Knowledge, attitudes and practises of professional nurses working with patients with tuberculosis in the Nelson Mandela Bay Health District
- Authors: Nxumalo, Avela
- Date: 2018
- Subjects: Tuberculosis -- Patients -- South Africa -- Nelson Mandela Bay Municipality , Tuberculosis -- Treatment -- South Africa -- Nelson Mandela Bay Municipality Primary health care -- South Africa -- Nelson Mandela Bay Municipality , Professional Nursing -- Dissertations
- Language: English
- Type: Thesis , Masters , MCur
- Identifier: http://hdl.handle.net/10948/33715 , vital:32994
- Description: Tuberculosis (TB) is one of the major public health problems worldwide, and includes the development of drug resistant TB. Tuberculosis is reportedly the second most common infectious cause of death worldwide and thus a global threat. In 2014, 9.6 million people were estimated to have TB and 1.5 million people died of the disease worldwide. South Africa is one of the African countries with the highest burden of TB with 1% of the population of about 50 000 000 who develop the TB disease each year. The research study explored and described the knowledge, attitudes and practices of professional nurses working with patients with TB in primary health care clinics in the Nelson Mandela Bay Health District (NMBHD). A quantitative, exploratory, descriptive and contextual research design was used to operationalise the research objectives. The target population comprised professional nurses in primary health care clinics. Consecutive sampling, a type of non-probability sampling, was used in this study. Descriptive data analysis was applied to analyse and describe the data using the data analysis software programme Statistica Version 11. The majority of the participants (99%) had a high level of knowledge about the cause of TB as well as the question about contracting TB (94.9%). On the TB diagnostic tests: biopsy and sputum culture and sensitivity scored the lowest (22.2% and 36.4% respectively). Regarding the duration of TB treatment and the drug used to prevent TB most participants responded positively (97% and 91.9% respectively). Most of the participants had a positive attitude regarding TB (79.8%) confirming their willingness to wear masks although it makes them uncomfortable. Furthermore, most participants (99%) would like to be screened for TB if they have signs and symptoms suggestive of TB. The majority of participants (99%) responded positively to completing TB treatment if they were to be diagnosed with TB. The practices of professional nurses regarding TB were generally low (18.2%) in the areas of when to wear a mask, ventilation in the clinics and infection control. The results are displayed graphically using bar graphs and tables. Recommendations to the NMBHD were made and also for nursing practice, education, and research. Ethical principles have been maintained throughout the study.
- Full Text:
- Date Issued: 2018
- Authors: Nxumalo, Avela
- Date: 2018
- Subjects: Tuberculosis -- Patients -- South Africa -- Nelson Mandela Bay Municipality , Tuberculosis -- Treatment -- South Africa -- Nelson Mandela Bay Municipality Primary health care -- South Africa -- Nelson Mandela Bay Municipality , Professional Nursing -- Dissertations
- Language: English
- Type: Thesis , Masters , MCur
- Identifier: http://hdl.handle.net/10948/33715 , vital:32994
- Description: Tuberculosis (TB) is one of the major public health problems worldwide, and includes the development of drug resistant TB. Tuberculosis is reportedly the second most common infectious cause of death worldwide and thus a global threat. In 2014, 9.6 million people were estimated to have TB and 1.5 million people died of the disease worldwide. South Africa is one of the African countries with the highest burden of TB with 1% of the population of about 50 000 000 who develop the TB disease each year. The research study explored and described the knowledge, attitudes and practices of professional nurses working with patients with TB in primary health care clinics in the Nelson Mandela Bay Health District (NMBHD). A quantitative, exploratory, descriptive and contextual research design was used to operationalise the research objectives. The target population comprised professional nurses in primary health care clinics. Consecutive sampling, a type of non-probability sampling, was used in this study. Descriptive data analysis was applied to analyse and describe the data using the data analysis software programme Statistica Version 11. The majority of the participants (99%) had a high level of knowledge about the cause of TB as well as the question about contracting TB (94.9%). On the TB diagnostic tests: biopsy and sputum culture and sensitivity scored the lowest (22.2% and 36.4% respectively). Regarding the duration of TB treatment and the drug used to prevent TB most participants responded positively (97% and 91.9% respectively). Most of the participants had a positive attitude regarding TB (79.8%) confirming their willingness to wear masks although it makes them uncomfortable. Furthermore, most participants (99%) would like to be screened for TB if they have signs and symptoms suggestive of TB. The majority of participants (99%) responded positively to completing TB treatment if they were to be diagnosed with TB. The practices of professional nurses regarding TB were generally low (18.2%) in the areas of when to wear a mask, ventilation in the clinics and infection control. The results are displayed graphically using bar graphs and tables. Recommendations to the NMBHD were made and also for nursing practice, education, and research. Ethical principles have been maintained throughout the study.
- Full Text:
- Date Issued: 2018
Microencapsulation of anti-tuberculosis drugs using sporopollenin
- Authors: Mhlana, Kanyisile
- Date: 2017
- Subjects: Mycobacterium tuberculosis -- South Africa -- Prevention Microencapsulation , Plant spores
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10948/13912 , vital:27357
- Description: In this thesis, we explore the benefits of microencapsulating isoniazid and pyrazinamide within sporopollenin exine capsules derived from Lycopodium clavatum. Sporopollenin is a natural biopolymer, which is extracted from the outer shell of pollen grains. These hollow microcapsules can encapsulate and release drug actives in a controlled manner and possess many other advantages such as homogeneity in morphology and size, resilience to both strong acids and bases, they have antioxidant properties as well as UV protection to protect the material inside the microcapsule. Compared to artificial microcapsules, sporopollenin’s muco-adhesion to intestinal tissues contributes greatly to the extended contact of the sporopollenin with the intestines leading to an increased efficiency of delivery of drugs. The hollow microcapsules can be easily filled with a solution of the active or active in a liquid form by simply mixing both together. The drug actives are released in the human body depending on pH factors. Active release can otherwise have controlled by adding a coating on the shell, or co-encapsulation with the active inside the shell so that high drug concentrations are delivered to the site of infection. Encapsulation of the drug active will possibly improve therapeutic abilities of the drugs; simplify the treatment of TB-HIV coinfections by eliminating troublesome drug-drug interactions and drastically reduce or eliminates side effects. The SECs were loaded using a passive filling method. The drug active (0.1 g) was dissolved in a solvent and mixed with the SECs (0.1 g) for 10 minutes. After mixing for 10 minutes, the solvent was removed by a rotary evaporator and dried to a constant mass. The surface of the sporopollenin exines were analysed on a FTIR to observe if there are any drug deposits on the surface of the SECs. The loading efficiency and drug release percentage was determined by using calibrations curves and analysed on a UV-vis spectrophotometer. Further work has been proposed in which to characterize the SECs further and producing coated tablets from loaded SECs.
- Full Text:
- Date Issued: 2017
- Authors: Mhlana, Kanyisile
- Date: 2017
- Subjects: Mycobacterium tuberculosis -- South Africa -- Prevention Microencapsulation , Plant spores
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10948/13912 , vital:27357
- Description: In this thesis, we explore the benefits of microencapsulating isoniazid and pyrazinamide within sporopollenin exine capsules derived from Lycopodium clavatum. Sporopollenin is a natural biopolymer, which is extracted from the outer shell of pollen grains. These hollow microcapsules can encapsulate and release drug actives in a controlled manner and possess many other advantages such as homogeneity in morphology and size, resilience to both strong acids and bases, they have antioxidant properties as well as UV protection to protect the material inside the microcapsule. Compared to artificial microcapsules, sporopollenin’s muco-adhesion to intestinal tissues contributes greatly to the extended contact of the sporopollenin with the intestines leading to an increased efficiency of delivery of drugs. The hollow microcapsules can be easily filled with a solution of the active or active in a liquid form by simply mixing both together. The drug actives are released in the human body depending on pH factors. Active release can otherwise have controlled by adding a coating on the shell, or co-encapsulation with the active inside the shell so that high drug concentrations are delivered to the site of infection. Encapsulation of the drug active will possibly improve therapeutic abilities of the drugs; simplify the treatment of TB-HIV coinfections by eliminating troublesome drug-drug interactions and drastically reduce or eliminates side effects. The SECs were loaded using a passive filling method. The drug active (0.1 g) was dissolved in a solvent and mixed with the SECs (0.1 g) for 10 minutes. After mixing for 10 minutes, the solvent was removed by a rotary evaporator and dried to a constant mass. The surface of the sporopollenin exines were analysed on a FTIR to observe if there are any drug deposits on the surface of the SECs. The loading efficiency and drug release percentage was determined by using calibrations curves and analysed on a UV-vis spectrophotometer. Further work has been proposed in which to characterize the SECs further and producing coated tablets from loaded SECs.
- Full Text:
- Date Issued: 2017
The relationship between employer branding and organisational commitment
- Authors: Tryfonos, Angelique
- Date: 2015
- Subjects: Corporate culture , Organizational commitment , Psychology, Industrial
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9419 , http://hdl.handle.net/10948/d1021146
- Description: The aim of this study was to determine whether a relationship exists between organisational commitment (OC) and employer branding (EB). The purpose was to Identifying whether employer branding effects organisational commitment (affective, normative and continuance commitment) and how significant that effect may be. Questionnaires were personally distributed by the researcher directly to employees under study. Non-probability sampling was used in the form of judgement sampling. The sample consisted of 124 employees from various retail outlets throughout Port Elizabeth, Eastern Cape. Five hypotheses were set for evaluation. A practically significant relationship was established between organisational commitment (OC) and employer branding (EB). A small practically significant relationship was found between gender and normative commitment. A medium practically significant relationship was found between gender and training and development as well as between gender and work/life balance. Statistically significant relationships were discovered with regards to age and leadership and also between age and rewards and recognition. A statistically significant difference was established between age and overall employer branding (EB). These findings suggest that a more positive employer brand will lead to improved organisational commitment (OC). More so, retail organisations aiming to improve on organisational commitment should incorporate those employer branding (EB) factors which employees’ place greater emphasis on, within their employer brand, which in turn will lead to greater organisational commitment.
- Full Text:
- Date Issued: 2015
- Authors: Tryfonos, Angelique
- Date: 2015
- Subjects: Corporate culture , Organizational commitment , Psychology, Industrial
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9419 , http://hdl.handle.net/10948/d1021146
- Description: The aim of this study was to determine whether a relationship exists between organisational commitment (OC) and employer branding (EB). The purpose was to Identifying whether employer branding effects organisational commitment (affective, normative and continuance commitment) and how significant that effect may be. Questionnaires were personally distributed by the researcher directly to employees under study. Non-probability sampling was used in the form of judgement sampling. The sample consisted of 124 employees from various retail outlets throughout Port Elizabeth, Eastern Cape. Five hypotheses were set for evaluation. A practically significant relationship was established between organisational commitment (OC) and employer branding (EB). A small practically significant relationship was found between gender and normative commitment. A medium practically significant relationship was found between gender and training and development as well as between gender and work/life balance. Statistically significant relationships were discovered with regards to age and leadership and also between age and rewards and recognition. A statistically significant difference was established between age and overall employer branding (EB). These findings suggest that a more positive employer brand will lead to improved organisational commitment (OC). More so, retail organisations aiming to improve on organisational commitment should incorporate those employer branding (EB) factors which employees’ place greater emphasis on, within their employer brand, which in turn will lead to greater organisational commitment.
- Full Text:
- Date Issued: 2015
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