- Title
- Enhanced photodynamic antimicrobial activity of surface modified SiNPs doped with zinc (II) phthalocyanines: the effect of antimicrobial ampicillin and extra charges from a sultone
- Creator
- Magadla, Aviwe
- Creator
- Nyokong, Tebello
- Date Issued
- 2020
- Date
- 2020
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/160511
- Identifier
- vital:40452
- Identifier
- https://doi.org/10.1016/j.pdpdt.2020.101996
- Description
- 1-(2-Methoxyethyl)piperidine sustituted Zn phthalocyanine complex (2) is synthesised and quartenised (3). These complexes are loaded into silica nanoparticles (SiNPs) that are futher surface modified with ampicillin and 1.3-propanesultone. The photophysical and photochemical properties of the complexes and their doped conjugates were investigated in dimethylsulfoxide. The cationic complex (3) is used for photodynamic antimicrobial activity. Log reduction values of above 9 are obtained towards the photoiactivation of Staphyloccocus aureus.
- Format
- 12 pages
- Format
- Language
- English
- Relation
- Photodiagnosis and Photodynamic Therapy
- Relation
- Magadla, A. and Nyokong, T., 2020. Enhanced photodynamic antimicrobial activity of surface modified SiNPs doped with zinc (II) phthalocyanines: the effect of antimicrobial ampicillin and extra charges from a sultone. Photodiagnosis and Photodynamic Therapy, 32. p.101996
- Relation
- Photodiagnosis and Photodynamic Therapy volume 32 number p.10996 December 2020 1572-1000
- Rights
- Publishers
- Rights
- Use of this resource is governed by the terms and conditions of the Elsevier Terms and Conditions Statement (https://www.elsevier.com/legal/elsevier-website-terms-and-conditions)
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Collections
RU DST/NRF SARChI for Medicinal Chemistry and Nanotechnology
Nyokong, Tebello (Distinguished Professor)
RU Department of Chemistry
SDG 03. Good Health and Well-Being
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