- Title
- Metallophthalocyanine Based Carbon Paste Electrodes for the Determination of 2′, 3′‐Dideoxyinosine
- Creator
- Ozoemena, Kenneth I
- Creator
- Stefan-van Staden, Raluca-Ioana
- Creator
- Nyokong, Tebello
- Subject
- To be catalogued
- Date Issued
- 2009
- Date
- 2009
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/263430
- Identifier
- vital:53627
- Identifier
- xlink:href="https://doi.org/10.1002/elan.200904581"
- Description
- Novel electrochemical sensors based on carbon paste impregnated with metallopthalocyanine (MPc, M=Co, Fe) complexes, have been constructed for the assay of anti-HIV drug 2′,3′-dideoxyinosine (didanosine, DDI). Both modified electrodes showed electrocatalytic activity towards the oxidation of dideoxyinosine in phosphate buffer pH 7.4 with a working concentration range of 10−6–10−4 mol/L and a detection limit of 10−7 mol/L magnitude order. The sensor proved to be highly reliable for the assay of the purity of DDI - raw material as well as for the uniformity content test of Videx tablets.
- Format
- computer
- Format
- online resource
- Format
- application/pdf
- Format
- 1 online resource (4 pages)
- Format
- Publisher
- Wiley Library Online
- Language
- English
- Relation
- An International Journal Devoted to Fundamental and Practical Aspects of Electroanalysis
- Relation
- Ozoemena, K.I., Stefan‐van Staden, R.I. and Nyokong, T., 2009. Metallophthalocyanine Based Carbon Paste Electrodes for the Determination of 2′, 3′‐Dideoxyinosine. Electroanalysis: An International Journal Devoted to Fundamental and Practical Aspects of Electroanalysis, 21(14), pp.1651-1654
- Relation
- An International Journal Devoted to Fundamental and Practical Aspects of Electroanalysis volume 21 number 14 p. 1651 2009 1521-4109
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the Wiley Library Online Terms of Use Statement (https://onlinelibrary.wiley.com/terms-and-conditions)
- Rights
- Closed Access
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Collections
RU DST/NRF SARChI for Medicinal Chemistry and Nanotechnology
Nyokong, Tebello (Distinguished Professor)
RU Department of Chemistry
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | SOURCE1 | Metallophthalocyanine Based Carbon Paste Electrodes for the Determination.pdf | 644 KB | Adobe Acrobat PDF | View Details Download |