- Title
- PRIMO: an interactive homology modeling pipeline
- Creator
- Hatherley, Rowan
- Creator
- Brown, David K
- Creator
- Glenister, Michael
- Creator
- Tastan Bishop, Özlem
- Date Issued
- 2017
- Date
- 2017
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/148282
- Identifier
- vital:38726
- Identifier
- doi: 10.1371/journal.pone.0166698
- Description
- The development of automated servers to predict the three-dimensional structure of proteins has seen much progress over the years. These servers make calculations simpler, but largely exclude users from the process. In this study, we present the PRotein Interactive MOdeling (PRIMO) pipeline for homology modeling of protein monomers. The pipeline eases the multi-step modeling process, and reduces the workload required by the user, while still allowing engagement from the user during every step. Default parameters are given for each step, which can either be modified or supplemented with additional external input. PRIMO has been designed for users of varying levels of experience with homology modeling. The pipeline incorporates a user-friendly interface that makes it easy to alter parameters used during modeling.
- Format
- 21 pages
- Format
- Language
- English
- Relation
- PLoS One
- Relation
- Hatherley, R., Brown, D.K., Glenister, M. and Bishop, Ö.T., 2016. PRIMO: an interactive homology modeling pipeline. PLoS One, 11(11).
- Relation
- PLoS One volume 11 number 11 2017 1932-6203
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the PLoS One Open Access Statement (http://journals.plos.org/plosone/s/journal-information)
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Tastan Bishop, Ozlem (Prof)
RU Research Unit in Bioinformatics (RUBi)
RU Department of Biochemistry, Microbiology and Biotechnology
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | SOURCE1 | PRIMO.pdf | 2 MB | Adobe Acrobat PDF | View Details Download |