Development of an antiretroviral solid dosage form using multivariate analysis

Title: Development of an antiretroviral solid dosage form using multivariate analysis
Creator: Nqabeni, Luxolo
Subject: Analysis of variance
Subject: Experimental design
Subject: Multivariate analysis
Subject: Antiretroviral agents -- South Africa
Date Issued: 2007
Date: 2007
Type: Thesis
Type: Masters
Type: MSc
Identifier: vital:10145
Identifier: http://hdl.handle.net/10948/705
Identifier: Analysis of variance
Identifier: Experimental design
Identifier: Multivariate analysis
Identifier: Antiretroviral agents -- South Africa
Description: The aim of pharmaceutical development is to design a quality product and the manufacturing process to deliver the product in a reproducible manner. The development of a new and generic formulation is based on a large number of experiments. Statistics provides many tools for studying the conditions of formulations and processes and enables us to optimize the same while being able to minimize our experimentation. The purpose of this study was to apply experimental design methodology (DOE) and multivariate analysis to the development and optimization of tablet formulations containing 150 mg lamivudine manufactured by direct compression.
Format: xiii, 163 leaves
Format: pdf
Publisher: Nelson Mandela Metropolitan University
Publisher: Faculty of Health Sciences
Language: English
Rights: Nelson Mandela Metropolitan University

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NMMU School of Medicinal Sciences

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