Analysis of the pre- to post- apartheid language in education policies: an investigation for multilingualism
- Authors: Zumani, Nobesutu Faith
- Date: 2019
- Subjects: Multilingual education -- South Africa , Native language and education -- South Africa Language policy -- South Africa African languages -- Social aspects
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/44235 , vital:37140
- Description: The 1997 language policy in basic education promotes multilingualism in basic, education where there is under-utilisation of African languages. The main aim of this study is to investigate the reason for the under-utilisation of African languages in basic education. Transitional bilingual education is practised (TBE) instead of developmental maintenance bilingual education (MBE). The pre and post-apartheid language- in-education policies, including the Constitution, were collected, analysed and interpreted to find out why these languages are not used for education. It was discovered that the legacy of the previous policies has had an influence on the present policy. Also, the escape clauses on the present policy, such as “practicably reasonable,” and “choose,” have an impact on non-implementation of the post-apartheid language policy. The researcher recommends the development of an implementation plan and the revision of powers for SGBs to choose languages for their schools.
- Full Text:
- Date Issued: 2019
- Authors: Zumani, Nobesutu Faith
- Date: 2019
- Subjects: Multilingual education -- South Africa , Native language and education -- South Africa Language policy -- South Africa African languages -- Social aspects
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/44235 , vital:37140
- Description: The 1997 language policy in basic education promotes multilingualism in basic, education where there is under-utilisation of African languages. The main aim of this study is to investigate the reason for the under-utilisation of African languages in basic education. Transitional bilingual education is practised (TBE) instead of developmental maintenance bilingual education (MBE). The pre and post-apartheid language- in-education policies, including the Constitution, were collected, analysed and interpreted to find out why these languages are not used for education. It was discovered that the legacy of the previous policies has had an influence on the present policy. Also, the escape clauses on the present policy, such as “practicably reasonable,” and “choose,” have an impact on non-implementation of the post-apartheid language policy. The researcher recommends the development of an implementation plan and the revision of powers for SGBs to choose languages for their schools.
- Full Text:
- Date Issued: 2019
Analyzing the Anthropogenic Allee Effect in cycad (Encephalartos species) populations in South Africa: an evaluation of illegal trade and conservation policy
- Authors: Earle, Sasha
- Date: 2019
- Subjects: Allee effect , Cycads -- Conservation -- South Africa , Botany, Economic -- South Africa , Rare plants -- South Africa , Endangered plants -- South Africa , Wild plant trade -- Law and legislation -- South Africa
- Language: English
- Type: text , Thesis , Masters , Mcom
- Identifier: http://hdl.handle.net/10962/95565 , vital:31171
- Description: South Africa is a country known for rich biodiversity and ecosystems across the land and seascape. South Africa is one of the global hotspots for cycad diversity. Cycads are known to be the world’s most threatened plant species; declining in South Africa at a rapid pace, with threat of extinction in the wild. The main factor being harvesting from the wild for private collections. Rare cycad species’ are especially sought after by collectors. Economic theory assumes that the exploitation of a species is unlikely to result in extinction due to the increasing costs of finding the last few individuals of a species. However, the theory of the Anthropogenic Allee Effect (AAE) suggests that if consumers place a disproportionate value on a rare species’, a cycle may result whereby increased exploitation decreases population size, increasing the value of the species and, consequently, leading to its extinction in the wild. This hypothesis was tested for 37 Encephalartos species using data collected on wild populations, auction prices and the IUCN Red List status for the year 2010. It was hypothesised that an AAE was present within Encephalartos species, as three species have already gone extinct in the wild. The price per centimetre was positively correlated to the rarity of the species and the price per centimetre was negatively correlated to the wild population size. The results suggest a trend of an AAE for the year 2010. Adequate conservation policies are needed to reduce the effects of demand on illegal harvesting and prevent extinction in the wild. The effect of rarity needs to be taken into account to ensure successfulness of such policies. The most recent conservation policy implemented to protect cycads in South Africa is the Strategy and Action for the Management of Cycads in South Africa, which was introduced in 2016. The successfulness of this policy cannot, however, be analysed due to a lack of census data following its implementation.
- Full Text:
- Date Issued: 2019
- Authors: Earle, Sasha
- Date: 2019
- Subjects: Allee effect , Cycads -- Conservation -- South Africa , Botany, Economic -- South Africa , Rare plants -- South Africa , Endangered plants -- South Africa , Wild plant trade -- Law and legislation -- South Africa
- Language: English
- Type: text , Thesis , Masters , Mcom
- Identifier: http://hdl.handle.net/10962/95565 , vital:31171
- Description: South Africa is a country known for rich biodiversity and ecosystems across the land and seascape. South Africa is one of the global hotspots for cycad diversity. Cycads are known to be the world’s most threatened plant species; declining in South Africa at a rapid pace, with threat of extinction in the wild. The main factor being harvesting from the wild for private collections. Rare cycad species’ are especially sought after by collectors. Economic theory assumes that the exploitation of a species is unlikely to result in extinction due to the increasing costs of finding the last few individuals of a species. However, the theory of the Anthropogenic Allee Effect (AAE) suggests that if consumers place a disproportionate value on a rare species’, a cycle may result whereby increased exploitation decreases population size, increasing the value of the species and, consequently, leading to its extinction in the wild. This hypothesis was tested for 37 Encephalartos species using data collected on wild populations, auction prices and the IUCN Red List status for the year 2010. It was hypothesised that an AAE was present within Encephalartos species, as three species have already gone extinct in the wild. The price per centimetre was positively correlated to the rarity of the species and the price per centimetre was negatively correlated to the wild population size. The results suggest a trend of an AAE for the year 2010. Adequate conservation policies are needed to reduce the effects of demand on illegal harvesting and prevent extinction in the wild. The effect of rarity needs to be taken into account to ensure successfulness of such policies. The most recent conservation policy implemented to protect cycads in South Africa is the Strategy and Action for the Management of Cycads in South Africa, which was introduced in 2016. The successfulness of this policy cannot, however, be analysed due to a lack of census data following its implementation.
- Full Text:
- Date Issued: 2019
Another world is possible: the socialist mural in Luanda as Visual Anticipation of a New Socialist Society. We travel the SpaceWay-Black Imagination, Fragments and Diffractions
- Authors: Siegert, Nadine
- Date: 2019
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/146309 , vital:38514 , ISBN 9783960915300
- Description: Book abstract. From the visual politics of the FRELIMO-liberation script in Mozambique via the brooms and spoons of Le Balai Citoyen in Burkina Faso, to the updating of images from past revolutions on Twitter and Facebook, often in the diaspora – images play a key role in the envisioning of futures and social utopia. And more than that: Revolutions, understood as moments of radical social and cultural change, are driven by images, as empirical investigations on- and offline show. But what actually constitutes the 'seismographic power' of images, and the sustainability of icons from past ruptures in terms of radicalism, such as the portraits of Burkina Faso's and Mozambiques first presidents' Thomas Sankara and Samora Machel?.
- Full Text:
- Date Issued: 2019
- Authors: Siegert, Nadine
- Date: 2019
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/146309 , vital:38514 , ISBN 9783960915300
- Description: Book abstract. From the visual politics of the FRELIMO-liberation script in Mozambique via the brooms and spoons of Le Balai Citoyen in Burkina Faso, to the updating of images from past revolutions on Twitter and Facebook, often in the diaspora – images play a key role in the envisioning of futures and social utopia. And more than that: Revolutions, understood as moments of radical social and cultural change, are driven by images, as empirical investigations on- and offline show. But what actually constitutes the 'seismographic power' of images, and the sustainability of icons from past ruptures in terms of radicalism, such as the portraits of Burkina Faso's and Mozambiques first presidents' Thomas Sankara and Samora Machel?.
- Full Text:
- Date Issued: 2019
Antecedents and influence of the union-management relationship on employee relationships in the automotive, component and metal industries in the Nelson Mandela Bay Metropole
- Authors: Bowler, Jennifer
- Date: 2019
- Subjects: Industrial relations, South Africa , Psychology, Industrial Work environment Industrial relations Labor unions
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10948/37150 , vital:34126
- Description: South Africa is consistently portrayed as having uncooperative union-management relationships which negatively impact competitiveness. However, the post-1994 labour legislation was specifically crafted with the intention of positioning the adversarial wealth distribution phase of the union-management relationship within centralised bargaining forums and promoting cooperative relationships within workplaces. The purpose of this study was to investigate whether within the South Africa context of global competitiveness, the employment relations institutions of centralised and decentralised collective bargaining, employee participation and involvement, in the context of organisational justice, have contributed to management, shop stewards and production employees developing effective1 collective and individual employment relationships positively associated with competitive individual and company performance. The targeted population were companies within the Nelson Mandela Metropolitan Area that were registered with one of the four bargaining councils, Automotive (NBF), Automotive component (MIBCO), New Tyre (NTMIBC) and Metal and Engineering (MEIBC). In addition, since the National Union of Metal Workers was the dominant union in all four of these councils, an additional criterion for potential participation was at least one NUMSA shop steward. Fourteen companies agreed to participate. In total 63 shop stewards, 82 managers and 660 production employees were surveyed using self-administered questionnaires. The results of the study identified that the three major stakeholders hold significantly different perceptions regarding the quality of the management-shop steward relationship, with management the most positive and production employees the least. Further, investigating the factors that influence the perceptions that management and shop stewards have of their relationship, it was identified that for management the most influential factor was their beliefs regarding the interdependent nature of the relationship. For the shop stewards the situation was more nuanced with beliefs regarding interdependence, the perceptions of shop steward-management climate within the bargaining council, satisfaction 1 Definition of an effective employment relationship: An effective employment relationship is one in which the parties successfully resolve issues arising from their conflicting interests and successfully pursue joint gains where they share common interests (Kochan & Katz, 1988) with bargaining council agreements and workplace human resource practices and procedural fairness all contributing factors to the quality of the shop steward-management relationship. The model tested for production employees investigated the relationship between the factors human resource practices, procedural fairness, the standardisation of work, the employees’ perception of the shop steward-management relationship and the relationship of the employees with both their supervisor and the organisation. The primary finding was that the perception that the production employees held regarding the shop steward-management relationship fully mediated the employees’ relationship with the organisation and partially mediated that with the supervisor. These findings confirm the mediating position occupied by shop stewards within unionised companies and without derogating the importance of supervisory-employee relationships, indicated the central importance of the management-shop steward relations in forging strong employee-manager and employee-organisational bonds. While the original purpose of the study included investigating the link between the key employment relationships, namely, shop steward-management, employee-supervisor and employee-organisation relationships, and company competitiveness, unfortunately due to the limited number of companies that participated, it was not possible to test a company level model that included company performance. However, tentative support was found for relationships between the shop steward-management relationship and company performance. This remains an area for further study.
- Full Text:
- Date Issued: 2019
- Authors: Bowler, Jennifer
- Date: 2019
- Subjects: Industrial relations, South Africa , Psychology, Industrial Work environment Industrial relations Labor unions
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10948/37150 , vital:34126
- Description: South Africa is consistently portrayed as having uncooperative union-management relationships which negatively impact competitiveness. However, the post-1994 labour legislation was specifically crafted with the intention of positioning the adversarial wealth distribution phase of the union-management relationship within centralised bargaining forums and promoting cooperative relationships within workplaces. The purpose of this study was to investigate whether within the South Africa context of global competitiveness, the employment relations institutions of centralised and decentralised collective bargaining, employee participation and involvement, in the context of organisational justice, have contributed to management, shop stewards and production employees developing effective1 collective and individual employment relationships positively associated with competitive individual and company performance. The targeted population were companies within the Nelson Mandela Metropolitan Area that were registered with one of the four bargaining councils, Automotive (NBF), Automotive component (MIBCO), New Tyre (NTMIBC) and Metal and Engineering (MEIBC). In addition, since the National Union of Metal Workers was the dominant union in all four of these councils, an additional criterion for potential participation was at least one NUMSA shop steward. Fourteen companies agreed to participate. In total 63 shop stewards, 82 managers and 660 production employees were surveyed using self-administered questionnaires. The results of the study identified that the three major stakeholders hold significantly different perceptions regarding the quality of the management-shop steward relationship, with management the most positive and production employees the least. Further, investigating the factors that influence the perceptions that management and shop stewards have of their relationship, it was identified that for management the most influential factor was their beliefs regarding the interdependent nature of the relationship. For the shop stewards the situation was more nuanced with beliefs regarding interdependence, the perceptions of shop steward-management climate within the bargaining council, satisfaction 1 Definition of an effective employment relationship: An effective employment relationship is one in which the parties successfully resolve issues arising from their conflicting interests and successfully pursue joint gains where they share common interests (Kochan & Katz, 1988) with bargaining council agreements and workplace human resource practices and procedural fairness all contributing factors to the quality of the shop steward-management relationship. The model tested for production employees investigated the relationship between the factors human resource practices, procedural fairness, the standardisation of work, the employees’ perception of the shop steward-management relationship and the relationship of the employees with both their supervisor and the organisation. The primary finding was that the perception that the production employees held regarding the shop steward-management relationship fully mediated the employees’ relationship with the organisation and partially mediated that with the supervisor. These findings confirm the mediating position occupied by shop stewards within unionised companies and without derogating the importance of supervisory-employee relationships, indicated the central importance of the management-shop steward relations in forging strong employee-manager and employee-organisational bonds. While the original purpose of the study included investigating the link between the key employment relationships, namely, shop steward-management, employee-supervisor and employee-organisation relationships, and company competitiveness, unfortunately due to the limited number of companies that participated, it was not possible to test a company level model that included company performance. However, tentative support was found for relationships between the shop steward-management relationship and company performance. This remains an area for further study.
- Full Text:
- Date Issued: 2019
Anthropological study on perceptions of gender inequality in soccer: the case of selected Tsakane township schools
- Bogopa, David Legodi, Kwatsha, Linda
- Authors: Bogopa, David Legodi , Kwatsha, Linda
- Date: 2019
- Subjects: Gender mainstreaming -- South Africa -- Gauteng , Sex discrimination Sex discrimination against women
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10948/45172 , vital:38260
- Description: This study sought to investigate the perception of gender inequality within sport policies in Gauteng province at the two schools, namely, Khombindlela Primary School and Reshogofaditswe Secondary School. The aim of this research was to determine the meaning of gender inequality from an anthropological perspective within the context of soccer in Gauteng Province at the two schools, namely, Khombindlela Primary School and Reshogofaditswe Secondary School and also to understand the issue of gender inequality in soccer in the post-apartheid period. The research objectives were as follows, firstly, to determine the impact of gender inequality in soccer at the two schools, namely, Khombindlela Primary School and Reshogofaditswe Secondary School. Secondly, the research sought to provide the recommendations for policy improvement within soccer in Gauteng Province and possibly at the nation level. Thirdly, the research also sought to add to the existing anthropological knowledge base on the impact of gender inequality on policy development relating to soccer. This research has followed the qualitative approach which includes, person to person interviews using an interview schedule. The researcher has also used observation as a research tool during the interviews. The data collection techniques employed in this study included interviews and observation (primary sources) and information gathered from relevant scholarly journals, books, newspapers, magazines, internet articles and sport policy documents (secondary sources). Ethics considerations were also covered from the proposal stage up to the final stage. The Marxist Feminist theoretical framework was used to understand issues of gender inequality in soccer particularly within the context of two Tsakane township schools, namely, Khombindlela Primary School and Reshogofaditswe Secondary School. Finally, a summary of each chapter was highlighted followed by the research findings and recommendations.
- Full Text:
- Date Issued: 2019
- Authors: Bogopa, David Legodi , Kwatsha, Linda
- Date: 2019
- Subjects: Gender mainstreaming -- South Africa -- Gauteng , Sex discrimination Sex discrimination against women
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10948/45172 , vital:38260
- Description: This study sought to investigate the perception of gender inequality within sport policies in Gauteng province at the two schools, namely, Khombindlela Primary School and Reshogofaditswe Secondary School. The aim of this research was to determine the meaning of gender inequality from an anthropological perspective within the context of soccer in Gauteng Province at the two schools, namely, Khombindlela Primary School and Reshogofaditswe Secondary School and also to understand the issue of gender inequality in soccer in the post-apartheid period. The research objectives were as follows, firstly, to determine the impact of gender inequality in soccer at the two schools, namely, Khombindlela Primary School and Reshogofaditswe Secondary School. Secondly, the research sought to provide the recommendations for policy improvement within soccer in Gauteng Province and possibly at the nation level. Thirdly, the research also sought to add to the existing anthropological knowledge base on the impact of gender inequality on policy development relating to soccer. This research has followed the qualitative approach which includes, person to person interviews using an interview schedule. The researcher has also used observation as a research tool during the interviews. The data collection techniques employed in this study included interviews and observation (primary sources) and information gathered from relevant scholarly journals, books, newspapers, magazines, internet articles and sport policy documents (secondary sources). Ethics considerations were also covered from the proposal stage up to the final stage. The Marxist Feminist theoretical framework was used to understand issues of gender inequality in soccer particularly within the context of two Tsakane township schools, namely, Khombindlela Primary School and Reshogofaditswe Secondary School. Finally, a summary of each chapter was highlighted followed by the research findings and recommendations.
- Full Text:
- Date Issued: 2019
Anti-HIV-1 integrase potency of methylgallate from Alchornea cordifolia using in vitro and in silico approaches:
- Noundou, Xavier S, Musyoka, Thommas M, Moses, Vuyani, Ndinteh, Derek T, Mnkandhla, Dumisani, Hoppe, Heinrich C, Tastan Bishop, Özlem, Krause, Rui W M
- Authors: Noundou, Xavier S , Musyoka, Thommas M , Moses, Vuyani , Ndinteh, Derek T , Mnkandhla, Dumisani , Hoppe, Heinrich C , Tastan Bishop, Özlem , Krause, Rui W M
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/162975 , vital:41001 , https://0-doi.org.wam.seals.ac.za/10.1038/s41598-019-41403-x
- Description: According to the 2018 report of the United Nations Programme on HIV/AIDS (UNAIDS), acquired immune deficiency syndrome (AIDS), a disease caused by the human immunodeficiency virus (HIV), remains a significant public health problem. The non-existence of a cure or effective vaccine for the disease and the associated emergence of resistant viral strains imply an urgent need for the discovery of novel anti-HIV drug candidates. The current study aimed to identify potential anti-retroviral compounds from Alchornea cordifolia.
- Full Text:
- Date Issued: 2019
- Authors: Noundou, Xavier S , Musyoka, Thommas M , Moses, Vuyani , Ndinteh, Derek T , Mnkandhla, Dumisani , Hoppe, Heinrich C , Tastan Bishop, Özlem , Krause, Rui W M
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/162975 , vital:41001 , https://0-doi.org.wam.seals.ac.za/10.1038/s41598-019-41403-x
- Description: According to the 2018 report of the United Nations Programme on HIV/AIDS (UNAIDS), acquired immune deficiency syndrome (AIDS), a disease caused by the human immunodeficiency virus (HIV), remains a significant public health problem. The non-existence of a cure or effective vaccine for the disease and the associated emergence of resistant viral strains imply an urgent need for the discovery of novel anti-HIV drug candidates. The current study aimed to identify potential anti-retroviral compounds from Alchornea cordifolia.
- Full Text:
- Date Issued: 2019
Anticancer evaluation of ruthenium (III) complexes with N-donor ligands tethered to coumarin or uracil moieties:
- Gramni, Larusha, Vukea, Nyeleti, Chakraborty, Abir, Samson, William J, Dingle, Laura M K, Xulu, Bheki, de la Mare, Jo-Anne, Edkins, Adrienne L, Booysen, Irvin N
- Authors: Gramni, Larusha , Vukea, Nyeleti , Chakraborty, Abir , Samson, William J , Dingle, Laura M K , Xulu, Bheki , de la Mare, Jo-Anne , Edkins, Adrienne L , Booysen, Irvin N
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/163477 , vital:41041 , DOI: 10.1016/j.ica.2019.04.01
- Description: In this study, the synthesis and characterization of new paramagnetic ruthenium(III) complexes: cis-[RuCl2(urdpa)] (1) {Hurdpa = 6-((bis(pyridin-2-ylmethyl)amino)methyl)uracil} and fac-[RuCl3(chrdpa)] (2) {chrdpa = 4-((bis(pyridin-2-ylmethyl)amino)methyl)-7-methoxycoumarin} are reported. These metal complexes have been comprehensively characterized by an array of physicochemical techniques and the X-ray solid-state structures of 1 and Hurdpa have been attained.
- Full Text:
- Date Issued: 2019
- Authors: Gramni, Larusha , Vukea, Nyeleti , Chakraborty, Abir , Samson, William J , Dingle, Laura M K , Xulu, Bheki , de la Mare, Jo-Anne , Edkins, Adrienne L , Booysen, Irvin N
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/163477 , vital:41041 , DOI: 10.1016/j.ica.2019.04.01
- Description: In this study, the synthesis and characterization of new paramagnetic ruthenium(III) complexes: cis-[RuCl2(urdpa)] (1) {Hurdpa = 6-((bis(pyridin-2-ylmethyl)amino)methyl)uracil} and fac-[RuCl3(chrdpa)] (2) {chrdpa = 4-((bis(pyridin-2-ylmethyl)amino)methyl)-7-methoxycoumarin} are reported. These metal complexes have been comprehensively characterized by an array of physicochemical techniques and the X-ray solid-state structures of 1 and Hurdpa have been attained.
- Full Text:
- Date Issued: 2019
Anticholinesterase and Antioxidant Activities of Spilanthes filicaulis Whole Plant Extracts for the Management of Alzheimer’s Disease
- Elufioye, Taiwo O., Unachukwu, Cynthia C., Oyedeji, Adebola O.
- Authors: Elufioye, Taiwo O. , Unachukwu, Cynthia C. , Oyedeji, Adebola O.
- Date: 2019
- Subjects: Alzheimer’s disease , Cholinesterase inhibitors , Antioxidants , Spilanthes , Flavonoids , Phenolic
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/6534 , vital:46450 , xlink:href="https://10.2174/1573408015666190730113405"
- Description: Background: Spilanthes filicaulis is a tropical herb implicated as a memory enhancer in ethnomedicine. Objective: The study investigated acetyl/butyryl cholinesterase inhibitory and antioxidant activities of different extracts of S. filicaulis whole plant and correlated them to its phytochemical constituents. Methods: The powdered whole plant was successively extracted with n-hexane, ethyl acetate and methanol. Acetyl cholinesterase (AChE) and Butyryl cholinesterase (BuChE) inhibitory activity were evaluated by Ellman colorimetry assay. Antioxidant activity was tested using 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, ferric reducing power and nitric oxide scavenging assays. Total phenolic, flavonoid and tannin were estimated using standard methods. Correlation was determined using Quest Graph™ Regression Calculator. Results: Various extracts exhibited concentration-dependent AChE and BuChE inhibitory activity with ethyl acetate extract being the highest with IC50 of 0.77 μg/mL and 0.92 μg/mL for AChE and BuChE respectively. The ethyl acetate extract also showed the highest reducing power when compared with the other extracts. The methanol extract had slightly higher phenolic and flavonoid content and showed the highest DPPH radical scavenging effect. DPPH scavenging, AChE and BuChE inhibition had high correlation with the total flavonoid content with R2 values of 1.00, 0.800 and 0.992 respectively while nitric oxide scavenging had high correlation with phenolics and tannins with R2 = 0.942 and 0.806 respectively. Conclusion: These results show that the extracts of the whole plant of S. filicaulis possess significant AChE/BuChE inhibitory and antioxidant properties, mostly due to its flavonoid content, suggesting the possible use of the plant in neurodegenerative diseases such as AD.
- Full Text:
- Date Issued: 2019
- Authors: Elufioye, Taiwo O. , Unachukwu, Cynthia C. , Oyedeji, Adebola O.
- Date: 2019
- Subjects: Alzheimer’s disease , Cholinesterase inhibitors , Antioxidants , Spilanthes , Flavonoids , Phenolic
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/6534 , vital:46450 , xlink:href="https://10.2174/1573408015666190730113405"
- Description: Background: Spilanthes filicaulis is a tropical herb implicated as a memory enhancer in ethnomedicine. Objective: The study investigated acetyl/butyryl cholinesterase inhibitory and antioxidant activities of different extracts of S. filicaulis whole plant and correlated them to its phytochemical constituents. Methods: The powdered whole plant was successively extracted with n-hexane, ethyl acetate and methanol. Acetyl cholinesterase (AChE) and Butyryl cholinesterase (BuChE) inhibitory activity were evaluated by Ellman colorimetry assay. Antioxidant activity was tested using 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, ferric reducing power and nitric oxide scavenging assays. Total phenolic, flavonoid and tannin were estimated using standard methods. Correlation was determined using Quest Graph™ Regression Calculator. Results: Various extracts exhibited concentration-dependent AChE and BuChE inhibitory activity with ethyl acetate extract being the highest with IC50 of 0.77 μg/mL and 0.92 μg/mL for AChE and BuChE respectively. The ethyl acetate extract also showed the highest reducing power when compared with the other extracts. The methanol extract had slightly higher phenolic and flavonoid content and showed the highest DPPH radical scavenging effect. DPPH scavenging, AChE and BuChE inhibition had high correlation with the total flavonoid content with R2 values of 1.00, 0.800 and 0.992 respectively while nitric oxide scavenging had high correlation with phenolics and tannins with R2 = 0.942 and 0.806 respectively. Conclusion: These results show that the extracts of the whole plant of S. filicaulis possess significant AChE/BuChE inhibitory and antioxidant properties, mostly due to its flavonoid content, suggesting the possible use of the plant in neurodegenerative diseases such as AD.
- Full Text:
- Date Issued: 2019
Antihypertensive effects of the hydroethanol extract of Senecio serratuloides DC in rats
- Tata, Charlotte Mungho, Sewani-Rusike, Constance Rufaro, Oyedeji, Opeoluwa Oyehan, Gwebu, Ephraim Tobela, Mahlakata, Fikile, Nkeh-Chungag, Benedicta Ngwenchi
- Authors: Tata, Charlotte Mungho , Sewani-Rusike, Constance Rufaro , Oyedeji, Opeoluwa Oyehan , Gwebu, Ephraim Tobela , Mahlakata, Fikile , Nkeh-Chungag, Benedicta Ngwenchi
- Date: 2019
- Subjects: South Africa Hypertension Computer File
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/5847 , vital:44656 , https://doi.org/10.1186/s12906-019-2463-2
- Description: Senecio serratuloides DC is used in folk medicine for treating hypertension, skin disorders, internal and external sores, rashes, burns and wounds. This study aimed at investigating the antihypertensive effects of the hydroethanol extract of S. serratuloides (HESS) in N-Nitro-L-arginine methyl ester (L-NAME) induced hypertension in rats. Methods: Acute toxicity of HESS was first determined to provide guidance on doses to be used in this study. Lorke’s method was used to determine safety of the extract in mice. Female Wistar rats were treated orally once daily with L-NAME (40 mg/kg) for 4 weeks and then concomitantly with L-NAME (20 mg/kg) and plant extract (150 and 300 mg/kg), captopril (20 mg/kg) or saline as per assigned group for 2 weeks followed by a 2-week period of assigned treatments only. Blood pressure was monitored weekly. Lipid profile, nitric oxide, renin and angiotensin II concentrations were determined in serum while mineralocorticoid receptor concentration was quantified in the kidney homogenate. Nitric oxide (NO) concentration was determined in serum and cardiac histology performed. Results HESS was found to be non-toxic, having a LD50 greater than 5000 mg/kg. Blood pressure increased progressively in all animals from the second week of L-NAME treatment. HESS treatment significantly and dose-dependently lowered systolic blood pressure (p less 0.001), diastolic blood pressure (p less 0.01), low density lipoprotein cholesterol (p less 0.01) and triglycerides (p less 0.01). It significantly prevented L-NAME induced decrease in serum angiotensin II (p less 0.01), high density lipoprotein cholesterol (p less 0.001) and serum nitric oxide concentrations (p less 0.001). HESS also significantly (p less 0.01) prevented collagen deposition in cardiac tissue. Conclusion The hydro-ethanol extract of Senecio serratuloides showed antihypertensive, antihyperlipidemic and cardioprotective effects in rats thus confirming its usefulness in traditional antihypertensive therapy and potential for antihypertensive drug development.
- Full Text:
- Date Issued: 2019
- Authors: Tata, Charlotte Mungho , Sewani-Rusike, Constance Rufaro , Oyedeji, Opeoluwa Oyehan , Gwebu, Ephraim Tobela , Mahlakata, Fikile , Nkeh-Chungag, Benedicta Ngwenchi
- Date: 2019
- Subjects: South Africa Hypertension Computer File
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/5847 , vital:44656 , https://doi.org/10.1186/s12906-019-2463-2
- Description: Senecio serratuloides DC is used in folk medicine for treating hypertension, skin disorders, internal and external sores, rashes, burns and wounds. This study aimed at investigating the antihypertensive effects of the hydroethanol extract of S. serratuloides (HESS) in N-Nitro-L-arginine methyl ester (L-NAME) induced hypertension in rats. Methods: Acute toxicity of HESS was first determined to provide guidance on doses to be used in this study. Lorke’s method was used to determine safety of the extract in mice. Female Wistar rats were treated orally once daily with L-NAME (40 mg/kg) for 4 weeks and then concomitantly with L-NAME (20 mg/kg) and plant extract (150 and 300 mg/kg), captopril (20 mg/kg) or saline as per assigned group for 2 weeks followed by a 2-week period of assigned treatments only. Blood pressure was monitored weekly. Lipid profile, nitric oxide, renin and angiotensin II concentrations were determined in serum while mineralocorticoid receptor concentration was quantified in the kidney homogenate. Nitric oxide (NO) concentration was determined in serum and cardiac histology performed. Results HESS was found to be non-toxic, having a LD50 greater than 5000 mg/kg. Blood pressure increased progressively in all animals from the second week of L-NAME treatment. HESS treatment significantly and dose-dependently lowered systolic blood pressure (p less 0.001), diastolic blood pressure (p less 0.01), low density lipoprotein cholesterol (p less 0.01) and triglycerides (p less 0.01). It significantly prevented L-NAME induced decrease in serum angiotensin II (p less 0.01), high density lipoprotein cholesterol (p less 0.001) and serum nitric oxide concentrations (p less 0.001). HESS also significantly (p less 0.01) prevented collagen deposition in cardiac tissue. Conclusion The hydro-ethanol extract of Senecio serratuloides showed antihypertensive, antihyperlipidemic and cardioprotective effects in rats thus confirming its usefulness in traditional antihypertensive therapy and potential for antihypertensive drug development.
- Full Text:
- Date Issued: 2019
Antihypertensive effects of the hydroethanol extract of Senecio serratuloides DC in rats
- Tata, Charlotte Mungho, Sewani-Rusike, Constance Rufaro, Oyedeji, Opeoluwa Oyehan, Gwebu, Ephraim Tobela, Mahlakata, Fikile, Nkeh-Chungag, Benedicta Ngwenchi
- Authors: Tata, Charlotte Mungho , Sewani-Rusike, Constance Rufaro , Oyedeji, Opeoluwa Oyehan , Gwebu, Ephraim Tobela , Mahlakata, Fikile , Nkeh-Chungag, Benedicta Ngwenchi
- Date: 2019
- Subjects: South Africa Hypertension Computer File
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/5842 , vital:44654 , https://doi.org/10.1186/s12906-019-2463-2
- Description: Senecio serratuloides DC is used in folk medicine for treating hypertension, skin disorders, internal and external sores, rashes, burns and wounds. This study aimed at investigating the antihypertensive effects of the hydroethanol extract of S. serratuloides (HESS) in N-Nitro-L-arginine methyl ester (L-NAME) induced hypertension in rats. Methods: Acute toxicity of HESS was first determined to provide guidance on doses to be used in this study. Lorke’s method was used to determine safety of the extract in mice. Female Wistar rats were treated orally once daily with L-NAME (40 mg/kg) for 4 weeks and then concomitantly with L-NAME (20 mg/kg) and plant extract (150 and 300 mg/kg), captopril (20 mg/kg) or saline as per assigned group for 2 weeks followed by a 2-week period of assigned treatments only. Blood pressure was monitored weekly. Lipid profile, nitric oxide, renin and angiotensin II concentrations were determined in serum while mineralocorticoid receptor concentration was quantified in the kidney homogenate. Nitric oxide (NO) concentration was determined in serum and cardiac histology performed. Results HESS was found to be non-toxic, having a LD50 greater than 5000 mg/kg. Blood pressure increased progressively in all animals from the second week of L-NAME treatment. HESS treatment significantly and dose-dependently lowered systolic blood pressure (p less 0.001), diastolic blood pressure (p less 0.01), low density lipoprotein cholesterol (p less 0.01) and triglycerides (p less 0.01). It significantly prevented L-NAME induced decrease in serum angiotensin II (p less 0.01), high density lipoprotein cholesterol (p less 0.001) and serum nitric oxide concentrations (p less 0.001). HESS also significantly (p less 0.01) prevented collagen deposition in cardiac tissue. Conclusion The hydro-ethanol extract of Senecio serratuloides showed antihypertensive, antihyperlipidemic and cardioprotective effects in rats thus confirming its usefulness in traditional antihypertensive therapy and potential for antihypertensive drug development.
- Full Text:
- Date Issued: 2019
- Authors: Tata, Charlotte Mungho , Sewani-Rusike, Constance Rufaro , Oyedeji, Opeoluwa Oyehan , Gwebu, Ephraim Tobela , Mahlakata, Fikile , Nkeh-Chungag, Benedicta Ngwenchi
- Date: 2019
- Subjects: South Africa Hypertension Computer File
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/5842 , vital:44654 , https://doi.org/10.1186/s12906-019-2463-2
- Description: Senecio serratuloides DC is used in folk medicine for treating hypertension, skin disorders, internal and external sores, rashes, burns and wounds. This study aimed at investigating the antihypertensive effects of the hydroethanol extract of S. serratuloides (HESS) in N-Nitro-L-arginine methyl ester (L-NAME) induced hypertension in rats. Methods: Acute toxicity of HESS was first determined to provide guidance on doses to be used in this study. Lorke’s method was used to determine safety of the extract in mice. Female Wistar rats were treated orally once daily with L-NAME (40 mg/kg) for 4 weeks and then concomitantly with L-NAME (20 mg/kg) and plant extract (150 and 300 mg/kg), captopril (20 mg/kg) or saline as per assigned group for 2 weeks followed by a 2-week period of assigned treatments only. Blood pressure was monitored weekly. Lipid profile, nitric oxide, renin and angiotensin II concentrations were determined in serum while mineralocorticoid receptor concentration was quantified in the kidney homogenate. Nitric oxide (NO) concentration was determined in serum and cardiac histology performed. Results HESS was found to be non-toxic, having a LD50 greater than 5000 mg/kg. Blood pressure increased progressively in all animals from the second week of L-NAME treatment. HESS treatment significantly and dose-dependently lowered systolic blood pressure (p less 0.001), diastolic blood pressure (p less 0.01), low density lipoprotein cholesterol (p less 0.01) and triglycerides (p less 0.01). It significantly prevented L-NAME induced decrease in serum angiotensin II (p less 0.01), high density lipoprotein cholesterol (p less 0.001) and serum nitric oxide concentrations (p less 0.001). HESS also significantly (p less 0.01) prevented collagen deposition in cardiac tissue. Conclusion The hydro-ethanol extract of Senecio serratuloides showed antihypertensive, antihyperlipidemic and cardioprotective effects in rats thus confirming its usefulness in traditional antihypertensive therapy and potential for antihypertensive drug development.
- Full Text:
- Date Issued: 2019
Antimicrobial resistance awareness program at Settlers Hospital
- Manhanzva, Rufaro Immaculate
- Authors: Manhanzva, Rufaro Immaculate
- Date: 2019
- Language: English
- Type: text , Thesis , Masters , MPharm
- Identifier: http://hdl.handle.net/10962/97712 , vital:31475
- Description: Expected release date-April 2021
- Full Text: false
- Date Issued: 2019
- Authors: Manhanzva, Rufaro Immaculate
- Date: 2019
- Language: English
- Type: text , Thesis , Masters , MPharm
- Identifier: http://hdl.handle.net/10962/97712 , vital:31475
- Description: Expected release date-April 2021
- Full Text: false
- Date Issued: 2019
Antiplasmodial Activity of the n-Hexane Extract from Pleurotus ostreatus (Jacq. ex. Fr) P. Kumm
- Afieroho, Ozadheoghene E, Siwe-Noundou, Xavier, Onyia, Chiazor P, Festus, Osamuyi H, Chukwu, Elizabeth C, Adedokun, Olutayo M, Isaacs, Michelle, Hoppe, Heinrich C, Krause, Rui W M, Abo, Kio A
- Authors: Afieroho, Ozadheoghene E , Siwe-Noundou, Xavier , Onyia, Chiazor P , Festus, Osamuyi H , Chukwu, Elizabeth C , Adedokun, Olutayo M , Isaacs, Michelle , Hoppe, Heinrich C , Krause, Rui W M , Abo, Kio A
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/194981 , vital:45516 , xlink:href="https://doi.org/10.4274/tjps.18894"
- Description: Objectives: Several mushrooms species have been reported to be nematophagous and antiprotozoan. This study reported the antiplasmodial and cytotoxic properties of the n-hexane extract from the edible mushroom Pleurotus ostreatus and the isolation of a sterol from the extract. Materials and Methods: Antiplasmodial and cytotoxicity assays were done in vitro using the plasmodium lactate dehydrogenase assay and human HeLa cervical cell lines, respectively. The structure of the isolated compound from the n-hexane extract was elucidated using spectroscopic techniques. Results: The n-hexane extract (yield: 0.93% w/w) showed dose dependent antiplasmodial activity with the trend in parasite inhibition of: chloroquine (IC50=0.016 μg/mL) > n-hexane extract (IC50=25.18 μg/mL). It also showed mild cytotoxicity (IC50>100 μg/mL; selectivity index >4) compared to the reference drug emetine (IC50=0.013 μg/mL). The known sterol, ergostan-5,7,22-trien-3-ol, was isolated and characterized from the extract. Conclusion: This study reporting for the first time the antiplasmodial activity of P. ostreatus revealed its nutraceutical potential in the management of malaria.
- Full Text:
- Date Issued: 2019
- Authors: Afieroho, Ozadheoghene E , Siwe-Noundou, Xavier , Onyia, Chiazor P , Festus, Osamuyi H , Chukwu, Elizabeth C , Adedokun, Olutayo M , Isaacs, Michelle , Hoppe, Heinrich C , Krause, Rui W M , Abo, Kio A
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/194981 , vital:45516 , xlink:href="https://doi.org/10.4274/tjps.18894"
- Description: Objectives: Several mushrooms species have been reported to be nematophagous and antiprotozoan. This study reported the antiplasmodial and cytotoxic properties of the n-hexane extract from the edible mushroom Pleurotus ostreatus and the isolation of a sterol from the extract. Materials and Methods: Antiplasmodial and cytotoxicity assays were done in vitro using the plasmodium lactate dehydrogenase assay and human HeLa cervical cell lines, respectively. The structure of the isolated compound from the n-hexane extract was elucidated using spectroscopic techniques. Results: The n-hexane extract (yield: 0.93% w/w) showed dose dependent antiplasmodial activity with the trend in parasite inhibition of: chloroquine (IC50=0.016 μg/mL) > n-hexane extract (IC50=25.18 μg/mL). It also showed mild cytotoxicity (IC50>100 μg/mL; selectivity index >4) compared to the reference drug emetine (IC50=0.013 μg/mL). The known sterol, ergostan-5,7,22-trien-3-ol, was isolated and characterized from the extract. Conclusion: This study reporting for the first time the antiplasmodial activity of P. ostreatus revealed its nutraceutical potential in the management of malaria.
- Full Text:
- Date Issued: 2019
Application of computational methods in elucidating the isomerization step in the biosynthesis of coumarins
- Authors: Tshiwawa, Tendamudzimu
- Date: 2019
- Subjects: Coumarins , Isomerization , Biosynthesis , Organic compounds -- Synthesis , Cinnamic acid
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/67646 , vital:29124
- Description: The identity of the enzyme(s) responsible for the biosynthetic transformation of cinnamic acid derivatives to important, naturally occurring coumarins has yet to be established. This study constitutes a high-level theoretical analysis of the possibility that a recently reported molecular mechanism of the synthesis of coumarins from Baylis-Hillman adducts, may provide a viable model for three critical phases in the biosynthetic pathway Particular attention has been given to the first of these phases: i) E→Z isomerisation of the cinnamic acid precursor; ii) Cyclisation (lactonisation) to the hemi-acetal intermediate; and ii) Dehydration to afford the coumarin derivative. In order to accomplish this analysis, an enzyme capable, theoretically, of effecting this E→Z isomerisation required identification, and its potential involvement in the transformation mechanism explored. Combined Molecular Mechanics and high-level Quantum Mechanical/DFT calculations were used to access complementary models of appropriate complexes and relevant processes within the enzyme active sites of a range of eleven Chalcone Isomerase (CHI) enzyme candidates, the structures of which were downloaded from the Protein Data Bank. Detailed B3LYP/6-31+G(d,p) calculations have provided pictures of the relative populations of conformations within the ensemble of conformations available at normal temperatures. Conformations of several protonation states of cinnamic acid derivatives have been studied in this way, and the results obtained showed that coupled protonation and deprotonation of (E)-o-coumaric acid provides a viable approach to achieve the E→Z isomerization. In silico docking of the B3LYP/6-31+G(d,p) optimized (E)-o-coumaric acid derivatives in the active sites of each of the candidate CHI enzymes (CHI) revealed that (E)-o-coumaric acid fits well within the active sites of Medicago Sativa CHI crystallographic structures with 1FM8 showing best potential for not only accommodating (E)-o-coumaric acid , but also providing appropriate protein active site residues to effect the simultaneous protonation and deprotonation of the substrate , two residues being optimally placed to facilitate these critical processes. Further exploration of the chemical properties and qualities of selected CHI enzymes, undertaken using High Throughput Virtual Screening (HTVS), confirmed 1FM8 as a viable choice for further studies of the enzyme-catalysed E→Z isomerization of (E)-o-coumaric acid. A molecular dynamics study, performed to further evaluate the evolution of (E)-o-coumaric acid in the CHI active site over time, showed that the ligand in the 1FM8 active site is not only stable, but also that the desired protein-ligand interactions persist throughout the simulation period to facilitate the E→Z isomerization. An integrated molecular orbital and molecular mechanics (ONIOM) study of the 1FM8-(E)-o-coumaric acid complex, involving the direct protonation and deprotonation of the ligand by protein residues; has provided a plausible mechanism for the E → Z isomerization of (E)-o-coumaric acid within the 1FM8 active site; a transition state complex (with an activation energy of ca. 50 kCal.mol-1) has been located and its connection with both the (E)- and (Z)-o-coumaric acid isomer has been confirmed by Intrinsic Reaction Coordinate (IRC) calculations. More realistic models of the 1FM8-(E)-o-coumaric acid complex, with the inclusion of water solvent molecules, have been obtained at both the QM/MM and adaptive QM/MM levels which simulate the dynamic active site at the QM level. The results indicate that the simultaneous protonation and deprotonation of (E)-o-coumaric acid within the CHI enzyme is a water-mediated process – a conclusion consistent with similar reported processes. Visual inspection of the 1FM8-(Z)-o-coumaric acid complex reveals both the necessary orientation of the phenolic and carboxylic acid moieties of the (Z)-o-coumaric acid and the presence of appropriate, proximal active site residues with the potential to permit catalysis of the subsequent lactonisation and dehydration steps required to generate coumarin.
- Full Text:
- Date Issued: 2019
- Authors: Tshiwawa, Tendamudzimu
- Date: 2019
- Subjects: Coumarins , Isomerization , Biosynthesis , Organic compounds -- Synthesis , Cinnamic acid
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/67646 , vital:29124
- Description: The identity of the enzyme(s) responsible for the biosynthetic transformation of cinnamic acid derivatives to important, naturally occurring coumarins has yet to be established. This study constitutes a high-level theoretical analysis of the possibility that a recently reported molecular mechanism of the synthesis of coumarins from Baylis-Hillman adducts, may provide a viable model for three critical phases in the biosynthetic pathway Particular attention has been given to the first of these phases: i) E→Z isomerisation of the cinnamic acid precursor; ii) Cyclisation (lactonisation) to the hemi-acetal intermediate; and ii) Dehydration to afford the coumarin derivative. In order to accomplish this analysis, an enzyme capable, theoretically, of effecting this E→Z isomerisation required identification, and its potential involvement in the transformation mechanism explored. Combined Molecular Mechanics and high-level Quantum Mechanical/DFT calculations were used to access complementary models of appropriate complexes and relevant processes within the enzyme active sites of a range of eleven Chalcone Isomerase (CHI) enzyme candidates, the structures of which were downloaded from the Protein Data Bank. Detailed B3LYP/6-31+G(d,p) calculations have provided pictures of the relative populations of conformations within the ensemble of conformations available at normal temperatures. Conformations of several protonation states of cinnamic acid derivatives have been studied in this way, and the results obtained showed that coupled protonation and deprotonation of (E)-o-coumaric acid provides a viable approach to achieve the E→Z isomerization. In silico docking of the B3LYP/6-31+G(d,p) optimized (E)-o-coumaric acid derivatives in the active sites of each of the candidate CHI enzymes (CHI) revealed that (E)-o-coumaric acid fits well within the active sites of Medicago Sativa CHI crystallographic structures with 1FM8 showing best potential for not only accommodating (E)-o-coumaric acid , but also providing appropriate protein active site residues to effect the simultaneous protonation and deprotonation of the substrate , two residues being optimally placed to facilitate these critical processes. Further exploration of the chemical properties and qualities of selected CHI enzymes, undertaken using High Throughput Virtual Screening (HTVS), confirmed 1FM8 as a viable choice for further studies of the enzyme-catalysed E→Z isomerization of (E)-o-coumaric acid. A molecular dynamics study, performed to further evaluate the evolution of (E)-o-coumaric acid in the CHI active site over time, showed that the ligand in the 1FM8 active site is not only stable, but also that the desired protein-ligand interactions persist throughout the simulation period to facilitate the E→Z isomerization. An integrated molecular orbital and molecular mechanics (ONIOM) study of the 1FM8-(E)-o-coumaric acid complex, involving the direct protonation and deprotonation of the ligand by protein residues; has provided a plausible mechanism for the E → Z isomerization of (E)-o-coumaric acid within the 1FM8 active site; a transition state complex (with an activation energy of ca. 50 kCal.mol-1) has been located and its connection with both the (E)- and (Z)-o-coumaric acid isomer has been confirmed by Intrinsic Reaction Coordinate (IRC) calculations. More realistic models of the 1FM8-(E)-o-coumaric acid complex, with the inclusion of water solvent molecules, have been obtained at both the QM/MM and adaptive QM/MM levels which simulate the dynamic active site at the QM level. The results indicate that the simultaneous protonation and deprotonation of (E)-o-coumaric acid within the CHI enzyme is a water-mediated process – a conclusion consistent with similar reported processes. Visual inspection of the 1FM8-(Z)-o-coumaric acid complex reveals both the necessary orientation of the phenolic and carboxylic acid moieties of the (Z)-o-coumaric acid and the presence of appropriate, proximal active site residues with the potential to permit catalysis of the subsequent lactonisation and dehydration steps required to generate coumarin.
- Full Text:
- Date Issued: 2019
Application of some missing data techniques in estimating missing data in high blood pressure covariates
- Authors: Odeyemi, A. S
- Date: 2019
- Subjects: Missing observations (Statistics) Hypertension
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/15189 , vital:40195
- Description: Cases recorded with high blood pressure are a major concern in both public and private hospitals. Adequate provision of health information of patients relating to high blood pressure in Eastern Cape Hospitals hinges so much on the outcome of statistical analysis results. The usual statistical methodologies become inadequate in handling statistical analysis of data collected due to incomplete patients’ information stored in the hospital database. From time to time, new methods are developed to address the problem of missing data. High blood pressure is linked to a lot of diseases such hypertension, cardiovascular disease, kidney disease and stroke. In this study, we developed a new method for addressing the problem of missing data in assessing model used for estimating missing values in terms of minimum errors(using RMSE, MAE, and SE) and goodness-of-fits(using 2 R and adjusted 2 R ) of this model and P-value. . The study compared six different methods: Original data (OD), Listwise deletion (LD), Mean imputations (MEI), Mean above (MA), and Mean above below(MAB) and two steps nearest neighbour (2-NN).The comparison was performed using original data set, and missing values at 5%, 10%, 20%, 30% were simulated on Framingham risk scores under MCAR and MAR simulation on BMI values given some assumptions. Five performance indicators were used to describe the model minimum errors and goodness of fit for all the methods. The results showed that the 2-NN is the best replacement method at lower levels (5% and10%) of missing values while MA and MEI performed best at higher levels(15% and 20%) of missing values. All comparison was based on estimates closest to those of the original data where no value was missing. MAR results showed that 2-NN performed better than LD,MA,MAB, and MEI at 5%,10%, and 20% levels of missing data in terms of absolute difference in p-value to original data.
- Full Text:
- Date Issued: 2019
- Authors: Odeyemi, A. S
- Date: 2019
- Subjects: Missing observations (Statistics) Hypertension
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/15189 , vital:40195
- Description: Cases recorded with high blood pressure are a major concern in both public and private hospitals. Adequate provision of health information of patients relating to high blood pressure in Eastern Cape Hospitals hinges so much on the outcome of statistical analysis results. The usual statistical methodologies become inadequate in handling statistical analysis of data collected due to incomplete patients’ information stored in the hospital database. From time to time, new methods are developed to address the problem of missing data. High blood pressure is linked to a lot of diseases such hypertension, cardiovascular disease, kidney disease and stroke. In this study, we developed a new method for addressing the problem of missing data in assessing model used for estimating missing values in terms of minimum errors(using RMSE, MAE, and SE) and goodness-of-fits(using 2 R and adjusted 2 R ) of this model and P-value. . The study compared six different methods: Original data (OD), Listwise deletion (LD), Mean imputations (MEI), Mean above (MA), and Mean above below(MAB) and two steps nearest neighbour (2-NN).The comparison was performed using original data set, and missing values at 5%, 10%, 20%, 30% were simulated on Framingham risk scores under MCAR and MAR simulation on BMI values given some assumptions. Five performance indicators were used to describe the model minimum errors and goodness of fit for all the methods. The results showed that the 2-NN is the best replacement method at lower levels (5% and10%) of missing values while MA and MEI performed best at higher levels(15% and 20%) of missing values. All comparison was based on estimates closest to those of the original data where no value was missing. MAR results showed that 2-NN performed better than LD,MA,MAB, and MEI at 5%,10%, and 20% levels of missing data in terms of absolute difference in p-value to original data.
- Full Text:
- Date Issued: 2019
Applications of complex functions on problems in Banach algebras
- Authors: Snyman, Jandré Dillon
- Date: 2019
- Subjects: Banach algebras , Functions of several complex variables
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10948/48643 , vital:41055
- Description: In this dissertation, we provide applications of complex function theory to problems in Banach algebras. We discuss the structure of analytic functions f : D → A, where D is a domain of C and A is a Banach algebra as given by Aupetit in [3]: either the set {λ ∈ D : Sp(f(λ)) is finite} is of capacity zero, or there exists an integer n such that Sp(f(λ)) has exactly n elements, for every λ, except on a closed, discrete set of capacity zero, where the spectrum has at most n−1 elements. This deep result, which describes the structure of Sp(f(λ)) for all λ ∈ D, relies heavily on subharmonic techniques, which are also included in the dissertation. Let A and B be Banach algebras. A linear mapping φ : A → B is called a Jordan homomorphism if and only if φ(xy + yx) = φ(x)φ(y) + φ(y)φ(x) for every x, y ∈ A. This is equivalent to saying that φ(x 2 ) = φ(x) 2 for every x ∈ A. The following problem, due to I. Kaplansky, is still unsolved for the general Banach algebra case: Let A and B be unital Banach algebras and φ : A → B a unital, invertibility preserving linear mapping. Under what conditions of A and B is φ a Jordan homomorphism? The author’s honours project [24] served as an exposition of the GleasonKahane-Żelazko Theorem [7, Theorem 4], which provides an answer to Kaplansky’s problem in the case where B = C. In this dissertation we look at other special cases of Kaplansky’s problem, such as the case where A and B are von Neumann algberas, as solved by Aupetit [4, Theorem 1.3] and remark that his result holds for the more general case where A is any C ∗ -algebra that has the property that every self-adjoint element is the limit of a sequence of linear combinations of orthogonal idempotents in A, and B is a semi-simple Banach algebra. This result relies heavily on complex function theory, spectral theory and holomorphic functional calculus. We also provide detailed expositions of the work of Taylor [27] in which an operator calculus on undounded, closed linear operators is developed, and the work of Allan [1] in which a holomorphic functional calculus is defined for locally convex algebras.
- Full Text:
- Date Issued: 2019
- Authors: Snyman, Jandré Dillon
- Date: 2019
- Subjects: Banach algebras , Functions of several complex variables
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10948/48643 , vital:41055
- Description: In this dissertation, we provide applications of complex function theory to problems in Banach algebras. We discuss the structure of analytic functions f : D → A, where D is a domain of C and A is a Banach algebra as given by Aupetit in [3]: either the set {λ ∈ D : Sp(f(λ)) is finite} is of capacity zero, or there exists an integer n such that Sp(f(λ)) has exactly n elements, for every λ, except on a closed, discrete set of capacity zero, where the spectrum has at most n−1 elements. This deep result, which describes the structure of Sp(f(λ)) for all λ ∈ D, relies heavily on subharmonic techniques, which are also included in the dissertation. Let A and B be Banach algebras. A linear mapping φ : A → B is called a Jordan homomorphism if and only if φ(xy + yx) = φ(x)φ(y) + φ(y)φ(x) for every x, y ∈ A. This is equivalent to saying that φ(x 2 ) = φ(x) 2 for every x ∈ A. The following problem, due to I. Kaplansky, is still unsolved for the general Banach algebra case: Let A and B be unital Banach algebras and φ : A → B a unital, invertibility preserving linear mapping. Under what conditions of A and B is φ a Jordan homomorphism? The author’s honours project [24] served as an exposition of the GleasonKahane-Żelazko Theorem [7, Theorem 4], which provides an answer to Kaplansky’s problem in the case where B = C. In this dissertation we look at other special cases of Kaplansky’s problem, such as the case where A and B are von Neumann algberas, as solved by Aupetit [4, Theorem 1.3] and remark that his result holds for the more general case where A is any C ∗ -algebra that has the property that every self-adjoint element is the limit of a sequence of linear combinations of orthogonal idempotents in A, and B is a semi-simple Banach algebra. This result relies heavily on complex function theory, spectral theory and holomorphic functional calculus. We also provide detailed expositions of the work of Taylor [27] in which an operator calculus on undounded, closed linear operators is developed, and the work of Allan [1] in which a holomorphic functional calculus is defined for locally convex algebras.
- Full Text:
- Date Issued: 2019
Applying anthropological perspectives in criminal procedures involving murder in Port Elizabeth, 2000-2016
- Authors: Thornton, Jessica Leigh
- Date: 2019
- Subjects: Criminal procedures
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10948/44688 , vital:38161
- Description: With the spike of annual reported murders in South Africa, the country is continuing to climb the global rank of the world’s most violent countries. In 2016 alone, there were over nineteen thousand reported murders, equalling over fifty murders per day, with the Eastern Cape holding position as the province with the highest murder rate. Studies indicate that Port Elizabeth is the hardest hit by crime, adding up to 60% of all reported crimes in the province and despite the use of a ‘catch and convict’ only approach in criminal proceedings, violence and crime are still highly prevalent. Thus, overall the situation suggests that it may be beyond law enforcement control and even though the South African Police Service have taken some progressive steps in reforming procedures, generally, these have been too little and too late, as the reforms introduced are piecemeal and crisis driven. This thesis, therefore, proposes that additional approaches may be needed to improve investigations of the most pernicious crimes. Here, the focus is on the role of culture and social life in ‘murder-scapes’ with a critical contribution of the ‘habitus’ of murder allowing for the meaningful engagement with criminal acts, policing, sentencing, imprisonment and probation. In this regard, perspectives drawn from anthropology can possibly assist law enforcement officials in their steps of investigating a murder by providing a more ethnographic, holistic and integrated narrative in all areas of a criminal proceeding. An efficacious and constructive interpretation of the different subcultures crime scene processing, profiles development, testimony documentation and participation production with the police force and task teams can assist in redirecting and reappraising current practises that prove incompetent. That is, in attempting to review the current procedures conducted by law enforcers to identify how and where anthropological and ethnographical knowledge can be applied and successfully utilised, an assessment may aid officials in better investigative practises which could have implications for wider lenses making use of action, investigation, containment, prevention and rehabilitation. By advancing a deep understanding of the issue of murder in the South African context, implications for a wider, equally modernising and equally troubled society in the global South can be inferred.
- Full Text:
- Date Issued: 2019
- Authors: Thornton, Jessica Leigh
- Date: 2019
- Subjects: Criminal procedures
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10948/44688 , vital:38161
- Description: With the spike of annual reported murders in South Africa, the country is continuing to climb the global rank of the world’s most violent countries. In 2016 alone, there were over nineteen thousand reported murders, equalling over fifty murders per day, with the Eastern Cape holding position as the province with the highest murder rate. Studies indicate that Port Elizabeth is the hardest hit by crime, adding up to 60% of all reported crimes in the province and despite the use of a ‘catch and convict’ only approach in criminal proceedings, violence and crime are still highly prevalent. Thus, overall the situation suggests that it may be beyond law enforcement control and even though the South African Police Service have taken some progressive steps in reforming procedures, generally, these have been too little and too late, as the reforms introduced are piecemeal and crisis driven. This thesis, therefore, proposes that additional approaches may be needed to improve investigations of the most pernicious crimes. Here, the focus is on the role of culture and social life in ‘murder-scapes’ with a critical contribution of the ‘habitus’ of murder allowing for the meaningful engagement with criminal acts, policing, sentencing, imprisonment and probation. In this regard, perspectives drawn from anthropology can possibly assist law enforcement officials in their steps of investigating a murder by providing a more ethnographic, holistic and integrated narrative in all areas of a criminal proceeding. An efficacious and constructive interpretation of the different subcultures crime scene processing, profiles development, testimony documentation and participation production with the police force and task teams can assist in redirecting and reappraising current practises that prove incompetent. That is, in attempting to review the current procedures conducted by law enforcers to identify how and where anthropological and ethnographical knowledge can be applied and successfully utilised, an assessment may aid officials in better investigative practises which could have implications for wider lenses making use of action, investigation, containment, prevention and rehabilitation. By advancing a deep understanding of the issue of murder in the South African context, implications for a wider, equally modernising and equally troubled society in the global South can be inferred.
- Full Text:
- Date Issued: 2019
Applying anthropological perspectives in criminal procedures involving murder in Port Elizabeth, 2000-2016
- Authors: Thornton, Jessica Leigh
- Date: 2019
- Subjects: Murder -- South Africa -- Port Elizabeth , Crime -- South Africa -- Port Elizabeth Law enforcement -- South Africa -- Port Elizabeth Criminology -- South Africa -- Port Elizabeth
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10948/45238 , vital:38335
- Description: With the spike of annual reported murders in South Africa, the country is continuing to climb the global rank of the world’s most violent countries. In 2016 alone, there were over nineteen thousand reported murders, equalling over fifty murders per day, with the Eastern Cape holding position as the province with the highest murder rate. Studies indicate that Port Elizabeth is the hardest hit by crime, adding up to 60% of all reported crimes in the province and despite the use of a ‘catch and convict’ only approach in criminal proceedings, violence and crime are still highly prevalent. Thus, overall the situation suggests that it may be beyond law enforcement control and even though the South African Police Service have taken some progressive steps in reforming procedures, generally, these have been too little and too late, as the reforms introduced are piecemeal and crisis driven. This thesis, therefore, proposes that additional approaches may be needed to improve investigations of the most pernicious crimes. Here, the focus is on the role of culture and social life in ‘murder-scapes’ with a critical contribution of the ‘habitus’ of murder allowing for the meaningful engagement with criminal acts, policing, sentencing, imprisonment and probation. In this regard, perspectives drawn from anthropology can possibly assist law enforcement officials in their steps of investigating a murder by providing a more ethnographic, holistic and integrated narrative in all areas of a criminal proceeding. An efficacious and constructive interpretation of the different subcultures, crime scene processing, profiles development, testimony documentation and participation production with the police force and task teams can assist in redirecting and reappraising current practises that prove incompetent. That is, in attempting to review the current procedures conducted by law enforcers to identify how and where anthropological and ethnographical knowledge can be applied and successfully utilised, an assessment may aid officials in better investigative practises which could have implications for wider lenses making use of action, investigation, containment, prevention and rehabilitation. By advancing a deep understanding of the issue of murder in the South African context, implications for a wider, equally modernising and equally troubled society in the global South can be inferred.
- Full Text:
- Date Issued: 2019
- Authors: Thornton, Jessica Leigh
- Date: 2019
- Subjects: Murder -- South Africa -- Port Elizabeth , Crime -- South Africa -- Port Elizabeth Law enforcement -- South Africa -- Port Elizabeth Criminology -- South Africa -- Port Elizabeth
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10948/45238 , vital:38335
- Description: With the spike of annual reported murders in South Africa, the country is continuing to climb the global rank of the world’s most violent countries. In 2016 alone, there were over nineteen thousand reported murders, equalling over fifty murders per day, with the Eastern Cape holding position as the province with the highest murder rate. Studies indicate that Port Elizabeth is the hardest hit by crime, adding up to 60% of all reported crimes in the province and despite the use of a ‘catch and convict’ only approach in criminal proceedings, violence and crime are still highly prevalent. Thus, overall the situation suggests that it may be beyond law enforcement control and even though the South African Police Service have taken some progressive steps in reforming procedures, generally, these have been too little and too late, as the reforms introduced are piecemeal and crisis driven. This thesis, therefore, proposes that additional approaches may be needed to improve investigations of the most pernicious crimes. Here, the focus is on the role of culture and social life in ‘murder-scapes’ with a critical contribution of the ‘habitus’ of murder allowing for the meaningful engagement with criminal acts, policing, sentencing, imprisonment and probation. In this regard, perspectives drawn from anthropology can possibly assist law enforcement officials in their steps of investigating a murder by providing a more ethnographic, holistic and integrated narrative in all areas of a criminal proceeding. An efficacious and constructive interpretation of the different subcultures, crime scene processing, profiles development, testimony documentation and participation production with the police force and task teams can assist in redirecting and reappraising current practises that prove incompetent. That is, in attempting to review the current procedures conducted by law enforcers to identify how and where anthropological and ethnographical knowledge can be applied and successfully utilised, an assessment may aid officials in better investigative practises which could have implications for wider lenses making use of action, investigation, containment, prevention and rehabilitation. By advancing a deep understanding of the issue of murder in the South African context, implications for a wider, equally modernising and equally troubled society in the global South can be inferred.
- Full Text:
- Date Issued: 2019
Applying distributed ledger technology to digital evidence integrity
- Weilbach, William T, Motara, Yusuf, M
- Authors: Weilbach, William T , Motara, Yusuf, M
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/428960 , vital:72549 , https://ieeexplore.ieee.org/abstract/document/8732798
- Description: This paper examines the way in which blockchain technology can be used to improve the verification of integrity of evidence in digital forensics. Some background into digital forensic practices and blockchain technology are discussed to provide necessary context. A particular scalable method of verifying point-in-time existence of a piece of digital evidence, using the OpenTimestamps (OTS) service, is described, and tests are carried out to independently validate the claims made by the service. The results demonstrate that the OTS service is highly reliable with a zero false positive and false negative error rate for timestamp attestations, but that it is not suitable for timesensitive timestamping due to the variance of the accuracy of timestamps induced by block confirmation times in the Bitcoin blockchain.
- Full Text:
- Date Issued: 2019
- Authors: Weilbach, William T , Motara, Yusuf, M
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/428960 , vital:72549 , https://ieeexplore.ieee.org/abstract/document/8732798
- Description: This paper examines the way in which blockchain technology can be used to improve the verification of integrity of evidence in digital forensics. Some background into digital forensic practices and blockchain technology are discussed to provide necessary context. A particular scalable method of verifying point-in-time existence of a piece of digital evidence, using the OpenTimestamps (OTS) service, is described, and tests are carried out to independently validate the claims made by the service. The results demonstrate that the OTS service is highly reliable with a zero false positive and false negative error rate for timestamp attestations, but that it is not suitable for timesensitive timestamping due to the variance of the accuracy of timestamps induced by block confirmation times in the Bitcoin blockchain.
- Full Text:
- Date Issued: 2019
Arbuscular mycorrhizal fungi as a bio-indicator of soil health under agricultural management practices in South Africa
- Authors: Sekgota, Wendy Maphefo
- Date: 2019
- Subjects: Soils -- Quality -- South Africa , Soil fertility -- South Africa , Fungi in agriculture -- South Africa , Mycorrhizal fungi , Vesicular-arbuscular mycorrhizas , Fungi -- Spores , Soils -- Agricultural chemical content
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/72161 , vital:30011
- Description: This study investigated the activity of arbuscular mycorrhizal (AM) fungi as a potential biological indicator of soil health under conventional and conservation agricultural management in South Africa. An experimental trial consisting of three replicates plots under conventional and reduced tillage subdivided into twelve treatments of six crops and two fertilizer inputs was assessed over four growing seasons for various AM fungal parameters such as spore density, most probable number (MPN) of propagules percentage root colonisation and easily extractable glomalin (EEG). Cropping combinations were maize monoculture; maize soybean rotation; maize cowpea rotation; maize cowpea intercropping; maize oats intercropping and maize vetch intercropping. Resident AM fungal spore numbers and EEG protein levels were very low and no root colonization was recorded in the first two growing seasons. These findings prompted the need for the inoculation of the study site in the third growing season with a commercial AM fungal product (MycorootTM). Spore numbers, EEG concentrations and percentage root colonisation increased 8 weeks after inoculation but were significantly reduced in the fourth growing season that was not inoculated. MPN infectivity increased with inoculation particularly under conventional tillage and maize monoculture. Resident spore taxa were morphologically identified into three genera Gigaspora, Scutellospora, and Glomus. For the first two growing seasons, the maize roots were heavily colonized by a pathogenic fungus after mycorrhizal inoculation no evidence of pathogenic fungi was observed. In the fourth growing season which did not receive inoculation, root colonization started to decline. Reduced tillage, high fertilizer input combined with maize cowpea rotation (MC) and maize hairy vetch intercropping (Mv) had a significant effect (P = 0.01) on AM fungal spore numbers. Cropping systems and high fertilizer input had a significant effect on EEG concentrations in the second growing season. Overall, fertilizer application and crop type had implications for mycorrhizal activity. The soil health status in this study site was deemed low as measured by the impaired mycorrhizal activity due to agricultural management practices. Field inoculation combined with classical and molecular tools could provide a more realistic assessment of the effect of agricultural management practices on AM fungi as potential bioindicators of soil health. Therefore, AM fungi could be used as bioindicators of soil health under agricultural management practices in South African soil conditions.
- Full Text:
- Date Issued: 2019
- Authors: Sekgota, Wendy Maphefo
- Date: 2019
- Subjects: Soils -- Quality -- South Africa , Soil fertility -- South Africa , Fungi in agriculture -- South Africa , Mycorrhizal fungi , Vesicular-arbuscular mycorrhizas , Fungi -- Spores , Soils -- Agricultural chemical content
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/72161 , vital:30011
- Description: This study investigated the activity of arbuscular mycorrhizal (AM) fungi as a potential biological indicator of soil health under conventional and conservation agricultural management in South Africa. An experimental trial consisting of three replicates plots under conventional and reduced tillage subdivided into twelve treatments of six crops and two fertilizer inputs was assessed over four growing seasons for various AM fungal parameters such as spore density, most probable number (MPN) of propagules percentage root colonisation and easily extractable glomalin (EEG). Cropping combinations were maize monoculture; maize soybean rotation; maize cowpea rotation; maize cowpea intercropping; maize oats intercropping and maize vetch intercropping. Resident AM fungal spore numbers and EEG protein levels were very low and no root colonization was recorded in the first two growing seasons. These findings prompted the need for the inoculation of the study site in the third growing season with a commercial AM fungal product (MycorootTM). Spore numbers, EEG concentrations and percentage root colonisation increased 8 weeks after inoculation but were significantly reduced in the fourth growing season that was not inoculated. MPN infectivity increased with inoculation particularly under conventional tillage and maize monoculture. Resident spore taxa were morphologically identified into three genera Gigaspora, Scutellospora, and Glomus. For the first two growing seasons, the maize roots were heavily colonized by a pathogenic fungus after mycorrhizal inoculation no evidence of pathogenic fungi was observed. In the fourth growing season which did not receive inoculation, root colonization started to decline. Reduced tillage, high fertilizer input combined with maize cowpea rotation (MC) and maize hairy vetch intercropping (Mv) had a significant effect (P = 0.01) on AM fungal spore numbers. Cropping systems and high fertilizer input had a significant effect on EEG concentrations in the second growing season. Overall, fertilizer application and crop type had implications for mycorrhizal activity. The soil health status in this study site was deemed low as measured by the impaired mycorrhizal activity due to agricultural management practices. Field inoculation combined with classical and molecular tools could provide a more realistic assessment of the effect of agricultural management practices on AM fungi as potential bioindicators of soil health. Therefore, AM fungi could be used as bioindicators of soil health under agricultural management practices in South African soil conditions.
- Full Text:
- Date Issued: 2019
Archives and Records Management Programmes in selected Universities in South Africa: A Study of University of Fort Hare and Rhodes University
- Authors: Somniso, Zoleka
- Date: 2019
- Subjects: Records -- Management
- Language: English
- Type: Thesis , Masters , MSoc. Sci (Library and information science)
- Identifier: http://hdl.handle.net/10353/18280 , vital:42248
- Description: The study investigates the Archives and Records Management Programmes (ARMP) in the University of Fort Hare (UFH) and Rhodes University (RU). The task of managing huge quantities of records and archives material is not an easy task when people have to use limited resources. The Research Objectives of the this study was to find out types of records created, received and maintained by university archives and records management programmes at University of Fort Hare and Rhodes University. Establish the available infrastructure for ARMP at the UFH and RU. Find out the legislative and regulatory frameworks that govern the ARMP at the UFH and RU. Identify challenges if there are any facing ARMP at the UFH and Rhodes University. Interviews and questionnaires were two research instruments used in this study to collect data; additional data was collected by reading relevant documents gathered on both institutions and on their website. In this study, the sample was 26 respondents from both universities. The study dealt with administrative staff who deal with records management: Records managers/Officers and Archivists at both institutions. viii Data collected was coded and analysed using Statistical Package for Social Sciences (SPSS) and the findings were presented using pie chart , graphs. The triangulation approaches involves using more than one method to collect data and it is a way of assuring the validity of research with variety of methods to collect data. Findings revealed that respondents were unaware of ARMP in the university. And also some of the findings were the infrastructural needs such as the Lack of records storage, space, Records Preservation facilities (RH, Light), Personnel Training and Development. The challenges facing ARMP in universities includes: a lack of programmes to manage records and archives material, absence of policy that regulates archives and records keeping in the universities understudy, the existing infrastructure at hand cannot meet the requirements for regulatory framework on records and archives management. Based on these challenges mentioned above, the study recommended that both institutions should improve their infrastructure as to be able to preserve the archival material. Training and retraining of staff among others should include use of technology, filing, records creation, maintenance and disposition
- Full Text:
- Date Issued: 2019
- Authors: Somniso, Zoleka
- Date: 2019
- Subjects: Records -- Management
- Language: English
- Type: Thesis , Masters , MSoc. Sci (Library and information science)
- Identifier: http://hdl.handle.net/10353/18280 , vital:42248
- Description: The study investigates the Archives and Records Management Programmes (ARMP) in the University of Fort Hare (UFH) and Rhodes University (RU). The task of managing huge quantities of records and archives material is not an easy task when people have to use limited resources. The Research Objectives of the this study was to find out types of records created, received and maintained by university archives and records management programmes at University of Fort Hare and Rhodes University. Establish the available infrastructure for ARMP at the UFH and RU. Find out the legislative and regulatory frameworks that govern the ARMP at the UFH and RU. Identify challenges if there are any facing ARMP at the UFH and Rhodes University. Interviews and questionnaires were two research instruments used in this study to collect data; additional data was collected by reading relevant documents gathered on both institutions and on their website. In this study, the sample was 26 respondents from both universities. The study dealt with administrative staff who deal with records management: Records managers/Officers and Archivists at both institutions. viii Data collected was coded and analysed using Statistical Package for Social Sciences (SPSS) and the findings were presented using pie chart , graphs. The triangulation approaches involves using more than one method to collect data and it is a way of assuring the validity of research with variety of methods to collect data. Findings revealed that respondents were unaware of ARMP in the university. And also some of the findings were the infrastructural needs such as the Lack of records storage, space, Records Preservation facilities (RH, Light), Personnel Training and Development. The challenges facing ARMP in universities includes: a lack of programmes to manage records and archives material, absence of policy that regulates archives and records keeping in the universities understudy, the existing infrastructure at hand cannot meet the requirements for regulatory framework on records and archives management. Based on these challenges mentioned above, the study recommended that both institutions should improve their infrastructure as to be able to preserve the archival material. Training and retraining of staff among others should include use of technology, filing, records creation, maintenance and disposition
- Full Text:
- Date Issued: 2019