- Title
- Synthesis, characterization and DPPH scavenging activity of some benzimidazole derivatives
- Creator
- Odame, Felix
- Creator
- Krause, Jason
- Creator
- Hosten, Eric C
- Creator
- Betz, Richard
- Creator
- Lobb, Kevin A
- Creator
- Tshentu, Zenixole R
- Creator
- Frost, Carminita L
- Subject
- To be catalogued
- Date Issued
- 2018
- Date
- 2018
- Type
- text
- Type
- article
- Identifier
- http://hdl.handle.net/10962/447209
- Identifier
- vital:74592
- Identifier
- xlink:href="https://dx.doi.org/10.4314/bcse.v32i2.8 "
- Description
- A base-catalyzed conversion of aldehydes to benzimidazoles has been achieved. The compounds have been characterized by IR, NMR, micoranalysis, and GC-MS. The reaction for the formation of benzimidazoles has been monitored with 1 H NMR and IR. The crystal structures of two derivatives, 2-(2- chlorophenyl)-1H-benzimidazole and 2-(1H-benzimidazol-2-yl)-4-nitrophenol, are presented. A study of the DPPH scavenging activity of these compounds showed that 2-(1H-benzimidazol-2-yl)phenol (2), 2-p-tolyl-1Hbenzimidazole (3) and 2-(4-methoxyphenyl)-1H-benzimidazole (7) gave IC50 values 1974, 773 and 800 µM.
- Format
- computer
- Format
- online resource
- Format
- application/pdf
- Format
- 1 online resource (14 pages)
- Format
- Publisher
- Bulletin of the Chemical Society of Ethiopia
- Language
- English
- Relation
- Bulletin of the Chemical Society of Ethiopia
- Relation
- Odame, F., Krause, J., Hosten, E.C., Betz, R., Lobb, K., Tshentu, Z.R. and Frost, C.L., 2018. Synthesis, characterization and DPPH scavenging activity of some benzimidazole derivatives. Bulletin of the Chemical Society of Ethiopia, 32(2), pp.271-284
- Relation
- Bulletin of the Chemical Society of Ethiopia volume 32 number 2 p. 271 2018 1726-801X
- Rights
- Publisher
- Rights
- Use of this resource is governed by the terms and conditions of the Bulletin of the Chemical Society of Ethiopia Open Access Terms and Conditions Statement (https://www.ajol.info/index.php/bcse/about)
- Rights
- Closed Access
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Collections
Lobb, Kevin Allan (Assoc Prof)
RU Department of Chemistry
SDG 03. Good Health and Well-Being
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | SOURCE1 | Synthesis, characterization and DPPH scavenging activity of some benzimidazole derivatives.pdf | 714 KB | Adobe Acrobat PDF | View Details Download |