reviews. 50, pp. 3647-3655
- Relation
- Chemical Society Reviews volume 50 number 3647 3655 2021 1460-4744
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the Royal Society of Chemistry Terms and Conditions Statement (https://0-www.rsc.org.wam.seals.ac.za/help-legal/)
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Collections
Dorrington, Rosemary A (Prof)
RU DST/NRF SARChI for Marine Natural Products
RU Department of Biochemistry, Microbiology and Bioinformatics
SDG 03. Good Health and Well-Being
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | SOURCE1 | Antiviral drug discovery.pdf | 2 MB | Adobe Acrobat PDF | View Details Download |