- Title
- Indium phthalocyanines
- Creator
- Pinar, Sen
- Creator
- Mack, John
- Creator
- Nyokong, Tebello
- Subject
- To be catalogued
- Date Issued
- 2022
- Date
- 2022
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/229998
- Identifier
- vital:49731
- Identifier
- xlink:href="https://doi.org/10.1016/j.molstruc.2021.131850"
- Description
- In this study, the photodynamic antimicrobial activities of a series of new tetra-substituted indium phthalocyanine (InPc) complexes are assessed. An aldehyde substituted complex (2) was initially prepared, which was converted through a condensatioreaction to an imine-pyrrolidine substituted complex (3), which in turn was quaternized to form a tetracationic species (4). Favorable photophysicochemical properties were obtained by incorporating a heavy In(III) ion into the central cavity. Aggregation studies revealed that 2–4 remain non-aggregated in DMSO at concentration below 25 µM. The photodeactivation of S.aureus and E.coli was studied. Log reduction values > 9.0 were obtained for cationic InPc 4 after 30 min of incubation and exposure to light for 75 min.
- Format
- computer
- Format
- online resource
- Format
- application/pdf
- Format
- 1 online resource (9 pages)
- Format
- Publisher
- Elsevier
- Language
- English
- Relation
- Journal of Molecular Structure
- Relation
- Sen, P., Mack, J. and Nyokong, T., 2022. Indium phthalocyanines: Comparative photophysicochemical properties and photodynamic antimicrobial activities against Staphylococcus aureus and Escherichia coli. Journal of Molecular Structure, 1250, p.131850
- Relation
- Journal of Molecular Structure volume 1250 p. 131850 2022 0022-2860
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the Elsevier Terms and Conditions Statement (https://www.elsevier.com/legal/elsevier-website-terms-and-conditions)
- Rights
- Closed Access
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Collections
Mack, John (Associate Prof)
RU DST/NRF SARChI for Medicinal Chemistry and Nanotechnology
Nyokong, Tebello (Distinguished Professor)
RU Department of Chemistry
SDG 03. Good Health and Well-Being
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | SOURCE1 | Indium phthalocyanines.pdf | 802 KB | Adobe Acrobat PDF | View Details Download |