Assessment of potential anti-cancer stem cell activity of marine algal compounds using an in vitro mammosphere assay:

de la Mare, Jo-Anne; Sterrenberg, Jason N; Sukhthankar, Mugdha G; Chiwakata, Maynard T; Beukes, Denzil R; Blatch, Gregory L; Edkins, Adrienne L

Title: Assessment of potential anti-cancer stem cell activity of marine algal compounds using an in vitro mammosphere assay:
Creator: de la Mare, Jo-Anne
Creator: Sterrenberg, Jason N
Creator: Sukhthankar, Mugdha G
Creator: Chiwakata, Maynard T
Creator: Beukes, Denzil R
Creator: Blatch, Gregory L
Creator: Edkins, Adrienne L
Date Issued: 2013
Date: 2013
Type: text
Type: article
Identifier: http://hdl.handle.net/10962/165184
Identifier: vital:41216
Identifier: DOI: 10.1186/1475-2867-13-39
Description: The cancer stem cell (CSC) theory proposes that tumours arise from and are sustained by a subpopulation of cells with both cancer and stem cell properties. One of the key hallmarks of CSCs is the ability to grow anchorage-independently under serum-free culture conditions resulting in the formation of tumourspheres. It has further been reported that these cells are resistant to traditional chemotherapeutic agents.
Format: 15 pages
Format: pdf
Language: English
Relation: Cancer cell international
Relation: de la Mare, J.A., Sterrenberg, J.N., Sukhthankar, M.G., Chiwakata, M.T., Beukes, D.R., Blatch, G.L. and Edkins, A.L., 2013. Assessment of potential anti-cancer stem cell activity of marine algal compounds using an in vitro mammosphere assay. Cancer cell international, 13(1), pp.1-14
Relation: Cancer cell international volume 13 number 1 1 14 May 2013 1475-2867
Rights: Publisher
Rights: Use of this resource is governed by the terms and conditions of the SpringerNature Statement (https://www.biomedcentral.com/)

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RU Department of Biochemistry, Microbiology and Biotechnology

Beukes, Denzil Ronwynne (Prof)

De la Mare, Jo-Anne (Dr)

Blatch, Gregory Lloyd (Prof)

RU Department of Pharmacy

Edkins, Adrienne Lesley (Associate Prof)

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