Determination of erythromycin in serum and urine by high performance liquid chromatography with ultraviolet detection

Title: Determination of erythromycin in serum and urine by high performance liquid chromatography with ultraviolet detection
Creator: Stubbs, Christopher
Creator: Haigh, John M
Creator: Kanfer, Isadore
Date Issued: 1985
Date: 1985
Type: text
Type: Article
Identifier: vital:6428
Identifier: http://hdl.handle.net/10962/d1006576
Description: A high-performance liquid chromatographic analysis of erythromycin in human serum and urine with UV detection at 200 nm is presented. The method involves a solid-phase extraction procedure followed by a simple phase separation step and chromatography on a reversed-phase column. The method has sensitivity limits of 0.25 and 1.0 g/mL in serum and urine, respectively, and is sufficiently sensitive to monitor concentrations of erythromycin in human serum and urine after the administration of a single 500-mg erythromycin stearate tablet.
Format: 3 pages
Format: pdf
Language: English
Relation: Stubbs, C. and Haigh, J.M. and Kanfer, I. (1985) Determination of erythromycin in serum and urine by high performance liquid chromatography with ultraviolet detection. Journal of Pharmaceutical Sciences, 74 (10). pp. 1126-1128. Available: http://dx.doi.org/10.1002/jps.2600741027

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Kanfer, Isadore (Prof)

RU Department of Pharmacy

Haigh, JM (Prof)

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