List of Titles

Aminoacyl tRNA synthetases as malarial drug targets: a comparative bioinformatics study

- Nyamai, Dorothy Wavinya, Tastan Bishop, Özlem

Authors: Nyamai, Dorothy Wavinya , Tastan Bishop, Özlem
Date: 2018
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/148368 , vital:38733 , DOI: 10.1101/440891
Description: Treatment of parasitic diseases has been challenging due to evolution of drug resistant parasites, and thus there is need to identify new class of drugs and drug targets. Protein translation is important for survival of malarial parasite, Plasmodium, and the pathway is present in all of its life cycle stages. Aminoacyl tRNA synthetases are primary enzymes in protein translation as they catalyse amino acid addition to the cognate tRNA. This study sought to understand differences between Plasmodium and human aminoacyl tRNA synthetases through bioinformatics analysis.
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Date Issued: 2018

Expanding the SAR of Nontoxic Antiplasmodial Indolyl-3-ethanone Ethers and Thioethers:

- Lunga, Mayibongwe J, Chisango, Ruramai L, Weyers, Carli, Isaacs, Michelle, Taylor, Dale, Edkins, Adrienne L, Khanye, Setshaba D, Hoppe, Heinrich C, Veale, Clinton G L

Authors: Lunga, Mayibongwe J , Chisango, Ruramai L , Weyers, Carli , Isaacs, Michelle , Taylor, Dale , Edkins, Adrienne L , Khanye, Setshaba D , Hoppe, Heinrich C , Veale, Clinton G L
Date: 2018
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/164389 , vital:41114 , DOI: 10.1002/cmdc.201800235
Description: Despite major strides in reducing Plasmodium falciparum infections, this parasite still accounts for roughly half a million annual deaths. This problem is compounded by the decreased efficacy of artemisinin combination therapies. Therefore, the development and optimisation of novel antimalarial chemotypes is critical. In this study, we describe our strategic approach to optimise a class of previously reported antimalarials, resulting in the discovery of 1-(5-chloro-1H-indol-3-yl)-2-[(4-cyanophenyl)thio]ethanone (13) and 1-(5-chloro-1H-indol-3-yl)-2-[(4-nitrophenyl)thio]ethanone (14), whose activity was equipotent to that of chloroquine against the P. falciparum 3D7 strain.
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Date Issued: 2018

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Low symmetric metallophthalocyanine modified electrode via click chemistry for simultaneous detection of heavy metals

- Fomo, Gertrude, Nwaji, Njemuwa, Nyokong, Tebello

Authors: Fomo, Gertrude , Nwaji, Njemuwa , Nyokong, Tebello
Date: 2018
Subjects: To be catalogued
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/187914 , vital:44709 , xlink:href="https://doi.org/10.1016/j.jelechem.2018.02.016"
Description: Beside different methods and materials used to develop electrochemical sensors, the modification of the electrode using click reaction based on metallophthalocyanine (MPc) compounds are shown to improve the stability and sensitivity of the sensor. This work reported the development of electrochemical sensor for mercury (II), Lead (II), copper (II) and cadmium (II) ions detection based on the synthesized novel low symmetry alkyne terminated cobalt Phthalocyanine (CoPc) derivative. Differential pulse stripping voltammetry (DPSV) technique was employed for the first time in simultaneous determination of trace levels of the above metal ions using modified glassy carbon electrode (GCE) via click chemistry. Under the optimum experimental conditions, the anodic peak current is proportional to the concentrations of metal ions over a wide range of 0 to 0.1 mM with nanolevel detection limit of 81.94, 327.71, 55.87 and 347.06 nM and the sensitivity of 866.23 ± 5.48, 215.82 ± 2.16, 1979.48 ± 11.47 and 204.50 ± 1.10 μA/mM for Hg(II), Cu(II), Pb(II) and Cd(II), respectively. The selectivity of the clicked-CoPc modified GCE toward Hg(II), Cu(II), Pb(II), Cd(II) present no interference from these metals ions. The fabricated electrochemical sensor exhibited very good electrochemical properties such as good reproducibility, stability, reusability and is suitable for the detection of heavy metal ions in tap water in our laboratory.
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Date Issued: 2018

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The use of experimental design for the development and validation of an HPLC-ECD method for the quantitation of efavirenz

- Makoni, Pedzisai A, Khamanga, Sandile M, Kasongo, Kasongo W, Walker, Roderick B

Authors: Makoni, Pedzisai A , Khamanga, Sandile M , Kasongo, Kasongo W , Walker, Roderick B
Date: 2018
Subjects: To be catalogued
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/183556 , vital:44006 , xlink:href="https://doi.org/10.1691/ph.2018.8074"
Description: A high performance liquid chromatography with electrochemical detection (HPLC-ECD) method for the quantitation of efavirenz (EFV) was developed, since traditional HPLC-UV methods may be inappropriate, given that EFV undergoes photolytic degradation following exposure to UV light. This work describes the use of response surface methodology (RSM) based on a central composite design (CCD) to develop a stability-indicating HPLC method with pulsed ECD in direct current (DC) mode at an applied potential difference and current of +1400 mV and 1.0 μA for the analysis of EFV. Separation of EFV and imipramine was achieved using a Nova-Pak®C18 cartridge column and a mobile phase of phosphate buffer (pH 4.5): acetonitrile (ACN) (55:45 v/v). Mobile phase pH, buffer molarity, ACN concentration and applied potential difference were investigated. The optimized method produced sharp well resolved peaks for imipramine and EFV with retention times of 3.70 and 8.89 minutes. The calibration curve was linear (R2 = 0.9979) over the range 5-70 μg/mL. Repeatability and intermediate precision ranged between 3.37 and 4.34 % RSD and 1.31 and 4.29 % RSD and accuracy between -0.80 and 4.71 % bias. The LOQ and LOD were 5.0 and 1.5 μg/mL. The method was specific for EFV and was used to analyse EFV in commercially available tablets. The HPLC-ECD method is more suitable for quantitative analysis of EFV than HPLC-UV.
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Date Issued: 2018

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The relation between galaxy density and radio jet power for 1.4 GHz VLA selected AGNs in Stripe 82

- Kolwa, S, Jarvis, M J, McAlpine, Kim, Heywood, Ian

Authors: Kolwa, S , Jarvis, M J , McAlpine, Kim , Heywood, Ian
Date: 2018
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/131444 , vital:36572 , https://doi.org/10.1093/mnras/sty3019
Description: Using a Karl G. Jansky Very Large Array (VLA) L-band (1-2 GHz) survey covering ∼100 deg2 of the Stripe 82 field, we have obtained a catalogue of 2716 radio AGNs. For these AGNs, we investigate the impact of galaxy density on 1.4 GHz radio luminosity (L1.4). We determine their close environment densities using the surface density parameter, ΣN, for N = 2 and N = 5, which we bin by redshift to obtain a pseudo-3D galaxy density measure. Matching the radio AGNs to sources without radio detections in terms of redshift, K-band magnitude and (g − K) colour index, we obtain samples of control galaxies and determine whether radio AGN environments differ from this general population.
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Date Issued: 2018

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The Primary Demonstration of Exciton Coupling Effects on Optical Limiting Properties of Blue Double-Decker Lanthanide Phthalocyanine Salts

- Sekhosana, Kutloano E, Nkhahle, Reitumetse, Nyokong, Tebello

Authors: Sekhosana, Kutloano E , Nkhahle, Reitumetse , Nyokong, Tebello
Date: 2018
Subjects: To be catalogued
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/234614 , vital:50213 , xlink:href="https://doi.org/10.1002/slct.201800597"
Description: In this manuscript, novel green and blue sandwich-type rare-earth phthalocyanines (LnPc2) are presented. This parent green LnPc2 complex is named bis-{2(3),9(10),16(17),23(24)-tetra(4-tert-buylphenoxy) phthalocyaninato} neodymium (III) (2) and modified into blue LnPc2 complexes (3), (4) and (5) based on hexadecyltrimethylammonium ion, mononeodymium(III) diacetate and monodysprosium(III) diacetate as counter ions, respectively. These stable blue lanthanide Pc salts are highly soluble in many organic and inorganic solvents. All complexes 2, 3, 4 and 5 were studied for optical limiting for the first time using Z-scan at nanosecond regime in the visible absorption spectral wavelength (532 nm). Our studies reveal the advantage of exciton coupling in blue sandwich-type rare-earth phthalocyanines over the π-radicals (characterized by blue valence at 485 nm) in the green counterpart which are in resonance with the 532 nm wavelength for optical limiting application. Large singlet ground state to excited state absorption cross section ratios were found, particularly for complex 5 in comparison to that of complex 2.
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Date Issued: 2018

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Urban street names: An opportunity to examine biocultural relationships?

- Shackleton, Charlie M

Authors: Shackleton, Charlie M
Date: 2018
Subjects: To be catalogued
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/182285 , vital:43817 , xlink:href="https://doi.org/10.1371/journal.pone.0200891"
Description: With increasing urbanisation there is concern regarding loss of experience and knowledge of biodiversity amongst urban populations. Yet biodiversity representations are retained in many art and functional forms, including names of places, buildings, institutions and streets. These manifestations offer a window to examine the relationship between humans and their experienced or imagined environment using a biocultural lens. I quantified the current prevalence of urban streets named after animals or plant species, the diversity of species represented, whether they are native or non-native, whether representative of the biome in which the town was situated and the change in prevalence through time. The street names of 48 towns in a one degree wide south-north belt across seven of South African’s biomes were captured and analysed. Of the 4,359 street names, 11.1% were named after plants (218 species) and 5.3% after animals (131 species), although some towns had none and others more than 40%. Approximately half of the plants were native to South Africa, whereas over 80% of the animals were. There was no correspondence between the species composition reflected in street names and the biome in which towns were located. The proportion of streets named after plants or animals has generally increased over the last two hundred years. These results provide insights into the bioculturally defined plants and animals that are valued by past and present urban communities, showing that they are generally from a wider array than can be found or experienced in the local setting.
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Date Issued: 2018

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Allosteric Modulation of Human Hsp90α Conformational Dynamics:

- Penkler, David L, Atilgan, Canan, Tastan Bishop, Özlem

Authors: Penkler, David L , Atilgan, Canan , Tastan Bishop, Özlem
Date: 2018
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/162936 , vital:40998 , https://doi.org/10.1021/acs.jcim.7b00630
Description: Central to Hsp90’s biological function is its ability to interconvert between various conformational states. Drug targeting of Hsp90’s regulatory mechanisms, including its modulation by cochaperone association, presents as an attractive therapeutic strategy for Hsp90 associated pathologies. In this study, we utilized homology modeling techniques to calculate full-length structures of human Hsp90α in closed and partially open conformations and used these structures as a basis for several molecular dynamics based analyses aimed at elucidating allosteric mechanisms and modulation sites in human Hsp90α.
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Date Issued: 2018

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Synthesis, antiplasmodial and antitrypanosomal evaluation of a series of novel 2-oxoquinoline-based thiosemicarbazone derivatives

- Darrell, Oliver T, Hulushe, Siyabonga T, Mtshare, Thanduxolo Elihle, Beteck, Richard M, Isaacs, Michelle, Laming, Dustin, Khanye, Setshaba D, Hoppe, Heinrich C, Krause, Rui W M

Authors: Darrell, Oliver T , Hulushe, Siyabonga T , Mtshare, Thanduxolo Elihle , Beteck, Richard M , Isaacs, Michelle , Laming, Dustin , Khanye, Setshaba D , Hoppe, Heinrich C , Krause, Rui W M
Date: 2018
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/123117 , vital:35407 , https://doi.org/10.17159/0379-4350/2018/v71a25
Description: Herein a series of novel thiosemicarbazones (TSCs) derived from 2-oxoquinoline scaffold is reported, and the target compounds have been successfully synthesized and characterized using standard spectroscopic techniques. The in vitro biological activities of synthesized molecules were evaluated against Plasmodium falciparum malaria parasites (strain 3D7), Trypanosoma brucei brucei parasites (strain 427) and HeLa cells. All the compounds displayed modest or no activity at a concentration of 20 μM and percentage viability of >50 % was often observed. Except for compound 9o, none of the final compounds exhibited cytotoxic effects against HeLa cells at 20 μM.
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Date Issued: 2018

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LRP1 is required for novobiocin-mediated fibronectin turnover:

- Boel, Natasha M-E, Hunter, Morgan C, Edkins, Adrienne L

Authors: Boel, Natasha M-E , Hunter, Morgan C , Edkins, Adrienne L
Date: 2018
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/164896 , vital:41182 , DOI: 10.1038/s41598-018-29531-2
Description: Fibronectin (FN) plays a major role in the stability and organization of the extracellular matrix (ECM). We have previously demonstrated that FN interacts directly with Hsp90, as well as showing that the Hsp90 inhibitor novobiocin results in FN turnover via a receptor mediated process. However, the receptor involved has not been previously identified. LRP1 is a ubiquitous receptor responsible for the internalisation of numerous ligands that binds both Hsp90 and FN, and therefore we investigated whether LRP1 was involved in novobiocin-mediated FN turnover.
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Date Issued: 2018

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A gold–chitosan composite with low symmetry zinc phthalocyanine for enhanced singlet oxygen generation and improved photodynamic therapy activity

- Dube, Edith, Oluwole, David O, Prinsloo, Earl, Nyokong, Tebello

Authors: Dube, Edith , Oluwole, David O , Prinsloo, Earl , Nyokong, Tebello
Date: 2018
Subjects: To be catalogued
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/233397 , vital:50087 , xlink:href="https://doi.org/10.1039/C8NJ00801A"
Description: Novel zinc(II) 3-(4-((3,17,23-tris(4-(benzo[d]thiazol-2-yl)phenoxy)phthalocyanine-9-yl)oxy)phenyl)propanoic acid (complex 3) was synthesised. Complex 3 was subsequently reacted with gold nanoparticles (AuNPs), chitosan (CT) and a gold–chitosan (AuCT) hybrid to form 3-AuNPs, 3-CT and 3-AuCT, respectively. The conjugates afforded a decrease in fluorescence quantum yield with a corresponding increase in the triplet and singlet quantum yields compared to complex 3. The in vitro dark cytotoxicity and photodynamic therapy activity (PDT) of complex 3 and 3-AuCT composites were investigated against epithelial breast cancer cells (MCF-7) with both the samples showing minimum dark cytotoxicity. They both accounted for a cell viability of ≥90% at a concentration of ≤59.2 μg mL−1. 3-AuCT showed better PDT activity (compared to 3 alone) with less than 50% viable cells at a concentration of ≥29.6 μg mL−1 making it potentially applicable for PDT. On the other hand, AuCT displayed some activity against cancer cells, probably due to photothermal activity since gold is a light absorber, however it had more than 50% viable cells at a concentration of ≤59.2 μg mL−1.
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Date Issued: 2018

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Kowieria alveoformis gen. nov. sp. nov., a new heterosporous lycophyte from the Latest Devonian of Southern Africa

- Gess, Robert W, Prestianni, Cyrille

Authors: Gess, Robert W , Prestianni, Cyrille
Date: 2018
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/73894 , vital:30239 , https://doi.org/10.1016/j.revpalbo.2017.10.002
Description: A new lycopsid, Kowieria alveoformis gen. et sp. nov., is described from the FamennianWitpoort Formation, Grahamstown, South Africa. It possesses spirally arranged elongated falcate vegetative leaves. Terminal bisporangiate strobili are present and show loosely grouped micro- and megasporophylls. Sporophylls are similar in shape to the vegetative leaves though somewhat wider with a marked expansion to house the sporangium. One sporangium is attached directly to the adaxial surface of the lamina. Each megasporangium contains up to four heavily ornamented hologulate megaspores of the Lagenicula type. The combination of both basal and derived characters within this plant places it at an interesting position at the base of the phylogenetic tree of rhizomorphic lycopsids.
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Date Issued: 2018

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Effects of the carboxylic acid substituents on the photophysical and nonlinear optical properties of asymmetrical Zn (II) phthalocyanines–quantum dots conjugates

- Mgidlana, Sithi, Oluwole, David O, Nyokong, Tebello

Authors: Mgidlana, Sithi , Oluwole, David O , Nyokong, Tebello
Date: 2018
Subjects: To be catalogued
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/187662 , vital:44684 , xlink:href="https://doi.org/10.1080/24701556.2018.1503684"
Description: This work reports on three asymmetrical Zn(II) phthalocyanines, namely: zinc(II) 3–(4-phenoxy)propanoic acid) phthalocyanine(1), zinc(II) 3–(4-phenoxy carboxylic acid) phthalocyanine (2) and zinc(II) 3–(4–oxy)phenoxy)acetic acid phthalocyanine (3) when covalently linked to glutathione(GSH) capped CdTe/ZnSe and CdTe/ZnSe/ZnO quantum dots (QDs). Of the Pc complexes alone, 1 afforded the highest triplet quantum yield (ΦT) value of 0.67 with corresponding largest nonlinear absorption coefficient (βeff) value of 14.0 cm/GW compared to 2 and 3. The conjugates afforded improved triplet quantum yield and nonlinear optical behavior in comparison to the Pc complexes alone.
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Date Issued: 2018

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Social-ecological systems as complex adaptive systems

- Preiser, Rika, Biggs, Reinette, de Vos, Alta, Folke, Carl

Authors: Preiser, Rika , Biggs, Reinette , de Vos, Alta , Folke, Carl
Date: 2018
Subjects: To be catalogued
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/416410 , vital:71346 , xlink:href="https://doi.org/10.5751/ES-10558-230446"
Description: The study of social-ecological systems (SES) has been significantly shaped by insights from research on complex adaptive systems (CAS). We offer a brief overview of the conceptual integration of CAS research and its implications for the advancement of SES studies and methods. We propose a conceptual typology of six organizing principles of CAS based on a comparison of leading scholars’ classifications of CAS features and properties. This typology clusters together similar underlying organizing principles of the features and attributes of CAS, and serves as a heuristic framework for identifying methods and approaches that account for the key features of SES. These principles can help identify appropriate methods and approaches for studying SES. We discuss three main implications of studying and engaging with SES as CAS. First, there needs to be a shift in focus when studying the dynamics and interactions in SES, to better capture the nature of the organizing principles that characterize SES behavior. Second, realizing that the nature of the intertwined social-ecological relations is complex has real consequences for how we choose methods and practical approaches for observing and studying SES interactions. Third, engagement with SES as CAS poses normative challenges for problemoriented researchers and practitioners taking on real-world challenges.
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Date Issued: 2018

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Revolutionary trends at the National Arts Festival 2017 (an overview)

- Krueger, Anton

Authors: Krueger, Anton
Date: 2018
Subjects: To be catalogued
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/225563 , vital:49235 , xlink:href="https://doi.org/10.1080/10137548.2017.1407025"
Description: My 2017 Fest Everybody's festival is different. Each individual charts their own course in navigating this vast, unwieldy, multidisciplinary festival of festivals that happens every year in the Eastern Cape. Since the long running print version of the festival paper, Cue went under this year when Standard Bank withdrew funding, I wasn't officially reviewing and this freed me up to play a bit more and to see things that appealed to me, rather than having to attend shows from a sense of obligation.
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Date Issued: 2018

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Evaluating the effects of catch-and-release angling on Cape stumpnose Rhabdosargus holubi in a South African estuary

- Arkert, N K, Childs, Amber-Robyn, Parkinson, Matthew C, Winkler, Alexander C, Butler, Edward C, Mannheim, Samantha L, Potts, Warren M

Authors: Arkert, N K , Childs, Amber-Robyn , Parkinson, Matthew C , Winkler, Alexander C , Butler, Edward C , Mannheim, Samantha L , Potts, Warren M
Date: 2018
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/124439 , vital:35613 , https://doi.10.2989/1814232x.2018.1494041
Description: Fisheries managers are increasingly promoting catch and release (C&R) as a means to manage recreational fish stocks. Several commonly used output regulations, including bag and size limits, require the mandatory release of captured fishes by anglers. In addition to mandatory C&R, conservation-conscious anglers have adopted voluntary C&R behaviour as a result of the noticeable declines in the populations of many fishery species and this behaviour is becoming increasingly popular among recreational anglers (Cooke et al. 2013a). The combination of mandatory and voluntary C&R behaviour is substantial, as Raby et al. (2014) estimated that 60% of fish captured in global recreational fisheries are released. In South Africa, Cowley et al. (2013) found that a large proportion (mean 74% [SD 7.3]) of the five most-dominant fishery species captured in the Sundays Estuary recreational fishery were released.
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Date Issued: 2018

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Genomic analysis reveals multiple mismatches between biological and management units in yellowfin tuna (Thunnus albacares)

- Mullins, Rachel B, McKeown, Niall J, Sauer, Warwick H H, Shaw, Paul W

Authors: Mullins, Rachel B , McKeown, Niall J , Sauer, Warwick H H , Shaw, Paul W
Date: 2018
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/124549 , vital:35627 , https://doi.10.1093/icesjms/fsy102
Description: The South African (SAF) yellowfin tuna (Thunnus albacares) fishery represents a potential example of misalignment between management units and biological processes. The SAF fishery spans an operational stock with a boundary at 20_E, either side of which fish are considered part of Atlantic or Indian Ocean regional stocks. However, the actual recruitment of fish from Atlantic and Indian Ocean spawning populations into SAF waters is unknown. To address this knowledge gap, genomic analysis (11 101 SNPs) was performed on samples from Atlantic and Indian Ocean spawning sites, including SAF sites spanning the current stock boundary. Outlier loci conferred high discriminatory power to assignment tests and revealed that all SAF fish were assigned to the Indian Ocean population and that no Atlantic Ocean fish appeared in the SAF samples. Additionally, several Indian Ocean migrants were detected at the Atlantic spawning site demonstrating asymmetric dispersal and the occurrence of a mixed-stock fishery in Atlantic waters. This study highlights both the spatial inaccuracy of current stock designations and a misunderstanding of interactions between the underlying biological units, which must be addressed in light of local and global declines of the species. Specifically, the entire SAF fishery must be managed as part of the Indian Ocean stock.
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Date Issued: 2018

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This is our story: iconography of carved doors and panels in Òyó Palace

- Fọlárànmí, Stephen

Authors: Fọlárànmí, Stephen
Date: 2018
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/145698 , vital:38459 , https://0-doi.org.wam.seals.ac.za/10.1162/afar_a_00402
Description: This saying or prayer is one of the numerous expressions among the Yorùbá about the door and its significance, not only as a physical and important aspect of their architecture, but also in their language and culture. It also alludes to its pride of place as perhaps the most decorated element of Yorùbá architecture. From private homes, to the homes of the rich, shrines, and palaces, Yorùbá doors are usually imbued with a considerable array of images and icons that proclaims the owner's identity, religion, occupation. The Yorùbá are not unique in this respect. For example, among the Dogon, the door is as important as the house on which it is affixed. The granary, according to Willett (2002: 176), protects the the food stored inside it, while the door is seen or referred to as an element not only for physical protection, but also as a spiritual means of warding off unwanted spirits. It is reasonable, therefore, to expect the door to receive aesthetic attention by embellishment with an array of images.
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Date Issued: 2018

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Art topples monuments: artistic practice and colonial/postcolonial relations in the public space of Luanda

- Siegert, Nadine

Authors: Siegert, Nadine
Date: 2018
Language: English
Type: text , article
Identifier: http://hdl.handle.net/10962/147014 , vital:38585
Description: Even though there have been very few modern and contemporary artworks in the urban space of Luanda in the years after independence in 1975—and especially after the end of the civil war in 2002—there are two works by Angolan artists that are of particular interest: the sculpture Mitologias II (1984) by António Ole (b. 1951) and the photographic series Redefining the Power (2011) by Kiluanji Kia Henda (b. 1978). Both works address the possibility of using contemporary art as a symbolic form of the replacement of power, since both are built on pedestals that had previously supported monuments of Portuguese colonial power. They might, therefore, be read as a form of substitution for monuments that would commemorate and celebrate independence or the end of colonialism. This article also discusses whether these two artworks can also be regarded as counter-monuments and this contributes to the discourse on the visual and material culture of Lusophone Africa.
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Date Issued: 2018

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