Seed extract of Psoralea corylifolia and its constituent bakuchiol impairs AHL-based quorum sensing and biofilm formation in food-and human-related pathogens

Husain, Fohad M; Ahmad, Iqbal; Khan, Faez I; Al-Shabib, Nasser A; Baig, Mohammad H; Hussain, Afzal; Rehman, Md T; Alajmi, Mohamed F; Lobb, Kevin A

Title: Seed extract of Psoralea corylifolia and its constituent bakuchiol impairs AHL-based quorum sensing and biofilm formation in food-and human-related pathogens
Creator: Husain, Fohad M
Creator: Ahmad, Iqbal
Creator: Khan, Faez I
Creator: Al-Shabib, Nasser A
Creator: Baig, Mohammad H
Creator: Hussain, Afzal
Creator: Rehman, Md T
Creator: Alajmi, Mohamed F
Creator: Lobb, Kevin A
Subject: To be catalogued
Date Issued: 2018
Date: 2018
Type: text
Type: article
Identifier: http://hdl.handle.net/10962/447182
Identifier: vital:74590
Identifier: xlink:href="https://doi.org/10.3389/fcimb.2018.00351"
Description: The emergence of multi-drug resistance in pathogenic bacteria in clinical settings as well as food-borne infections has become a serious health concern. The problem of drug resistance necessitates the need for alternative novel therapeutic strategies to combat this menace. One such approach is targeting the quorum-sensing (QS) controlled virulence and biofilm formation. In this study, we first screened different fractions of Psoralea corylifolia (seed) for their anti-QS property in the Chromobacterium violaceum 12472 strain.
Format: computer
Format: online resource
Format: application/pdf
Format: 1 online resource (16 pages)
Format: pdf
Publisher: Frontiers
Language: English
Relation: Frontiers in cellular and infection microbiology
Relation: Husain, F.M., Ahmad, I., Khan, F.I., Al-Shabib, N.A., Baig, M.H., Hussain, A., Rehman, M.T., Alajmi, M.F. and Lobb, K.A., 2018. Seed extract of Psoralea corylifolia and its constituent bakuchiol impairs AHL-based quorum sensing and biofilm formation in food-and human-related pathogens. Frontiers in cellular and infection microbiology, 8, p.351
Relation: Frontiers in cellular and infection microbiology volume 8 p. 351 2018 2235-2988
Rights: Publisher
Rights: Use of this resource is governed by the terms and conditions of the Frontiers Terms and Conditions Statement (https://www.frontiersin.org/legal/terms-and-conditions)
Rights: Open Access

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RU Department of Chemistry

SDG 03. Good Health and Well-Being

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