The PINIT domain of PIAS3: structure-function analysis of its interaction with STAT3

Title: The PINIT domain of PIAS3: structure-function analysis of its interaction with STAT3
Creator: Mautsa, Nicodemus
Creator: Prinsloo, Earl
Creator: Tastan Bishop, Özlem
Creator: Blatch, Gregory L
Date Issued: 2011
Date: 2011
Type: text
Type: article
Identifier: http://hdl.handle.net/10962/148082
Identifier: vital:38708
Identifier: DOI: 10.1002/jmr.1111
Description: The protein inhibitor of activated signal transducer and activator of transcription 3 (PIAS3) regulates the transcriptional activity of signal transducer and activator of transcription 3 (STAT3) which regulates transcription of genes involved in cell growth, proliferation and apoptosis. The conserved proline, isoleucine, asparagine, isoleucine, threonine (PINIT) domain of PIAS3 is thought to promote STAT3–PIAS3 interaction.
Format: 9 pages
Format: pdf
Language: English
Relation: Journal of Molecular Recognition
Relation: Mautsa, N., Prinsloo, E., Bishop, Ö.T. and Blatch, G.L., 2011. The PINIT domain of PIAS3: structure‐function analysis of its interaction with STAT3. Journal of Molecular Recognition, 24(5), pp.795-803.
Relation: Journal of Molecular Recognition volume 24 number 5 795 803 June 2011 1099-1352
Rights: Publisher
Rights: Use of this resource is governed by the terms and conditions of the Wiley Online Library Terms of Use statement (https://onlinelibrary.wiley.com/terms-and-conditions)

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Prinsloo, Earl (Dr)

Tastan Bishop, Ozlem (Prof)

Blatch, Gregory Lloyd (Prof)

RU Research Unit in Bioinformatics (RUBi)

RU Department of Biochemistry, Microbiology and Bioinformatics

SDG 09. Industry, Innovation and Infrastructure

SDG 03. Good Health and Well-Being

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