Association between maternal health status and birth outcomes in the Nelson Mandela Bay Health District
- Authors: Hawkins, Althea Anita
- Date: 2018
- Subjects: Birth weight, Low -- Nelson Mandela Bay Municipality , Birth weight Premature infants
- Language: English
- Type: Thesis , Masters , MCur
- Identifier: http://hdl.handle.net/10948/30039 , vital:30812
- Description: In 2011, the South African low birth weight rates varied between 9% and 15.5%, according to different sources. This means that about one out of every ten babies born alive weighed less than 2500g. Furthermore, six of South Africa’s nine provinces, including the Eastern Cape, reported low birth weight rates equal or higher than the national average. These figures raise serious concerns about the health status of infants, their chances of survival and their quality of life, particularly in provinces with a high incidence of low birth weight. Literature has linked the maternal health status to adverse birth outcomes. Statistics from the district office of the Nelson Mandela Bay Health District (NMBHD) indicates that for the fourth quarter of 2015, between 16.65 and 20.9% low birth weight infants were born. However, limited information is available regarding the causes and maternal health status of the mothers of the infants born with adverse birth outcomes in the Nelson Mandela Bay Health District (NMBHD). The objective of the research study is to investigate the associations between maternal health status and birth outcomes in order to identify the major drivers of adverse birth outcomes in NMBHD. The study used a quantitative research approach. In order to enhance the design, the researcher used an explorative, descriptive, cross-sectional, contextual and survey research design. The study was conducted at the regional hospital in Nelson Mandela Bay Health District (NMBHD) and Midwifery Obstetric Units (MOU). The participants were selected using a convenient and purposive sampling technique. A structured, self-administered questionnaire was used as the data collection tool. A statistician assisted with the data analysis. Descriptive and inferential statistics were used. The researcher ensured that ethical considerations were maintained throughout the study to protect the participants. Reliability and validity were also ensured throughout the study. The total sample of the study was 207 and the mean age of the participants was 26,9 years. Hypertension and HIV were the conditions most diagnosed prior to, and during, pregnancy. Most of the delivered infants were females. The findings of the study revealed a significant association between maternal diabetes, maternal hypertension and the infants’ birth weight. Additional findings iv revealed that independent of gestational age, mothers with hypertension are likely to deliver low birth weight (LBW) infants. Antenatal care is of the utmost importance during pregnancy and special attention should be given to the management of hypertension. The researcher developed recommendations for primary health care (PHC) nurses in antenatal clinics (ANC) to address the management of the major maternal drivers of LBW infants in order to decrease and prevent adverse birth outcomes.
- Full Text:
- Date Issued: 2018
- Authors: Hawkins, Althea Anita
- Date: 2018
- Subjects: Birth weight, Low -- Nelson Mandela Bay Municipality , Birth weight Premature infants
- Language: English
- Type: Thesis , Masters , MCur
- Identifier: http://hdl.handle.net/10948/30039 , vital:30812
- Description: In 2011, the South African low birth weight rates varied between 9% and 15.5%, according to different sources. This means that about one out of every ten babies born alive weighed less than 2500g. Furthermore, six of South Africa’s nine provinces, including the Eastern Cape, reported low birth weight rates equal or higher than the national average. These figures raise serious concerns about the health status of infants, their chances of survival and their quality of life, particularly in provinces with a high incidence of low birth weight. Literature has linked the maternal health status to adverse birth outcomes. Statistics from the district office of the Nelson Mandela Bay Health District (NMBHD) indicates that for the fourth quarter of 2015, between 16.65 and 20.9% low birth weight infants were born. However, limited information is available regarding the causes and maternal health status of the mothers of the infants born with adverse birth outcomes in the Nelson Mandela Bay Health District (NMBHD). The objective of the research study is to investigate the associations between maternal health status and birth outcomes in order to identify the major drivers of adverse birth outcomes in NMBHD. The study used a quantitative research approach. In order to enhance the design, the researcher used an explorative, descriptive, cross-sectional, contextual and survey research design. The study was conducted at the regional hospital in Nelson Mandela Bay Health District (NMBHD) and Midwifery Obstetric Units (MOU). The participants were selected using a convenient and purposive sampling technique. A structured, self-administered questionnaire was used as the data collection tool. A statistician assisted with the data analysis. Descriptive and inferential statistics were used. The researcher ensured that ethical considerations were maintained throughout the study to protect the participants. Reliability and validity were also ensured throughout the study. The total sample of the study was 207 and the mean age of the participants was 26,9 years. Hypertension and HIV were the conditions most diagnosed prior to, and during, pregnancy. Most of the delivered infants were females. The findings of the study revealed a significant association between maternal diabetes, maternal hypertension and the infants’ birth weight. Additional findings iv revealed that independent of gestational age, mothers with hypertension are likely to deliver low birth weight (LBW) infants. Antenatal care is of the utmost importance during pregnancy and special attention should be given to the management of hypertension. The researcher developed recommendations for primary health care (PHC) nurses in antenatal clinics (ANC) to address the management of the major maternal drivers of LBW infants in order to decrease and prevent adverse birth outcomes.
- Full Text:
- Date Issued: 2018
Educating children presenting with autistic spectrum disorders: exploring parents' experiences
- Authors: McGrath, Wanita
- Date: 2015
- Subjects: Autistic children -- Education , Autistic children
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10948/10265 , vital:26647
- Description: According to Pienaar and Raymond (2013, p.10) learners with disabilities have historically experienced the most serious exclusion from learning. The worldwide call for inclusive education prompted South Africa to develop the White Paper 6 (WP6) (2001, p.18) which clearly states that for Inclusive Education to be successfully implemented in South Africa, there has to be an acknowledgement that all children and youth can learn. The implementation of WP6 therefore not only benefits learners with special educational needs, but all South African learners by implementing "a more flexible system of education that focuses on removing barriers to learning and creating learning-friendly environments" (Pienaar and Raymond, 2013, pp. 10-11). However, a great disparity exists in what is proposed in official documents such as WP6 and what parents of children with barriers to learning actually experience within schools. This phenomenological study employed memory work, drawings and focus group discussions with four purposively selected parents to explore parents’ experiences of the education of their children who are on the Autistic Spectrum. Bronfenbrenner’s Eco-systemic perspective was used to make meaning of the data. The findings show that parents find the education of their autistic children as a stressful and isolating experience because of an unprepared education system. Despite the challenges, the participants also find their experiences to be a journey of personal growth and fulfilment. The study therefore recommends that schools should engage parents of autistic children more actively in order to make inclusion of such children effective. Teachers who are expected to practice inclusivity in schools should be adequately prepared to work with children presenting with ASD through a collaborative effort of the Department of Health and the Department of Education.
- Full Text:
- Date Issued: 2015
- Authors: McGrath, Wanita
- Date: 2015
- Subjects: Autistic children -- Education , Autistic children
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10948/10265 , vital:26647
- Description: According to Pienaar and Raymond (2013, p.10) learners with disabilities have historically experienced the most serious exclusion from learning. The worldwide call for inclusive education prompted South Africa to develop the White Paper 6 (WP6) (2001, p.18) which clearly states that for Inclusive Education to be successfully implemented in South Africa, there has to be an acknowledgement that all children and youth can learn. The implementation of WP6 therefore not only benefits learners with special educational needs, but all South African learners by implementing "a more flexible system of education that focuses on removing barriers to learning and creating learning-friendly environments" (Pienaar and Raymond, 2013, pp. 10-11). However, a great disparity exists in what is proposed in official documents such as WP6 and what parents of children with barriers to learning actually experience within schools. This phenomenological study employed memory work, drawings and focus group discussions with four purposively selected parents to explore parents’ experiences of the education of their children who are on the Autistic Spectrum. Bronfenbrenner’s Eco-systemic perspective was used to make meaning of the data. The findings show that parents find the education of their autistic children as a stressful and isolating experience because of an unprepared education system. Despite the challenges, the participants also find their experiences to be a journey of personal growth and fulfilment. The study therefore recommends that schools should engage parents of autistic children more actively in order to make inclusion of such children effective. Teachers who are expected to practice inclusivity in schools should be adequately prepared to work with children presenting with ASD through a collaborative effort of the Department of Health and the Department of Education.
- Full Text:
- Date Issued: 2015
An ERP system implementation framework for management accountants in the water industry
- Authors: Mudau, Thanyani Norman
- Date: 2012
- Subjects: Management information systems , Enterprise resource planning , Business planning
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:10487 , http://hdl.handle.net/10948/d1018921
- Description: Organisations are seeking for an opportunity to reduce costs while they increase service delivery to their customers. In order to remain in business, companies must have proper strategies in place to reduce costs while they still deliver the same standard of service. In order to remain competitive, companies have implemented Information Communication Technology (ICT). The implementation of ICT was done to assist organisations to improve efficiency in their production processes. To achieve these objectives, companies implemented Enterprise Resource Planning (ERP) systems. Some companies that have implemented an ERP system, however, are faced with the challenge of not fully realising the full benefits of implementing the ERP system. The Water Industry is faced with a challenge of ensuring that it manages the water value chain effectively through the use of an ERP system. The industry is also experiencing difficult times in ensuring that the business is run in a sustainable manner to manage the infrastructure assets. This has resulted in the importance of internal reporting within the Water Industry to assist management to monitor performance and take informed decisions. The implementation of an ERP system has affected all the roles in the Water Industry, especially the role of management accountants who are involved with internal reporting. Management accountants are experiencing challenges during and after the implementation of an ERP system, especially with the effective and efficient reporting of information. This study investigated the challenges that management accountants encountered after the implementation of an ERP system in the Water Industry in South Africa. The research consists of a preliminary study to identify challenges that management accountants encounter during and after the implementation of ERP system in the Water Industry. A literature review on the role of management accountants combined with the ERP system applications and framework are investigated and an ERP system implementation framework for the Water Industry is proposed. The proposed framework is evaluated and recommendations are made to those involved with the water industry that are considering upgrading or implementing an ERP system.
- Full Text:
- Date Issued: 2012
- Authors: Mudau, Thanyani Norman
- Date: 2012
- Subjects: Management information systems , Enterprise resource planning , Business planning
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:10487 , http://hdl.handle.net/10948/d1018921
- Description: Organisations are seeking for an opportunity to reduce costs while they increase service delivery to their customers. In order to remain in business, companies must have proper strategies in place to reduce costs while they still deliver the same standard of service. In order to remain competitive, companies have implemented Information Communication Technology (ICT). The implementation of ICT was done to assist organisations to improve efficiency in their production processes. To achieve these objectives, companies implemented Enterprise Resource Planning (ERP) systems. Some companies that have implemented an ERP system, however, are faced with the challenge of not fully realising the full benefits of implementing the ERP system. The Water Industry is faced with a challenge of ensuring that it manages the water value chain effectively through the use of an ERP system. The industry is also experiencing difficult times in ensuring that the business is run in a sustainable manner to manage the infrastructure assets. This has resulted in the importance of internal reporting within the Water Industry to assist management to monitor performance and take informed decisions. The implementation of an ERP system has affected all the roles in the Water Industry, especially the role of management accountants who are involved with internal reporting. Management accountants are experiencing challenges during and after the implementation of an ERP system, especially with the effective and efficient reporting of information. This study investigated the challenges that management accountants encountered after the implementation of an ERP system in the Water Industry in South Africa. The research consists of a preliminary study to identify challenges that management accountants encounter during and after the implementation of ERP system in the Water Industry. A literature review on the role of management accountants combined with the ERP system applications and framework are investigated and an ERP system implementation framework for the Water Industry is proposed. The proposed framework is evaluated and recommendations are made to those involved with the water industry that are considering upgrading or implementing an ERP system.
- Full Text:
- Date Issued: 2012
Antibacterial activity of liposome encapsulated cyclo(TYR-PRO)
- Authors: Tshanga, Siphokazi Sisanda
- Date: 2011
- Subjects: Peptide antibiotics , Antibacterial agents -- Therapeutic use -- Testing
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:10132 , http://hdl.handle.net/10948/1450 , Peptide antibiotics , Antibacterial agents -- Therapeutic use -- Testing
- Description: Cyclic dipeptides (CDPs) are amino acid-based compounds, some of which possess antibacterial activity. The encapsulation of certain drugs into liposomes has been found to improve their activity in terms of bioavailability and duration of action. Liposomes are small vesicles that are under investigation as drug carriers for the delivery of therapeutic agents. A number of liposome formulations are currently under clinical trial review, whilst some have already been approved for clinical use. The aim of this study was to optimize a liposomal cyclo(Tyr-Pro) formulation and to assess its antibacterial activity against various Gram-positive and Gram-negative bacteria. Response surface methodology (RSM) using the central composite design (CCD) model was used to optimize liposomal formulations of cyclo(Tyr-Pro) for each of the four bacteria, namely Bacillus cereus, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. Percent drug encapsulated and bacterial inhibition were investigated with respect to two independent variables, i.e. lipid composition and cholesterol content. Design Expert 8 was used for the purpose of finding the combination of independent variables that would yield an optimal formulation for each bacterium. The model selected by the software failed to adequately correlate the predicted models to the experimental data. The in vitro experiments showed that the antibacterial activity of liposome-encapsulated cyclo(Tyr-Pro) was superior to that of its free counterpart. Binding maximum or Bmax for the encapsulated compound at concentrations as low as 0.412 mg/ml, was significantly higher than that obtained for free cyclo(Tyr-Pro) which was tested at a concentration of 20 mg/ml. Furthermore, encapsulation of cyclo(Tyr-Pro) into a liposome formulation enhanced its potency. This was evident in the lower IC50 values for the liposomal compound when compared to free cyclo(Tyr-Pro).
- Full Text:
- Date Issued: 2011
- Authors: Tshanga, Siphokazi Sisanda
- Date: 2011
- Subjects: Peptide antibiotics , Antibacterial agents -- Therapeutic use -- Testing
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:10132 , http://hdl.handle.net/10948/1450 , Peptide antibiotics , Antibacterial agents -- Therapeutic use -- Testing
- Description: Cyclic dipeptides (CDPs) are amino acid-based compounds, some of which possess antibacterial activity. The encapsulation of certain drugs into liposomes has been found to improve their activity in terms of bioavailability and duration of action. Liposomes are small vesicles that are under investigation as drug carriers for the delivery of therapeutic agents. A number of liposome formulations are currently under clinical trial review, whilst some have already been approved for clinical use. The aim of this study was to optimize a liposomal cyclo(Tyr-Pro) formulation and to assess its antibacterial activity against various Gram-positive and Gram-negative bacteria. Response surface methodology (RSM) using the central composite design (CCD) model was used to optimize liposomal formulations of cyclo(Tyr-Pro) for each of the four bacteria, namely Bacillus cereus, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. Percent drug encapsulated and bacterial inhibition were investigated with respect to two independent variables, i.e. lipid composition and cholesterol content. Design Expert 8 was used for the purpose of finding the combination of independent variables that would yield an optimal formulation for each bacterium. The model selected by the software failed to adequately correlate the predicted models to the experimental data. The in vitro experiments showed that the antibacterial activity of liposome-encapsulated cyclo(Tyr-Pro) was superior to that of its free counterpart. Binding maximum or Bmax for the encapsulated compound at concentrations as low as 0.412 mg/ml, was significantly higher than that obtained for free cyclo(Tyr-Pro) which was tested at a concentration of 20 mg/ml. Furthermore, encapsulation of cyclo(Tyr-Pro) into a liposome formulation enhanced its potency. This was evident in the lower IC50 values for the liposomal compound when compared to free cyclo(Tyr-Pro).
- Full Text:
- Date Issued: 2011
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