The development of biological tools to aid in the genetic investigation of the black (Diceros bicornis) and white (Ceratotherium simum) rhinoceros mitochondrial genomes
- Authors: Parsons, Michelle
- Date: 2015
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/56059 , vital:26769
- Description: The black (Diceros bicornis) and white (Ceratotherium simum) rhinoceros are found in South Africa. A decline in the populations of these species has resulted due to human activities such as habitat fragmentation and poaching. This has contributed to the loss of genetic diversity amongst the black and white rhinoceros. Conservation and anti-poaching efforts are needed to help maintain genetic diversity. These efforts could be improved through the development of non-invasive techniques to examine DNA from threatened animals. The aim of this research was to develop a molecular technique which would allow for the identification of the black and white rhinoceros and to develop a molecular technique which would allow for intraspecies genetic variation to be examined. DNA extractions were performed on matched faecal and tissue samples that were collected from two regions in South Africa. Polymerase chain reaction (PCR) primer sets were designed to investigate several regions of the rhinoceros mitochondrial genome. PCR optimisation was completed for the target regions. Sequencing was conducted on all final PCR products. The cytochrome c oxidase subunit 1 (COIi) gene allowed for the rhinoceros family to be identified. This region was digested with the HindIII restriction enzyme, which allowed for the specific identification of either the black or white rhinoceros. A subsequent region of the cytochrome c oxidase subunit 1 (COIii) as well as the D-loop, hypervariable regions (HV1 and HV2), cytochrome b (cytb) and 16s rRNA regions were investigated. These regions displayed potential for establishing geographic origin for black rhinoceros samples, whereas the D-loop and HV2 show potential for the white rhinoceros. The white rhinoceros displayed sequence variation in the HV2 and cytb region, while variation was observed in the COIi and HV1 for the black rhinoceros. All investigated target regions allowed for the rhinoceros family to be identified. The COI (COIi and COIii), HV2 and cytb regions allowed for the subspecies of rhinoceros to be identified, however the D-loop was not able to identify the white rhinoceros species. The 16s rRNA and HV1 regions allowed for the correct subspecies of rhinoceros to be identified, however as the primers were only compatible for the black rhinoceros therefore a subsequent investigation is required for the white rhinoceros. The establishment of this novel PCR based technique to identify white and black rhinoceros will allow for efficient species identification in wildlife forensic cases. A biological method was established to study intraspecies variation for the white and black rhinoceros; however the investigated target regions did not yield sufficient genetic variation. The core techniques developed in this study will be valuable for future studies that wish to investigate genetic variation in mammal species.
- Full Text:
- Date Issued: 2015
- Authors: Parsons, Michelle
- Date: 2015
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/56059 , vital:26769
- Description: The black (Diceros bicornis) and white (Ceratotherium simum) rhinoceros are found in South Africa. A decline in the populations of these species has resulted due to human activities such as habitat fragmentation and poaching. This has contributed to the loss of genetic diversity amongst the black and white rhinoceros. Conservation and anti-poaching efforts are needed to help maintain genetic diversity. These efforts could be improved through the development of non-invasive techniques to examine DNA from threatened animals. The aim of this research was to develop a molecular technique which would allow for the identification of the black and white rhinoceros and to develop a molecular technique which would allow for intraspecies genetic variation to be examined. DNA extractions were performed on matched faecal and tissue samples that were collected from two regions in South Africa. Polymerase chain reaction (PCR) primer sets were designed to investigate several regions of the rhinoceros mitochondrial genome. PCR optimisation was completed for the target regions. Sequencing was conducted on all final PCR products. The cytochrome c oxidase subunit 1 (COIi) gene allowed for the rhinoceros family to be identified. This region was digested with the HindIII restriction enzyme, which allowed for the specific identification of either the black or white rhinoceros. A subsequent region of the cytochrome c oxidase subunit 1 (COIii) as well as the D-loop, hypervariable regions (HV1 and HV2), cytochrome b (cytb) and 16s rRNA regions were investigated. These regions displayed potential for establishing geographic origin for black rhinoceros samples, whereas the D-loop and HV2 show potential for the white rhinoceros. The white rhinoceros displayed sequence variation in the HV2 and cytb region, while variation was observed in the COIi and HV1 for the black rhinoceros. All investigated target regions allowed for the rhinoceros family to be identified. The COI (COIi and COIii), HV2 and cytb regions allowed for the subspecies of rhinoceros to be identified, however the D-loop was not able to identify the white rhinoceros species. The 16s rRNA and HV1 regions allowed for the correct subspecies of rhinoceros to be identified, however as the primers were only compatible for the black rhinoceros therefore a subsequent investigation is required for the white rhinoceros. The establishment of this novel PCR based technique to identify white and black rhinoceros will allow for efficient species identification in wildlife forensic cases. A biological method was established to study intraspecies variation for the white and black rhinoceros; however the investigated target regions did not yield sufficient genetic variation. The core techniques developed in this study will be valuable for future studies that wish to investigate genetic variation in mammal species.
- Full Text:
- Date Issued: 2015
Inspection of telegraph line
- Authors: McKay, G. , Brownlee, C.
- Date: 1868
- Language: English
- Type: cartographic
- Identifier: http://hdl.handle.net/10962/105127 , vital:32467
- Description: Inspection of telegraph line - G. McKay, East London to Potsdam - C. Brownlee, King Williams Town to Potsdam; [comp. by G. McKay?].Scale not stated. 1 sheet 14½" x 22". Manuscript; may be dated "1868".
- Full Text: false
- Authors: McKay, G. , Brownlee, C.
- Date: 1868
- Language: English
- Type: cartographic
- Identifier: http://hdl.handle.net/10962/105127 , vital:32467
- Description: Inspection of telegraph line - G. McKay, East London to Potsdam - C. Brownlee, King Williams Town to Potsdam; [comp. by G. McKay?].Scale not stated. 1 sheet 14½" x 22". Manuscript; may be dated "1868".
- Full Text: false
Primeness in near-rings of continuous maps
- Authors: Mogae, Kabelo
- Subjects: Near-rings , Topological algebras
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:10512 , http://hdl.handle.net/10948/d1020597
- Description: The prototype of a near-ring is the set of all self-maps of an additively written (but not necessarily abelian) group under pointwise addition and composition of maps. Moreover, any near-ring with unity can be embedded in a near-ring (with unity) of self-maps of some group. For this reason, a lot of research has been done on near-rings of maps. In 1979, Hofer [16] gave the study of near-rings of maps a topological avour by considering the near- ring of all continuous self-maps of a topological group. In this dissertation we consider some standard constructions of near-rings of maps on a group G and investigate these when G is a topological group and our near-ring consists of continuous maps.
- Full Text:
- Authors: Mogae, Kabelo
- Subjects: Near-rings , Topological algebras
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:10512 , http://hdl.handle.net/10948/d1020597
- Description: The prototype of a near-ring is the set of all self-maps of an additively written (but not necessarily abelian) group under pointwise addition and composition of maps. Moreover, any near-ring with unity can be embedded in a near-ring (with unity) of self-maps of some group. For this reason, a lot of research has been done on near-rings of maps. In 1979, Hofer [16] gave the study of near-rings of maps a topological avour by considering the near- ring of all continuous self-maps of a topological group. In this dissertation we consider some standard constructions of near-rings of maps on a group G and investigate these when G is a topological group and our near-ring consists of continuous maps.
- Full Text:
Development and optimisation of a novel Plasmodium falciparum Hsp90-Hop interaction assay
- Authors: Wambua, Lynn
- Date: 2018
- Subjects: Plasmodium falciparum , Molecular chaperones , Heat shock proteins , Protein-protein interactions , Antimalarials
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/62626 , vital:28216
- Description: Protein-protein interactions are involved in a range of disease processes and thus have become the focus of many drug discovery programs. Widespread drug resistance to all currently used antimalarial drugs drives the search for alternative drug targets with novel mechanisms of action that offer new therapeutic options. Molecular chaperones such as heat shock proteins facilitate protein folding, play a role in protein trafficking and prevent protein misfolding in cells under stress. Heat shock protein 90 (Hsp90) is a well-studied chaperone that has been the focus of cancer drug development with moderate success. In Plasmodium falciparum (P. falciparum), heat shock proteins are thought to play a vital role in parasite survival of the physiologically diverse habitats of the parasite lifecycle and because Hsp90 is prominently expressed in P. falciparum, the chaperone is considered a potentially ideal drug target. Hsp90 function in cells is regulated by interactions with co-chaperones, which includes Heat shock protein 70-Heat shock protein 90 organising protein (Hop). As opposed to directly inhibiting Hsp90 activity, targeting Hsp90 interaction with Hop has recently been suggested as an alternative method of Hsp90 inhibition that has not been explored in P. falciparum. The aim of this research project was to demonstrate PfHsp90 and PfHop robustly interact in vitro and to facilitate high-throughput screening of PfHsp90-PfHop inhibitors by developing and optimising a novel plate capture Hsp90-Hop interaction assay. To establish the assay, the respective domains of the proteins that mediate Hsp90-Hop interaction were used (Hsp90 C- terminal domain and Hop TPR2A domain). The human Hsp90 C-terminal domain and glutathione-S-transferase (GST) coding sequences were cloned into pET-28a(+) and murine and P. falciparum TPR2A sequences into pGEX-4T-1 plasmids to enable expression of histidine-tagged and GST fusion proteins, respectively, in Escherichia coli. The P. falciparum Hsp90 C-terminal domain sequence cloned into pET-28a(+) was supplied by GenScript. The constructs were transformed into T7 Express lysYcompetent E. coli cells and subsequent small- scale expression studies showed the recombinant proteins were expressed in a soluble form allowing for subsequent protein purification. Purification of the recombinant proteins was achieved using nickel-NTA and glutathione affinity chromatography for the His-tagged (Hsp90 C-terminal domains and GST) and GST fusion proteins (TPR2A domains), respectively. The purified proteins were used to establish and optimise mammalian and P. falciparum Hsp90- Hop interaction assays on nickel-coated plates by immobilising the His-tagged C-terminal domains on the plates and detecting the binding of the GST-TPR2A domains using a colorimetric GST enzyme assay. Z’-factor values above 0.5 were observed for both assays indicating good separation between the protein interaction signals and negative control background signals, although relatively high background signals were observed for the mammalian interaction due to non-specific binding of murine TPR2A to the plate. Designed human and P. falciparum TPR peptides were observed to be effective inhibitors of the mammalian and P. falciparum interactions, demonstrating the assay’s ability to respond to inhibitor compounds. Comparison of assay performance using GST assay kit reagents and lab- prepared reagents showed the assay was more efficient using lab-prepared reagents, however, lower GST signals were observed when comparing assay performance using a custom prepared Ni-NTA plate to a purchased Ni-NTA plate. The Hsp90-Hop interaction assays were also performed using an alternative assay format in which the GST-TPR2A fusion proteins were immobilised on glutathione-coated plates and binding of the His-tagged C-terminal domains detected with a nickel-horseradish peroxidase (HRP) conjugate and a colorimetric HRP substrate. The assay showed higher interaction signals for the P. falciparum proteins but comparatively low signals for the mammalian proteins. Z’-factor values for the assay were above 0.8 for both protein sets, suggesting this assay format is superior to the GST assay. However, further optimisation of this assay format is required. This study demonstrated direct binding of PfHsp90-PfHop in vitro and established a novel and robust PfHsp90-PfHop interaction assay format that can be used in future screening campaigns.
- Full Text:
- Date Issued: 2018
- Authors: Wambua, Lynn
- Date: 2018
- Subjects: Plasmodium falciparum , Molecular chaperones , Heat shock proteins , Protein-protein interactions , Antimalarials
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/62626 , vital:28216
- Description: Protein-protein interactions are involved in a range of disease processes and thus have become the focus of many drug discovery programs. Widespread drug resistance to all currently used antimalarial drugs drives the search for alternative drug targets with novel mechanisms of action that offer new therapeutic options. Molecular chaperones such as heat shock proteins facilitate protein folding, play a role in protein trafficking and prevent protein misfolding in cells under stress. Heat shock protein 90 (Hsp90) is a well-studied chaperone that has been the focus of cancer drug development with moderate success. In Plasmodium falciparum (P. falciparum), heat shock proteins are thought to play a vital role in parasite survival of the physiologically diverse habitats of the parasite lifecycle and because Hsp90 is prominently expressed in P. falciparum, the chaperone is considered a potentially ideal drug target. Hsp90 function in cells is regulated by interactions with co-chaperones, which includes Heat shock protein 70-Heat shock protein 90 organising protein (Hop). As opposed to directly inhibiting Hsp90 activity, targeting Hsp90 interaction with Hop has recently been suggested as an alternative method of Hsp90 inhibition that has not been explored in P. falciparum. The aim of this research project was to demonstrate PfHsp90 and PfHop robustly interact in vitro and to facilitate high-throughput screening of PfHsp90-PfHop inhibitors by developing and optimising a novel plate capture Hsp90-Hop interaction assay. To establish the assay, the respective domains of the proteins that mediate Hsp90-Hop interaction were used (Hsp90 C- terminal domain and Hop TPR2A domain). The human Hsp90 C-terminal domain and glutathione-S-transferase (GST) coding sequences were cloned into pET-28a(+) and murine and P. falciparum TPR2A sequences into pGEX-4T-1 plasmids to enable expression of histidine-tagged and GST fusion proteins, respectively, in Escherichia coli. The P. falciparum Hsp90 C-terminal domain sequence cloned into pET-28a(+) was supplied by GenScript. The constructs were transformed into T7 Express lysYcompetent E. coli cells and subsequent small- scale expression studies showed the recombinant proteins were expressed in a soluble form allowing for subsequent protein purification. Purification of the recombinant proteins was achieved using nickel-NTA and glutathione affinity chromatography for the His-tagged (Hsp90 C-terminal domains and GST) and GST fusion proteins (TPR2A domains), respectively. The purified proteins were used to establish and optimise mammalian and P. falciparum Hsp90- Hop interaction assays on nickel-coated plates by immobilising the His-tagged C-terminal domains on the plates and detecting the binding of the GST-TPR2A domains using a colorimetric GST enzyme assay. Z’-factor values above 0.5 were observed for both assays indicating good separation between the protein interaction signals and negative control background signals, although relatively high background signals were observed for the mammalian interaction due to non-specific binding of murine TPR2A to the plate. Designed human and P. falciparum TPR peptides were observed to be effective inhibitors of the mammalian and P. falciparum interactions, demonstrating the assay’s ability to respond to inhibitor compounds. Comparison of assay performance using GST assay kit reagents and lab- prepared reagents showed the assay was more efficient using lab-prepared reagents, however, lower GST signals were observed when comparing assay performance using a custom prepared Ni-NTA plate to a purchased Ni-NTA plate. The Hsp90-Hop interaction assays were also performed using an alternative assay format in which the GST-TPR2A fusion proteins were immobilised on glutathione-coated plates and binding of the His-tagged C-terminal domains detected with a nickel-horseradish peroxidase (HRP) conjugate and a colorimetric HRP substrate. The assay showed higher interaction signals for the P. falciparum proteins but comparatively low signals for the mammalian proteins. Z’-factor values for the assay were above 0.8 for both protein sets, suggesting this assay format is superior to the GST assay. However, further optimisation of this assay format is required. This study demonstrated direct binding of PfHsp90-PfHop in vitro and established a novel and robust PfHsp90-PfHop interaction assay format that can be used in future screening campaigns.
- Full Text:
- Date Issued: 2018
Maputo declaration on the textiles, clothing and leather industries
- Authors: Worker representatives
- Date: 1999?
- Subjects: Clothing trade , Textile industry , Leather industry and trade , Complaints (Civil procedure)
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/76004 , vital:30491
- Description: The massive job losses and factory closures in the clothing, textiles and leather industries in almost all countries in the region. The low wages that continue in our industries, resulting in a low and, in many instances, declining standard of living of workers. The crisis which face unemployed workers who have no income, no social security net, and no immediate prospect of a job. It is a fundamental responsibility of governments in the region to work with trade unions and employers in order to develop appropriate policies to secure a future for the industries and to improve the conditions of workers.
- Full Text:
- Date Issued: 1999?
- Authors: Worker representatives
- Date: 1999?
- Subjects: Clothing trade , Textile industry , Leather industry and trade , Complaints (Civil procedure)
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/76004 , vital:30491
- Description: The massive job losses and factory closures in the clothing, textiles and leather industries in almost all countries in the region. The low wages that continue in our industries, resulting in a low and, in many instances, declining standard of living of workers. The crisis which face unemployed workers who have no income, no social security net, and no immediate prospect of a job. It is a fundamental responsibility of governments in the region to work with trade unions and employers in order to develop appropriate policies to secure a future for the industries and to improve the conditions of workers.
- Full Text:
- Date Issued: 1999?
Lattice-valued continuous convergence is induced by a lattice-valued uniform convergence structure
- Authors: Jäger, Gunter
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6824 , http://hdl.handle.net/10962/d1012332
- Description: We define a stratified L-uniform convergence structure on the set of all continuous mappings from a stratified L-limit space to a stratified L-uniform convergence space. This structure induces L-continuous convergence. This shows that the category of all L-limit-uniformizable spaces is cartesian closed.
- Full Text:
- Date Issued: 2006
- Authors: Jäger, Gunter
- Date: 2006
- Language: English
- Type: text , Article
- Identifier: vital:6824 , http://hdl.handle.net/10962/d1012332
- Description: We define a stratified L-uniform convergence structure on the set of all continuous mappings from a stratified L-limit space to a stratified L-uniform convergence space. This structure induces L-continuous convergence. This shows that the category of all L-limit-uniformizable spaces is cartesian closed.
- Full Text:
- Date Issued: 2006
Academic literacy in management education
- Pearse, Noel J, Amos, Trevor L
- Authors: Pearse, Noel J , Amos, Trevor L
- Date: 2000
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/270065 , vital:54392 , xlink:href="https://hdl.handle.net/10520/EJC36783"
- Description: Although management education aims to equip students with relevant knowledge, skills and competencies, making explicit and developing the cognitive thought processes necessary for management students to deal effectively with the current and future demands of the world of work, have been neglected. This article argues for the development of "complicated understanding" (Bartunek, Gordon and Weathersby 1983) in management students, through cultivating academic literacy. Using mediation, reflective inquiry and reflective writing interactively, it is illustrated how academic literacy could be promoted at the post-graduate level.
- Full Text:
- Date Issued: 2000
- Authors: Pearse, Noel J , Amos, Trevor L
- Date: 2000
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/270065 , vital:54392 , xlink:href="https://hdl.handle.net/10520/EJC36783"
- Description: Although management education aims to equip students with relevant knowledge, skills and competencies, making explicit and developing the cognitive thought processes necessary for management students to deal effectively with the current and future demands of the world of work, have been neglected. This article argues for the development of "complicated understanding" (Bartunek, Gordon and Weathersby 1983) in management students, through cultivating academic literacy. Using mediation, reflective inquiry and reflective writing interactively, it is illustrated how academic literacy could be promoted at the post-graduate level.
- Full Text:
- Date Issued: 2000
An assessment of the nutritional status of young black school children in the Albany Magisterial District, Eastern Cape
- Authors: Fincham, Robert John
- Date: 1981
- Subjects: Schools -- South Africa -- Grahamstown Africans -- Nutrition Nutrition surveys -- South Africa -- Eastern Cape Malnutrition -- South Africa -- Eastern Cape Children -- South Africa -- Nutrition
- Language: English
- Type: Book , Text
- Identifier: http://hdl.handle.net/10962/2172 , vital:20262 , ISBN 0868100773
- Description: This working paper covers a survey conducted between 16 and 30 January 1980 of 3 171 black Sub A and Sub B pupils 8 years old or younger, at schools in both the rural and urban areas of the Albany Magisterial District, Eastern Cape. The survey, under the auspices of the Institute of Social and Economic Research (ISER), Rhodes University, was carried out as a result of a request from Dr J. D. Krynauw, Regional Director of Health Services in the Eastern Cape, to assess levels of nutrition of black children. Newspaper reports (see Appendix 1) of low levels of nutrition and high infant mortality rates among young black children in the Eastern Cape appeared to suggest a chronic nutritional situation, a situation not perceived as such by the Department of Health. A comprehensive pilot study was instituted on written request from Dr Krynauw in late October 1979. A report of the pilot study findings was presented in May 1980 to the Department of Health (Fincham, 1980). The present paper elaborates on that report and also includes analyses of data not presented before. , Digitised by Rhodes University Library on behalf of the Institute of Social and Economic Research (ISER)
- Full Text:
- Date Issued: 1981
- Authors: Fincham, Robert John
- Date: 1981
- Subjects: Schools -- South Africa -- Grahamstown Africans -- Nutrition Nutrition surveys -- South Africa -- Eastern Cape Malnutrition -- South Africa -- Eastern Cape Children -- South Africa -- Nutrition
- Language: English
- Type: Book , Text
- Identifier: http://hdl.handle.net/10962/2172 , vital:20262 , ISBN 0868100773
- Description: This working paper covers a survey conducted between 16 and 30 January 1980 of 3 171 black Sub A and Sub B pupils 8 years old or younger, at schools in both the rural and urban areas of the Albany Magisterial District, Eastern Cape. The survey, under the auspices of the Institute of Social and Economic Research (ISER), Rhodes University, was carried out as a result of a request from Dr J. D. Krynauw, Regional Director of Health Services in the Eastern Cape, to assess levels of nutrition of black children. Newspaper reports (see Appendix 1) of low levels of nutrition and high infant mortality rates among young black children in the Eastern Cape appeared to suggest a chronic nutritional situation, a situation not perceived as such by the Department of Health. A comprehensive pilot study was instituted on written request from Dr Krynauw in late October 1979. A report of the pilot study findings was presented in May 1980 to the Department of Health (Fincham, 1980). The present paper elaborates on that report and also includes analyses of data not presented before. , Digitised by Rhodes University Library on behalf of the Institute of Social and Economic Research (ISER)
- Full Text:
- Date Issued: 1981
Equiprime near-rings
- Authors: Mogae, Kabelo
- Date: 2008
- Subjects: Near-rings
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:10505 , http://hdl.handle.net/10948/1028 , Near-rings
- Description: Prior to 1990, the only well known ideal-hereditary Kurosh-Amitsur radicals in the variety of zero-symmetric near-rings were the Jacobson type radicals Iv(N) , where ∨∈{2,3} and the Brown-McCoy radical. In 1990, Booth, Groenewald and Veldsman introduced the concept of an equiprime near-ring which leads to an ideal-hereditary Kurosh-Amitsur radical in N∘. The concept of an equiprime near-ring generalizes the concept of a prime ring to near-rings. Although the search for more ideal-hereditary radicals of near-rings was apparently the original motivation for the introduction of equiprime near-rings, it became clear that these near-rings are interesting in their own right. It is our aim in this treatise to give an exposition of the many interesting properties of equiprime near-rings. We begin with a brief reminder of near-ring rudiments; giving basic definitions and elementary results which are necessary for understanding and development of subsequent chapters. With the basics out of the way, our main task begins with a consideration of equiprime, strongly and completely equiprime left ideals. It is noted that any zero-symmetric near-ring can be embedded in an equiprime near-ring. Moreover, the class of equiprime near-rings is shown to be hereditary. Open questions arising out of the study of equiprime near-rings are highlighted along the way. In Chapter 3 we consider well known examples of near-rings and determine when such near-rings are equiprime. This provides more insight into the nature of equiprime near-rings and is a fertile ground for the birth of examples and counterexamples which may be used to close or solve some open question within the literature. We also prove some results which generalize some results of Booth and Hall [10] and Veldsman [29]. These results have not been previously presented elsewhere to the best of our knowledge. vii In Chapter 4, the equiprime near-rings are shown to yield an ideal-hereditary radical in N∘. It is shown that a special radical theory can be built on the equiprime nearrings in much the same way prime rings are used in ring theory to define special radical classes of rings.
- Full Text:
- Date Issued: 2008
- Authors: Mogae, Kabelo
- Date: 2008
- Subjects: Near-rings
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:10505 , http://hdl.handle.net/10948/1028 , Near-rings
- Description: Prior to 1990, the only well known ideal-hereditary Kurosh-Amitsur radicals in the variety of zero-symmetric near-rings were the Jacobson type radicals Iv(N) , where ∨∈{2,3} and the Brown-McCoy radical. In 1990, Booth, Groenewald and Veldsman introduced the concept of an equiprime near-ring which leads to an ideal-hereditary Kurosh-Amitsur radical in N∘. The concept of an equiprime near-ring generalizes the concept of a prime ring to near-rings. Although the search for more ideal-hereditary radicals of near-rings was apparently the original motivation for the introduction of equiprime near-rings, it became clear that these near-rings are interesting in their own right. It is our aim in this treatise to give an exposition of the many interesting properties of equiprime near-rings. We begin with a brief reminder of near-ring rudiments; giving basic definitions and elementary results which are necessary for understanding and development of subsequent chapters. With the basics out of the way, our main task begins with a consideration of equiprime, strongly and completely equiprime left ideals. It is noted that any zero-symmetric near-ring can be embedded in an equiprime near-ring. Moreover, the class of equiprime near-rings is shown to be hereditary. Open questions arising out of the study of equiprime near-rings are highlighted along the way. In Chapter 3 we consider well known examples of near-rings and determine when such near-rings are equiprime. This provides more insight into the nature of equiprime near-rings and is a fertile ground for the birth of examples and counterexamples which may be used to close or solve some open question within the literature. We also prove some results which generalize some results of Booth and Hall [10] and Veldsman [29]. These results have not been previously presented elsewhere to the best of our knowledge. vii In Chapter 4, the equiprime near-rings are shown to yield an ideal-hereditary radical in N∘. It is shown that a special radical theory can be built on the equiprime nearrings in much the same way prime rings are used in ring theory to define special radical classes of rings.
- Full Text:
- Date Issued: 2008
On the Wiener index of bicyclic graphs and graphs with fixed segment sequence
- Authors: Xhanti, Sinoxolo
- Date: 2021-10-29
- Subjects: Graph theory , Chemistry Mathematics , Chemistry Graphic methods , Wiener index , Bicyclic graphs , Fixed segment sequence , Degree sequence , Circumference , Core
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/190700 , vital:45019
- Description: Wiener index is defined as the sum of the distances between all unordered pairs of vertices in a graph. The study of the Wiener index is motivated by its application in chemistry. This thesis focuses on finding extremal bicyclic graphs relative to Wiener index under various conditions such as fixed circumference (length of the longest cycle) or fixed size of the core (maximal subgraph with no degree less than 2). A segment of a graph G is either a path whose end vertices have degree 1 or at least 3 in G and all the internal vertices have degree 2 in G, or a cycle where all the vertices have degree 2 in G except possibly one. The lengths of all the segments of G form it segment sequence. We also discuss extremal graphs with given segment sequence. , Thesis (MSc) -- Faculty of Science, Mathematics, 2021
- Full Text:
- Date Issued: 2021-10-29
- Authors: Xhanti, Sinoxolo
- Date: 2021-10-29
- Subjects: Graph theory , Chemistry Mathematics , Chemistry Graphic methods , Wiener index , Bicyclic graphs , Fixed segment sequence , Degree sequence , Circumference , Core
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/190700 , vital:45019
- Description: Wiener index is defined as the sum of the distances between all unordered pairs of vertices in a graph. The study of the Wiener index is motivated by its application in chemistry. This thesis focuses on finding extremal bicyclic graphs relative to Wiener index under various conditions such as fixed circumference (length of the longest cycle) or fixed size of the core (maximal subgraph with no degree less than 2). A segment of a graph G is either a path whose end vertices have degree 1 or at least 3 in G and all the internal vertices have degree 2 in G, or a cycle where all the vertices have degree 2 in G except possibly one. The lengths of all the segments of G form it segment sequence. We also discuss extremal graphs with given segment sequence. , Thesis (MSc) -- Faculty of Science, Mathematics, 2021
- Full Text:
- Date Issued: 2021-10-29
Ngabatoke tulengoma inde pazilonga
- Men and Women at Chief Chiwala's Village, Composer not specified, Tracey, Hugh
- Authors: Men and Women at Chief Chiwala's Village , Composer not specified , Tracey, Hugh
- Date: 1949-08-14
- Subjects: Folk music--Africa , Field recordings , Africa, Sub-Saharan , Africa Zambia Not specified f-za
- Language: Yao
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/208218 , vital:47245 , International Library of African Music, Rhodes University, Makhanda, South Africa , Hugh Tracey Field Tapes, Rhodes University, Makhanda, South Africa , HTFT076-C92 , Research no. C4G16
- Description: Not Specified.
- Full Text: false
- Date Issued: 1949-08-14
- Authors: Men and Women at Chief Chiwala's Village , Composer not specified , Tracey, Hugh
- Date: 1949-08-14
- Subjects: Folk music--Africa , Field recordings , Africa, Sub-Saharan , Africa Zambia Not specified f-za
- Language: Yao
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/208218 , vital:47245 , International Library of African Music, Rhodes University, Makhanda, South Africa , Hugh Tracey Field Tapes, Rhodes University, Makhanda, South Africa , HTFT076-C92 , Research no. C4G16
- Description: Not Specified.
- Full Text: false
- Date Issued: 1949-08-14
Code of Conduct for Australian companies with interests in the Republic of South Africa
- Date: Mar 1987
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/118204 , vital:34607
- Description: This is the first report under the voluntary Code of Conduct for Australian companies in South Africa. It marks Australia's entry into an area of monitoring and public reporting where the United States of America, the European Community (particularly the United Kingdom) and Canada have had Codes of Conduct since 1976 to 1978. Each of the countries concerned has companies with investment in South Africa and a physical presence there - through subsidiaries that operate as part of South African industry and that employ South African workers, including black workers. The Codes are intended to secure that companies from outside South Africa do not, when employing non-white (and particularly black) workers in South Africa, exploit the apartheid system. On the contrary, the objective is to work towards the elimination of discrimination at the industrial level - in pay rates, opportunities and otherwise - and at the same time to try to imp rove the position of the employees outside the work place. Those who press for stronger sanctions against South Africa and for active disinvestment policies criticise the Codes as weak palliatives for apartheid. In past years that might have been charged more forcibly. Today the existence of the Codes does not seem to be affecting decisions on sanctions. And the converse also seems to be true; with the sanctions that are presently operating the Codes continue to operate. Of course, when companies do disinvest, the Codes have fewer companies to cover and could eventually wither on that account. To the extent, therefore, that the Codes operate on the fact of foreign companies being in South Africa, they could be thought inconsistent with any policy of rapid disinvestment. However, there are at present no such policies operating at the level of Governments. A question arising from that is whether foreign companies, if they do remain in South Africa, should be subject to Codes and to reports back home as to their conduct, it being recognised that those reports, depending on their content and their reception, may either quieten or stir pressures for further disinvestment.
- Full Text:
- Date Issued: Mar 1987
- Date: Mar 1987
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/118204 , vital:34607
- Description: This is the first report under the voluntary Code of Conduct for Australian companies in South Africa. It marks Australia's entry into an area of monitoring and public reporting where the United States of America, the European Community (particularly the United Kingdom) and Canada have had Codes of Conduct since 1976 to 1978. Each of the countries concerned has companies with investment in South Africa and a physical presence there - through subsidiaries that operate as part of South African industry and that employ South African workers, including black workers. The Codes are intended to secure that companies from outside South Africa do not, when employing non-white (and particularly black) workers in South Africa, exploit the apartheid system. On the contrary, the objective is to work towards the elimination of discrimination at the industrial level - in pay rates, opportunities and otherwise - and at the same time to try to imp rove the position of the employees outside the work place. Those who press for stronger sanctions against South Africa and for active disinvestment policies criticise the Codes as weak palliatives for apartheid. In past years that might have been charged more forcibly. Today the existence of the Codes does not seem to be affecting decisions on sanctions. And the converse also seems to be true; with the sanctions that are presently operating the Codes continue to operate. Of course, when companies do disinvest, the Codes have fewer companies to cover and could eventually wither on that account. To the extent, therefore, that the Codes operate on the fact of foreign companies being in South Africa, they could be thought inconsistent with any policy of rapid disinvestment. However, there are at present no such policies operating at the level of Governments. A question arising from that is whether foreign companies, if they do remain in South Africa, should be subject to Codes and to reports back home as to their conduct, it being recognised that those reports, depending on their content and their reception, may either quieten or stir pressures for further disinvestment.
- Full Text:
- Date Issued: Mar 1987
A multi-threading software countermeasure to mitigate side channel analysis in the time domain
- Authors: Frieslaar, Ibraheem
- Date: 2019
- Subjects: Computer security , Data encryption (Computer science) , Noise generators (Electronics)
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/71152 , vital:29790
- Description: This research is the first of its kind to investigate the utilisation of a multi-threading software-based countermeasure to mitigate Side Channel Analysis (SCA) attacks, with a particular focus on the AES-128 cryptographic algorithm. This investigation is novel, as there has not been a software-based countermeasure relying on multi-threading to our knowledge. The research has been tested on the Atmel microcontrollers, as well as a more fully featured system in the form of the popular Raspberry Pi that utilises the ARM7 processor. The main contributions of this research is the introduction of a multi-threading software based countermeasure used to mitigate SCA attacks on both an embedded device and a Raspberry Pi. These threads are comprised of various mathematical operations which are utilised to generate electromagnetic (EM) noise resulting in the obfuscation of the execution of the AES-128 algorithm. A novel EM noise generator known as the FRIES noise generator is implemented to obfuscate data captured in the EM field. FRIES comprises of hiding the execution of AES-128 algorithm within the EM noise generated by the 512 Secure Hash Algorithm (SHA) from the libcrypto++ and OpenSSL libraries. In order to evaluate the proposed countermeasure, a novel attack methodology was developed where the entire secret AES-128 encryption key was recovered from a Raspberry Pi, which has not been achieved before. The FRIES noise generator was pitted against this new attack vector and other known noise generators. The results exhibited that the FRIES noise generator withstood this attack whilst other existing techniques still leaked out secret information. The visual location of the AES-128 encryption algorithm in the EM spectrum and key recovery was prevented. These results demonstrated that the proposed multi-threading software based countermeasure was able to be resistant to existing and new forms of attacks, thus verifying that a multi-threading software based countermeasure can serve to mitigate SCA attacks.
- Full Text:
- Date Issued: 2019
- Authors: Frieslaar, Ibraheem
- Date: 2019
- Subjects: Computer security , Data encryption (Computer science) , Noise generators (Electronics)
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/71152 , vital:29790
- Description: This research is the first of its kind to investigate the utilisation of a multi-threading software-based countermeasure to mitigate Side Channel Analysis (SCA) attacks, with a particular focus on the AES-128 cryptographic algorithm. This investigation is novel, as there has not been a software-based countermeasure relying on multi-threading to our knowledge. The research has been tested on the Atmel microcontrollers, as well as a more fully featured system in the form of the popular Raspberry Pi that utilises the ARM7 processor. The main contributions of this research is the introduction of a multi-threading software based countermeasure used to mitigate SCA attacks on both an embedded device and a Raspberry Pi. These threads are comprised of various mathematical operations which are utilised to generate electromagnetic (EM) noise resulting in the obfuscation of the execution of the AES-128 algorithm. A novel EM noise generator known as the FRIES noise generator is implemented to obfuscate data captured in the EM field. FRIES comprises of hiding the execution of AES-128 algorithm within the EM noise generated by the 512 Secure Hash Algorithm (SHA) from the libcrypto++ and OpenSSL libraries. In order to evaluate the proposed countermeasure, a novel attack methodology was developed where the entire secret AES-128 encryption key was recovered from a Raspberry Pi, which has not been achieved before. The FRIES noise generator was pitted against this new attack vector and other known noise generators. The results exhibited that the FRIES noise generator withstood this attack whilst other existing techniques still leaked out secret information. The visual location of the AES-128 encryption algorithm in the EM spectrum and key recovery was prevented. These results demonstrated that the proposed multi-threading software based countermeasure was able to be resistant to existing and new forms of attacks, thus verifying that a multi-threading software based countermeasure can serve to mitigate SCA attacks.
- Full Text:
- Date Issued: 2019
3-Methyl-1-phenyl-4-[(phenyl)(2-phenylhydrazin-1-yl)methylidene]-1H-pyrazol-5(4H)-one
- Identifier: http://vital.seals.ac.za8080/10353/7489 , http://hdl.handle.net/10353/5328 , vital:29192
- Full Text:
- Identifier: http://vital.seals.ac.za8080/10353/7489 , http://hdl.handle.net/10353/5328 , vital:29192
- Full Text:
Synthesis, characterization, and biological studies of pyrazolone Schiff bases and their transition metal complexes
- Authors: Idemudia, Omoruyi Gold
- Date: 2014
- Language: English
- Type: Thesis , Doctoral , PhD (Chemistry)
- Identifier: vital:11340 , http://hdl.handle.net/10353/d1016068
- Description: Some new acylpyrazolone Schiff bases have been synthesized from the condensation reaction of two acylpyrazolone diketone precursors with phenylhydrazine, 2,4-dinitrophenylhydrazine and sulfanilamide. They have been fully characterized by elemental analysis and spectroscopic techniques (IR,1H and 13C NMR, and mass-spectra). The single crystal structure of the benzoyl derivative acylpyrazolone Schiff bases have been obtained and analyzed by X-ray crystallography technique. Solid state X-ray diffraction revealed a keto tautomer Schiff base in solid state. Mn(II), Co(II), Ni(II) and Cu(II) complexes with the Schiff bases have been synthesized and characterized by elemental analysis, IR and UV-VIS spectroscopy, magnetic susceptibility measurements, and thermal studies (TGA and DTG). An octahedral geometry around the transition metal ion, consisting of two bidentate Schiff base ligands bonding through the azometine nitrogen and ketonic oxygen have been proposed based on careful interpretation of available analytical and spectroscopic characterization results. Two water molecules as ligands complete the octahedral geometry in all cases. Using the invitro disc diffusion method for screening synthesized compounds against selected gram positive and gram negative bacterial at 40 mg/mL, and the DPPH free radical scavenging methods at 0.50, 0.25 and 0.13 mg/mL, the synthesized Schiff base and metal complexes showed varying biological activities. 4-benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one sul29 fanilamide showed more activity generally, exhibiting a broad spectrum activity against all selected bacterial in some cases. Mn(II), Co(II) and Ni(II) complexes of sulfanilamide Schiff base with the acetylpyrazolone derivative 4-acetyl-3-methyl-1-phenyl-2-pyrazolin-5-one sulfanilamide, exhibited a stronger and very good DPPH radical scavenging activity as good as ascorbic acid on comparing, but not with Cu(II). As such they could be important antitumour candidates.
- Full Text:
- Date Issued: 2014
- Authors: Idemudia, Omoruyi Gold
- Date: 2014
- Language: English
- Type: Thesis , Doctoral , PhD (Chemistry)
- Identifier: vital:11340 , http://hdl.handle.net/10353/d1016068
- Description: Some new acylpyrazolone Schiff bases have been synthesized from the condensation reaction of two acylpyrazolone diketone precursors with phenylhydrazine, 2,4-dinitrophenylhydrazine and sulfanilamide. They have been fully characterized by elemental analysis and spectroscopic techniques (IR,1H and 13C NMR, and mass-spectra). The single crystal structure of the benzoyl derivative acylpyrazolone Schiff bases have been obtained and analyzed by X-ray crystallography technique. Solid state X-ray diffraction revealed a keto tautomer Schiff base in solid state. Mn(II), Co(II), Ni(II) and Cu(II) complexes with the Schiff bases have been synthesized and characterized by elemental analysis, IR and UV-VIS spectroscopy, magnetic susceptibility measurements, and thermal studies (TGA and DTG). An octahedral geometry around the transition metal ion, consisting of two bidentate Schiff base ligands bonding through the azometine nitrogen and ketonic oxygen have been proposed based on careful interpretation of available analytical and spectroscopic characterization results. Two water molecules as ligands complete the octahedral geometry in all cases. Using the invitro disc diffusion method for screening synthesized compounds against selected gram positive and gram negative bacterial at 40 mg/mL, and the DPPH free radical scavenging methods at 0.50, 0.25 and 0.13 mg/mL, the synthesized Schiff base and metal complexes showed varying biological activities. 4-benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one sul29 fanilamide showed more activity generally, exhibiting a broad spectrum activity against all selected bacterial in some cases. Mn(II), Co(II) and Ni(II) complexes of sulfanilamide Schiff base with the acetylpyrazolone derivative 4-acetyl-3-methyl-1-phenyl-2-pyrazolin-5-one sulfanilamide, exhibited a stronger and very good DPPH radical scavenging activity as good as ascorbic acid on comparing, but not with Cu(II). As such they could be important antitumour candidates.
- Full Text:
- Date Issued: 2014
From frontier to midlands: a history of the Graaff-Reinet district, 1786-1910
- Authors: Smith, Kenneth Wyndham
- Date: 1976
- Subjects: Graaff-Reinet (South Africa) -- History
- Language: English
- Type: Book , Text
- Identifier: http://hdl.handle.net/10962/2656 , vital:20313 , ISBN 0949980730
- Description: The study of local history in South Africa is still in its infancy and has not been accorded the same recognition as elsewhere. There is no convenient manual to guide the would-be local historian of the Cape. There are few models that provide an insight into the main problems encountered by the local historian of a Cape community. In such local histories as exist, attention has been focussed predominantly on the foundation and physical growth of towns, the naming of streets, the establishment of schools and hospitals. Many of these accounts were written for publicity purposes or to commemorate the founding of towns. Although there is no history of the Dutch Reformed Church in Graaff-Reinet, the history of local congregations of the Dutch Reformed Church has generally been well covered in the form of Gedenkboeke and other studies. These frequently have a particular relevance as many towns such as Burgersdorp and Colesberg were founded as a result of the initiative of the church. Preface. , Digitised by Rhodes University Library on behalf of the Institute of Social and Economic Research (ISER)
- Full Text:
- Date Issued: 1976
- Authors: Smith, Kenneth Wyndham
- Date: 1976
- Subjects: Graaff-Reinet (South Africa) -- History
- Language: English
- Type: Book , Text
- Identifier: http://hdl.handle.net/10962/2656 , vital:20313 , ISBN 0949980730
- Description: The study of local history in South Africa is still in its infancy and has not been accorded the same recognition as elsewhere. There is no convenient manual to guide the would-be local historian of the Cape. There are few models that provide an insight into the main problems encountered by the local historian of a Cape community. In such local histories as exist, attention has been focussed predominantly on the foundation and physical growth of towns, the naming of streets, the establishment of schools and hospitals. Many of these accounts were written for publicity purposes or to commemorate the founding of towns. Although there is no history of the Dutch Reformed Church in Graaff-Reinet, the history of local congregations of the Dutch Reformed Church has generally been well covered in the form of Gedenkboeke and other studies. These frequently have a particular relevance as many towns such as Burgersdorp and Colesberg were founded as a result of the initiative of the church. Preface. , Digitised by Rhodes University Library on behalf of the Institute of Social and Economic Research (ISER)
- Full Text:
- Date Issued: 1976
Structural analysis of proteases from South African HIV-1 (subtype C) patients undergoing Lopinavir treatment, using comparative modeling, ligand-docking and molecular dynamics
- Authors: Sheik-Amamuddy, Olivier
- Date: 2017
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/4931 , vital:20744
- Description: HIV is regarded as one of the most devastating infectious diseases of the last few decades, and has a high prevalence in South Africa, subtype C being the most common. Palliative measures used to fight HIV involve the use various types of inhibitors, including the use of HIV protease inhibitors. Representatives from this class of inhibitors are gradually losing their efficacy due to development of resistance mutations from HIV-1. In this study, compounds from the South African Natural Compound Database (SANCDB) were screened against HIV-1 protease models generated from protease protein sequences belonging to 11 South African HIV patients before and after treatment with Lopinavir. The effect of Lopinavir on the alteration of drug-binding affinity before and after treatment is investigated by molecular docking of the protease against other FDA-approved drugs and detection of mutation types using the HIVdb tool. A network representation of hydrogen bonding between docked ligands and their receptor proteases has been developed and a profiling method of visualizing receptor-ligand docking energies at the local level is presented. Four potential HIV-1 protease inhibitors were identified from the list of 599 natural compounds on the basis of receptor conformation and binding free energy. Ligand stabilities were monitored by 20ns molecular dynamics runs using the GROMACS software.
- Full Text:
- Date Issued: 2017
- Authors: Sheik-Amamuddy, Olivier
- Date: 2017
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/4931 , vital:20744
- Description: HIV is regarded as one of the most devastating infectious diseases of the last few decades, and has a high prevalence in South Africa, subtype C being the most common. Palliative measures used to fight HIV involve the use various types of inhibitors, including the use of HIV protease inhibitors. Representatives from this class of inhibitors are gradually losing their efficacy due to development of resistance mutations from HIV-1. In this study, compounds from the South African Natural Compound Database (SANCDB) were screened against HIV-1 protease models generated from protease protein sequences belonging to 11 South African HIV patients before and after treatment with Lopinavir. The effect of Lopinavir on the alteration of drug-binding affinity before and after treatment is investigated by molecular docking of the protease against other FDA-approved drugs and detection of mutation types using the HIVdb tool. A network representation of hydrogen bonding between docked ligands and their receptor proteases has been developed and a profiling method of visualizing receptor-ligand docking energies at the local level is presented. Four potential HIV-1 protease inhibitors were identified from the list of 599 natural compounds on the basis of receptor conformation and binding free energy. Ligand stabilities were monitored by 20ns molecular dynamics runs using the GROMACS software.
- Full Text:
- Date Issued: 2017
Predikant and priest : some Calvinist and Catholic role profiles of the religious functionary in South Africa : a comment and review of two empirical studies
- Authors: Higgins, Edward
- Date: 1972
- Subjects: Clergy -- South Africa , Clergy -- Office
- Language: English
- Type: Book , text
- Identifier: vital:551 , http://hdl.handle.net/10962/d1020578
- Description: A revised English version of "Les roles religieux dans le contexte multi-racial sud-africain : le profil du ministere dans le calvinisme et le catholicisme"
- Full Text:
- Date Issued: 1972
- Authors: Higgins, Edward
- Date: 1972
- Subjects: Clergy -- South Africa , Clergy -- Office
- Language: English
- Type: Book , text
- Identifier: vital:551 , http://hdl.handle.net/10962/d1020578
- Description: A revised English version of "Les roles religieux dans le contexte multi-racial sud-africain : le profil du ministere dans le calvinisme et le catholicisme"
- Full Text:
- Date Issued: 1972
A socio-economic survey of the Amatola Basin: interim report
- Bekker, S B, de Wet, Christopher J, Manona, Cecil W
- Authors: Bekker, S B , de Wet, Christopher J , Manona, Cecil W
- Date: 1981
- Subjects: Ciskei (South Africa) -- Rural conditions Agriculture -- South Africa -- Ciskei Middledrift (South Africa) Fingo (African people) Hlubi (African people) Agriculture -- South Africa -- Ciskei Amatola River Watershed (South Africa) -- Economic conditions Amatola River Watershed (South Africa) -- Social conditions
- Language: English
- Type: Book , Text
- Identifier: http://hdl.handle.net/10962/2282 , vital:20272 , ISBN 0868100730
- Description: Early in 1981, Professor S. Bekker of Rhodes University was invited to attend a meeting of the Amatola Basin Steering Committee of the Agricultural and Rural Development Research Institute (ARDRI) at the University of Fort Hare. At this meeting, Professor Bekker was invited to undertake a socio-economic survey of the Amatola Basin. The Board of the Institute of Social and Economic Research at Rhodes University gave Professor Bekker permission in February 1981 to undertake the research project on condition that it was conducted in the fashion this Institute usually requires. It was subsequently agreed that the survey, known as 'Amatola Basin VII: Socio-economic survey', was to establish the basic demographic, kinship, consumption and employment patterns of the residents of the Amatola Basin. Practices and traditions related to dry land agriculture would also be identified , Digitised by Rhodes University Library on behalf of the Institute of Social and Economic Research (ISER)
- Full Text:
- Date Issued: 1981
- Authors: Bekker, S B , de Wet, Christopher J , Manona, Cecil W
- Date: 1981
- Subjects: Ciskei (South Africa) -- Rural conditions Agriculture -- South Africa -- Ciskei Middledrift (South Africa) Fingo (African people) Hlubi (African people) Agriculture -- South Africa -- Ciskei Amatola River Watershed (South Africa) -- Economic conditions Amatola River Watershed (South Africa) -- Social conditions
- Language: English
- Type: Book , Text
- Identifier: http://hdl.handle.net/10962/2282 , vital:20272 , ISBN 0868100730
- Description: Early in 1981, Professor S. Bekker of Rhodes University was invited to attend a meeting of the Amatola Basin Steering Committee of the Agricultural and Rural Development Research Institute (ARDRI) at the University of Fort Hare. At this meeting, Professor Bekker was invited to undertake a socio-economic survey of the Amatola Basin. The Board of the Institute of Social and Economic Research at Rhodes University gave Professor Bekker permission in February 1981 to undertake the research project on condition that it was conducted in the fashion this Institute usually requires. It was subsequently agreed that the survey, known as 'Amatola Basin VII: Socio-economic survey', was to establish the basic demographic, kinship, consumption and employment patterns of the residents of the Amatola Basin. Practices and traditions related to dry land agriculture would also be identified , Digitised by Rhodes University Library on behalf of the Institute of Social and Economic Research (ISER)
- Full Text:
- Date Issued: 1981
An evaluation of the process and impact of outsourcing information technology (IT) services by Eastern Cape Treasury Department (ECTD) to the State Information Technology Agency (SITA)
- Authors: Mdlokovi, Lulama Reuben
- Date: 2008
- Subjects: State Information Technology Agency (South Africa) Administrative agencies -- South Africa Information technology -- Management Technology -- Information services Information services industry Telecommunication Value-added networks (Computer networks)
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:743 , http://hdl.handle.net/10962/d1003864
- Description: The aim of this research is to evaluate the process and impact of outsourcing information technology (IT) services of Eastern Cape Treasury Department (ECTD) to State Information Technology Agency (SITA). This research study has been prompted by the fact that the South African Government through the National Department of Public Service and Administration has established SITA with a sole purpose of improving service delivery by all national, provincial and local government departments. The researcher’s concern is whether the relationship between SITA and these departments is working or not. The research paradigm adopted is a constructivist approach and the ontological position adopted assumed multiple realities. The research method used in this study is the evaluation research method. Key to the research procedure was the fact that four senior officials were interviewed using audio recording, where in two were each chosen from SITA and ECTD. The researcher used document analysis and interviews as a means of collecting data. Separate open-ended questions for SITA and ECTD were structured in such a way that it would be easy to extract themes describing the details of a particular question. The researcher made use of thematic analysis. The theory drive-code development process was key in the research analysis. ECTD outsourced to SITA the following IT services, namely, provision or maintenance of a private telecommunication network (PTN) or a value-added network (VAN); transversal information systems and its data-processing or associated services; training in IT/IS; application software development; maintenance services for IT software or infrastructure; data-processing or associated services for specific IT applications or systems such as website development; and IT support. The interviewed officials from ECTD contend that they used the SCM Guide and SITA ACT when pursuing IT outsourcing for projects such as those listed above. One of the key projects outsourced to SITA is the IFMS, which is a project programme of the National Treasury Department working closely with provinces (e.g. ECTD), National Department of Public Service and Administration (NDPSA) and SITA. The IFMS project has been implemented following the SCM guidelines. The key SCM Guide components are demand, acquisition, logistics, and disposal management. The engagement model used by SITA to guide them on the process of engaging in an IT outsourcing relationship has, according to the officials interviewed, been a success. SITA uses a standard contract wherein other specific contracts receive minor adjustments. The impact of IT outsourcing has shown increases in customer satisfaction improvement, transformation of government procurement and provisioning practices, appointment of Consultants, interpretation of the Preferential Procurement Policy, promotion of the consistent application of Best Practices, information systems security environment, and improving service delivery.
- Full Text:
- Date Issued: 2008
- Authors: Mdlokovi, Lulama Reuben
- Date: 2008
- Subjects: State Information Technology Agency (South Africa) Administrative agencies -- South Africa Information technology -- Management Technology -- Information services Information services industry Telecommunication Value-added networks (Computer networks)
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:743 , http://hdl.handle.net/10962/d1003864
- Description: The aim of this research is to evaluate the process and impact of outsourcing information technology (IT) services of Eastern Cape Treasury Department (ECTD) to State Information Technology Agency (SITA). This research study has been prompted by the fact that the South African Government through the National Department of Public Service and Administration has established SITA with a sole purpose of improving service delivery by all national, provincial and local government departments. The researcher’s concern is whether the relationship between SITA and these departments is working or not. The research paradigm adopted is a constructivist approach and the ontological position adopted assumed multiple realities. The research method used in this study is the evaluation research method. Key to the research procedure was the fact that four senior officials were interviewed using audio recording, where in two were each chosen from SITA and ECTD. The researcher used document analysis and interviews as a means of collecting data. Separate open-ended questions for SITA and ECTD were structured in such a way that it would be easy to extract themes describing the details of a particular question. The researcher made use of thematic analysis. The theory drive-code development process was key in the research analysis. ECTD outsourced to SITA the following IT services, namely, provision or maintenance of a private telecommunication network (PTN) or a value-added network (VAN); transversal information systems and its data-processing or associated services; training in IT/IS; application software development; maintenance services for IT software or infrastructure; data-processing or associated services for specific IT applications or systems such as website development; and IT support. The interviewed officials from ECTD contend that they used the SCM Guide and SITA ACT when pursuing IT outsourcing for projects such as those listed above. One of the key projects outsourced to SITA is the IFMS, which is a project programme of the National Treasury Department working closely with provinces (e.g. ECTD), National Department of Public Service and Administration (NDPSA) and SITA. The IFMS project has been implemented following the SCM guidelines. The key SCM Guide components are demand, acquisition, logistics, and disposal management. The engagement model used by SITA to guide them on the process of engaging in an IT outsourcing relationship has, according to the officials interviewed, been a success. SITA uses a standard contract wherein other specific contracts receive minor adjustments. The impact of IT outsourcing has shown increases in customer satisfaction improvement, transformation of government procurement and provisioning practices, appointment of Consultants, interpretation of the Preferential Procurement Policy, promotion of the consistent application of Best Practices, information systems security environment, and improving service delivery.
- Full Text:
- Date Issued: 2008