- Title
- Phytomedical Studies of Medicinal Plants Traditionally Used for The Treatment of Chest and Cough Related Diseases in The Eastern Cape
- Creator
- Ndamane, Yolanda
- Date
- 2013
- Type
- Masters
- Identifier
- http://hdl.handle.net/11260/2814
- Identifier
- vital:42954
- Description
- GENERAL ABSTRACT Herbal plants play a fundamental role in the treatment of coughing and chest related diseases particularly in remote areas of Eastern Cape where health care facilities are sparsely located. The phytomedical studies of plants implicated in the treatment of coughing and chest related diseases in the OR Tambo District Municipality,Eastern Cape was investigated. This study was aimed at documenting the commonly used plants and validates their efficacy against different organisms which are notorious for causing coughing and chest related diseases. The methods employed for the present study include interviews with traditional healers, herbalist and knowledgeable rural dwellers that provided ethnobotanical information and identified 17 plants used for the treatment of coughing and chest related diseases in the study area. Of these the three medicinal plants that were reported to be most widely and frequently used by the local people as remedies for coughing and chest related diseases were Tetradenia riparia, Plectranthus laxiflarus and Eucalyptus renans. T. riparia was selected for further study based on its frequency of citation during the interviewees. Hexane, ethyl acetate, methanol, dichloromethane and Aqueous extracts of Tetradenia riparia were screened against ten bacterial species. The dichloromethane extract was the only extract that did not show any activity against bacterial strains. All other four extracts exhibited various degrees of activity with the ethyl acetate extract showing the highest activity against the bacterial species used during the antibacterial assays. Bioactivity-guided fractionation of the leaves of Tetradenia riparia yielded one pure compound. The antimicrobial investigation of the isolated compound showed inhibitory activity against all tested microorganisms. It is noteworthy that the isolated compound showed a significantly higher inhibitory activity than the actual crude extract, this is suggestive of the powerful ability of the compound in working independently.The present study has lend scientific credence to the folkloric use of T.riparia in the management of cough on chest related disorders.
- Format
- Contributor
- SONGCA, S P
- Contributor
- KAMBIZI, L
- Publisher
- Walter Sisulu University
- Language
- English
- Rights
- Walter Sisulu University
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WSU Department of Biological and Environmental Sciences
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|---|---|---|---|---|---|---|---|
| View Details Download | SOURCE1 | Yolanda Ndamane.pdf | 377 KB | Adobe Acrobat PDF | View Details Download |