Evaluating the implementation of the principles of good governance in Zimbabwe local government system : a case of Marondera local municipality
- Authors: Muswaka, Phyllis
- Date: 2014
- Subjects: Local government -- Zimbabwe Public administration -- Zimbabwe
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/13068 , vital:39453
- Description: Participatory budgeting currently occupies centre stage in Public and Municipal financial management Acts. The principle of participatory budgeting ushers in a broader public forum in which crucial principles in Public financial management such as accountability and transparency are observed, thereby automatically ensuring effective governance. The efficacy of participatory budgeting is to improve service delivery through opening up structures that will combat the spread of mal administrative practices such as corruption and financial fraud whilst enhancing democratic participation and upholding the rule of law by fostering transparency and accountability and making the governments more responsive to the needs of the people. The main objective of this study is to explore the pernicious effects of having limited citizen participation in Public finance management. It seeks to examine whether the poor service delivery by local municipalities can be attributed to the lack of effective citizen participation. This will be done through assessing whether the seeds of participatory budgeting have led to the fruits of efficient and effective service delivery in the public sector both in theory and in practice at Nkonkobe local municipality. It has been discovered that the inability to provide effective service delivery is a complex challenge facing many municipalities in South Africa, and although such a situation has been co-determined by many other factors including financial restraints, the root cause of service delivery incapability’s can be traced back to weather the citizens are actually participating in the management of public finances through participatory budgeting or not. More often than not, the failure to accommodate the citizens in local government affairs has been the spark that has been responsible for setting alight strikes and service delivery protest marches in most of South Africa’s Provinces. However, due to this, this study aims to reveal that participatory budgeting is an ambitious issue that requires local authorities to focus on in order to improve service delivery through embracing active citizen participation. Recommendations as well as consequences of lack of citizen participation in the budget process were thereby highlighted.
- Full Text:
- Date Issued: 2014
- Authors: Muswaka, Phyllis
- Date: 2014
- Subjects: Local government -- Zimbabwe Public administration -- Zimbabwe
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10353/13068 , vital:39453
- Description: Participatory budgeting currently occupies centre stage in Public and Municipal financial management Acts. The principle of participatory budgeting ushers in a broader public forum in which crucial principles in Public financial management such as accountability and transparency are observed, thereby automatically ensuring effective governance. The efficacy of participatory budgeting is to improve service delivery through opening up structures that will combat the spread of mal administrative practices such as corruption and financial fraud whilst enhancing democratic participation and upholding the rule of law by fostering transparency and accountability and making the governments more responsive to the needs of the people. The main objective of this study is to explore the pernicious effects of having limited citizen participation in Public finance management. It seeks to examine whether the poor service delivery by local municipalities can be attributed to the lack of effective citizen participation. This will be done through assessing whether the seeds of participatory budgeting have led to the fruits of efficient and effective service delivery in the public sector both in theory and in practice at Nkonkobe local municipality. It has been discovered that the inability to provide effective service delivery is a complex challenge facing many municipalities in South Africa, and although such a situation has been co-determined by many other factors including financial restraints, the root cause of service delivery incapability’s can be traced back to weather the citizens are actually participating in the management of public finances through participatory budgeting or not. More often than not, the failure to accommodate the citizens in local government affairs has been the spark that has been responsible for setting alight strikes and service delivery protest marches in most of South Africa’s Provinces. However, due to this, this study aims to reveal that participatory budgeting is an ambitious issue that requires local authorities to focus on in order to improve service delivery through embracing active citizen participation. Recommendations as well as consequences of lack of citizen participation in the budget process were thereby highlighted.
- Full Text:
- Date Issued: 2014
Synthesis of novel inhibitors of 1-Deoxy-D-xylulose-5-phosphate reductoisomerase as potential anti-malarial lead compounds
- Authors: Mutorwa, Marius Kudumo
- Date: 2011
- Subjects: Antimalarials -- Development Plasmodium falciparum Malaria -- Chemotherapy Drug development Lead compounds Phosphonates Phosphonic acids Ligands
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:4372 , http://hdl.handle.net/10962/d1005037
- Description: This research has focused on the development of novel substrate mimics as potential DXR inhibitors of 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR), an essential enzyme in the mevalonate-independent pathway for the biosynthesis of isoprenoids in Plasmodium falciparum. DXR mediates the isomerisation and reduction of 1-deoxy-D-xylulose-5-phosphate (DOXP) into 2C-methyl-D-erithrytol 4-phosphate (MEP) and has been validated as an attractive target for the development of novel anti-malarial chemotherapeutic agents. Reaction of various amines with specially prepared 4-phosphonated crotonic acid in the presence of the peptide coupling reagent, 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC), has afforded a series of amido-phosphonate esters in moderate to good yields (48% - 73%) which, using a RuCl₃/CeCl₃/NaIO₄ catalyst system, have been dihydroxylated to furnish the dihydroxy-amido phosphonate ester pro-drugs; subsequent hydrolysis under microwave irradiation has afforded the corresponding phosphonic acids. A second series of potential inhibitors viz., 3-substituted aniline-derived phosphonate esters, their corresponding phosphonic acids and mono-sodium salts, have also been successfully synthesised. In these compounds, the essential functional groups are separated by one, two, three or four methylene groups, Deprotonation of the 3-substituted aniline substrates, followed by reaction with the appropriate ω-chloroalkanoyl chloride produced the ω-chloroamide intermediates, which were subjected to the Michaelis-Arbuzov reaction to afford the diethyl phosphonate esters in moderate to good yields (48% - 74%). Microwave-assisted TMSBrmediated cleavage of the phosphonate esters furnished the phosphonic acids, neutralisation of which afforded the mono-sodium salts. Furan-derived phosphate esters and phosphonic acids have been prepared as conformationally-restricted DOXP analogues. Functionalization at C-5 of the trityl-protected furan was achieved using the Vilsmeier-Haack formylation and Friedel-Crafts acylation reactions and, following de-tritylation, phosphorylation and oximation, using hydroxylamine hydrochloride, the novel oxime derivatives have been isolated as a third series of potential DXR inhibitors in very good yields (87% - 96%). Finally, in order to exploit an additional binding pocket in the PƒDXR active site, a series of N-benzylated phosphoramidic derivatives were obtained in seven steps from the starting material, diethyl phosphoramidate. The known inhibitors, fosmidomycin and its acetyl derivative FR900098, were also successfully synthesised as standards for STD-NMR binding and inhibition assays. In all, over 200 compounds (136 novel) have been prepared and appropriately characterised using 1-and 2-D NMR and IR spectroscopic analysis and, where necessary, HRMS or combustion analysis. Saturation Transfer Difference (STD) protein-NMR experiments, undertaken using selected compounds, have revealed binding of most of the ligands examined to EcDXR. Computersimulated docking studies have also been used to explore the preferred ligand-binding conformations and interactions between the ligands and essential DXR active-site residues, while DXR-enzyme inhibition assays of selected synthesised ligands have revealed certain patterns of inhibitory activity.
- Full Text:
- Date Issued: 2011
- Authors: Mutorwa, Marius Kudumo
- Date: 2011
- Subjects: Antimalarials -- Development Plasmodium falciparum Malaria -- Chemotherapy Drug development Lead compounds Phosphonates Phosphonic acids Ligands
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:4372 , http://hdl.handle.net/10962/d1005037
- Description: This research has focused on the development of novel substrate mimics as potential DXR inhibitors of 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR), an essential enzyme in the mevalonate-independent pathway for the biosynthesis of isoprenoids in Plasmodium falciparum. DXR mediates the isomerisation and reduction of 1-deoxy-D-xylulose-5-phosphate (DOXP) into 2C-methyl-D-erithrytol 4-phosphate (MEP) and has been validated as an attractive target for the development of novel anti-malarial chemotherapeutic agents. Reaction of various amines with specially prepared 4-phosphonated crotonic acid in the presence of the peptide coupling reagent, 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC), has afforded a series of amido-phosphonate esters in moderate to good yields (48% - 73%) which, using a RuCl₃/CeCl₃/NaIO₄ catalyst system, have been dihydroxylated to furnish the dihydroxy-amido phosphonate ester pro-drugs; subsequent hydrolysis under microwave irradiation has afforded the corresponding phosphonic acids. A second series of potential inhibitors viz., 3-substituted aniline-derived phosphonate esters, their corresponding phosphonic acids and mono-sodium salts, have also been successfully synthesised. In these compounds, the essential functional groups are separated by one, two, three or four methylene groups, Deprotonation of the 3-substituted aniline substrates, followed by reaction with the appropriate ω-chloroalkanoyl chloride produced the ω-chloroamide intermediates, which were subjected to the Michaelis-Arbuzov reaction to afford the diethyl phosphonate esters in moderate to good yields (48% - 74%). Microwave-assisted TMSBrmediated cleavage of the phosphonate esters furnished the phosphonic acids, neutralisation of which afforded the mono-sodium salts. Furan-derived phosphate esters and phosphonic acids have been prepared as conformationally-restricted DOXP analogues. Functionalization at C-5 of the trityl-protected furan was achieved using the Vilsmeier-Haack formylation and Friedel-Crafts acylation reactions and, following de-tritylation, phosphorylation and oximation, using hydroxylamine hydrochloride, the novel oxime derivatives have been isolated as a third series of potential DXR inhibitors in very good yields (87% - 96%). Finally, in order to exploit an additional binding pocket in the PƒDXR active site, a series of N-benzylated phosphoramidic derivatives were obtained in seven steps from the starting material, diethyl phosphoramidate. The known inhibitors, fosmidomycin and its acetyl derivative FR900098, were also successfully synthesised as standards for STD-NMR binding and inhibition assays. In all, over 200 compounds (136 novel) have been prepared and appropriately characterised using 1-and 2-D NMR and IR spectroscopic analysis and, where necessary, HRMS or combustion analysis. Saturation Transfer Difference (STD) protein-NMR experiments, undertaken using selected compounds, have revealed binding of most of the ligands examined to EcDXR. Computersimulated docking studies have also been used to explore the preferred ligand-binding conformations and interactions between the ligands and essential DXR active-site residues, while DXR-enzyme inhibition assays of selected synthesised ligands have revealed certain patterns of inhibitory activity.
- Full Text:
- Date Issued: 2011
A history of the South African police in Port Elizabeth, 1913-1956
- Authors: Watson, Kelvin Innes
- Date: 2000
- Subjects: Police -- South Africa -- Eastern Cape South African Police -- South Africa -- Port Elizabeth -- History Police -- South Africa -- Port Elizabeth -- History
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:2570 , http://hdl.handle.net/10962/d1002423
- Description: This thesis investigates the policing activities of the South African Police (SAP) in Port Elizabeth from the formation of the SAP in 1913 to the creation of two separate police districts in the city in 1956. It begins with the recruitment and training of police personnel, outlining the difficulty in obtaining sufficient white recruits for most of the period while at the same time stressing the ease with which the Force was able to obtain black recruits. The preponderance of Afrikaner policemen serving in Port Elizabeth from the 1920s onwards is made clear, as is the para-military nature of the SAP, which was maintained and reinforced as a result of training methods and the process of socialisation. As state servants, police personnel were expected to serve loyally and obediently a state becoming increasingly repressive towards its black citizens. Generally inadequate conditions of service remained the norm throughout the period yet the SAP’s commitment to the state never wavered, bar one isolated, short-lived incidence. The administration and functioning of policing in Port Elizabeth is explored by focussing on specific organisational features pertinent to the city and the changes wrought by the police hierarchy to deal with the city’s demographic and spatial expansion. The SAP tended to employ three different forms of policing in the city as a result of its apartheid-driven agenda which compelled it to differentiate between the various population groups in terms of maintaining law and order. The privileged white community experienced routine, civil policing whereas the black community was policed largely in a socially and politically oppressive manner; this was in line with government policy. On the whole, however, the more brutal and sinister nature of policing was yet to come to the fore although this thesis does point towards the increasingly repressive nature of policing in South Africa during the apartheid era.
- Full Text:
- Date Issued: 2000
- Authors: Watson, Kelvin Innes
- Date: 2000
- Subjects: Police -- South Africa -- Eastern Cape South African Police -- South Africa -- Port Elizabeth -- History Police -- South Africa -- Port Elizabeth -- History
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:2570 , http://hdl.handle.net/10962/d1002423
- Description: This thesis investigates the policing activities of the South African Police (SAP) in Port Elizabeth from the formation of the SAP in 1913 to the creation of two separate police districts in the city in 1956. It begins with the recruitment and training of police personnel, outlining the difficulty in obtaining sufficient white recruits for most of the period while at the same time stressing the ease with which the Force was able to obtain black recruits. The preponderance of Afrikaner policemen serving in Port Elizabeth from the 1920s onwards is made clear, as is the para-military nature of the SAP, which was maintained and reinforced as a result of training methods and the process of socialisation. As state servants, police personnel were expected to serve loyally and obediently a state becoming increasingly repressive towards its black citizens. Generally inadequate conditions of service remained the norm throughout the period yet the SAP’s commitment to the state never wavered, bar one isolated, short-lived incidence. The administration and functioning of policing in Port Elizabeth is explored by focussing on specific organisational features pertinent to the city and the changes wrought by the police hierarchy to deal with the city’s demographic and spatial expansion. The SAP tended to employ three different forms of policing in the city as a result of its apartheid-driven agenda which compelled it to differentiate between the various population groups in terms of maintaining law and order. The privileged white community experienced routine, civil policing whereas the black community was policed largely in a socially and politically oppressive manner; this was in line with government policy. On the whole, however, the more brutal and sinister nature of policing was yet to come to the fore although this thesis does point towards the increasingly repressive nature of policing in South Africa during the apartheid era.
- Full Text:
- Date Issued: 2000
Aspekte van die prosa van Boerneef met spesifieke verwysing na die bundel Boplaas
- Authors: Meintjes, William Godfrey
- Date: 1989
- Subjects: Boerneef, 1897-1967 , Boplaas
- Language: Afrikaans
- Type: Thesis , Doctoral , PhD
- Identifier: vital:3570 , http://hdl.handle.net/10962/d1002093
- Description: This thesis is a report on a "rereading" (in the sense in which Roland Barthes uses the word) of the short texts of Boerneef (Izak Wilhelmus van der Merwe 1897-1967) published under the title Boplaas in 1938. Boerneef's prose is explored with specific reference to this one volume. The unity of the volume of texts is examined and textual indications of relations with other texts in the oeuvre are explored. In this way the thesis indicates how transtextuality determines meaning both in the individual texts as well as in the volume as a whole. The process of (re)reading in this thesis traces how, as a result of the exploration of the textual elements, a Boplaas code is generated. This Boplaas code signifies both the space and the ethos of Boplaas. Paternalism, feudalism and racism manifest themselves as important aspects of the ethos. The social disintegration which is endemic in this ethos is not caused, but merely accelerated by external impulses. The analysis indicates how, as a result of the specific organization of the narrative material, the text questions the feudal status quo. A process of demythologising of the vroegre boere-paradijs is therefore already present in the earliest Boerneef texts. However, the examination of Boerneef's prose also indicates that these texts go beyond the socio-politico-economic aspects by encoding the existential aspects of man's existence. , Hierdie proefskrif is die vers lag van 'n "rereading" (in die Barthesiaanse sin) van Boerneef (Izak Wi lhelmus van der Merwe 1897- 1967) se bundel Boplaas (1938). Die prosa van Boerneef word verken met spesifieke toespitsing op die een bundel . Die bundel-eenheid word ondersoek en tekstuele leidrade wat geledinge met ander tekste in die oeuvre aandui , word gevolg. Hierdeur word aangetoon hoe die betekenis en die be-tekenisprosesse van die tekste onderling, en die bundel as 'n geheel, op transtekstuele samehang berus. In hierdie leesproses word nagegaan hoe, deur middel van die ontginning van die tekstuele elemente, 'n Boplaas-kode in die narratiewe proses tot stand kom. Hierdie Boplaas-kode beteken 'n Boplaas-ruimte asook 'n Boplaas-etos. Paternalisme, feodalisme en rassisme word as belangrike aspekte van hierdie bestel geenkodeer en die tekste toon aan dat sosiale versplintering endemies aan die betrokke orde is en slegs deur impulse van buite verhaas word. In die bundel-analise word aangetoon hoe, as gevolg van die organisasie van die vertel stof, hierdie bundel bevraagtekenend ten opsigte van die feodale status quo staan. As gevolg hiervan is daar dus alreeds in die vroegste prosa van Boerneef 'n demitologisering van die "vroegre boere- paradijs" ingebed. Die ondersoek toon egter ook aan dat die Boplaas-tekste by die sosiopolitiko- ekonomiese dimensies verby óók die eksistensële aspekte van die mens se betstaan be-teken.
- Full Text:
- Date Issued: 1989
- Authors: Meintjes, William Godfrey
- Date: 1989
- Subjects: Boerneef, 1897-1967 , Boplaas
- Language: Afrikaans
- Type: Thesis , Doctoral , PhD
- Identifier: vital:3570 , http://hdl.handle.net/10962/d1002093
- Description: This thesis is a report on a "rereading" (in the sense in which Roland Barthes uses the word) of the short texts of Boerneef (Izak Wilhelmus van der Merwe 1897-1967) published under the title Boplaas in 1938. Boerneef's prose is explored with specific reference to this one volume. The unity of the volume of texts is examined and textual indications of relations with other texts in the oeuvre are explored. In this way the thesis indicates how transtextuality determines meaning both in the individual texts as well as in the volume as a whole. The process of (re)reading in this thesis traces how, as a result of the exploration of the textual elements, a Boplaas code is generated. This Boplaas code signifies both the space and the ethos of Boplaas. Paternalism, feudalism and racism manifest themselves as important aspects of the ethos. The social disintegration which is endemic in this ethos is not caused, but merely accelerated by external impulses. The analysis indicates how, as a result of the specific organization of the narrative material, the text questions the feudal status quo. A process of demythologising of the vroegre boere-paradijs is therefore already present in the earliest Boerneef texts. However, the examination of Boerneef's prose also indicates that these texts go beyond the socio-politico-economic aspects by encoding the existential aspects of man's existence. , Hierdie proefskrif is die vers lag van 'n "rereading" (in die Barthesiaanse sin) van Boerneef (Izak Wi lhelmus van der Merwe 1897- 1967) se bundel Boplaas (1938). Die prosa van Boerneef word verken met spesifieke toespitsing op die een bundel . Die bundel-eenheid word ondersoek en tekstuele leidrade wat geledinge met ander tekste in die oeuvre aandui , word gevolg. Hierdeur word aangetoon hoe die betekenis en die be-tekenisprosesse van die tekste onderling, en die bundel as 'n geheel, op transtekstuele samehang berus. In hierdie leesproses word nagegaan hoe, deur middel van die ontginning van die tekstuele elemente, 'n Boplaas-kode in die narratiewe proses tot stand kom. Hierdie Boplaas-kode beteken 'n Boplaas-ruimte asook 'n Boplaas-etos. Paternalisme, feodalisme en rassisme word as belangrike aspekte van hierdie bestel geenkodeer en die tekste toon aan dat sosiale versplintering endemies aan die betrokke orde is en slegs deur impulse van buite verhaas word. In die bundel-analise word aangetoon hoe, as gevolg van die organisasie van die vertel stof, hierdie bundel bevraagtekenend ten opsigte van die feodale status quo staan. As gevolg hiervan is daar dus alreeds in die vroegste prosa van Boerneef 'n demitologisering van die "vroegre boere- paradijs" ingebed. Die ondersoek toon egter ook aan dat die Boplaas-tekste by die sosiopolitiko- ekonomiese dimensies verby óók die eksistensële aspekte van die mens se betstaan be-teken.
- Full Text:
- Date Issued: 1989
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