- Title
- Attention-deficit/hyperactivity disorder and substance abuse: prevalence and effect of past pharmacotherapy in young adults
- Creator
- Coetze, Corne
- Subject
- Attention-deficit hyperactivity disorder
- Subject
- Substance abuse
- Date Issued
- 2022-04
- Date
- 2022-04
- Type
- Master's theses
- Type
- text
- Identifier
- http://hdl.handle.net/10948/58783
- Identifier
- vital:60121
- Description
- Background: Attention-Deficit/Hyperactivity Disorder (ADHD) frequently occurs in patients with SUD. Several studies demonstrated that ADHD constitutes a significant risk factor for the development of SUDs and suggest that childhood ADHD pharmacotherapy might help prevent the development of SUD. Furthermore, substance use patterns seem to differ between individuals with and without ADHD. Aim: The primary aim of this study was to establish the prevalence of ADHD in SUD in a South African treatment-seeking population, substance use patterns, and to determine the effect of past pharmacotherapy on later life’s functional impairment in adult ADHD treatment-seeking patients with a SUD. Method: Adult treatment-seeking SUD patients (n=360) were recruited from rehabilitation facilities and screened using the ADHD Self-Report Scale Symptom Checklist (ASRS-v1.1). ADHD diagnosis was confirmed (n=52) by the Diagnostic-Interview for ADHD in Adults (DIVA 2.0). Adults with ADHD without SUD (n=48) were recruited from clinicians, retail pharmacies and the general public. Life-time substance use was assessed using a self-report questionnaire. Tobacco use was assessed by the Fagerström Test for Nicotine Dependence (FTND). ADHD-related functional impairment was assessed by the Weiss Functional Impairment Rating Scale (WFIRS). Information on present and life-time use of ADHD medication was obtained. Clinical outcomes between those with and without a history of pharmacotherapy were compared. Results: ADHD is highly prevalent in South African adult treatment-seeking SUD patients. High rates of untreated and unrecognised ADHD were found. Individuals with SUD+ADHD were significantly associated with higher tobacco use. Data indicated increased levels of cannabis consumption among SUD+ADHD individuals, especially among SUD+ADHD females. Furthermore, we found that patients with ADHD were significantly associated with polysubstance use. Our results showed a history of childhood ADHD pharmacotherapy to be associated with less functional ADHD-related impairment across all functional domains and a decreased risk for substance use in later life. Abstract Conclusion: High rates of untreated and unrecognised ADHD were found among treatment-seeking SUD patients. ADHD patients appeared to self-medicate to cope with their symptoms. Childhood ADHD pharmacotherapy might be associated with a decreased risk for substance use in adulthood and lower ADHD-related impairment. Despite study limitations, these findings underline the importance of early ADHD detection and treatment, which might prevent substance use.
- Description
- Thesis (MA) -- Faculty of Health Sciences, 2022
- Format
- computer
- Format
- online resource
- Format
- application/pdf
- Format
- 1 online resource (xvii, 245 pages)
- Format
- Publisher
- Nelson Mandela University
- Publisher
- Faculty of Health Sciences
- Language
- English
- Rights
- Nelson Mandela University
- Rights
- All Rights Reserved
- Rights
- Open Access
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NMU School of Clinical Care Sciences
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | SOURCE1 | Coetzee, C.pdf | 19 MB | Adobe Acrobat PDF | View Details Download |