- Title
- Preparation, characterization and optimization of carbamazepine based pellets prepared by extrusion-spheronization technique
- Creator
- Makoni, Kudzai Gabriella
- Subject
- Carbamazepine
- Subject
- Pharmacokinetics
- Subject
- Anticonvulsants
- Subject
- Drugs -- Controlled release
- Subject
- Drugs -- Dosage forms
- Subject
- Tablets (Medicine)
- Subject
- Drugs -- Administration
- Subject
- High performance liquid chromatography
- Subject
- International Conference on Harmonisation
- Subject
- Experimental design
- Date Issued
- 2020-04
- Date
- 2020-04
- Type
- Thesis
- Type
- Masters
- Type
- MSc (Pharmacy)
- Identifier
- http://hdl.handle.net/10962/140478
- Identifier
- vital:37893
- Description
- Carbamazepine (CBZ) is an oral antiepileptic drug (AED) that is prescribed as a first-line treatment for partial seizures. CBZ is a class II compound according to the Biopharmaceutical Classification System (BCS), hence it exhibits low aqueous solubility and high gastrointestinal tract (GIT) permeability...
- Format
- 216 pages
- Format
- Publisher
- Rhodes University
- Publisher
- Faculty of Pharmacy, Pharmacy
- Language
- English
- Rights
- Makoni, Kudzai Gabriella
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View Details Download | SOURCE1 | MAKONI-MSC-TR125.pdf | 80 KB | Adobe Acrobat PDF | View Details Download |