Susceptibility of Staphylococcus aureus to porphyrin-silver nanoparticle mediated photodynamic antimicrobial chemotherapy

Shabangu, Samuel M; Soy, Rodah C

Title: Susceptibility of Staphylococcus aureus to porphyrin-silver nanoparticle mediated photodynamic antimicrobial chemotherapy
Creator: Shabangu, Samuel M
Creator: Babu, Balaji
Creator: Soy, Rodah C
Creator: Ovim, James
Creator: Amuhaya, Edith K
Creator: Nyokong, Tebello
Subject: To be catalogued
Date Issued: 2020
Date: 2020
Type: text
Type: article
Identifier: http://hdl.handle.net/10962/186262
Identifier: vital:44479
Identifier: xlink:href="https://doi.org/10.1016/j.jlumin.2020.117158"
Description: Photodynamic antimicrobial chemotherapy (PACT) is employed against multi drug resistant Staphylococcus aureus using porphyrins combined with silver nanoparticles to bring about a combined photodynamic effect. We employ Zn-meso-5,10,15,20-tetra(4-pyridyl) (1), Zn-meso-5,10,15,20-tetrathienyl (2), and Zn-meso-5-(4- hydroxyphenyl)- 10,15,20-tris(2-thienyl)(3) porphyrins and their self-assembled conjugates with silver nanoparticles for PACT against Staphylococcus aureus. Complex 3 with nanoparticles was found to perform better resulting in 0% bacterial viability at 60 min.
Format: computer
Format: online resource
Format: application/pdf
Format: 1 online resource (9 pages)
Format: pdf
Publisher: Elsevier
Language: English
Relation: Journal of Luminescence
Relation: Journal of Luminescence volume 222 p. 117158 2020 0022-2313
Rights: Publisher
Rights: Use of this resource is governed by the terms and conditions of the Elsevier Terms and Conditions Statement (https://www.elsevier.com/legal/elsevier-website-terms-and-conditions)
Rights: Closed Access

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RU DST/NRF SARChI for Medicinal Chemistry and Nanotechnology

Nyokong, Tebello (Distinguished Professor)

RU Department of Chemistry

SDG 03. Good Health and Well-Being

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