- Title
- The extent and impact of variation in ADME genes in sub-Saharan African populations
- Creator
- da Rocha, Jorge E B
- Creator
- Othman, Houcemeddine
- Creator
- Botha, Gerrit
- Creator
- Cottino, Laura
- Creator
- Twesigomwe, David
- Creator
- Ahmed, Samah
- Creator
- Drögemöller, Britt I
- Creator
- Fadlelmola, Faisal M
- Creator
- Machanick, Philip
- Creator
- Mbiyavanga, Mamana
- Creator
- Panji, Sumir
- Creator
- Wright, Galen E B
- Creator
- Adebamowo, Clement
- Creator
- Matshaba, Mogomotsi
- Creator
- Ramsay, Michéle
- Creator
- Simo, Gustave
- Creator
- Simuunza, Martin C
- Creator
- Tiemessen, Caroline T
- Creator
- Baldwin, Sandra
- Creator
- Chiano, Mathias
- Creator
- Cox, Charles
- Creator
- Gross, Annette S
- Creator
- Thomas, Pamela
- Creator
- Gamo, Francisco-Javier
- Creator
- Scott Hazelhurst
- Subject
- To be catalogued
- Date Issued
- 2022
- Date
- 2022
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/439202
- Identifier
- vital:73555
- Identifier
- https://homes.cs.ru.ac.za/philip/Courses/CSHonsArch/HonsArchNotes2022.pdf
- Description
- Investigating variation in genes involved in the absorption, distribution, metabolism, and excretion (ADME) of drugs are key to characterizing pharmacogenomic (PGx) relationships. ADME gene variation is relatively well characterized in European and Asian populations, but data from African populations are under-studied—which has implications for drug safety and effective use in Africa.
- Format
- 182 pages
- Format
- Language
- English
- Relation
- Rhodes University
- Relation
- Da Rocha, J.E., Othman, H., Botha, G., Cottino, L., Twesigomwe, D., Ahmed, S., Drögemöller, B.I., Fadlelmola, F.M., Machanick, P., Mbiyavanga, M. and Panji, S., 2021. The extent and impact of variation in ADME genes in sub-Saharan African populations. Frontiers in Pharmacology, 12, p.634016
- Relation
- Rhodes University volume 2022 number 1 1 182 2022 1865-0937
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of Philip Machanick in the RAMpage Research imprint under an Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) licence: http://creativecommons.org/licenses/by-nc/4.0/
- Hits: 826
- Visitors: 733
- Downloads: 17
Collections
Machanick, Philip (Assoc Prof)
RU Department of Computer Science
SDG 09. Industry, Innovation and Infrastructure
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | SOURCE1 | The extent and impact of variation in ADME genes in sub-Saharan African populations (2).pdf | 3 MB | Adobe Acrobat PDF | View Details Download |