Investigating the roles of HOP isoforms in KSHV biology
- Matandirotya, Lorraine Tariro
- Authors: Matandirotya, Lorraine Tariro
- Date: 2022-10-14
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/365257 , vital:65721
- Description: Thesis embargoed. Possible release date set for early 2025. , Thesis (MSc) -- Faculty of Science, Biochemistry and Microbiology, 2022
- Full Text:
- Date Issued: 2022-10-14
- Authors: Matandirotya, Lorraine Tariro
- Date: 2022-10-14
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/365257 , vital:65721
- Description: Thesis embargoed. Possible release date set for early 2025. , Thesis (MSc) -- Faculty of Science, Biochemistry and Microbiology, 2022
- Full Text:
- Date Issued: 2022-10-14
Les Trinitaires
- Unknown
- Authors: Unknown
- Subjects: McGregor, Chris -- 1936-1990 , Jazz
- Language: French
- Type: Text
- Identifier: vital:13782 , http://hdl.handle.net/10962/d1012814
- Description: Original poster for the music festival Jazz en Lorraine, in France, organised by the association Les Trinitaires.
- Full Text:
- Authors: Unknown
- Subjects: McGregor, Chris -- 1936-1990 , Jazz
- Language: French
- Type: Text
- Identifier: vital:13782 , http://hdl.handle.net/10962/d1012814
- Description: Original poster for the music festival Jazz en Lorraine, in France, organised by the association Les Trinitaires.
- Full Text:
The Women’s Development Foundation Award to Lorraine Keamogecoe Losabe
- Date: 1999 , 2022-10-17
- Subjects: Bam, Brigalia , Losabe, Lorraine Keamogecoe -- Awards
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/57396 , vital:57605
- Description: The Women's Development Award to Lorraine Keamogecoe Losabe, "honoring your contribution to the first Democratic National Assembly of the Republic of South Africa 1994-1999" , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 1999
- Date: 1999 , 2022-10-17
- Subjects: Bam, Brigalia , Losabe, Lorraine Keamogecoe -- Awards
- Language: English
- Type: realia
- Identifier: http://hdl.handle.net/10948/57396 , vital:57605
- Description: The Women's Development Award to Lorraine Keamogecoe Losabe, "honoring your contribution to the first Democratic National Assembly of the Republic of South Africa 1994-1999" , Donated/gifted to Nelson Mandela University Archives , Forms part of: Brigalia Bam collection
- Full Text: false
- Date Issued: 1999
Yellowwood
- Authors: Skead, C J (Cuthbert John)
- Date: 1977-04-22
- Subjects: Podocarpus falcatus -- South Africa -- Photographs , Trees -- South Africa -- Photographs
- Language: English
- Type: mixed material , photographs , landscape photographs
- Identifier: http://hdl.handle.net/10962/116855 , vital:34452
- Description: Caption "Common or Outeniqua Yellowood, Podcarpus falcatus in front of garden of St Andrews Prep School, West Hill, Grahamstown. Taken 22 April 1977. Planted in 1935, along with the Kaffirboom, Erythrina caffra, to the right by Mr C. Griffin Mullins, housemaster and later headmaster of the school, when his son R. Lorraine G. Mullins was born. An old friend, Mr F. H. Holland, brought Mr. Mullins a small yellowwood seedling so small that it fitted into a matchbox. The kaffirboom seedling was not much larger. Information from Mr. Griffin Mullins himself. The photo taken 1977, shows the trees after 42 years growth. The yellowwood's trunk one metre from the ground was 784 mm in diameter, the Kaffirboom's; 1, 219 mm.”
- Full Text: false
- Date Issued: 1977-04-22
- Authors: Skead, C J (Cuthbert John)
- Date: 1977-04-22
- Subjects: Podocarpus falcatus -- South Africa -- Photographs , Trees -- South Africa -- Photographs
- Language: English
- Type: mixed material , photographs , landscape photographs
- Identifier: http://hdl.handle.net/10962/116855 , vital:34452
- Description: Caption "Common or Outeniqua Yellowood, Podcarpus falcatus in front of garden of St Andrews Prep School, West Hill, Grahamstown. Taken 22 April 1977. Planted in 1935, along with the Kaffirboom, Erythrina caffra, to the right by Mr C. Griffin Mullins, housemaster and later headmaster of the school, when his son R. Lorraine G. Mullins was born. An old friend, Mr F. H. Holland, brought Mr. Mullins a small yellowwood seedling so small that it fitted into a matchbox. The kaffirboom seedling was not much larger. Information from Mr. Griffin Mullins himself. The photo taken 1977, shows the trees after 42 years growth. The yellowwood's trunk one metre from the ground was 784 mm in diameter, the Kaffirboom's; 1, 219 mm.”
- Full Text: false
- Date Issued: 1977-04-22
Lorraine Suburb, Walmer, Port Elizabeth
- Authors: Skead, C J (Cuthbert John)
- Date: 1994-08-23
- Subjects: Protea cynaroides -- South Africa -- Eastern Cape Plants -- South Africa -- Eastern Cape
- Type: still image
- Identifier: vital:12393 , http://hdl.handle.net/10962/d1013800
- Description: Protea cynaroides var. elliptica (Port Elizabeth form). In natural fynbosveld soon to be covered by urban sprawl, spelling out the last of this distinctive fynbos form. Encroaching houses seen in the background.
- Full Text: false
- Date Issued: 1994-08-23
- Authors: Skead, C J (Cuthbert John)
- Date: 1994-08-23
- Subjects: Protea cynaroides -- South Africa -- Eastern Cape Plants -- South Africa -- Eastern Cape
- Type: still image
- Identifier: vital:12393 , http://hdl.handle.net/10962/d1013800
- Description: Protea cynaroides var. elliptica (Port Elizabeth form). In natural fynbosveld soon to be covered by urban sprawl, spelling out the last of this distinctive fynbos form. Encroaching houses seen in the background.
- Full Text: false
- Date Issued: 1994-08-23
Recombinant expression, purification and in vitro interaction analysis of HOP and RhoC
- Vaaltyn, Michaelone Chantelle
- Authors: Vaaltyn, Michaelone Chantelle
- Date: 2016
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/64523 , vital:28555
- Description: Expected release date-May 2019
- Full Text:
- Date Issued: 2016
- Authors: Vaaltyn, Michaelone Chantelle
- Date: 2016
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/64523 , vital:28555
- Description: Expected release date-May 2019
- Full Text:
- Date Issued: 2016
Lorraine Suburb, Walmer, Port Elizabeth
- Authors: Skead, C J (Cuthbert John)
- Date: 1994-08-23
- Subjects: Protea cynaroides -- South Africa -- Eastern Cape , Plants -- South Africa -- Eastern Cape , Vanderplank, Helen J -- Photographs
- Type: still image
- Identifier: vital:12391 , http://hdl.handle.net/10962/d1013798
- Description: Protea cynaroides var. elliptica (Port Elizabeth form). In natural fynbosveld soon to be covered by urban sprawl, spelling out the last of this distinctive fynbos form.
- Full Text: false
- Date Issued: 1994-08-23
- Authors: Skead, C J (Cuthbert John)
- Date: 1994-08-23
- Subjects: Protea cynaroides -- South Africa -- Eastern Cape , Plants -- South Africa -- Eastern Cape , Vanderplank, Helen J -- Photographs
- Type: still image
- Identifier: vital:12391 , http://hdl.handle.net/10962/d1013798
- Description: Protea cynaroides var. elliptica (Port Elizabeth form). In natural fynbosveld soon to be covered by urban sprawl, spelling out the last of this distinctive fynbos form.
- Full Text: false
- Date Issued: 1994-08-23
Lorraine Suburb, Walmer, Port Elizabeth
- Authors: Skead, C J (Cuthbert John)
- Date: 1994-08-23
- Subjects: Protea cynaroides -- South Africa -- Eastern Cape , Plants -- South Africa -- Eastern Cape , Vanderplank, Helen J -- Photographs
- Type: still image
- Identifier: vital:12392 , http://hdl.handle.net/10962/d1013799
- Description: Protea cynaroides var. elliptica (Port Elizabeth form). In natural fynbosveld soon to be covered by urban sprawl, spelling out the last of this distinctive fynbos form.
- Full Text: false
- Date Issued: 1994-08-23
- Authors: Skead, C J (Cuthbert John)
- Date: 1994-08-23
- Subjects: Protea cynaroides -- South Africa -- Eastern Cape , Plants -- South Africa -- Eastern Cape , Vanderplank, Helen J -- Photographs
- Type: still image
- Identifier: vital:12392 , http://hdl.handle.net/10962/d1013799
- Description: Protea cynaroides var. elliptica (Port Elizabeth form). In natural fynbosveld soon to be covered by urban sprawl, spelling out the last of this distinctive fynbos form.
- Full Text: false
- Date Issued: 1994-08-23
Investigating the role of heat shock proteins (Hsps) 40, 70 and 90 in the life cycle of Theiler's murine encephalomyelitis virus (TMEV)
- Mutsvunguma, Lorraine Zvichapera
- Authors: Mutsvunguma, Lorraine Zvichapera
- Date: 2011
- Subjects: Heat shock proteins , Picornaviruses , Encephalomyelitis
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:3966 , http://hdl.handle.net/10962/d1004025 , Heat shock proteins , Picornaviruses , Encephalomyelitis
- Description: Introduction: Picornaviruses are a family of RNA viruses which are economically and clinically significant. Like many other viruses, picornaviruses utilise host cell machinery to facilitate their replication and assembly, including heat shock proteins (Hsps). The aim of this research was to investigate the role of Hsp40, Hsp70 and Hsp90 during picornavirus infection using the cardiovirus, Theiler’s murine encephalomyelitis virus (TMEV), as a study model. Methodology: Picornavirus VP1 capsid proteins were analysed by multiple sequence alignment and multiple structural comparisons. Protein domain architecture was used to analyse Hsp90 cellular and viral client proteins. Effects of Hsp90 inhibitors, novobiocin and geldanamycin, on TMEV growth in BHK-21 cells was observed over a 48hr period. Localisation of Hsp40, Hsp90 and Hsp70 in TMEV-infected BHK-21 cells was investigated by indirect immunofluorescence and confocal microscopy. Results and Discussion: VP1 proteins of picornaviruses are highly divergent within the family at the amino acid level, which might be linked to the protein’s function in determining virus tropism and antibody neutralisation. An eight-stranded anti-parallel beta-barrel structure was found conserved in the VP1 protein structures which might be linked to the highly conserved picornavirus capsid assembly process. Absence of a common protein domain between Hsp90 viral and cellular client proteins that might be functionally connected to Hsp90, suggests that Hsp90 most likely recognises surface features rather than sequence motifs/patterns. The Hsp90 inhibitors, novobiocin and geldanamycin, had a negative effect on virus growth as virus-induced cytopathic effect was not observed in treated cell after 48hrs. TMEV 2C protein was detected by Western analysis in infected cell lysates treated with geldanamycin but not novobiocin, suggesting novobiocin affects the translation or processing of TMEV 2C. Immunofluorescence analysis of TMEV-infected cells showed a relocalisation of Hsp40 into the nucleus during infection. Overlap of Hsp40 and TMEV P1 was observed in the perinuclear region, suggesting colocalisation between these proteins. Hsp70 converged around the replication complex during infection but did not overlap with TMEV 2C. Hsp90 concentrated in the region of the replication complex where it overlapped with TMEV 2C and this redistribution was found to be dependent on the stage of infection. The overlap between Hsp90 and TMEV 2C signals observed, suggested colocalisation between the two proteins. Conclusion: This study identified Hsp90, Hsp70 and Hsp40 as possible host factors required in TMEV replication.
- Full Text:
- Date Issued: 2011
- Authors: Mutsvunguma, Lorraine Zvichapera
- Date: 2011
- Subjects: Heat shock proteins , Picornaviruses , Encephalomyelitis
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:3966 , http://hdl.handle.net/10962/d1004025 , Heat shock proteins , Picornaviruses , Encephalomyelitis
- Description: Introduction: Picornaviruses are a family of RNA viruses which are economically and clinically significant. Like many other viruses, picornaviruses utilise host cell machinery to facilitate their replication and assembly, including heat shock proteins (Hsps). The aim of this research was to investigate the role of Hsp40, Hsp70 and Hsp90 during picornavirus infection using the cardiovirus, Theiler’s murine encephalomyelitis virus (TMEV), as a study model. Methodology: Picornavirus VP1 capsid proteins were analysed by multiple sequence alignment and multiple structural comparisons. Protein domain architecture was used to analyse Hsp90 cellular and viral client proteins. Effects of Hsp90 inhibitors, novobiocin and geldanamycin, on TMEV growth in BHK-21 cells was observed over a 48hr period. Localisation of Hsp40, Hsp90 and Hsp70 in TMEV-infected BHK-21 cells was investigated by indirect immunofluorescence and confocal microscopy. Results and Discussion: VP1 proteins of picornaviruses are highly divergent within the family at the amino acid level, which might be linked to the protein’s function in determining virus tropism and antibody neutralisation. An eight-stranded anti-parallel beta-barrel structure was found conserved in the VP1 protein structures which might be linked to the highly conserved picornavirus capsid assembly process. Absence of a common protein domain between Hsp90 viral and cellular client proteins that might be functionally connected to Hsp90, suggests that Hsp90 most likely recognises surface features rather than sequence motifs/patterns. The Hsp90 inhibitors, novobiocin and geldanamycin, had a negative effect on virus growth as virus-induced cytopathic effect was not observed in treated cell after 48hrs. TMEV 2C protein was detected by Western analysis in infected cell lysates treated with geldanamycin but not novobiocin, suggesting novobiocin affects the translation or processing of TMEV 2C. Immunofluorescence analysis of TMEV-infected cells showed a relocalisation of Hsp40 into the nucleus during infection. Overlap of Hsp40 and TMEV P1 was observed in the perinuclear region, suggesting colocalisation between these proteins. Hsp70 converged around the replication complex during infection but did not overlap with TMEV 2C. Hsp90 concentrated in the region of the replication complex where it overlapped with TMEV 2C and this redistribution was found to be dependent on the stage of infection. The overlap between Hsp90 and TMEV 2C signals observed, suggested colocalisation between the two proteins. Conclusion: This study identified Hsp90, Hsp70 and Hsp40 as possible host factors required in TMEV replication.
- Full Text:
- Date Issued: 2011
Drum majorettes led by Lorraine Imphy possibly at Rag week, 1966
- Date: 1966
- Subjects: Rhodes University -- Rag -- Photographs Rhodes University -- History -- Photographs Rhodes University -- Students -- Photographs
- Type: Image
- Identifier: http://hdl.handle.net/10962/9019 , vital:21453 , PIC/M 6778
- Description: This image is held at the Cory Library for Humanities Research at Rhodes University. For further information contact cory@ru.ac.za. The digitisation of this image was made possible through a generous grant received from the Andrew W. Mellon Foundation 2014-2017.
- Full Text: false
- Date Issued: 1966
- Date: 1966
- Subjects: Rhodes University -- Rag -- Photographs Rhodes University -- History -- Photographs Rhodes University -- Students -- Photographs
- Type: Image
- Identifier: http://hdl.handle.net/10962/9019 , vital:21453 , PIC/M 6778
- Description: This image is held at the Cory Library for Humanities Research at Rhodes University. For further information contact cory@ru.ac.za. The digitisation of this image was made possible through a generous grant received from the Andrew W. Mellon Foundation 2014-2017.
- Full Text: false
- Date Issued: 1966
Writing, identity, and change : a narrative case study of the use of journals to promote reflexivity within a Drama Studies curriculum
- Authors: Sutherland, Alexandra
- Date: 2005
- Subjects: Drama -- Study and teaching (Higher) -- South Africa Drama in education Scholarly publishing Academic writing Reflection (Philosophy) Playwriting
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1845 , http://hdl.handle.net/10962/d1004384
- Description: The study adopts a case study examination of three student reflective joumals written about class and field based applied Drama experiences over one year. The journals were written as part of a curriculum outcome to develop reflective practice, for one Drama Honours paper (Educational Drama and Theatre) at Rhodes University Drama Department, South Africa. Based on a narrative inquiry approach, the study documents the changes in identity, discourse, and representation of self and other, which emerge through the journal writing process. The research analyses how identities are constructed through reflective writing practices, and how these identities might relate to the arguments for the development of reflexivity. The development of reflexivity is seen as integral to contemporary educational policies associated with lifelong learning, and the skills required of graduates in South Africa's emerging democracy. These policies centre on means of preparing students for a world characterised by change and instability, or what Barnett (2000) has termed a "supercomplex world". The research findings suggest that journal writing within a Drama Studies curriculum, allows students to construct subjectivities which support Barnett's claim that "the main pedagogical task in a university is not that of the transmission of knowledge but of promoting forms of human being appropriate to the conditions of supercomplexity" (Barnett, 2000b: 164). In addition, the development of different writing genres within a Drama Studies curriculum allows students to develop disciplinarily relevant ways of discussing and researching artistic processes and products. A reflective journal is a potential site for students to interrogate and construct emerging identities which enable them to negotiate diversity, thus preparing them for their lives beyond the university.
- Full Text:
- Date Issued: 2005
- Authors: Sutherland, Alexandra
- Date: 2005
- Subjects: Drama -- Study and teaching (Higher) -- South Africa Drama in education Scholarly publishing Academic writing Reflection (Philosophy) Playwriting
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1845 , http://hdl.handle.net/10962/d1004384
- Description: The study adopts a case study examination of three student reflective joumals written about class and field based applied Drama experiences over one year. The journals were written as part of a curriculum outcome to develop reflective practice, for one Drama Honours paper (Educational Drama and Theatre) at Rhodes University Drama Department, South Africa. Based on a narrative inquiry approach, the study documents the changes in identity, discourse, and representation of self and other, which emerge through the journal writing process. The research analyses how identities are constructed through reflective writing practices, and how these identities might relate to the arguments for the development of reflexivity. The development of reflexivity is seen as integral to contemporary educational policies associated with lifelong learning, and the skills required of graduates in South Africa's emerging democracy. These policies centre on means of preparing students for a world characterised by change and instability, or what Barnett (2000) has termed a "supercomplex world". The research findings suggest that journal writing within a Drama Studies curriculum, allows students to construct subjectivities which support Barnett's claim that "the main pedagogical task in a university is not that of the transmission of knowledge but of promoting forms of human being appropriate to the conditions of supercomplexity" (Barnett, 2000b: 164). In addition, the development of different writing genres within a Drama Studies curriculum allows students to develop disciplinarily relevant ways of discussing and researching artistic processes and products. A reflective journal is a potential site for students to interrogate and construct emerging identities which enable them to negotiate diversity, thus preparing them for their lives beyond the university.
- Full Text:
- Date Issued: 2005
Nancy Jazz Pulsations
- Unknown
- Authors: Unknown
- Subjects: McGregor, Chris -- 1936-1990 , Brotherhood of Breath (Musical group) , Jazz
- Language: French
- Type: Text
- Identifier: vital:13784 , http://hdl.handle.net/10962/d1012816
- Description: Original flier for the 10th Nancy Jazz Pulsations festival (France).
- Full Text:
- Authors: Unknown
- Subjects: McGregor, Chris -- 1936-1990 , Brotherhood of Breath (Musical group) , Jazz
- Language: French
- Type: Text
- Identifier: vital:13784 , http://hdl.handle.net/10962/d1012816
- Description: Original flier for the 10th Nancy Jazz Pulsations festival (France).
- Full Text:
Yellowwood
- Authors: Skead, C J (Cuthbert John)
- Date: 1977-04
- Subjects: Podocarpus falcatus -- South Africa -- Photographs , Trees -- South Africa -- Photographs
- Language: English
- Type: mixed material , photographs , landscape photographs
- Identifier: http://hdl.handle.net/10962/116835 , vital:34451
- Description: Caption "Common or Outeniqua Yellowood, Podcarpus falcatus in front of garden of St Andrews Prep School, West Hill, Grahamstown. Taken April 1977 from Leicester Street Side. Kaffirboom, Erythrina caffra, at left. The yellowwood was planted in 1935 when by Mr. Griffin Mullins', when his son Lorraine was born. The tree was brought Mr. Mullins by an old friend, Mr. F. H. Holland in a matchbox. The kaffirboom seedling was not much larger. The photo taken 1977, shows the trees after 42 years growth. The bole diameters at 1 m from the groumd were - Y'wood = 784 mm; the Kaffirboom = 1, 219 mm”
- Full Text: false
- Date Issued: 1977-04
- Authors: Skead, C J (Cuthbert John)
- Date: 1977-04
- Subjects: Podocarpus falcatus -- South Africa -- Photographs , Trees -- South Africa -- Photographs
- Language: English
- Type: mixed material , photographs , landscape photographs
- Identifier: http://hdl.handle.net/10962/116835 , vital:34451
- Description: Caption "Common or Outeniqua Yellowood, Podcarpus falcatus in front of garden of St Andrews Prep School, West Hill, Grahamstown. Taken April 1977 from Leicester Street Side. Kaffirboom, Erythrina caffra, at left. The yellowwood was planted in 1935 when by Mr. Griffin Mullins', when his son Lorraine was born. The tree was brought Mr. Mullins by an old friend, Mr. F. H. Holland in a matchbox. The kaffirboom seedling was not much larger. The photo taken 1977, shows the trees after 42 years growth. The bole diameters at 1 m from the groumd were - Y'wood = 784 mm; the Kaffirboom = 1, 219 mm”
- Full Text: false
- Date Issued: 1977-04
Rhodes University Graduation Ceremony 2014
- Authors: Rhodes University
- Date: 2014
- Language: English
- Type: text
- Identifier: vital:8148 , http://hdl.handle.net/10962/d1009493
- Description: Rhodes University Graduation Ceremonies [at] 1820 Settlers National Monument Thursday, 10 April at 10.00 & 17:00 [and] Friday, 11 April at 10:00; 14:30 & 18:00 [and] Saturday, 12 April at 10:00 , Rhodes University Awards, Scholarships,Bursaries and Prizes 2014
- Full Text:
- Date Issued: 2014
- Authors: Rhodes University
- Date: 2014
- Language: English
- Type: text
- Identifier: vital:8148 , http://hdl.handle.net/10962/d1009493
- Description: Rhodes University Graduation Ceremonies [at] 1820 Settlers National Monument Thursday, 10 April at 10.00 & 17:00 [and] Friday, 11 April at 10:00; 14:30 & 18:00 [and] Saturday, 12 April at 10:00 , Rhodes University Awards, Scholarships,Bursaries and Prizes 2014
- Full Text:
- Date Issued: 2014
Rhodeo, Vol. 27, No. 1
- Date: 1973-02-22
- Subjects: Grahamstown -- Newspapers , Journalism, Students -- South Africa , Rhodes University -- Activate , Rhodes University -- Students , Student newspapers and periodicals -- South Africa
- Language: English
- Type: Text
- Identifier: vital:14643 , http://hdl.handle.net/10962/d1019515
- Description: Rhodeo is the Independent Student Newspaper of Rhodes University. Located in Grahamstown, Rhodeo was established in 1947, and renamed in 1994 as Activate. During apartheid Rhodeo became an active part of the struggle for freedom of expression as part of the now defunct South African Student Press Union. Currently Activate is committed to informing Rhodes University students, staff and community members about relevant issues, mainly on campus. These issues range from hard news to more creative journalism. While Activate acts as a news source, one of its main objectives it to be accessible as a training ground for student journalists. The newspaper is run entirely by the students and is published twice a term. Activate is a free newspaper which receives an annual grant from the Rhodes University Student Representative Council, however, majority of its revenue is generated through advertising.
- Full Text:
- Date Issued: 1973-02-22
- Date: 1973-02-22
- Subjects: Grahamstown -- Newspapers , Journalism, Students -- South Africa , Rhodes University -- Activate , Rhodes University -- Students , Student newspapers and periodicals -- South Africa
- Language: English
- Type: Text
- Identifier: vital:14643 , http://hdl.handle.net/10962/d1019515
- Description: Rhodeo is the Independent Student Newspaper of Rhodes University. Located in Grahamstown, Rhodeo was established in 1947, and renamed in 1994 as Activate. During apartheid Rhodeo became an active part of the struggle for freedom of expression as part of the now defunct South African Student Press Union. Currently Activate is committed to informing Rhodes University students, staff and community members about relevant issues, mainly on campus. These issues range from hard news to more creative journalism. While Activate acts as a news source, one of its main objectives it to be accessible as a training ground for student journalists. The newspaper is run entirely by the students and is published twice a term. Activate is a free newspaper which receives an annual grant from the Rhodes University Student Representative Council, however, majority of its revenue is generated through advertising.
- Full Text:
- Date Issued: 1973-02-22
Some aspects of the Franco-German economic relations between the two world wars
- Authors: Wolf, Hans J
- Date: 1970
- Subjects: Economic history -- 1918-1945 , France -- Economic conditions -- 20th century , Germany -- Economic conditions -- 20th century , France -- Foreign relations -- Germany , Germany -- Foreign relations -- France
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:1067 , http://hdl.handle.net/10962/d1007687
- Description: From Preface: In this thesis I have aimed at covering a field in Economic History where not many suitable publications are available in English. During the interwar period, the maintenance of peace and harmonious international relations was directly dependent on a reconciliation of the conflicting interests between France and Germany. In studying the economic implications of the Franco-German antagonism, I have tried to throw light upon the crucial role which this relationship played. The Appendix offers a quantitative survey of economic conditions in the two countries and of the relevant production and exchange problems. To assist the reader who is not completely familiar with this period, a brief summary of the relevant conferences, agreements and treaties is also offered in the Appendix, as well as some short biographical notes. I would like to make it clear, however, that this thesis is neither supposed to be a paraphrase of the Appendix, nor a mere treatise on the commercial relations between the two countries concerned. I aimed rather at revealing the forces behind the events and at illustrating how economic problems became quite often subject to political and military considerations. When trying to attain some understanding of Franco-German relations, it seems advisable to look not only at the interbellum period, but in the first instance to become aware of the currents of history which finally led to the two disastrous World Wars.
- Full Text:
- Date Issued: 1970
- Authors: Wolf, Hans J
- Date: 1970
- Subjects: Economic history -- 1918-1945 , France -- Economic conditions -- 20th century , Germany -- Economic conditions -- 20th century , France -- Foreign relations -- Germany , Germany -- Foreign relations -- France
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:1067 , http://hdl.handle.net/10962/d1007687
- Description: From Preface: In this thesis I have aimed at covering a field in Economic History where not many suitable publications are available in English. During the interwar period, the maintenance of peace and harmonious international relations was directly dependent on a reconciliation of the conflicting interests between France and Germany. In studying the economic implications of the Franco-German antagonism, I have tried to throw light upon the crucial role which this relationship played. The Appendix offers a quantitative survey of economic conditions in the two countries and of the relevant production and exchange problems. To assist the reader who is not completely familiar with this period, a brief summary of the relevant conferences, agreements and treaties is also offered in the Appendix, as well as some short biographical notes. I would like to make it clear, however, that this thesis is neither supposed to be a paraphrase of the Appendix, nor a mere treatise on the commercial relations between the two countries concerned. I aimed rather at revealing the forces behind the events and at illustrating how economic problems became quite often subject to political and military considerations. When trying to attain some understanding of Franco-German relations, it seems advisable to look not only at the interbellum period, but in the first instance to become aware of the currents of history which finally led to the two disastrous World Wars.
- Full Text:
- Date Issued: 1970
Grammy winning jazz
- Authors: Thomas, Cornelius
- Date: 2001-03-02
- Subjects: Valdés, Chucho Valdés, Chucho -- Cuba Grammy Awards
- Type: article
- Identifier: http://hdl.handle.net/10962/41167 , vital:25060 , This image is held at the Cory Library for Humanities Research at Rhodes University. For further information contact cory@ru.ac.za. The digitisation of this image was made possible through a generous grant received from the Andrew W. Mellon Foundation 2014-2017. , MS 20 041
- Description: Photocopied article from the newspaper The Daily Dispatch about Chucho Valdes, a jazz musicians
- Full Text:
- Date Issued: 2001-03-02
- Authors: Thomas, Cornelius
- Date: 2001-03-02
- Subjects: Valdés, Chucho Valdés, Chucho -- Cuba Grammy Awards
- Type: article
- Identifier: http://hdl.handle.net/10962/41167 , vital:25060 , This image is held at the Cory Library for Humanities Research at Rhodes University. For further information contact cory@ru.ac.za. The digitisation of this image was made possible through a generous grant received from the Andrew W. Mellon Foundation 2014-2017. , MS 20 041
- Description: Photocopied article from the newspaper The Daily Dispatch about Chucho Valdes, a jazz musicians
- Full Text:
- Date Issued: 2001-03-02
Breast cancer: current developments in molecular approaches to diagnosis and treatment
- de la Mare, Jo-Anne, Contu, Lara, Hunter, Morgan C, Moyo, Buhle, Sterrenberg, Jason N, Dhanani, Karim C H, Mutsvunguma, Lorraine Z, Edkins, Adrienne L
- Authors: de la Mare, Jo-Anne , Contu, Lara , Hunter, Morgan C , Moyo, Buhle , Sterrenberg, Jason N , Dhanani, Karim C H , Mutsvunguma, Lorraine Z , Edkins, Adrienne L
- Date: 2014
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/164819 , vital:41175 , DOI: 10.2174/15748928113086660046
- Description: Due to the high heterogeneity of breast cancers, numerous recent patents describe improved methods of detection and classification which promise better patient prognosis and treatment. In particular, there has been a shift towards more effective genetic screening to identify specific mutations associated with breast tumours, which may lead to “personalised medicine” with improved outcomes. Two challenging areas of breast cancer research involve the development of treatments for the highly aggressive triple negative breast cancer subtype as well as the chemotherapy-resistant cancer stem cell subpopulation. In addition, despite numerous recent advances in breast cancer treatment in woman, male breast cancer remains poorly understood and there are limited therapies available which are developed specifically for men. This review serves to report on important developments in the treatment of breast malignancies patented in the past two years as well as to highlight the current gaps in the field of breast cancer therapeutics and areas which require further study.
- Full Text:
- Date Issued: 2014
- Authors: de la Mare, Jo-Anne , Contu, Lara , Hunter, Morgan C , Moyo, Buhle , Sterrenberg, Jason N , Dhanani, Karim C H , Mutsvunguma, Lorraine Z , Edkins, Adrienne L
- Date: 2014
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/164819 , vital:41175 , DOI: 10.2174/15748928113086660046
- Description: Due to the high heterogeneity of breast cancers, numerous recent patents describe improved methods of detection and classification which promise better patient prognosis and treatment. In particular, there has been a shift towards more effective genetic screening to identify specific mutations associated with breast tumours, which may lead to “personalised medicine” with improved outcomes. Two challenging areas of breast cancer research involve the development of treatments for the highly aggressive triple negative breast cancer subtype as well as the chemotherapy-resistant cancer stem cell subpopulation. In addition, despite numerous recent advances in breast cancer treatment in woman, male breast cancer remains poorly understood and there are limited therapies available which are developed specifically for men. This review serves to report on important developments in the treatment of breast malignancies patented in the past two years as well as to highlight the current gaps in the field of breast cancer therapeutics and areas which require further study.
- Full Text:
- Date Issued: 2014
Localisation of Theiler's murine encephalomyelitis virus protein 2C to the golgi apparatus using antibodies generated against a peptide region:
- Jauka, Tembisa, Mutsvunguma, Lorraine Z, Boshoff, Aileen, Edkins, Adrienne L, Knox, Caroline M
- Authors: Jauka, Tembisa , Mutsvunguma, Lorraine Z , Boshoff, Aileen , Edkins, Adrienne L , Knox, Caroline M
- Date: 2010
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/165074 , vital:41206 , DOI: 10.1016/j.jviromet.2010.05.009
- Description: The picornavirus 2C protein is highly conserved and indispensible for virus replication. Polyclonal antibodies against Theiler's murine encephalomyelitis virus (TMEV) 2C protein were generated by immunisation of rabbits with a peptide comprising amino acids 31–210 of the protein. Antibodies were used to investigate the localisation of 2C in infected cells by indirect immunofluorescence and confocal microscopy. Analysis of infected cells revealed that the distribution of 2C changed during infection.
- Full Text:
- Date Issued: 2010
- Authors: Jauka, Tembisa , Mutsvunguma, Lorraine Z , Boshoff, Aileen , Edkins, Adrienne L , Knox, Caroline M
- Date: 2010
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/165074 , vital:41206 , DOI: 10.1016/j.jviromet.2010.05.009
- Description: The picornavirus 2C protein is highly conserved and indispensible for virus replication. Polyclonal antibodies against Theiler's murine encephalomyelitis virus (TMEV) 2C protein were generated by immunisation of rabbits with a peptide comprising amino acids 31–210 of the protein. Antibodies were used to investigate the localisation of 2C in infected cells by indirect immunofluorescence and confocal microscopy. Analysis of infected cells revealed that the distribution of 2C changed during infection.
- Full Text:
- Date Issued: 2010
A statistical model for valuation of residential property in the Nelson Mandela Metropolitan area
- Authors: Van der Byl, Calven
- Date: 2012
- Subjects: Residential real estate -- Port Elizabeth , Housing -- Port Elizabeth
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:9347 , http://hdl.handle.net/10948/d1020045
- Description: This study applies a process of correlation analysis and hedonic based modelling to investigate the influence of housing attributes and date of sale on transaction prices for residential real estate in the Nelson Mandela Metropole area. Availability of reliable data is a challenge in real estate studies in South Africa. This study integrates several publicly available resources for the purposes of constructing a statistical model. A model is constructed based on a forward variable selection routine using selection criteria. The resulting model shows six highly significant variables that can be used for modelling purposes. The resulting model is used to make comparisons in the value of the geographical location.
- Full Text:
- Date Issued: 2012
- Authors: Van der Byl, Calven
- Date: 2012
- Subjects: Residential real estate -- Port Elizabeth , Housing -- Port Elizabeth
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:9347 , http://hdl.handle.net/10948/d1020045
- Description: This study applies a process of correlation analysis and hedonic based modelling to investigate the influence of housing attributes and date of sale on transaction prices for residential real estate in the Nelson Mandela Metropole area. Availability of reliable data is a challenge in real estate studies in South Africa. This study integrates several publicly available resources for the purposes of constructing a statistical model. A model is constructed based on a forward variable selection routine using selection criteria. The resulting model shows six highly significant variables that can be used for modelling purposes. The resulting model is used to make comparisons in the value of the geographical location.
- Full Text:
- Date Issued: 2012