Overcoming hurdles facing researchers in Africa
- Nyokong, Tebello, Ngoy, Bokolombe P, Amuhaya, Edith K
- Authors: Nyokong, Tebello , Ngoy, Bokolombe P , Amuhaya, Edith K
- Date: 2021
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/177511 , vital:42828 , https://doi.org/10.1038/s41563-021-00961-0
- Description: Several countries on the African continent recognize that a transition to a knowledge-based economic model would stimulate growth and enable scientific independence. Investing in new knowledge would drive the formation of highly qualified professionals and the use of advanced technologies, triggering in return positive economic trends. Importantly, a knowledge-based economy that values the impact of science on society would help reversing the migration of skilled workers and lead to brain gain.
- Full Text:
- Date Issued: 2021
- Authors: Nyokong, Tebello , Ngoy, Bokolombe P , Amuhaya, Edith K
- Date: 2021
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/177511 , vital:42828 , https://doi.org/10.1038/s41563-021-00961-0
- Description: Several countries on the African continent recognize that a transition to a knowledge-based economic model would stimulate growth and enable scientific independence. Investing in new knowledge would drive the formation of highly qualified professionals and the use of advanced technologies, triggering in return positive economic trends. Importantly, a knowledge-based economy that values the impact of science on society would help reversing the migration of skilled workers and lead to brain gain.
- Full Text:
- Date Issued: 2021
Allosteric site modulators: a case study for falcipains as malarial drug targets
- Musyoka, Thommas, Tastan Bishop, Özlem
- Authors: Musyoka, Thommas , Tastan Bishop, Özlem
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/162699 , vital:40974 , https://doi.org/10.21955/gatesopenres.1116459.1
- Description: Fighting against malaria is a never-ending battle. Plasmodium parasites continuously develop resistance to the drugs used against them including the artemisinin-based combination therapies as observed recently in Southeast Asia. The main concern now is whether the resistant parasite strains spread to Africa, where most malaria cases are located. To prevent this, we need to think outside the box. To date, there is no allosteric drug for malaria. Hence, allosteric drug targeting sites and modulators might be a new hope for malarial treatment. In Plasmodium falciparum two cysteine proteases, falcipain-2 (FP-2) and falcipain-3 (FP-3), have been identified as the main hemoglobinases, and are considered as attractive drug targets.
- Full Text:
- Date Issued: 2019
- Authors: Musyoka, Thommas , Tastan Bishop, Özlem
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/162699 , vital:40974 , https://doi.org/10.21955/gatesopenres.1116459.1
- Description: Fighting against malaria is a never-ending battle. Plasmodium parasites continuously develop resistance to the drugs used against them including the artemisinin-based combination therapies as observed recently in Southeast Asia. The main concern now is whether the resistant parasite strains spread to Africa, where most malaria cases are located. To prevent this, we need to think outside the box. To date, there is no allosteric drug for malaria. Hence, allosteric drug targeting sites and modulators might be a new hope for malarial treatment. In Plasmodium falciparum two cysteine proteases, falcipain-2 (FP-2) and falcipain-3 (FP-3), have been identified as the main hemoglobinases, and are considered as attractive drug targets.
- Full Text:
- Date Issued: 2019
The "old-new" challenges of water, sanitation and bioremediation in developing countries
- Authors: Tandlich, Roman
- Date: 2014
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/75982 , vital:30489 , DOI: 10.4172/2155-6199.1000e152
- Description: Developing countries face challenges in the development of infrastructure and population growth. These lead to “side-effects" such as uncontrolled urbanization and the fact that basic services such as water and sanitation are lagging behind the actual needs on the ground. Historical challenges, lack of skilled staff and often lack of sustained funding are some of the reasons for the status quo. Extent of water and sanitation coverage often forces national and local governments to install the minimum-standard solutions, e.g. the ventilated improved pit latrines. This improves the public health status in the short-term, but causes problem in the long run due to the lack of regular maintenance such as through lack emptying of pits. Sometimes, construction of these facilities is of inferior standard. Pits are often built without lining or zero consideration is given to the local conditions in terms of soil properties, water table and the number of toilet users.
- Full Text:
- Date Issued: 2014
- Authors: Tandlich, Roman
- Date: 2014
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/75982 , vital:30489 , DOI: 10.4172/2155-6199.1000e152
- Description: Developing countries face challenges in the development of infrastructure and population growth. These lead to “side-effects" such as uncontrolled urbanization and the fact that basic services such as water and sanitation are lagging behind the actual needs on the ground. Historical challenges, lack of skilled staff and often lack of sustained funding are some of the reasons for the status quo. Extent of water and sanitation coverage often forces national and local governments to install the minimum-standard solutions, e.g. the ventilated improved pit latrines. This improves the public health status in the short-term, but causes problem in the long run due to the lack of regular maintenance such as through lack emptying of pits. Sometimes, construction of these facilities is of inferior standard. Pits are often built without lining or zero consideration is given to the local conditions in terms of soil properties, water table and the number of toilet users.
- Full Text:
- Date Issued: 2014
The gap between what 'ought' to be and what students want
- Authors: Boshoff, Priscilla A
- Date: 2010
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/70812 , vital:29747
- Description: There’s no curriculum! There’s no curriculum!” The young man in the focus group was so frustrated that he had to repeat himself, not just once, but several times. I had just asked the group what their feelings were about their second-year coursework. His sentiments were echoed by many of the students in the group, all of whom had passed the rigorous application process into second year at Rhodes University’s School of Journalism and Media Studies.
- Full Text:
- Date Issued: 2010
- Authors: Boshoff, Priscilla A
- Date: 2010
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/70812 , vital:29747
- Description: There’s no curriculum! There’s no curriculum!” The young man in the focus group was so frustrated that he had to repeat himself, not just once, but several times. I had just asked the group what their feelings were about their second-year coursework. His sentiments were echoed by many of the students in the group, all of whom had passed the rigorous application process into second year at Rhodes University’s School of Journalism and Media Studies.
- Full Text:
- Date Issued: 2010
The Dakar Conference: a different perspective
- Authors: Moorcroft, E K
- Date: 1987-11
- Subjects: Apartheid -- South Africa , South Africa -- Politics and government , Government Resistance to – South Africa , Dakar Conference (1987, Dakar)
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/57784 , vital:26989 , This item is held at the Cory Library for Humanities Research at Rhodes University. For further information contact cory@ru.ac.za. The digitisation of this image was made possible through a generous grant received from the Andrew W. Mellon Foundation 2014-2017.
- Description: E.K. Moorcroft's article on the Dakar Conference - the political discussions held in Dakar, Senegal, between the 9th and 12th of July 1987, between members of IDASA and the ANC. Article appeared in the journal titled "Reality: a journal of liberal and radical opinion", vol. 19, no. 6, issue dated November 1987.
- Full Text:
- Date Issued: 1987-11
- Authors: Moorcroft, E K
- Date: 1987-11
- Subjects: Apartheid -- South Africa , South Africa -- Politics and government , Government Resistance to – South Africa , Dakar Conference (1987, Dakar)
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/57784 , vital:26989 , This item is held at the Cory Library for Humanities Research at Rhodes University. For further information contact cory@ru.ac.za. The digitisation of this image was made possible through a generous grant received from the Andrew W. Mellon Foundation 2014-2017.
- Description: E.K. Moorcroft's article on the Dakar Conference - the political discussions held in Dakar, Senegal, between the 9th and 12th of July 1987, between members of IDASA and the ANC. Article appeared in the journal titled "Reality: a journal of liberal and radical opinion", vol. 19, no. 6, issue dated November 1987.
- Full Text:
- Date Issued: 1987-11
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