Lazarus in the Constitutional Court: an exhumation of the exceptio doli generalis
- Authors: Glover, Graham B
- Date: 2007
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/70678 , vital:29688 , https://hdl.handle.net/10520/EJC53775
- Description: A landmark moment in the history of South African contract law was the emphatic interment of the exceptio doli generalis by Joubert JA in Bank of Lisbon and South Africa v De Ornelas 1988 (3) SA580 (A). Throughout most of the twentieth century, the exceptio doli generalis had been viewed as an equitable defence that allowed a defendant to resist a claim for performance under a contract when there was something unconscionable about the plaintiff's seeking to enforce the contract (or a clause thereof) in the specific circumstances of that case (see A J Kerr Principles of the Law of Contract 6 ed (2002) 637ff; P J Aronstam 'Unconscionable contracts: The South African solution?' (1979) 42 THRHR 21; P van Warmelo 'Exceptio doli' 1981 De Jure 202).
- Full Text: false
- Date Issued: 2007
- Authors: Glover, Graham B
- Date: 2007
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/70678 , vital:29688 , https://hdl.handle.net/10520/EJC53775
- Description: A landmark moment in the history of South African contract law was the emphatic interment of the exceptio doli generalis by Joubert JA in Bank of Lisbon and South Africa v De Ornelas 1988 (3) SA580 (A). Throughout most of the twentieth century, the exceptio doli generalis had been viewed as an equitable defence that allowed a defendant to resist a claim for performance under a contract when there was something unconscionable about the plaintiff's seeking to enforce the contract (or a clause thereof) in the specific circumstances of that case (see A J Kerr Principles of the Law of Contract 6 ed (2002) 637ff; P J Aronstam 'Unconscionable contracts: The South African solution?' (1979) 42 THRHR 21; P van Warmelo 'Exceptio doli' 1981 De Jure 202).
- Full Text: false
- Date Issued: 2007
The comparison of in vitro release methods for the evaluation of oxytocin release from Pluronic® F127 parenteral formulations
- Chaibva, Faith A, Walker, Roderick B
- Authors: Chaibva, Faith A , Walker, Roderick B
- Date: 2007
- Language: English
- Type: Article
- Identifier: vital:6351 , http://hdl.handle.net/10962/d1006033
- Description: The objective of these studies was to develop a discriminatory in vitro release test for assessing formulation factors that may affect oxytocin (OT) release during formulation development studies of a Pluronic® F127 OT in situ gel-forming parenteral dosage form. An appropriate release assessment method should be able to discriminate between the performance of different formulation compositions (1, 2), and this was the primary criterion used for selection of an appropriate test procedure during the test method development process. ANOVA and the difference (f1) and similarity (f2)factors were used to evaluate the discriminatory behavior of different test methods that were investigated in these studies. The in vitro release tests that were investigated included the use of USP Apparatus 1, 2, and 3; a dialysis bag in USP Apparatus 2; and a membrane-less diffusion method. It was concluded that the use of USP Apparatus 3 was best able to discriminate between OT release for the different formulations tested. USP Apparatus 3 was thus considered the most suitable in vitro release test apparatus for studying formulation factors affecting OT release during the development of a parenteral dosage form prepared using Pluronic® F127.
- Full Text:
- Date Issued: 2007
- Authors: Chaibva, Faith A , Walker, Roderick B
- Date: 2007
- Language: English
- Type: Article
- Identifier: vital:6351 , http://hdl.handle.net/10962/d1006033
- Description: The objective of these studies was to develop a discriminatory in vitro release test for assessing formulation factors that may affect oxytocin (OT) release during formulation development studies of a Pluronic® F127 OT in situ gel-forming parenteral dosage form. An appropriate release assessment method should be able to discriminate between the performance of different formulation compositions (1, 2), and this was the primary criterion used for selection of an appropriate test procedure during the test method development process. ANOVA and the difference (f1) and similarity (f2)factors were used to evaluate the discriminatory behavior of different test methods that were investigated in these studies. The in vitro release tests that were investigated included the use of USP Apparatus 1, 2, and 3; a dialysis bag in USP Apparatus 2; and a membrane-less diffusion method. It was concluded that the use of USP Apparatus 3 was best able to discriminate between OT release for the different formulations tested. USP Apparatus 3 was thus considered the most suitable in vitro release test apparatus for studying formulation factors affecting OT release during the development of a parenteral dosage form prepared using Pluronic® F127.
- Full Text:
- Date Issued: 2007
Determining the daily spawning cycle of the chokka squid, Loligo reynaudii off the South African Coast
- Authors: Melo, Y , Sauer, Warwick H H
- Date: 2007
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/124275 , vital:35588 , https://doi.10.1007/s11160-006-9034-6
- Description: The study investigated the duration and peak of the daily spawning cycle of the chokka squid Loligo reynaudii, and the possibility of estimating the spawning frequency by means of classification and grouping (by age) of postovulatory follicles. Post-ovulatory follicles were classified into three types: new, intermediate or old, based in part on the degree of resorption of the follicles determined from histological sections. Ovulation in this species appears to be a rapid process, seen by the occurrence of both mature oocytes and post-ovulatory follicles in partially spent ovaries. Results suggest that chokka squid present a diel timing of spawning, with successive periods of egg accumulation at night, interrupted by periods of active spawning during the day. The ovarian cycle for this species appears typical of serial spawners. During the spawning phase ovaries go through ripe, partially spent and recovering stages by undergoing a process of maturation, ovulation and redeveloping, where a new batch of advanced oocytes is recruited. The cycle typically appears to last between 24 and 36 h, and may depend on a number of factors such as environmental conditions and the presence of predators. The short-lived (about 14 h) nature of the post-ovulatory follicles precludes the calculation of the exact spawning interval and does not allow us to accurately predict the spawning frequency. Together with the degree of oviduct fullness they do however give a good indication of imminent or recent spawning.
- Full Text:
- Date Issued: 2007
- Authors: Melo, Y , Sauer, Warwick H H
- Date: 2007
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/124275 , vital:35588 , https://doi.10.1007/s11160-006-9034-6
- Description: The study investigated the duration and peak of the daily spawning cycle of the chokka squid Loligo reynaudii, and the possibility of estimating the spawning frequency by means of classification and grouping (by age) of postovulatory follicles. Post-ovulatory follicles were classified into three types: new, intermediate or old, based in part on the degree of resorption of the follicles determined from histological sections. Ovulation in this species appears to be a rapid process, seen by the occurrence of both mature oocytes and post-ovulatory follicles in partially spent ovaries. Results suggest that chokka squid present a diel timing of spawning, with successive periods of egg accumulation at night, interrupted by periods of active spawning during the day. The ovarian cycle for this species appears typical of serial spawners. During the spawning phase ovaries go through ripe, partially spent and recovering stages by undergoing a process of maturation, ovulation and redeveloping, where a new batch of advanced oocytes is recruited. The cycle typically appears to last between 24 and 36 h, and may depend on a number of factors such as environmental conditions and the presence of predators. The short-lived (about 14 h) nature of the post-ovulatory follicles precludes the calculation of the exact spawning interval and does not allow us to accurately predict the spawning frequency. Together with the degree of oviduct fullness they do however give a good indication of imminent or recent spawning.
- Full Text:
- Date Issued: 2007
Think Piece : an opening dialogue with Think Pieces and feature articles on learning in a changing world in this journal
- Authors: Lotz-Sisitka, Heila
- Date: 2007
- Language: English
- Type: article , text
- Identifier: http://hdl.handle.net/10962/59602 , vital:27630 , https://www.ajol.info/index.php/sajee/article/view/122734
- Description: From Conclusion:This opening Think Piece invites you into such a dialogue, with this journal, its words and flows of meaning, and with the World Environmental Education Congress, its words and flows of meaning. Dialogue, as explained by Bohm, and as illustrated in the thought experiments in this paper, is a process of creatively and experimentally seeking out meaning and coherence through listening, and through deeper explorations of the tacit, implicate order. It is also a free process, where you as individual are invited to seek out the relations between your thoughts and the collective. Welcome to the process.
- Full Text:
- Date Issued: 2007
- Authors: Lotz-Sisitka, Heila
- Date: 2007
- Language: English
- Type: article , text
- Identifier: http://hdl.handle.net/10962/59602 , vital:27630 , https://www.ajol.info/index.php/sajee/article/view/122734
- Description: From Conclusion:This opening Think Piece invites you into such a dialogue, with this journal, its words and flows of meaning, and with the World Environmental Education Congress, its words and flows of meaning. Dialogue, as explained by Bohm, and as illustrated in the thought experiments in this paper, is a process of creatively and experimentally seeking out meaning and coherence through listening, and through deeper explorations of the tacit, implicate order. It is also a free process, where you as individual are invited to seek out the relations between your thoughts and the collective. Welcome to the process.
- Full Text:
- Date Issued: 2007
Address at the opening of the OutRhodes Pride Week, 21 August 2007
- Authors: Badat, Saleem
- Date: 2007
- Subjects: Rhodes University
- Language: English
- Type: text
- Identifier: vital:7652 , http://hdl.handle.net/10962/d1015780
- Full Text:
- Date Issued: 2007
- Authors: Badat, Saleem
- Date: 2007
- Subjects: Rhodes University
- Language: English
- Type: text
- Identifier: vital:7652 , http://hdl.handle.net/10962/d1015780
- Full Text:
- Date Issued: 2007
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