- Title
- Ruthenium complexes with mono-or bis-heterocyclic chelates: DNA/BSA binding, Antioxidant and Anticancer studies
- Creator
- Maikoo, Sanam
- Creator
- Chakraborty, Abir
- Creator
- Vukea, Nyeleti
- Creator
- Dingle, Laura M K
- Creator
- Samson, William J
- Creator
- de la Mare, Jo-Anne
- Creator
- Edkins, Adrienne L
- Creator
- Booysen, Irvin N
- Date Issued
- 2020
- Date
- 2020
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/165463
- Identifier
- vital:41246
- Identifier
- DOI: 10.1080/07391102.2020.1775126
- Description
- Deoxyribonucleic acid (DNA) and bovine serum albumin (BSA) binding interactions for a series of ruthenium heterocyclic complexes were monitored using ultraviolet-visible (UV-Vis) spectrophotometry, fluorescence emission spectroscopy and agarose gel electrophoresis. Investigations of the DNA interactions for the metal complexes revealed that they are groove-binders with intrinsic binding constants in the order of 104 – 107 M−1.
- Format
- 24 pages
- Format
- Language
- English
- Relation
- Journal of Biomolecular Structure and Dynamics
- Relation
- Maikoo, S., Chakraborty, A., Vukea, N., Dingle, L.M.K., Samson, W.J., Mare, J.A.D.L., Edkins, A.L. and Booysen, I.N., 2020. Ruthenium complexes with mono-or bis-heterocyclic chelates: DNA/BSA binding, Antioxidant and Anticancer studies. Journal of Biomolecular Structure and Dynamics, pp.1-23
- Relation
- Journal of Biomolecular Structure and Dynamics volume number 1 23 2020 1538-0254
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the Taylor and Francis Online Terms and Conditions Statement (https://www.tandfonline.com/terms-and-conditions)
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RU DST/NRF SARChI for Molecular and Cellular Biology of the Eukaryotic Stress Response
RU Department of Biochemistry, Microbiology and Biotechnology
De la Mare, Jo-Anne (Dr)
Edkins, Adrienne Lesley (Associate Prof)
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