http://vital.seals.ac.za:8080/vital/access/manager/Index ${session.getAttribute("locale")} 5 http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:59356 Wed 30 Nov 2022 15:05:41 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:59302 Wed 30 Nov 2022 13:41:41 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:42970 30.01 µg/l). The most important factors associated with iron deficiency anaemia in all pregnant women were geophagic behaviour (OR=2.1 95% CI 1.1-4.2; P=0.029), MCHC decreases (<30.5 0R=16.6 95%CI 6.8-40.2; P=0.006) and MCHC decreases (30.5-31.5 OR=2.9 95%CI 1.4-6.1; P=0.006). In all pregnant women, serum iron <14 (OR=6.2 95%CI 1.2-31.7; P=0.030), platelets <228 (OR=3.9 95%CI 1.6-10.8; P=0.008), age ≥28years (OR=4.2 95%CI 1.7-10.4; P=0.002), transferrin saturation ≥18% (OR=51.3 95%CI 8.9-295.2; P=<0.0001), were identified as the most significant independent determinants of ferritin-related oxidative stress. However, increase in age, depletion in iron, decrease in platelet count but increase in transferrin saturation were the significant independent determinants of ferritin-related oxidative stress among geophagic pregnant women (Y=0.282 x Age – 1.007 x iron – 0.023 platelet +0.946 transferrin saturation). In non-geophagic pregnant women, only a decrease in iron and an increase in transferrin saturation were the significant characteristics of ferritin-related oxidative stress (Y=-3.21-0.309 x iron + 0.379 transferrin saturation). Conclusioniii Geophagia induces a high level of anaemia, iron deficiency anaemia and ferritin-related oxidative stress. The most independent determinants of iron deficiency anaemia in all pregnant women were geophagic behaviour and MCHC decrease. Independent and important determinants of ferritin-related oxidative stress in all pregnant women were severe categories of decreased iron and platelets with higher levels of age ≥28 years, transferrin saturation (≥18%)]]> Wed 28 Apr 2021 18:22:18 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:42964 3 groups. Chi – square test was used to compare proportions between 2 groups. Multivariate (multiple linear regression, binary logistic regression, and discriminant functions) analyses were used to identify the most important risk factors of all strokes and fibrinogen to discriminate stroke types and subtypes. ROC method obtained specific ethnic cut–off points of biomarkers that associated independently with all strokes. In total 67 participants were examined: 37 cases of strokes (11 ischemic, 26 haemorrhagic, 11 lacunar ischemic, 13 intra-cerebral hematomas and 8 haemorrhagic brain ischaemia) versus 28 controls. Low socio – economic status (OR=10.3 95%CI 3.3- 32.9 p<0.0001), physical inactivity (OR=13 95% CI 3.3-51.6 p<0.0001), rural residence(OR=6.5 95% CI 1.6-26.5 p=0.004), RDW(OR=3.7 95% CI 1.3-10.9 p=0.016), D – dimer (OR=17.4 95% CI 2.9-104 p=0.002), Fibrinogen (OR=35.1 95% CI 3.5-356.5 p=0.003), and BMI(OR=1.387 95% CI 0.985-2 p=0.06) were the most independent risk factors of all strokes. RDW, Platelets, D-dimer, and Neutrophils were the most discriminant of absence of strokes, ischaemic and haemorrhagic types of stroke. Only Fibrinogen and BNP were the most discriminant of stroke subtypes in low socio–economic status. Meanwhile, Platelets, Neutrophils, and CRP were the most discriminant of stroke subtypes in high socio – economic status. The cut-off points of RDW>14%, Fibrinogen>3.5 g/L, and D-dimer>0.5g/mL separated efficiently all stroke types and controls. Independent variations (R2 = 48%) of Fibrinogen in all participants were explained by increase in CRP (Beta = 0.315; P = 0.003), Platelets (Beta = 0.280; P = 0.004), BMI (Beta = 0.268; P = 0.006), and Monocytes (Beta = 0.241; P = 0.014).iii In conclusion, increased levels of Biomarkers of inflammation, thrombosis, hypercoagulability, but opposite variations of innate immunity (increase in monocytes, decrease or increase in neutrophils), overweight/Obesity, low socio-economic status, physical inactivity, and rural residence were the major risk factors of all strokes. Biomarkers of inflammation have superior performance to diagnose all strokes and to discriminate stroke types and to predict the severity of stroke subtypes than the few traditional cardiovascular risk factors. Education, adequate diet, exercise, reduction of poverty, other measures of secondary prevention, applied research, and integration of chemical pathology in the management of strokes are needed in personalised medicine with cheap tools (RDW, platelets and Fibrinogen) in absence of neuro – imaging in the poorest Eastern Cape province of South Africa.]]> Wed 28 Apr 2021 16:58:18 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:42866 Wed 23 Feb 2022 15:49:49 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:52352 Wed 22 Jun 2022 14:44:43 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:51017 Wed 22 Jun 2022 14:09:44 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:51018 Wed 22 Jun 2022 13:41:44 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:42868 Wed 21 Apr 2021 17:33:33 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:42860 Wed 21 Apr 2021 16:44:33 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:42858 Wed 21 Apr 2021 16:30:27 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:42857 Wed 21 Apr 2021 16:02:39 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:42848 Wed 21 Apr 2021 14:59:37 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:32259 Wed 12 May 2021 23:44:46 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:30800 Wed 12 May 2021 23:42:58 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:32262 Wed 12 May 2021 23:33:58 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:30051 Wed 12 May 2021 23:25:55 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:27278 Wed 12 May 2021 23:19:05 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:29936 Wed 12 May 2021 23:00:15 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:35587 Wed 12 May 2021 22:47:58 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:27770 Wed 12 May 2021 22:17:31 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:27767 Wed 12 May 2021 20:18:39 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:30434 Wed 12 May 2021 19:00:57 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:35973 Wed 12 May 2021 17:23:12 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:30049 Wed 12 May 2021 17:10:37 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:30009 Wed 12 May 2021 17:09:49 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:27277 Wed 12 May 2021 17:09:08 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:32263 Wed 12 May 2021 16:40:22 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:34373 Wed 12 May 2021 16:09:22 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:27279 Wed 12 May 2021 16:01:09 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:35976 Wed 12 May 2021 15:43:42 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:38829 Wed 10 Jun 2020 20:01:53 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:43198 cysteine > PST > MPA when CdCl2 was used as cadmium precursor. When different cadmium precursors were used for L-cysteine, the particle sizes range from 2.06 – 2.31 nm for Cd(CH3COO)2 and 2.00 – 2.37 nm for Cd(NO3)2 while the intensity increased as the reaction time increased, however, still lower than the CdCl2 materials. The effect of Au ratio showed that the intensity of Au-doped cysteine capped-CdSe increased as the Au ratio decreased. The systematic study of the effect of temperature and growth time in the organic soluble CdSe nanoparticles on the size, optical and structural properties was also investigated. All the as-synthesised particles were blue-shifted in relation to the bulk CdSe. As the temperature increased the particle sizes of the undoped materials range between 2.92 – 2.95 nm at 160 °C and 5.35 – 5.39 nm at 200 °C while for the doped materials the particle size range from 2.53 – 2.61 nm at 160 °C, 3.97 nm at 200 °C and 4.20 – 4.72 nm at 240 °C. The intensity of the doped materials increased as the reaction time increased and then decreased again towards the end of the reaction. After ligand exchange the intensity of the as-synthesized doped and undoped-CdSe NPs was very low compare to the parent organically capped doped and un-doped CdSe. It was discovered that without any further purification, the quality of the materials formed by this method is comparable to that of the best CdSe NPs reported in the literature. This method is safe, inexpensive and reproducible.]]> Tue 15 Jun 2021 16:25:34 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:46340 Tue 08 Feb 2022 15:33:41 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:46285 Tue 08 Feb 2022 14:16:34 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:41453 Tue 08 Dec 2020 17:12:05 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:41452 Tue 08 Dec 2020 15:20:05 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:44600 Tue 05 Oct 2021 11:56:57 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:41455 Tue 05 Mar 2024 12:00:24 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:47200 Tue 01 Mar 2022 15:12:37 SAST ]]> http://vital.seals.ac.za:8080/vital/access/manager/Repository/vital:43340 Thu 29 Feb 2024 13:48:57 SAST ]]> 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