A sea is brewing
- Authors: Mama, Sibongakonke
- Date: 2022-10-14
- Subjects: Creative writing (Higher education) South Africa , Xhosa poetry 21st century , South African poetry (English) 21st century , Psychic trauma in literature , Women in literature , Diaries -- Authorship , Books Reviews
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/406281 , vital:70255
- Description: My thesis is a collection of poems that draws on the complexity of not belonging in places, with people, or within families. I engage my own alienation as well as that of my parents, black people generally, and women in particular. I take inspiration from Uruguayan poet Fabián Severo’s autobiographical long poem, Night in the North, which chronicles the poet’s experience of growing up in linguistic and cultural borderlands. I am also influenced by Chilean poet Carmen García’s ability to move between the concrete and the abstract in translations of her poems from the collection Gotas sobre loza fría. As much as my poems traverse a metaphysical space, they are also set in concrete places – Tutura, Gcuwa, Johannesburg, and Cape Town. Like Chilean artist Cecilia Vicuña’s Spit Temple, I move between the physical and spiritual realms for a better understanding of my estrangement. I also draw on South African poet Mangaliso Buzani’s book, a naked bone, for its fluid combination of line and prose poetry. I write in isiXhosa and English as a reflection of my mixed cultural and linguistic existence. I seek to harness rhythm and harmony, as well as the quiet, between words. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-10-14
- Authors: Mama, Sibongakonke
- Date: 2022-10-14
- Subjects: Creative writing (Higher education) South Africa , Xhosa poetry 21st century , South African poetry (English) 21st century , Psychic trauma in literature , Women in literature , Diaries -- Authorship , Books Reviews
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/406281 , vital:70255
- Description: My thesis is a collection of poems that draws on the complexity of not belonging in places, with people, or within families. I engage my own alienation as well as that of my parents, black people generally, and women in particular. I take inspiration from Uruguayan poet Fabián Severo’s autobiographical long poem, Night in the North, which chronicles the poet’s experience of growing up in linguistic and cultural borderlands. I am also influenced by Chilean poet Carmen García’s ability to move between the concrete and the abstract in translations of her poems from the collection Gotas sobre loza fría. As much as my poems traverse a metaphysical space, they are also set in concrete places – Tutura, Gcuwa, Johannesburg, and Cape Town. Like Chilean artist Cecilia Vicuña’s Spit Temple, I move between the physical and spiritual realms for a better understanding of my estrangement. I also draw on South African poet Mangaliso Buzani’s book, a naked bone, for its fluid combination of line and prose poetry. I write in isiXhosa and English as a reflection of my mixed cultural and linguistic existence. I seek to harness rhythm and harmony, as well as the quiet, between words. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-10-14
Chaos!
- Ngwenya, Thembalethu Sabrina
- Authors: Ngwenya, Thembalethu Sabrina
- Date: 2022-10-14
- Subjects: Creative writing (Higher education) South Africa , Diaries -- Authorship , Books Reviews , South African prose literature (English) 21st century , South African fiction (English) 21st century
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/406298 , vital:70256
- Description: Chaos! is a combination of short prose forms in fragments that tackles difficult topics such as troubled marriages, child molestation, rape, infidelity and abuse in every way, whether it is mental, emotional or physical. The stories contain a lot of horrific and violent acts that, often times in this day and age, happen behind closed doors or sometimes even openly, yet not a lot of people are ready to talk about these topics. In my thesis, I go into the minds of those that are abusive and those that are on the receiving end of abuse. In doing so, I aim to explore all the dynamics of abuse. Abusers, as I have portrayed in my thesis, tend to have a deranged sense of reasoning in performing abusive acts and one thing that is important to note is that, more than likely, in their own heads and according to their own reasoning, the behaviour that they act on is very much rational and reasonable. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-10-14
- Authors: Ngwenya, Thembalethu Sabrina
- Date: 2022-10-14
- Subjects: Creative writing (Higher education) South Africa , Diaries -- Authorship , Books Reviews , South African prose literature (English) 21st century , South African fiction (English) 21st century
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/406298 , vital:70256
- Description: Chaos! is a combination of short prose forms in fragments that tackles difficult topics such as troubled marriages, child molestation, rape, infidelity and abuse in every way, whether it is mental, emotional or physical. The stories contain a lot of horrific and violent acts that, often times in this day and age, happen behind closed doors or sometimes even openly, yet not a lot of people are ready to talk about these topics. In my thesis, I go into the minds of those that are abusive and those that are on the receiving end of abuse. In doing so, I aim to explore all the dynamics of abuse. Abusers, as I have portrayed in my thesis, tend to have a deranged sense of reasoning in performing abusive acts and one thing that is important to note is that, more than likely, in their own heads and according to their own reasoning, the behaviour that they act on is very much rational and reasonable. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-10-14
Fractured flowers
- Authors: Cunningham, Cornelia
- Date: 2022-10-14
- Subjects: Creative writing (Higher education) South Africa , Diaries -- Authorship , South African essays (English) 21st century , Books Reviews , South African fiction (English) 21st century
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/406226 , vital:70250
- Description: This portfolio contains extracts of my reflective journals that I wrote throughout the course of the year. My poetics essay, four book reviews, community engagement report and my reflection regarding the reader report is also attached. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-10-14
- Authors: Cunningham, Cornelia
- Date: 2022-10-14
- Subjects: Creative writing (Higher education) South Africa , Diaries -- Authorship , South African essays (English) 21st century , Books Reviews , South African fiction (English) 21st century
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/406226 , vital:70250
- Description: This portfolio contains extracts of my reflective journals that I wrote throughout the course of the year. My poetics essay, four book reviews, community engagement report and my reflection regarding the reader report is also attached. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-10-14
Poems caught in dreams
- Jafta, Nthabiseng Rose JahRose
- Authors: Jafta, Nthabiseng Rose JahRose
- Date: 2022-10-14
- Subjects: Creative writing (Higher education) South Africa , South African poetry (English) 21st century
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/406249 , vital:70252
- Description: My thesis is a collection of Lyrical and Prose Poetry. I am strongly influenced by Marina Tsvetaeva’s observation that “The condition of creation is a condition of dreaming.” As a writer I want to contribute to human knowledge by drawing from a wide literary ancestry, participating in a community of distinct voices and styles to capture and preserve the language of dreams. I fuse inherited knowledge, visions, dreams, my own experiences and what I have discovered through listening to music, reading and my own experiments in exploring poetry in dreams, thoughts and lived experiences. I am inspired by Sindiwe Magona, how she chose to express her spirituality and personal narratives into her work, and Aimé Césaire’s vision “The ground of poetic knowledge, [is] an astonishing mobilization of all human and cosmic forces.” I particularly enjoy intense forms of expression that hold substance and provoke one to elevate in knowledge and in writing. Exploring these combination of forces from these writers affords me an opportunity to write my dreams as reality. Exploring the characters, the different scenes, symbols and colours as poems flashing super/naturally yet leave one with fathomable felt, though sometimes hazy interpretations. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-10-14
- Authors: Jafta, Nthabiseng Rose JahRose
- Date: 2022-10-14
- Subjects: Creative writing (Higher education) South Africa , South African poetry (English) 21st century
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/406249 , vital:70252
- Description: My thesis is a collection of Lyrical and Prose Poetry. I am strongly influenced by Marina Tsvetaeva’s observation that “The condition of creation is a condition of dreaming.” As a writer I want to contribute to human knowledge by drawing from a wide literary ancestry, participating in a community of distinct voices and styles to capture and preserve the language of dreams. I fuse inherited knowledge, visions, dreams, my own experiences and what I have discovered through listening to music, reading and my own experiments in exploring poetry in dreams, thoughts and lived experiences. I am inspired by Sindiwe Magona, how she chose to express her spirituality and personal narratives into her work, and Aimé Césaire’s vision “The ground of poetic knowledge, [is] an astonishing mobilization of all human and cosmic forces.” I particularly enjoy intense forms of expression that hold substance and provoke one to elevate in knowledge and in writing. Exploring these combination of forces from these writers affords me an opportunity to write my dreams as reality. Exploring the characters, the different scenes, symbols and colours as poems flashing super/naturally yet leave one with fathomable felt, though sometimes hazy interpretations. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-10-14
Portraits
- Authors: Fredericks, Gaireyah
- Date: 2022-10-14
- Subjects: Kaaps , Creative writing (Higher education) South Africa , Diaries -- Authorship , Books Reviews , Afrikaans essays 21st century , Short stories, Afrikaans 21st century
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/406238 , vital:70251
- Description: Die portfolio bestaan yt reflections op my writing process during die course, my reading, my poetics essay en vier boek resensies. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-10-14
- Authors: Fredericks, Gaireyah
- Date: 2022-10-14
- Subjects: Kaaps , Creative writing (Higher education) South Africa , Diaries -- Authorship , Books Reviews , Afrikaans essays 21st century , Short stories, Afrikaans 21st century
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/406238 , vital:70251
- Description: Die portfolio bestaan yt reflections op my writing process during die course, my reading, my poetics essay en vier boek resensies. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-10-14
Alien crosstalk
- Stuart-Watson, Andrew Joseph
- Authors: Stuart-Watson, Andrew Joseph
- Date: 2022-04-07
- Subjects: Creative writing (Higher education) South Africa , Diaries -- Authorship , Short stories, South African (English) 21st century , South African essays (English) 21st century , American fiction History and criticism
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/294515 , vital:57228
- Description: Alien Crosstalk , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-04-07
- Authors: Stuart-Watson, Andrew Joseph
- Date: 2022-04-07
- Subjects: Creative writing (Higher education) South Africa , Diaries -- Authorship , Short stories, South African (English) 21st century , South African essays (English) 21st century , American fiction History and criticism
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/294515 , vital:57228
- Description: Alien Crosstalk , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-04-07
Along the river that flowed south
- Authors: Mohlomi, Teboho Samson
- Date: 2022-04-07
- Subjects: Uncatalogued
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/234195 , vital:50171
- Description: Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-04-07
- Authors: Mohlomi, Teboho Samson
- Date: 2022-04-07
- Subjects: Uncatalogued
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/234195 , vital:50171
- Description: Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-04-07
Hiding no scars
- Authors: Mhlongo, Sanele
- Date: 2022-04-07
- Subjects: Creative writing (Higher education) South Africa , South African poetry (English) 21st century , Interpersonal relations in literature , Diaries -- Authorship , South African essays (English) 21st century , Russian poetry 20th century History and criticism , South African fiction (English) 21st century History and criticism , Greek poetry History and criticism , German poetry 20th century History and criticism
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/294311 , vital:57190
- Description: My thesis is a collection of free-verse narrative and prose poetry focusing on rural life and people, as well as my personal relationships. Poetry through its play with language has the ability to say things with immediacy and allows unnoticed things to acquire relevance. It gives me a framework within which to express difficult themes such as family relationships, death, solitude, and poverty. In writing these poems I have drawn on the work of Constantine P. Cavafy, particularly the poems ‘Ithaka’, ‘The City’ and ‘As Much As You Can’ which showcase his consistently simple narrative style that covers profound subjects. I have also been influenced by Paul Celan’s poetry in his collection Breathturn Into Timestead where poems such as ‘Corona’, ‘In praise of remoteness’ and ‘Twelve Years’ demonstrate how poetry can have pace through tightly controlled yet experimental structure. I have also drawn on Anna Akhmatova’s symbolic poetry, specifically the poems ‘Now the pillow’s’, ‘He loved three things, alive’ and ‘Prologue’ from the selection Anna Akhmatova: Selected Poems which has its intention the re-creation of the past in the present. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-04-07
- Authors: Mhlongo, Sanele
- Date: 2022-04-07
- Subjects: Creative writing (Higher education) South Africa , South African poetry (English) 21st century , Interpersonal relations in literature , Diaries -- Authorship , South African essays (English) 21st century , Russian poetry 20th century History and criticism , South African fiction (English) 21st century History and criticism , Greek poetry History and criticism , German poetry 20th century History and criticism
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/294311 , vital:57190
- Description: My thesis is a collection of free-verse narrative and prose poetry focusing on rural life and people, as well as my personal relationships. Poetry through its play with language has the ability to say things with immediacy and allows unnoticed things to acquire relevance. It gives me a framework within which to express difficult themes such as family relationships, death, solitude, and poverty. In writing these poems I have drawn on the work of Constantine P. Cavafy, particularly the poems ‘Ithaka’, ‘The City’ and ‘As Much As You Can’ which showcase his consistently simple narrative style that covers profound subjects. I have also been influenced by Paul Celan’s poetry in his collection Breathturn Into Timestead where poems such as ‘Corona’, ‘In praise of remoteness’ and ‘Twelve Years’ demonstrate how poetry can have pace through tightly controlled yet experimental structure. I have also drawn on Anna Akhmatova’s symbolic poetry, specifically the poems ‘Now the pillow’s’, ‘He loved three things, alive’ and ‘Prologue’ from the selection Anna Akhmatova: Selected Poems which has its intention the re-creation of the past in the present. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-04-07
Praying mantis
- Authors: Kenene, Thobeka
- Date: 2022-04-07
- Subjects: Creative writing (Higher education) South Africa , Diaries -- Authorship , South African fiction (English) 21st century , South African essays (English) 21st century , Portuguese fiction 20th century History and criticism , Russian fiction 20th century History and criticism , Zimbabwean fiction (English) 20th century History and criticism , American fiction 20th century History and criticism
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/292726 , vital:57010
- Description: (Prologue) I could only see in black and white as if I had travelled through time. I was the star of the medieval people who waited on me. The city was Johannesburg where strange faces called me a traitor because I was an educated black person. I hid between the skyscrapers and ran into a mirror image of myself as a man. “I write this book,” he said to his readers, “To invoke a yearning in our youth to awaken from slumber. To set examples for them to desist from characters like Velesazi and Nongendi, and imitate Nomsa and Themba. And also, to contribute to Xhosa literature.” He signed off by calling himself our servant. These are the words from the note my great-grandfather left me. We walked together across a barren field and past a graveyard. I was feeling tired and lost; I wanted to get home as fast as possible. We quickened our step and entered a church site. Inside the church were all my close relatives. I saw myself on stage looking down at them, and when I opened my mouth to sing, they began laughing at me. I imagined him in his 1917 suit, as a writer, penning down his first novel that is dedicated to his mother. His round cheeks enveloped in a haze of candle light. He visited my dream in 2012 and in the dream he asked me, “Do you see?” I said, “Yes, I see.” My great-grandfather hummed a song from his belly. I inhaled deeply into my belly and then exhaled a sound. Together we hummed this song that made everyone fall silent and listen. In the dream I could feel my lungs expanding and deflating along to the rhythm of the song. As my great-grandfather and I sang it, the night lamps shone brighter. I had become my great-grandfather, wearing his suit and black leather shoes. His friends were my friends. They turned and asked me what my clan name was. When I told them, they whispered something among themselves. One of them said to me, “Unogcwabevu.” I saw a white unknown woman who was afraid of me. I told her it is going to be okay, and that I would not harm her. But the colour of my skin frightened her. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-04-07
- Authors: Kenene, Thobeka
- Date: 2022-04-07
- Subjects: Creative writing (Higher education) South Africa , Diaries -- Authorship , South African fiction (English) 21st century , South African essays (English) 21st century , Portuguese fiction 20th century History and criticism , Russian fiction 20th century History and criticism , Zimbabwean fiction (English) 20th century History and criticism , American fiction 20th century History and criticism
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/292726 , vital:57010
- Description: (Prologue) I could only see in black and white as if I had travelled through time. I was the star of the medieval people who waited on me. The city was Johannesburg where strange faces called me a traitor because I was an educated black person. I hid between the skyscrapers and ran into a mirror image of myself as a man. “I write this book,” he said to his readers, “To invoke a yearning in our youth to awaken from slumber. To set examples for them to desist from characters like Velesazi and Nongendi, and imitate Nomsa and Themba. And also, to contribute to Xhosa literature.” He signed off by calling himself our servant. These are the words from the note my great-grandfather left me. We walked together across a barren field and past a graveyard. I was feeling tired and lost; I wanted to get home as fast as possible. We quickened our step and entered a church site. Inside the church were all my close relatives. I saw myself on stage looking down at them, and when I opened my mouth to sing, they began laughing at me. I imagined him in his 1917 suit, as a writer, penning down his first novel that is dedicated to his mother. His round cheeks enveloped in a haze of candle light. He visited my dream in 2012 and in the dream he asked me, “Do you see?” I said, “Yes, I see.” My great-grandfather hummed a song from his belly. I inhaled deeply into my belly and then exhaled a sound. Together we hummed this song that made everyone fall silent and listen. In the dream I could feel my lungs expanding and deflating along to the rhythm of the song. As my great-grandfather and I sang it, the night lamps shone brighter. I had become my great-grandfather, wearing his suit and black leather shoes. His friends were my friends. They turned and asked me what my clan name was. When I told them, they whispered something among themselves. One of them said to me, “Unogcwabevu.” I saw a white unknown woman who was afraid of me. I told her it is going to be okay, and that I would not harm her. But the colour of my skin frightened her. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-04-07
Sexual socialisation: young adult women storying how sexual activities were discussed in South African cultural contexts
- Authors: Ludidi, Zizipho
- Date: 2022-04-07
- Subjects: Socialization South Africa , Sex Social aspects South Africa , Young women Socialization South Africa , Young women Sexual behavior South Africa , Culture , Memory , Narrative inquiry (Research method)
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/292737 , vital:57011
- Description: Epidemics such as HIV/AIDS, unplanned pregnancy, gender-based violence and homophobia, in South Africa, have focused research on how young people learn about sex. This research has often focused on young girls from risk-saturated areas, and specific agents of socialisation, where they might learn about sex, such as parents, life orientation at schools, peers, media, and traditional cultural approaches. Using a narrative theoretical framework, through memory work, this study explored how black young adult women friends – who were university students – experienced forms of sexual socialisation, through various communication in South African cultural contexts. Findings from the thematic narrative analysis that was conducted demonstrated that sexual socialisation is a complex life-long process. This takes place through a collision of contradictory messages, from different agents of socialisation, in different cultural contexts. Themes were identified and organised to tell an overall sexual socialisation story that progressed through time, moving from a stage of perceived innocent oblivion, mixed messages in primary and high school, “liberal” university stories and the current stage of reauthoring stories. , Thesis (MA) -- Faculty of Humanities, Psychology, 2022
- Full Text:
- Date Issued: 2022-04-07
- Authors: Ludidi, Zizipho
- Date: 2022-04-07
- Subjects: Socialization South Africa , Sex Social aspects South Africa , Young women Socialization South Africa , Young women Sexual behavior South Africa , Culture , Memory , Narrative inquiry (Research method)
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/292737 , vital:57011
- Description: Epidemics such as HIV/AIDS, unplanned pregnancy, gender-based violence and homophobia, in South Africa, have focused research on how young people learn about sex. This research has often focused on young girls from risk-saturated areas, and specific agents of socialisation, where they might learn about sex, such as parents, life orientation at schools, peers, media, and traditional cultural approaches. Using a narrative theoretical framework, through memory work, this study explored how black young adult women friends – who were university students – experienced forms of sexual socialisation, through various communication in South African cultural contexts. Findings from the thematic narrative analysis that was conducted demonstrated that sexual socialisation is a complex life-long process. This takes place through a collision of contradictory messages, from different agents of socialisation, in different cultural contexts. Themes were identified and organised to tell an overall sexual socialisation story that progressed through time, moving from a stage of perceived innocent oblivion, mixed messages in primary and high school, “liberal” university stories and the current stage of reauthoring stories. , Thesis (MA) -- Faculty of Humanities, Psychology, 2022
- Full Text:
- Date Issued: 2022-04-07
Comparison of a novel HPLC method and conventional protein assays for the quantitation of insulin aspart in Novorapid®
- Authors: Dickson, Courtney Rae
- Date: 2022-04-06
- Subjects: Uncatalogued
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/290704 , vital:56776
- Description: Thesis (MSc) -- Faculty of Pharmacy, Pharmacy, 2022
- Full Text:
- Date Issued: 2022-04-06
- Authors: Dickson, Courtney Rae
- Date: 2022-04-06
- Subjects: Uncatalogued
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/290704 , vital:56776
- Description: Thesis (MSc) -- Faculty of Pharmacy, Pharmacy, 2022
- Full Text:
- Date Issued: 2022-04-06
Fabrication and characterization of ciprofloxacin loaded niosomes for transtympanic delivery
- Authors: Mhlanga, Asavela
- Date: 2022-04-06
- Subjects: Drug delivery systems , Liposomes , Ciprofloxacin , Quinolone antibacterial agents , Drug carriers (Pharmacy) , Drug stability , Lamellarity , Niosomes
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/290715 , vital:56777
- Description: Ciprofloxacin (CPH) is a broad-spectrum antibiotic used to treat bone, joint, and skin infections. It is commercially available as an extended-release tablet and as a cream dosage form. CPH is a bactericidal active pharmaceutical ingredient (API) of the fluoroquinolone drug class. It inhibits deoxyribonucleic acid (DNA) replication by inhibiting bacterial DNA topoisomerase and DNA gyrase enzymes. Common adverse effects include nausea, vomiting, unusual fatigue, pale skin, and may increase the risk of tendinitis, which could be a major concern. CPH is, according to the Biopharmaceutics Classification System (BCS), classified as a BCS class IV drug exhibiting low oral bioavailability, low solubility, and intestinal permeability. CPH was chosen as a good candidate for the study because of its stability in solutions, its low molecular weight (331.4 g/mol), and its moderate lipophilicity (log P = 0.28) [16]. The use of conventional ear drops in the ear is effective, avoids hepatic first metabolism and extensive protein binding and may reduce adverse effects as a low dose may be used to achieve a therapeutic effect. However, conventional ear drops and oral antibiotics have a long onset of action and have to be taken/applied in short intervals. For convenience and assurance of a long residence time in the ear, CPH may be delivered by using a niosomal formulation, a liquid at room temperature, to allow administration into the ear without the need to constantly apply the ear drops for long periods of time. A simple, rapid, precise, accurate, reproducible, and specific reversed-phase high-performance liquid chromatography (RP-HPLC) method using ultraviolet (UV) detection for the quantitation of CPH was developed and optimized using a central composite design (CCD). The method was validated using International Conference on Harmonisation (ICH) guidelines and was found to be linear, precise, accurate, and specific for the analysis of CPH. Since the method is specific, it was used to quantify CPH in commercial and experimental formulations and monitor CPH released during in-vitro release testing. The compatibility of CPH and potential excipients was investigated during preformulation studies using Fourier transform infrared spectroscopy (FT-IR) and differential scanning calorimetry (DSC) to identify and select suitable excipients for use during formulation development activities. No apparent interactions were evident between CPH, and the excipients tested. The probe sonication method was used to manufacture CPH loaded niosomes using different surfactants/surfactant combinations, and a combination of Tween® 80: sodium lauryl sulfate (SLS) was found to be the best composition in terms of both entrapment efficiency and Zeta potential. The limits for the independent input variables used for the manufacture included amplitude, sonication time, and amount of cholesterol were determined. Design of experiments (DOE) was used to design the study. The input variables investigated included amplitude, amount of cholesterol, and sonication time. The output or responses monitored included Zeta potential, vesicle size, polydispersity index (PDI), and entrapment efficiency. Non-ionic surfactant systems are predominantly stabilized by steric stabilization, and there is only a minor electrostatic element from adsorbed hydroxyl ions. With the inclusion of SLS it is to be expected that Zeta potential will be a contributing factor. DOE using Box-Behnken design (BBD) and response surface methodology (RSM) in addition to Artificial Neural Networks (ANN) were used for the optimization of the formulation. The optimized formulation had a composition of 1 g cholesterol, 1 g of Tween® 80, 1 g of SLS and was prepared at an amplitude of 11.294 % with a sonication time of 3.304 minutes. The formulation exhibited zero-order release kinetics and had an average pH of 7.45. The formulation was stored at 4 ℃ and 25 ℃ and was assessed for vesicle size, entrapment efficiency, Zeta potential, colour, lamellarity, and PDI every 7 days for 4 weeks. The lead formulation stored at 4 ℃ was more stable than the formulation at 25 ℃ in terms of entrapment efficiency, PDI and vesicle size during the 4-week period. CPH loaded niosomes for transtympanic delivery in the treatment of otitis media were developed and optimized. The technology exhibits sustained release of CPH and has the potential for further development and optimization. , Thesis (MSc) -- Faculty of Pharmacy, Pharmacy, 2022
- Full Text:
- Date Issued: 2022-04-06
- Authors: Mhlanga, Asavela
- Date: 2022-04-06
- Subjects: Drug delivery systems , Liposomes , Ciprofloxacin , Quinolone antibacterial agents , Drug carriers (Pharmacy) , Drug stability , Lamellarity , Niosomes
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/290715 , vital:56777
- Description: Ciprofloxacin (CPH) is a broad-spectrum antibiotic used to treat bone, joint, and skin infections. It is commercially available as an extended-release tablet and as a cream dosage form. CPH is a bactericidal active pharmaceutical ingredient (API) of the fluoroquinolone drug class. It inhibits deoxyribonucleic acid (DNA) replication by inhibiting bacterial DNA topoisomerase and DNA gyrase enzymes. Common adverse effects include nausea, vomiting, unusual fatigue, pale skin, and may increase the risk of tendinitis, which could be a major concern. CPH is, according to the Biopharmaceutics Classification System (BCS), classified as a BCS class IV drug exhibiting low oral bioavailability, low solubility, and intestinal permeability. CPH was chosen as a good candidate for the study because of its stability in solutions, its low molecular weight (331.4 g/mol), and its moderate lipophilicity (log P = 0.28) [16]. The use of conventional ear drops in the ear is effective, avoids hepatic first metabolism and extensive protein binding and may reduce adverse effects as a low dose may be used to achieve a therapeutic effect. However, conventional ear drops and oral antibiotics have a long onset of action and have to be taken/applied in short intervals. For convenience and assurance of a long residence time in the ear, CPH may be delivered by using a niosomal formulation, a liquid at room temperature, to allow administration into the ear without the need to constantly apply the ear drops for long periods of time. A simple, rapid, precise, accurate, reproducible, and specific reversed-phase high-performance liquid chromatography (RP-HPLC) method using ultraviolet (UV) detection for the quantitation of CPH was developed and optimized using a central composite design (CCD). The method was validated using International Conference on Harmonisation (ICH) guidelines and was found to be linear, precise, accurate, and specific for the analysis of CPH. Since the method is specific, it was used to quantify CPH in commercial and experimental formulations and monitor CPH released during in-vitro release testing. The compatibility of CPH and potential excipients was investigated during preformulation studies using Fourier transform infrared spectroscopy (FT-IR) and differential scanning calorimetry (DSC) to identify and select suitable excipients for use during formulation development activities. No apparent interactions were evident between CPH, and the excipients tested. The probe sonication method was used to manufacture CPH loaded niosomes using different surfactants/surfactant combinations, and a combination of Tween® 80: sodium lauryl sulfate (SLS) was found to be the best composition in terms of both entrapment efficiency and Zeta potential. The limits for the independent input variables used for the manufacture included amplitude, sonication time, and amount of cholesterol were determined. Design of experiments (DOE) was used to design the study. The input variables investigated included amplitude, amount of cholesterol, and sonication time. The output or responses monitored included Zeta potential, vesicle size, polydispersity index (PDI), and entrapment efficiency. Non-ionic surfactant systems are predominantly stabilized by steric stabilization, and there is only a minor electrostatic element from adsorbed hydroxyl ions. With the inclusion of SLS it is to be expected that Zeta potential will be a contributing factor. DOE using Box-Behnken design (BBD) and response surface methodology (RSM) in addition to Artificial Neural Networks (ANN) were used for the optimization of the formulation. The optimized formulation had a composition of 1 g cholesterol, 1 g of Tween® 80, 1 g of SLS and was prepared at an amplitude of 11.294 % with a sonication time of 3.304 minutes. The formulation exhibited zero-order release kinetics and had an average pH of 7.45. The formulation was stored at 4 ℃ and 25 ℃ and was assessed for vesicle size, entrapment efficiency, Zeta potential, colour, lamellarity, and PDI every 7 days for 4 weeks. The lead formulation stored at 4 ℃ was more stable than the formulation at 25 ℃ in terms of entrapment efficiency, PDI and vesicle size during the 4-week period. CPH loaded niosomes for transtympanic delivery in the treatment of otitis media were developed and optimized. The technology exhibits sustained release of CPH and has the potential for further development and optimization. , Thesis (MSc) -- Faculty of Pharmacy, Pharmacy, 2022
- Full Text:
- Date Issued: 2022-04-06
Integrating blockchain and microgrid technology to enable peer-to-peer energy trading: a business process model
- Authors: Higgs, James
- Date: 2022-04-06
- Subjects: Blockchains (Databases) , Peer-to-peer architecture (Computer networks) , Electric power-plants Decentralization South Africa , Microgrids (Smart power grids) South Africa , Energy trading , Business process model
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/284559 , vital:56074
- Description: Traditional centralised energy systems are coming under increasing pressure because of decarbonisation, decentralisation, and digitisation. A lack of energy security and the inability to manage bi-directional electricity flows constitute two of the biggest challenges faced by centralised systems. Furthermore, in South Africa, the country’s energy system remains monopolised with one large utility satisfying most of the country’s electricity demand. This study is motivated by the need to address energy security within such a monopolised market. To redress the problems highlighted above, this study explores how blockchain and microgrid technology can be integrated to enable decentralised energy production and trading in South Africa. As such, this study develops a fully integrated blockchain-based microgrid energy trading system model. The functional requirements of the system are presented in the form of a business process model. Amongst other benefits, an active blockchain-based microgrid energy trading system provides a means to bolster energy security for the systems’ users. A unique aspect of this study’s approach to energy trading is the utilisation of blockchain’s native tokenizing capabilities. Prosumer energy tokens are minted to create a digital currency for local peer-to-peer energy exchange. A commons-rule based approach is adopted for governing energy resources. As such, this study demonstrates that commons-based solutions provide a feasible alternative to market and profit driven trading for organizing local energy exchange. The primary deliverable of this study satisfies the request of various blockchain researchers for blockchain research to focus on holistic conceptualisations, rather than on the minutiae of blockchain technicalities. Eight core functional requirements of a blockchain energy trading system were identified prior to the construction of the process model. The functional requirements were elicited during a scoping review as a part of the secondary data collection process. Expert review was utilised to verify the functional requirements of the blockchain energy trading system. Once the experts were identified, each expert completed a questionnaire with the intention to verify the requirements. The above process constituted the expert review process for the study. Additionally, the syntactic correctness of the business process model was verified by a business process modelling expert. Weber’s Theory of Evaluation constitutes the theoretical underpinning for the evaluation of the system parts. This study contributes the first publicly accessible business process models of a blockchain-based microgrid energy trading system. This study seeks to advance the discussion of a more integrative and cross disciplinary approach concerning blockchain research, particularly as it pertains to microgrid energy trading. , Thesis (MCom) -- Faculty of Commerce, Department of Information Systems, 2022
- Full Text:
- Date Issued: 2022-04-06
- Authors: Higgs, James
- Date: 2022-04-06
- Subjects: Blockchains (Databases) , Peer-to-peer architecture (Computer networks) , Electric power-plants Decentralization South Africa , Microgrids (Smart power grids) South Africa , Energy trading , Business process model
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/284559 , vital:56074
- Description: Traditional centralised energy systems are coming under increasing pressure because of decarbonisation, decentralisation, and digitisation. A lack of energy security and the inability to manage bi-directional electricity flows constitute two of the biggest challenges faced by centralised systems. Furthermore, in South Africa, the country’s energy system remains monopolised with one large utility satisfying most of the country’s electricity demand. This study is motivated by the need to address energy security within such a monopolised market. To redress the problems highlighted above, this study explores how blockchain and microgrid technology can be integrated to enable decentralised energy production and trading in South Africa. As such, this study develops a fully integrated blockchain-based microgrid energy trading system model. The functional requirements of the system are presented in the form of a business process model. Amongst other benefits, an active blockchain-based microgrid energy trading system provides a means to bolster energy security for the systems’ users. A unique aspect of this study’s approach to energy trading is the utilisation of blockchain’s native tokenizing capabilities. Prosumer energy tokens are minted to create a digital currency for local peer-to-peer energy exchange. A commons-rule based approach is adopted for governing energy resources. As such, this study demonstrates that commons-based solutions provide a feasible alternative to market and profit driven trading for organizing local energy exchange. The primary deliverable of this study satisfies the request of various blockchain researchers for blockchain research to focus on holistic conceptualisations, rather than on the minutiae of blockchain technicalities. Eight core functional requirements of a blockchain energy trading system were identified prior to the construction of the process model. The functional requirements were elicited during a scoping review as a part of the secondary data collection process. Expert review was utilised to verify the functional requirements of the blockchain energy trading system. Once the experts were identified, each expert completed a questionnaire with the intention to verify the requirements. The above process constituted the expert review process for the study. Additionally, the syntactic correctness of the business process model was verified by a business process modelling expert. Weber’s Theory of Evaluation constitutes the theoretical underpinning for the evaluation of the system parts. This study contributes the first publicly accessible business process models of a blockchain-based microgrid energy trading system. This study seeks to advance the discussion of a more integrative and cross disciplinary approach concerning blockchain research, particularly as it pertains to microgrid energy trading. , Thesis (MCom) -- Faculty of Commerce, Department of Information Systems, 2022
- Full Text:
- Date Issued: 2022-04-06
Mediating transition to household electricity conservation through co-designing in Makhanda, South Africa
- Authors: Mutumbi, Uzziah
- Date: 2022-04-06
- Subjects: Households Energy consumption South Africa Makhanda , Renewable energy sources South Africa , Consumer behavior South Africa Makhanda , Energy conservation South Africa Makhanda Citizen participation , Low-income consumers South Africa Makhanda
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/291262 , vital:56838
- Description: Households consume up to 20% of total global electricity consumption, hence they are important role players in efforts for promoting sustainable consumption. Research on electricity-use behaviour and effectiveness of interventions is important for informing intervention strategies. However, relative to developed countries, research on this subject is lacking in developing countries, where electricity access is limited, and a substantial proportion of households are energy poor. The main goal of this study was to examine reported electricity-use behaviour and the effects of co-designed interventions on household electricity consumption in low-income households in Makhanda, South Africa, using a field-based experiment. Findings from self-reported electricity-use practices showed mixed results, with households reporting both good electricity-use behaviour (e.g., cooling down hot food before refrigeration) and wasteful actions (e.g., leaving appliances on standby). Results showed that electricity-use behaviour was influenced by socio-psychological values including universalism, benevolence, hedonism, and power. Over the intervention period, households exposed to co-designed electricity-saving interventions showed mean electricity savings of about 5.5%, while households in the Partial Treatment and Control group showed increased electricity consumption. Socio-demographic factors such as age and psychological factors (involvement and perceived behavioural control) were very important determinants of household consumption. Broadly, the findings empirically validate the impact of collective problem formulation and co-designing interventions in promoting sustainable actions. , Thesis (MSc) -- Faculty of Science, Environmental Science, 2022
- Full Text:
- Date Issued: 2022-04-06
- Authors: Mutumbi, Uzziah
- Date: 2022-04-06
- Subjects: Households Energy consumption South Africa Makhanda , Renewable energy sources South Africa , Consumer behavior South Africa Makhanda , Energy conservation South Africa Makhanda Citizen participation , Low-income consumers South Africa Makhanda
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/291262 , vital:56838
- Description: Households consume up to 20% of total global electricity consumption, hence they are important role players in efforts for promoting sustainable consumption. Research on electricity-use behaviour and effectiveness of interventions is important for informing intervention strategies. However, relative to developed countries, research on this subject is lacking in developing countries, where electricity access is limited, and a substantial proportion of households are energy poor. The main goal of this study was to examine reported electricity-use behaviour and the effects of co-designed interventions on household electricity consumption in low-income households in Makhanda, South Africa, using a field-based experiment. Findings from self-reported electricity-use practices showed mixed results, with households reporting both good electricity-use behaviour (e.g., cooling down hot food before refrigeration) and wasteful actions (e.g., leaving appliances on standby). Results showed that electricity-use behaviour was influenced by socio-psychological values including universalism, benevolence, hedonism, and power. Over the intervention period, households exposed to co-designed electricity-saving interventions showed mean electricity savings of about 5.5%, while households in the Partial Treatment and Control group showed increased electricity consumption. Socio-demographic factors such as age and psychological factors (involvement and perceived behavioural control) were very important determinants of household consumption. Broadly, the findings empirically validate the impact of collective problem formulation and co-designing interventions in promoting sustainable actions. , Thesis (MSc) -- Faculty of Science, Environmental Science, 2022
- Full Text:
- Date Issued: 2022-04-06
Motives and barriers to the implementation of renewable energy sources in South African tertiary institutions
- Authors: Sibindi, Siyangiso
- Date: 2022-04-06
- Subjects: Renewable energy sources South Africa , Education, Higher South Africa , Education, Higher Environmental aspects South Africa , Environmental responsibility South Africa , Climate change mitigation South Africa , Sustainable development South Africa
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/284537 , vital:56072
- Description: Organisations face major challenges to address the exploitation of non-renewable resources and consider management considerations for dealing with climate change. Organisations have been pushed to play a part in their carbon footprints and in curbing climate change. Among these organisations are tertiary institutions that can greatly impact environmental sustainability and address carbon dioxide emissions by embarking on renewable energy technologies. Tertiary institutions play a major role in society by the provision of skilled labour and personnel that are equipped to deal with a range of advancements and challenges. The sustainability of these tertiary institutions has thus been called into question due to the impact they can bring to societies. This research thus aims to identify the motives and barriers to renewable energy adoption in tertiary education institutions. To do this, a literature review was conducted to identify possible motives and barriers to renewable energy adoption. These were then compiled into a questionnaire that was sent to respondents of three different institutions. Respondents were then requested to give feedback on each of the motives and barriers. The respondents were also asked general questions found in literature that addressed the adoption of renewable energy technologies in tertiary institutions. The data was collected using the designed questionnaires. The respondents were able to articulate their perceived barriers and motives to the implementation of renewable energy technologies in tertiary institutions. Data analysis was done using thematic analysis. The results showed that the barriers in the implementation of renewable energy technologies in tertiary institutions were: ‘Cost to Install’, ‘Transition Process’ and ‘Government Policies’. The motives on why educational institutions need to embark on renewable energy projects were found to be ‘Energy Independence’, ‘Cleaner Source of Energy’ and ‘Reduction in Carbon Emissions’. The cost of renewable energy technologies, the process of moving from the Eskom grid, and renewable energy policies that are ambiguous were some factors that were highlighted by respondents on why it is challenging to adopt renewable energies in tertiary institutions. On the other hand, the effects of load shedding currently being experienced in the country and the migration to cleaner sources of energy that cause less harm to the environment, are some of the drivers noted by respondents on why tertiary institutions need to embark on renewable energy technologies. More emphasis needs to be put by stakeholders on tertiary institutions to migrate to cleaner sources of energy, and policies need to be put in place in order to promote institutions to adopt these types of energies. Governments and other role-players need to be visible at all times in addressing energy challenges in tertiary institutions in the wake of the recent load-shedding concerns that have been crippling South Africa. , Thesis (MBA) -- Faculty of Commerce, Rhodes Business School, 2022
- Full Text:
- Date Issued: 2022-04-06
- Authors: Sibindi, Siyangiso
- Date: 2022-04-06
- Subjects: Renewable energy sources South Africa , Education, Higher South Africa , Education, Higher Environmental aspects South Africa , Environmental responsibility South Africa , Climate change mitigation South Africa , Sustainable development South Africa
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/284537 , vital:56072
- Description: Organisations face major challenges to address the exploitation of non-renewable resources and consider management considerations for dealing with climate change. Organisations have been pushed to play a part in their carbon footprints and in curbing climate change. Among these organisations are tertiary institutions that can greatly impact environmental sustainability and address carbon dioxide emissions by embarking on renewable energy technologies. Tertiary institutions play a major role in society by the provision of skilled labour and personnel that are equipped to deal with a range of advancements and challenges. The sustainability of these tertiary institutions has thus been called into question due to the impact they can bring to societies. This research thus aims to identify the motives and barriers to renewable energy adoption in tertiary education institutions. To do this, a literature review was conducted to identify possible motives and barriers to renewable energy adoption. These were then compiled into a questionnaire that was sent to respondents of three different institutions. Respondents were then requested to give feedback on each of the motives and barriers. The respondents were also asked general questions found in literature that addressed the adoption of renewable energy technologies in tertiary institutions. The data was collected using the designed questionnaires. The respondents were able to articulate their perceived barriers and motives to the implementation of renewable energy technologies in tertiary institutions. Data analysis was done using thematic analysis. The results showed that the barriers in the implementation of renewable energy technologies in tertiary institutions were: ‘Cost to Install’, ‘Transition Process’ and ‘Government Policies’. The motives on why educational institutions need to embark on renewable energy projects were found to be ‘Energy Independence’, ‘Cleaner Source of Energy’ and ‘Reduction in Carbon Emissions’. The cost of renewable energy technologies, the process of moving from the Eskom grid, and renewable energy policies that are ambiguous were some factors that were highlighted by respondents on why it is challenging to adopt renewable energies in tertiary institutions. On the other hand, the effects of load shedding currently being experienced in the country and the migration to cleaner sources of energy that cause less harm to the environment, are some of the drivers noted by respondents on why tertiary institutions need to embark on renewable energy technologies. More emphasis needs to be put by stakeholders on tertiary institutions to migrate to cleaner sources of energy, and policies need to be put in place in order to promote institutions to adopt these types of energies. Governments and other role-players need to be visible at all times in addressing energy challenges in tertiary institutions in the wake of the recent load-shedding concerns that have been crippling South Africa. , Thesis (MBA) -- Faculty of Commerce, Rhodes Business School, 2022
- Full Text:
- Date Issued: 2022-04-06
The host specificity and efficacy of Phenrica guerini (Bechyné) (Coleoptera: Chrysomelidae), a candidate biological control agent of Pereskia aculeata Miller (Cactaceae) in Australia
- Authors: Dixon, Elizabeth Anne
- Date: 2022-04-06
- Subjects: Chrysomelidae Australia , Pereskia Australia , Pereskia Biological control Australia , Invasive plants Biological control Australia , Insects as biological pest control agents Australia , Cactus Biological control Australia
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/290826 , vital:56789
- Description: Pereskia aculeata Miller (Cactaceae) is a primitive creeping cactus that originated from South America and has become an invasive alien plant in South Africa and Australia. Due to its vine-like growth form mechanical and chemical control are not feasible options for its control, therefore biological control is the best option for controlling this plant. Phenrica guerini (Bechyné) (Chrysomelidae) is a leaf-feeding flea beetle that has been released as a biological control agent against Pe. aculeata in South Africa and has been shown to be damaging at some sites in the country. In this thesis, further studies into the use of Ph. guerini as a biological control agent against Pe. aculeata were conducted to determine whether the beetle should be released as an agent against the target weed in Australia. The host range of a potential biological control agent is important to determine as only monophagous agents, or agents with suitably restricted host ranges, should be considered for release. Host specificity testing was conducted to determine if Ph. guerini was suitably specific for release in Australia. Phenrica guerini larvae only fed and partially developed on three out of 25 test plants, but failed to pupate on any plants besides Pe. aculeata. Adult beetles did not feed on any test plants and only oviposited on one test plant species. Phenrica guerini did not develop on any plant other than the target weed and is therefore suitably host specific for release in Australia. The efficacy of a potential agent is also important to consider as the release of an ineffective agent can reduce the success of a biological control programme. A laboratory based pre-release efficacy assessment was done to determine the impact that Ph. guerini could have on Pe. aculeata. There was a significant difference between the control plants and those with larvae, with an average of 72 (S.E. ± 12.33) less leaves on plants with feeding and the main stem of the plant being 11.1 cm (S.E. ± 7.17) shorter. Although there were no significant differences observed in the number of additional stems, and weights of the different plant parts, this was not a long term study and many of these differences would not have been observed in a short period. Based on the impact observed on the leaves and the main stem, and various field studies that have been done to assess the impact of Ph. guerini on Pe. aculeata in the field in South Africa, Ph. guerini appears to be a potentially damaging agent. As Pe. aculeata is still in its early stages of invasion in Australia the beetle has the potential to be damaging and reduce the invasion trajectory of the plant. This study showed that the beetle is suitably host specific and potentially damaging enough to be recommended for release as a biological control agent against Pe. aculeata in Australia. , Thesis (MSc) -- Faculty of Science, Zoology and Entomology, 2022
- Full Text:
- Date Issued: 2022-04-06
- Authors: Dixon, Elizabeth Anne
- Date: 2022-04-06
- Subjects: Chrysomelidae Australia , Pereskia Australia , Pereskia Biological control Australia , Invasive plants Biological control Australia , Insects as biological pest control agents Australia , Cactus Biological control Australia
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/290826 , vital:56789
- Description: Pereskia aculeata Miller (Cactaceae) is a primitive creeping cactus that originated from South America and has become an invasive alien plant in South Africa and Australia. Due to its vine-like growth form mechanical and chemical control are not feasible options for its control, therefore biological control is the best option for controlling this plant. Phenrica guerini (Bechyné) (Chrysomelidae) is a leaf-feeding flea beetle that has been released as a biological control agent against Pe. aculeata in South Africa and has been shown to be damaging at some sites in the country. In this thesis, further studies into the use of Ph. guerini as a biological control agent against Pe. aculeata were conducted to determine whether the beetle should be released as an agent against the target weed in Australia. The host range of a potential biological control agent is important to determine as only monophagous agents, or agents with suitably restricted host ranges, should be considered for release. Host specificity testing was conducted to determine if Ph. guerini was suitably specific for release in Australia. Phenrica guerini larvae only fed and partially developed on three out of 25 test plants, but failed to pupate on any plants besides Pe. aculeata. Adult beetles did not feed on any test plants and only oviposited on one test plant species. Phenrica guerini did not develop on any plant other than the target weed and is therefore suitably host specific for release in Australia. The efficacy of a potential agent is also important to consider as the release of an ineffective agent can reduce the success of a biological control programme. A laboratory based pre-release efficacy assessment was done to determine the impact that Ph. guerini could have on Pe. aculeata. There was a significant difference between the control plants and those with larvae, with an average of 72 (S.E. ± 12.33) less leaves on plants with feeding and the main stem of the plant being 11.1 cm (S.E. ± 7.17) shorter. Although there were no significant differences observed in the number of additional stems, and weights of the different plant parts, this was not a long term study and many of these differences would not have been observed in a short period. Based on the impact observed on the leaves and the main stem, and various field studies that have been done to assess the impact of Ph. guerini on Pe. aculeata in the field in South Africa, Ph. guerini appears to be a potentially damaging agent. As Pe. aculeata is still in its early stages of invasion in Australia the beetle has the potential to be damaging and reduce the invasion trajectory of the plant. This study showed that the beetle is suitably host specific and potentially damaging enough to be recommended for release as a biological control agent against Pe. aculeata in Australia. , Thesis (MSc) -- Faculty of Science, Zoology and Entomology, 2022
- Full Text:
- Date Issued: 2022-04-06
A contingency management framework to mitigate cybersecurity threats to electronic health records in the public health sector in South Africa
- Ngxabane, Mbulelo https://orcid.org/0000-0003-2942-2568
- Authors: Ngxabane, Mbulelo https://orcid.org/0000-0003-2942-2568
- Date: 2021-11
- Subjects: Health services administration--Information technology , Computer Security
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/23427 , vital:57730
- Description: Most developing countries in the African continent, including South Africa, seem to be lagging behind in research, policy development, and how to prevent cybersecurity threats. These findings are evident in the significant number of cyberattacks recorded in the Cost of Data Breach Study and Global Analysis by Ponemon Institute. Research studies are placing the blame on the element of portability in electronic health records (EHRs) that has contributed to numerous vulnerabilities to hospital healthcare data. As a result, the healthcare information of patients in those hospitals that are equipped with interconnected medical devices is exposed to cybersecurity threats. The purpose of the study was to develop a healthcare contingency management framework that can be used by healthcare institutions to mitigate cybersecurity threats to EHRs in the public health sector in South Africa. The integrated systems theory (IST) which amalgamated five different theories relating to information security management was used as a theoretical foundation in this study. In achieving this purpose, the literature review was selected as the research design best suited to answer the question presented in this research study. An expert review was used to refine the framework outcome using interviews and questionnaires. The contribution that will be made by this study will be in a form of a conceptual framework that will be used to mitigate cybersecurity threats concerning EHRs in the public health sector. The healthcare contingency management framework (HCMF) can be adopted by either the National Health Department or Provincial Health Department to be used by healthcare facilities as a guide in reviewing their support function, process management, governance management, and their contingency management. Similar future studies need to be conducted on large scale such as in the whole public sector with the focus on the health sector. , Thesis (MA) -- Faculty of Management and Commerce, 2021
- Full Text:
- Date Issued: 2021-11
- Authors: Ngxabane, Mbulelo https://orcid.org/0000-0003-2942-2568
- Date: 2021-11
- Subjects: Health services administration--Information technology , Computer Security
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/23427 , vital:57730
- Description: Most developing countries in the African continent, including South Africa, seem to be lagging behind in research, policy development, and how to prevent cybersecurity threats. These findings are evident in the significant number of cyberattacks recorded in the Cost of Data Breach Study and Global Analysis by Ponemon Institute. Research studies are placing the blame on the element of portability in electronic health records (EHRs) that has contributed to numerous vulnerabilities to hospital healthcare data. As a result, the healthcare information of patients in those hospitals that are equipped with interconnected medical devices is exposed to cybersecurity threats. The purpose of the study was to develop a healthcare contingency management framework that can be used by healthcare institutions to mitigate cybersecurity threats to EHRs in the public health sector in South Africa. The integrated systems theory (IST) which amalgamated five different theories relating to information security management was used as a theoretical foundation in this study. In achieving this purpose, the literature review was selected as the research design best suited to answer the question presented in this research study. An expert review was used to refine the framework outcome using interviews and questionnaires. The contribution that will be made by this study will be in a form of a conceptual framework that will be used to mitigate cybersecurity threats concerning EHRs in the public health sector. The healthcare contingency management framework (HCMF) can be adopted by either the National Health Department or Provincial Health Department to be used by healthcare facilities as a guide in reviewing their support function, process management, governance management, and their contingency management. Similar future studies need to be conducted on large scale such as in the whole public sector with the focus on the health sector. , Thesis (MA) -- Faculty of Management and Commerce, 2021
- Full Text:
- Date Issued: 2021-11
An analysis of small, medium, and micro enteprise contribution to job creation: a case study of the Chris Hani District Municipality
- Authors: Mbotshane, Sibongile
- Date: 2021-11
- Subjects: Job creation -- South Africa -- Eastern Cape , Business enterprises -- South Africa -- Eastern Cape
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/54913 , vital:48472
- Description: It is the norm that job creation becomes the responsibility of entrepreneurs in the area where they operate. The role of the state is legislatively to create a conducive environment for the entrepreneurs to flourish and do their respective businesses in a manner that is beneficial to themselves and the society at large. This study was conducted in Chris Hani District municipality. The district consists of six Local Municipalities where it coordinates their activities and renders support where necessary. Over the past few years, the district has been inundated with requests for financial support from SMMEs. In this regard the researcher undertook to do a follow up in the form of this study to the extent in which the SMMEs contribute to job creation in the district. The study undertook both a qualitative and quantitative approach in ensuring they complement one another and to allow effective engagements with the SMMEs as the core of the study. The sampled respondents/participants in the study were given questionnaires to respond to that would assist the researcher in analysing the raw data and be able to arrive at a particular conclusion in relation to the research questions. Respondents were given an opportunity to respond to questionnaires for a period of two weeks at the comfort of their homes. The results of the study indicate that those firms with a good track record, high annual turnover, sophistication and diverse skills, good credit record, good cash flow, proper financial records, bankable and viable business plans, collateral and registered for VAT were more likely to have a higher impact on the creation of both the short- and long-term employment as they are in a more sustainable position. The conclusion of the study is that the internal factors turned to have the greatest influence on SMME sustainability and job creation in this regard. However, there is more to be done by the private and public SMME support agencies. The study recommends that in-depth empirical research be conducted on the support services provided by private and public SMME support agencies in terms of the services that they offer and the effectiveness of the services and how these are communicated to potential customers. It is also recommended that training workshops aimed at addressing the internal constraints identified be conducted. It is further recommended that the development and implementation of sector-specific mentoring programmes for the owner-managers of the SMMEs be implemented for them to positively contribute to job creation in the region. Strategies to improve the awareness of support services provided by SMME support agencies need to be developed. This would ensure the effective use of these services by SMMEs. It is also recommended that SMME support agencies staff be trained in order to better understand and be more responsive to the owner managers’ needs. , Thesis (MADS) -- Faculty of Business and Economic Sciences, 2021
- Full Text:
- Date Issued: 2021-11
- Authors: Mbotshane, Sibongile
- Date: 2021-11
- Subjects: Job creation -- South Africa -- Eastern Cape , Business enterprises -- South Africa -- Eastern Cape
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/54913 , vital:48472
- Description: It is the norm that job creation becomes the responsibility of entrepreneurs in the area where they operate. The role of the state is legislatively to create a conducive environment for the entrepreneurs to flourish and do their respective businesses in a manner that is beneficial to themselves and the society at large. This study was conducted in Chris Hani District municipality. The district consists of six Local Municipalities where it coordinates their activities and renders support where necessary. Over the past few years, the district has been inundated with requests for financial support from SMMEs. In this regard the researcher undertook to do a follow up in the form of this study to the extent in which the SMMEs contribute to job creation in the district. The study undertook both a qualitative and quantitative approach in ensuring they complement one another and to allow effective engagements with the SMMEs as the core of the study. The sampled respondents/participants in the study were given questionnaires to respond to that would assist the researcher in analysing the raw data and be able to arrive at a particular conclusion in relation to the research questions. Respondents were given an opportunity to respond to questionnaires for a period of two weeks at the comfort of their homes. The results of the study indicate that those firms with a good track record, high annual turnover, sophistication and diverse skills, good credit record, good cash flow, proper financial records, bankable and viable business plans, collateral and registered for VAT were more likely to have a higher impact on the creation of both the short- and long-term employment as they are in a more sustainable position. The conclusion of the study is that the internal factors turned to have the greatest influence on SMME sustainability and job creation in this regard. However, there is more to be done by the private and public SMME support agencies. The study recommends that in-depth empirical research be conducted on the support services provided by private and public SMME support agencies in terms of the services that they offer and the effectiveness of the services and how these are communicated to potential customers. It is also recommended that training workshops aimed at addressing the internal constraints identified be conducted. It is further recommended that the development and implementation of sector-specific mentoring programmes for the owner-managers of the SMMEs be implemented for them to positively contribute to job creation in the region. Strategies to improve the awareness of support services provided by SMME support agencies need to be developed. This would ensure the effective use of these services by SMMEs. It is also recommended that SMME support agencies staff be trained in order to better understand and be more responsive to the owner managers’ needs. , Thesis (MADS) -- Faculty of Business and Economic Sciences, 2021
- Full Text:
- Date Issued: 2021-11
Assessment of compliance to the maintenance procedure of medical equipment in a selected hospital, Oliver Reginald Tambo District, Eastern Cape Province
- Authors: Mbangata, Mzuyanda
- Date: 2021-11
- Subjects: Equipment health monitoring , Maintenance--Equipment and supplies
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/21871 , vital:51838
- Description: Background Medical equipment assumes a major part in diagnosis, prevention and treatment of diseases as well as illness and rehabilitation of patients. The maintenance of medical equipment is one of the most vital components in quality health care service delivery and it should not be ignored in the hospital. Therefore, it is critical that medical equipment must be maintained, and be in good working condition to ensure it completes its life cycle, also to prevent possible injuries to the patients and clinicians/end-users. Proper maintenance of medical equipment needs compliance with the manufacturer’s recommendations. Inappropriate maintenance of medical equipment leads to medical equipment malfunctioning, decreases the level of medical equipment performance, and wastes money and other resources. The equipment downtime makes health care services not accessible to patients. Maintenance includes the following activities, medical equipment acceptance, preventive maintenance, inspection, calibration and repair following the manufacturer’s recommendations. Aim of the study The purpose of the study was to assess compliance to the maintenance procedures of medical equipment in a selected hospital in Oliver Reginald Tambo District, Eastern Cape Province. Methodology A qualitative descriptive design was used to access information regarding compliance with the maintenance of medical equipment in a selected hospital, in Oliver Reginald Tambo District, Eastern Cape. The compliance was accessed at the selected hospital that has eight departments. The research objectives gave a framework for how the research was to be conducted. The data was collected through semi-structured interviews until data saturation. An open coding Tesch’s qualitative method was used for data analysis. A purposive sampling technique was used to select participants who were knowledgeable and responsible for management of medical equipment maintenance. The participants were experienced clinicians and technicians answerable for medical equipment maintenance and management. The researcher adhered to ethical and trustworthiness principles. Findings The following themes and their related categories emerged as compliance procedures adhered to/applied: i) Determinants of applied procedures; ii) Compliance with maintenance that is facilitate frequent checks, daily regular testing of equipment; iii) Report faulty equipment; iv) Send equipment for repairs; v) Do follow up on repairs; and vi) Keep machines working all the time. Contributory factors to non-compliance included: Unavailability of funds; technical staff shortage; lack of technical training; non-compliance in performance of quality checks; lack of training of end users; lack of set of maintenance plans; and long procurement process. Complications aligned with non-compliance: Inappropriate referral patients; inaccessibility of health care services; and misdiagnosing patients. Recommendations The strengthening of clinical engineering department with human resources (technical staff), finance (funds for spare parts) and physical resources (workspace, testing equipment and tools, service manuals etc.) Prioritise medical equipment maintenance also improvement of maintenance budget allocation and utilization. Provision of training for end users and technical staff. Establishment and implementation of maintenance plan and improvement of procurement processes. Conclusion The selected hospital is partially compliant with the maintenance of medical equipment because the hospital performs only reactive maintenance. It evidently appeared that affected service delivery is initiated by the shortage of technical staff and equipment availability and reliability. The hospital needs to focus and improve on the above mentioned factors affecting medical equipment maintenance. The results showed that improper maintenance of medical equipment contributes to the overcrowding of tertiary hospitals through unnecessary referrals due to medical equipment malfunctioning. The study contributes to improving the maintenance management of medical equipment. , Thesis (MPH) -- Faculty of Health Sciences, 2021
- Full Text:
- Date Issued: 2021-11
- Authors: Mbangata, Mzuyanda
- Date: 2021-11
- Subjects: Equipment health monitoring , Maintenance--Equipment and supplies
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/21871 , vital:51838
- Description: Background Medical equipment assumes a major part in diagnosis, prevention and treatment of diseases as well as illness and rehabilitation of patients. The maintenance of medical equipment is one of the most vital components in quality health care service delivery and it should not be ignored in the hospital. Therefore, it is critical that medical equipment must be maintained, and be in good working condition to ensure it completes its life cycle, also to prevent possible injuries to the patients and clinicians/end-users. Proper maintenance of medical equipment needs compliance with the manufacturer’s recommendations. Inappropriate maintenance of medical equipment leads to medical equipment malfunctioning, decreases the level of medical equipment performance, and wastes money and other resources. The equipment downtime makes health care services not accessible to patients. Maintenance includes the following activities, medical equipment acceptance, preventive maintenance, inspection, calibration and repair following the manufacturer’s recommendations. Aim of the study The purpose of the study was to assess compliance to the maintenance procedures of medical equipment in a selected hospital in Oliver Reginald Tambo District, Eastern Cape Province. Methodology A qualitative descriptive design was used to access information regarding compliance with the maintenance of medical equipment in a selected hospital, in Oliver Reginald Tambo District, Eastern Cape. The compliance was accessed at the selected hospital that has eight departments. The research objectives gave a framework for how the research was to be conducted. The data was collected through semi-structured interviews until data saturation. An open coding Tesch’s qualitative method was used for data analysis. A purposive sampling technique was used to select participants who were knowledgeable and responsible for management of medical equipment maintenance. The participants were experienced clinicians and technicians answerable for medical equipment maintenance and management. The researcher adhered to ethical and trustworthiness principles. Findings The following themes and their related categories emerged as compliance procedures adhered to/applied: i) Determinants of applied procedures; ii) Compliance with maintenance that is facilitate frequent checks, daily regular testing of equipment; iii) Report faulty equipment; iv) Send equipment for repairs; v) Do follow up on repairs; and vi) Keep machines working all the time. Contributory factors to non-compliance included: Unavailability of funds; technical staff shortage; lack of technical training; non-compliance in performance of quality checks; lack of training of end users; lack of set of maintenance plans; and long procurement process. Complications aligned with non-compliance: Inappropriate referral patients; inaccessibility of health care services; and misdiagnosing patients. Recommendations The strengthening of clinical engineering department with human resources (technical staff), finance (funds for spare parts) and physical resources (workspace, testing equipment and tools, service manuals etc.) Prioritise medical equipment maintenance also improvement of maintenance budget allocation and utilization. Provision of training for end users and technical staff. Establishment and implementation of maintenance plan and improvement of procurement processes. Conclusion The selected hospital is partially compliant with the maintenance of medical equipment because the hospital performs only reactive maintenance. It evidently appeared that affected service delivery is initiated by the shortage of technical staff and equipment availability and reliability. The hospital needs to focus and improve on the above mentioned factors affecting medical equipment maintenance. The results showed that improper maintenance of medical equipment contributes to the overcrowding of tertiary hospitals through unnecessary referrals due to medical equipment malfunctioning. The study contributes to improving the maintenance management of medical equipment. , Thesis (MPH) -- Faculty of Health Sciences, 2021
- Full Text:
- Date Issued: 2021-11
Big data use at an automotive manufacturer: a framework to address privacy concerns in Hadoop Technology.
- Authors: Padayachee, Prenisha
- Date: 2021-11
- Subjects: Data protection. , Privacy, Right of. , Computer networks--Security measures.
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/22255 , vital:52009
- Description: An automotive manufacturer can generate big data through accessible data points from internal and external Internet of Things (IoT) data sources connected to the production line. Big data analytics needs to be applied to these large and complex datasets to realise the associated opportunities, such as an improved manufacturing process, optimised supply chain management, competitive advantage and business growth. In order to store, manage and process the data, automotive manufacturers are using Apache Hadoop technology. Apache Hadoop is a cost-effective, scalable, and fault-tolerant technology. However, there has been a concern raised regarding the privacy of big data in Apache Hadoop. A key challenge in Hadoop technology is its ineffective security model, making the data susceptible to unauthorised users. Consequently, a breach in data privacy results in automotive manufacturers becoming victims of theft of trade secrets and intellectual property via corporate spies. This theft has a negative impact and results in the loss of company reputation, business competitiveness and business growth in the automotive market. This study investigated a solution to ensure big data privacy when using Hadoop technology. The Selective Organisational Information Privacy and Security Violations Model (SOIPSVM) and the Capability Maturity Model (CMM) provided the theoretical base for this study. The researcher undertook a literature analysis and qualitative study to understand and address the identified research problem. The primary data was collected from ten Information Technology (IT) specialists at a local automotive manufacturer. These specialists participated in an interview session, which also included the completion of a questionnaire. All questions were pre-determined and open-ended, and the participants' responses were recorded. Primary data was analysed using the inductive approach by identifying relevant themes and sub-themes. In contrast, the literature analysis included academic journals, conference proceedings, websites, and books, which were critically discussed in this study. This study's findings indicated various measures to be implemented by the automotive manufacturer to address the research problem. Critical success factors were derived from the identified measures, which addressed significant data privacy issues in using Hadoop technology. The identified critical success factors included: control of internal and external data sources; monitor the value of big data towards improving the automotive manufacturing process and user behaviour; implementation of user authentication; encryption to secure data; disaster recovery and backup plan; execution of authorisation and Access Control List (ACLS); conduct audits and regular reviews of user access to data; apply data masking to sensitive data and tokenization to secure data; build own infrastructure to store and analyse data; install regular security updates and update passwords regularly. Each factor had a purpose that examined big data management, governance and compliance in detail. The identified factors contributed towards ensuring data privacy in the use of Hadoop technology. These factors were categorised into contextual and rule and regulatory conditions adopted from the SOIPSVM. Identified conditions were then aligned to the five-level CMM. Each condition was expanded upon at various maturity levels to form a framework that addressed the main research problem. The framework's application was described as an independent assessment of each critical success factor and provided a guide through various maturity levels. The framework's purpose was to address and overcome big data privacy concerns in using Hadoop technology at a local automotive manufacturer. , Thesis (MCom) (Information Systems) -- University of Fort Hare, 2021
- Full Text:
- Date Issued: 2021-11
- Authors: Padayachee, Prenisha
- Date: 2021-11
- Subjects: Data protection. , Privacy, Right of. , Computer networks--Security measures.
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/22255 , vital:52009
- Description: An automotive manufacturer can generate big data through accessible data points from internal and external Internet of Things (IoT) data sources connected to the production line. Big data analytics needs to be applied to these large and complex datasets to realise the associated opportunities, such as an improved manufacturing process, optimised supply chain management, competitive advantage and business growth. In order to store, manage and process the data, automotive manufacturers are using Apache Hadoop technology. Apache Hadoop is a cost-effective, scalable, and fault-tolerant technology. However, there has been a concern raised regarding the privacy of big data in Apache Hadoop. A key challenge in Hadoop technology is its ineffective security model, making the data susceptible to unauthorised users. Consequently, a breach in data privacy results in automotive manufacturers becoming victims of theft of trade secrets and intellectual property via corporate spies. This theft has a negative impact and results in the loss of company reputation, business competitiveness and business growth in the automotive market. This study investigated a solution to ensure big data privacy when using Hadoop technology. The Selective Organisational Information Privacy and Security Violations Model (SOIPSVM) and the Capability Maturity Model (CMM) provided the theoretical base for this study. The researcher undertook a literature analysis and qualitative study to understand and address the identified research problem. The primary data was collected from ten Information Technology (IT) specialists at a local automotive manufacturer. These specialists participated in an interview session, which also included the completion of a questionnaire. All questions were pre-determined and open-ended, and the participants' responses were recorded. Primary data was analysed using the inductive approach by identifying relevant themes and sub-themes. In contrast, the literature analysis included academic journals, conference proceedings, websites, and books, which were critically discussed in this study. This study's findings indicated various measures to be implemented by the automotive manufacturer to address the research problem. Critical success factors were derived from the identified measures, which addressed significant data privacy issues in using Hadoop technology. The identified critical success factors included: control of internal and external data sources; monitor the value of big data towards improving the automotive manufacturing process and user behaviour; implementation of user authentication; encryption to secure data; disaster recovery and backup plan; execution of authorisation and Access Control List (ACLS); conduct audits and regular reviews of user access to data; apply data masking to sensitive data and tokenization to secure data; build own infrastructure to store and analyse data; install regular security updates and update passwords regularly. Each factor had a purpose that examined big data management, governance and compliance in detail. The identified factors contributed towards ensuring data privacy in the use of Hadoop technology. These factors were categorised into contextual and rule and regulatory conditions adopted from the SOIPSVM. Identified conditions were then aligned to the five-level CMM. Each condition was expanded upon at various maturity levels to form a framework that addressed the main research problem. The framework's application was described as an independent assessment of each critical success factor and provided a guide through various maturity levels. The framework's purpose was to address and overcome big data privacy concerns in using Hadoop technology at a local automotive manufacturer. , Thesis (MCom) (Information Systems) -- University of Fort Hare, 2021
- Full Text:
- Date Issued: 2021-11