- Title
- A search for enhanced photodynamic activity against Staphylococcus aureus planktonic cells and biofilms: the evaluation of phthalocyanine–detonation nanodiamond–Ag nanoconjugates
- Creator
- Openda, Yolande Ikala
- Creator
- Matshitse, Refilwe
- Creator
- Nyokong, Tebello
- Date Issued
- 2020
- Date
- 2020
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/163825
- Identifier
- vital:41073
- Identifier
- DOI: 10.1039/D0PP00075B
- Description
- The present work reports on the synthesis and characterization of novel zinc (2) and indium (3) 2-amino-4-bromophenoxy substituted phthalocyanines (Pcs) along with the self-assembled nanoconjugates formed via π–π stacking interaction onto detonation nanodiamonds (DNDs) to form 2@DNDs and 3@DNDs. 2@DNDs and 3@DNDs were covalently linked to chitosan–silver mediated nanoparticles (CSAg) to form 2@DNDs-CSAg and 3@DNDs-CSAg nanoconjugates. High singlet oxygen quantum yields in DMSO of 0.69 and 0.72 for Pcs alone and 0.90 and 0.92 for 2@DNDs-CSAg and 3@DNDs-CSAg, respectively, were obtained.
- Format
- 14 pages
- Format
- Language
- English
- Relation
- Photochemical and Photobiological Sciences
- Relation
- Openda, Y.I., Matshitse, R. and Nyokong, T., 2020. A search for enhanced photodynamic activity against Staphylococcus aureus planktonic cells and biofilms: the evaluation of phthalocyanine–detonation nanodiamond–Ag nanoconjugates. Photochemical and Photobiological Sciences, 19(10), pp.1442-1454
- Relation
- Photochemical and Photobiological Sciences volume 19 number 10 1442 1454 September 2020 1474-9092
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the Royal Society of Chemistry Terms and Conditions Statement (https://0-www.rsc.org.wam.seals.ac.za/help-legal/)
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Collections
RU DST/NRF SARChI for Medicinal Chemistry and Nanotechnology
Nyokong, Tebello (Distinguished Professor)
RU Department of Chemistry
SDG 03. Good Health and Well-Being
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