Composition portfolio
- Authors: Musambasi, Richie Andile
- Date: 2024-10-11
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/466094 , vital:76684
- Description: Indigenous Zimbabwean music is complex in its make up and reveals spiritual beliefs, modes of expression, communication patterns, and forms of entertainment. The goal of this composition portfolio is to create pieces that are imbued with the spirit of indigenous Zimbabwean music making as passed on from father to son. The pieces composed include thorough-composed (pre-determined) solo and ensemble frameworks using mostly marimbas based largely on Shona scales and tuning, but also adding mbira, hosho and djembe. All of this is presented within complex structural manipulations that include African and some Western elements of formal music structure. The compositions feature two interlocking parts, known as kushaura and kutsinhira (call and respond), which are traditionally played in a simultaneous manner by two or more musicians. In this portfolio, these voices are spread across a range of players where the interplay between the parts produces complex polyphonic and polyrhythmic musical relationships. The compositions explore modal changes which add excitement, variety and an extra layer of complexity to the pieces. The final artefact is presented as a multimedia submission recorded as a documentary in real time, which is a representation of the embodied making of the music, central to this project. As music was passed down through folk tales, religious gatherings, rock paintings and sources of art, the narration is the key element in expressing that knowledge dissemination is not only text bound, but also embodied and orally shared. , Thesis (MA) -- Faculty of Humanities, Music and Musicology, 2024
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- Date Issued: 2024-10-11
A Comparative Analysis of PSA Trends of Conventional vs Hypo-fractionated External Beam Radiotherapy for the Treatment of Localised Prostate Cancer at Frere Hospital
- Authors: Mistry, Himal
- Date: 2023-10
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/12906 , vital:76177
- Description: External beam radiotherapy with a moderate hypofractionated regimen has largely replaced conventional schedules. The change in regimen is based on the premise that prostate cancer, due to its low the alpha/beta ratio, demonstrates a higher sensitivity to a larger dose per fraction of radiation. Prostate Specific Antigen (PSA) is a specific indicator of prostate cancer treatment outcomes. The serum PSA trend is an indication of treatment response and risk for relapse. The time to nadir and the value of the PSA nadir are important predictors of biochemical control or failure. The lower the PSA level, the more durable the probability of maintained biochemical disease free survival. This study focuses on the biochemical control of patients treated with two different fractionation regimens at Frere Hospital. Aim To illustrate that the use of a moderate hypofractionated regimen for the treatment of intermediate and high risk prostate cancer is non inferior to a conventional regimen. Methodology The study took place at the department of radiation oncology, Frere Hospital, East London, Eastern Cape, South Africa. The study population consisted of 26 patients treated with conventional fractionation (2.00Gy x 36 fractions) in 2018 and 36 patients treated with the newly adopted hypofractionated regimen (3.00Gy x 20 fractions) in 2019. A comparison is made of the post treatment PSA trend over a 24 month period. Impact of study The study is projected to support the change in fractionation regimens at an institutional level. 2 Results: 41.9% of patients were enrolled in the conventional regimen, 58.1% were enrolled in the moderately hypo-fractionated arm. The participants were classified into high risk and intermediate risk in the two treatment arms and these were distributed equally. There was a clear decline in the serum PSA values over the two-year follow-up period. All four groups showed a similar pattern in that from the baseline to the first quarter, there was a sharp decline in the serum PSA values and this was significant for all four groups , Thesis (Masters) -- Faculty of Medicine and Health Sciences, 2023
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- Date Issued: 2023-10