The Effect of Cardiorespiratory Exercise in the Prevention and Treatment of Hypertension among HIV-Infected Individuals on Antiretroviral Therapy in Mthatha, South Africa
- Tsuro, Urgent, Oladimeji, Elizabeth Kelechi, Pulido-Estrada, Guillermo-Alfredo, Apalata, Ruffin Teke
- Authors: Tsuro, Urgent , Oladimeji, Elizabeth Kelechi , Pulido-Estrada, Guillermo-Alfredo , Apalata, Ruffin Teke
- Date: 2023/05
- Subjects: Cardiorespiratory fitness , Concurrent training , Hypertension , HIV , Black people , Randomized control trial
- Language: English
- Type: Article
- Identifier: http://hdl.handle.net/11260/13577 , vital:78958 , DOI: https://doi.org/10.3390/healthcare11131836
- Description: Tuberculosis (TB), a disease of poverty and inequality, is a leading cause of severe illness and death among people with human immunodeficiency virus (HIV). In South Africa, both TB and HIV epidemics have been closely related and persistent, posing a significant burden for healthcare provision. Studies have observed that TB-HIV integration reduces mortality. The operational implementation of integrated services is still challenging. This study aimed to describe patients’ perceptions on barriers to scaling up of TB-HIV integration services at selected health facilities (study sites) in Oliver Reginald (O.R) Tambo Municipality, Eastern Cape province, South Africa. We purposely recruited twenty-nine (29) patients accessing TB and HIV services at the study sites. Data were analyzed using qualitative content analysis and presented as emerging themes. Barriers identified included a lack of health education about TB and HIV; an inadequate counselling for HIV and the antiretroviral drugs (ARVs); and poor quality of services provided by the healthcare facilities. These findings suggest that the O.R. Tambo district needs to strengthen its TB-HIV integration immediately.
- Full Text:
- Date Issued: 2023/05
- Authors: Tsuro, Urgent , Oladimeji, Elizabeth Kelechi , Pulido-Estrada, Guillermo-Alfredo , Apalata, Ruffin Teke
- Date: 2023/05
- Subjects: Cardiorespiratory fitness , Concurrent training , Hypertension , HIV , Black people , Randomized control trial
- Language: English
- Type: Article
- Identifier: http://hdl.handle.net/11260/13577 , vital:78958 , DOI: https://doi.org/10.3390/healthcare11131836
- Description: Tuberculosis (TB), a disease of poverty and inequality, is a leading cause of severe illness and death among people with human immunodeficiency virus (HIV). In South Africa, both TB and HIV epidemics have been closely related and persistent, posing a significant burden for healthcare provision. Studies have observed that TB-HIV integration reduces mortality. The operational implementation of integrated services is still challenging. This study aimed to describe patients’ perceptions on barriers to scaling up of TB-HIV integration services at selected health facilities (study sites) in Oliver Reginald (O.R) Tambo Municipality, Eastern Cape province, South Africa. We purposely recruited twenty-nine (29) patients accessing TB and HIV services at the study sites. Data were analyzed using qualitative content analysis and presented as emerging themes. Barriers identified included a lack of health education about TB and HIV; an inadequate counselling for HIV and the antiretroviral drugs (ARVs); and poor quality of services provided by the healthcare facilities. These findings suggest that the O.R. Tambo district needs to strengthen its TB-HIV integration immediately.
- Full Text:
- Date Issued: 2023/05
Treatment Outcomes and Associated Factors among Tuberculosis Patients from Selected Rural Eastern Cape Hospitals: An Ambidirectional Study
- Faye, M Lindiwe, Hosu, C Mojisola, Iruedo, Joshua, Nokoyo, A Kolisa, Tsuro, Urgent, Apalata, Teke
- Authors: Faye, M Lindiwe , Hosu, C Mojisola , Iruedo, Joshua , Nokoyo, A Kolisa , Tsuro, Urgent , Apalata, Teke
- Date: 2023
- Subjects: Treatment outcomes , DR-TB, MDR-TB, TB-HIV , Co-infection , Treatment success rate
- Language: English
- Type: Article
- Identifier: http://hdl.handle.net/11260/13637 , vital:78967 , DOI: https://doi.org/10.3390/tropicalmed8060315
- Description: An essential metric for determining the efficacy of tuberculosis (TB) control programs is the evaluation of TB treatment outcomes; this study was conducted to investigate treatment outcomes and associated factors among tuberculosis patients in rural areas of Eastern Cape, South Africa. Assessing treatment outcomes is fundamental to facilitating the End TB Strategy’s set target. Clinic records from 457 patients with DR-TB were examined for data collection while 101 patients were followed up prospectively. Data were analyzed using Stata version 17.0. The odds ratio and 95% confidence interval were calculated to check the association between variables. p ≤ 0.05 was considered statistically significant. Of the 427 participants, 65.8% had successful treatment whilst 34.2% had unsuccessful TB treatment. A total of 61.2% and 39% of the HIV-positive and HIV-negative participants had a successful TB treatment whilst 66% and 34% of both HIV-negative and positive participants had unsuccessful TB treatment. From the 101 patients that were followed up, smokers took longer to have treatment outcomes compared to non-smokers. In the study with HIV/TB co-infection, men predominated. HIV and tuberculosis co-infection made therapy difficult with unfavorable effects on TB management. The treatment success rate (65.8%) was lower than the WHO threshold standard with a high proportion of patients being lost to the follow up. The co-infection of tuberculosis and HIV resulted in undesirable treatment outcomes. Strengthening TB surveillance and control is recommended.
- Full Text:
- Date Issued: 2023
- Authors: Faye, M Lindiwe , Hosu, C Mojisola , Iruedo, Joshua , Nokoyo, A Kolisa , Tsuro, Urgent , Apalata, Teke
- Date: 2023
- Subjects: Treatment outcomes , DR-TB, MDR-TB, TB-HIV , Co-infection , Treatment success rate
- Language: English
- Type: Article
- Identifier: http://hdl.handle.net/11260/13637 , vital:78967 , DOI: https://doi.org/10.3390/tropicalmed8060315
- Description: An essential metric for determining the efficacy of tuberculosis (TB) control programs is the evaluation of TB treatment outcomes; this study was conducted to investigate treatment outcomes and associated factors among tuberculosis patients in rural areas of Eastern Cape, South Africa. Assessing treatment outcomes is fundamental to facilitating the End TB Strategy’s set target. Clinic records from 457 patients with DR-TB were examined for data collection while 101 patients were followed up prospectively. Data were analyzed using Stata version 17.0. The odds ratio and 95% confidence interval were calculated to check the association between variables. p ≤ 0.05 was considered statistically significant. Of the 427 participants, 65.8% had successful treatment whilst 34.2% had unsuccessful TB treatment. A total of 61.2% and 39% of the HIV-positive and HIV-negative participants had a successful TB treatment whilst 66% and 34% of both HIV-negative and positive participants had unsuccessful TB treatment. From the 101 patients that were followed up, smokers took longer to have treatment outcomes compared to non-smokers. In the study with HIV/TB co-infection, men predominated. HIV and tuberculosis co-infection made therapy difficult with unfavorable effects on TB management. The treatment success rate (65.8%) was lower than the WHO threshold standard with a high proportion of patients being lost to the follow up. The co-infection of tuberculosis and HIV resulted in undesirable treatment outcomes. Strengthening TB surveillance and control is recommended.
- Full Text:
- Date Issued: 2023
Modelling the impact of risk factors affecting TB treatment
- Authors: Tsuro, Urgent
- Date: 2013
- Subjects: Diseases -- Risk factors , Tuberculosis -- Epidemiology , Multidrug resistance
- Language: English
- Type: Thesis , Masters , MSc (Biostatistics and Epidemiology)
- Identifier: vital:11787 , http://hdl.handle.net/10353/d1019782 , Diseases -- Risk factors , Tuberculosis -- Epidemiology , Multidrug resistance
- Description: The Tuberculosis infection rate has been generally escalating due to poor health conditions in the Gweru district of Zimbabwe. The study therefore seeks to identify the risk factors that affect TB treatment in the Gweru district. A cross sectional study was carried out in which a questionnaire was employed for data collection on 113 respondents. A binary logistic regression model was employed for data analysis. A total of 98 TB patients were interviewed: [50 respondents (44.0%) had Multi-drug resistant Tuberculosis and 63 respondents (56.0%) had general Tuberculosis). Before being enrolled into the study, an informed consent form was given to each of the participants. The data was then put into excel and later transferred to SPSS for analysis. Out of the 14 potential risk factors of TB treatment, only 6 variables (side effects, gender, alcohol use, HIV status, smoking during the treatment period and having been pre-exposed to TB drugs) were statistically significant in their association with treatment failure.
- Full Text:
- Date Issued: 2013
- Authors: Tsuro, Urgent
- Date: 2013
- Subjects: Diseases -- Risk factors , Tuberculosis -- Epidemiology , Multidrug resistance
- Language: English
- Type: Thesis , Masters , MSc (Biostatistics and Epidemiology)
- Identifier: vital:11787 , http://hdl.handle.net/10353/d1019782 , Diseases -- Risk factors , Tuberculosis -- Epidemiology , Multidrug resistance
- Description: The Tuberculosis infection rate has been generally escalating due to poor health conditions in the Gweru district of Zimbabwe. The study therefore seeks to identify the risk factors that affect TB treatment in the Gweru district. A cross sectional study was carried out in which a questionnaire was employed for data collection on 113 respondents. A binary logistic regression model was employed for data analysis. A total of 98 TB patients were interviewed: [50 respondents (44.0%) had Multi-drug resistant Tuberculosis and 63 respondents (56.0%) had general Tuberculosis). Before being enrolled into the study, an informed consent form was given to each of the participants. The data was then put into excel and later transferred to SPSS for analysis. Out of the 14 potential risk factors of TB treatment, only 6 variables (side effects, gender, alcohol use, HIV status, smoking during the treatment period and having been pre-exposed to TB drugs) were statistically significant in their association with treatment failure.
- Full Text:
- Date Issued: 2013
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