- Title
- Anticancer evaluation of ruthenium (III) complexes with N-donor ligands tethered to coumarin or uracil moieties:
- Creator
- Gramni, Larusha
- Creator
- Vukea, Nyeleti
- Creator
- Chakraborty, Abir
- Creator
- Samson, William J
- Creator
- Dingle, Laura M K
- Creator
- Xulu, Bheki
- Creator
- de la Mare, Jo-Anne
- Creator
- Edkins, Adrienne L
- Creator
- Booysen, Irvin N
- Date Issued
- 2019
- Date
- 2019
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/163477
- Identifier
- vital:41041
- Identifier
- DOI: 10.1016/j.ica.2019.04.01
- Description
- In this study, the synthesis and characterization of new paramagnetic ruthenium(III) complexes: cis-[RuCl2(urdpa)] (1) {Hurdpa = 6-((bis(pyridin-2-ylmethyl)amino)methyl)uracil} and fac-[RuCl3(chrdpa)] (2) {chrdpa = 4-((bis(pyridin-2-ylmethyl)amino)methyl)-7-methoxycoumarin} are reported. These metal complexes have been comprehensively characterized by an array of physicochemical techniques and the X-ray solid-state structures of 1 and Hurdpa have been attained.
- Format
- Language
- English
- Relation
- Inorganica Chimica Acta
- Relation
- Gramni, L., Vukea, N., Chakraborty, A., Samson, W.J., Dingle, L.M.K., Xulu, B., de la Mare, J.A., Edkins, A.L. and Booysen, I.N., 2019. Anticancer evaluation of ruthenium (III) complexes with N-donor ligands tethered to coumarin or uracil moieties. Inorganica Chimica Acta, 492, pp.98-107
- Relation
- Inorganica Chimica Acta volume 492 number 98 107 June 2019 0020-1693
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the Elsevier Terms and Conditions Statement (https://www.elsevier.com/legal/elsevier-website-terms-and-conditions)
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RU DST/NRF SARChI for Molecular and Cellular Biology of the Eukaryotic Stress Response
De la Mare, Jo-Anne (Dr)
Edkins, Adrienne Lesley (Associate Prof)
RU Department of Biochemistry, Microbiology and Bioinformatics
SDG 03. Good Health and Well-Being
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