Sensitivity of different areas of the flexor aspect of the human forearm to corticosteroid-induced skin blanching
- Meyer, Eric, Smith, Eric W, Haigh, John M
- Authors: Meyer, Eric , Smith, Eric W , Haigh, John M
- Date: 1992
- Language: English
- Type: Article
- Identifier: vital:6394 , http://hdl.handle.net/10962/d1006317
- Description: The intensity of corticosteroid-induced blanching has been found to vary at different areas of the flexor aspect of the human forearm. A retrospective analysis of 38,880 observations of skin blanching in 56 volunteers was conducted to assess the sensitivity of forearm skin to betamethasone 17-valerate. The mid-forearm appears to be more sensitive to the blanching response than do the areas close to the wrist or elbow. These results indicate that each preparation under evaluation should be applied to several sites along the forearm when using the human skin blanching assay in order to obtain an accurate comparative assessment of corticosteroid release from topical delivery vehicles.
- Full Text: false
- Date Issued: 1992
- Authors: Meyer, Eric , Smith, Eric W , Haigh, John M
- Date: 1992
- Language: English
- Type: Article
- Identifier: vital:6394 , http://hdl.handle.net/10962/d1006317
- Description: The intensity of corticosteroid-induced blanching has been found to vary at different areas of the flexor aspect of the human forearm. A retrospective analysis of 38,880 observations of skin blanching in 56 volunteers was conducted to assess the sensitivity of forearm skin to betamethasone 17-valerate. The mid-forearm appears to be more sensitive to the blanching response than do the areas close to the wrist or elbow. These results indicate that each preparation under evaluation should be applied to several sites along the forearm when using the human skin blanching assay in order to obtain an accurate comparative assessment of corticosteroid release from topical delivery vehicles.
- Full Text: false
- Date Issued: 1992
Eric Nomvete
- Authors: Nomvete, Eric
- Date: 19--?
- Subjects: uncatalogued
- Type: Image
- Identifier: http://hdl.handle.net/10962/126813 , vital:35925 , RHPC-094
- Description: Eric Nomvete. , Use of this resource is governed by the terms and conditions of the Creative Commons "Attribution-NonCommercial-ShareAlike" License (http://creativecommons.org/licenses/by-nc-sa/2.0/)
- Full Text: false
- Date Issued: 19--?
- Authors: Nomvete, Eric
- Date: 19--?
- Subjects: uncatalogued
- Type: Image
- Identifier: http://hdl.handle.net/10962/126813 , vital:35925 , RHPC-094
- Description: Eric Nomvete. , Use of this resource is governed by the terms and conditions of the Creative Commons "Attribution-NonCommercial-ShareAlike" License (http://creativecommons.org/licenses/by-nc-sa/2.0/)
- Full Text: false
- Date Issued: 19--?
Evaluation of the proposed FDA pilot-dose response methodology for topical corticosteroid bioeqivalence testing [authors' reply in Letters to the Editor]
- Smith, Eric W, Walker, Roderick B, Haigh, John M, Kanfer, Isadore
- Authors: Smith, Eric W , Walker, Roderick B , Haigh, John M , Kanfer, Isadore
- Date: 1998
- Language: English
- Type: text , Article
- Identifier: vital:6423 , http://hdl.handle.net/10962/d1006558
- Description: Reply to: Letter to the Editor by Singh GJ; Fleischer N; Lesko L; Williams R - relating to original article in Pharmaceutical Research (USA), Mar 1997, vol. 14, pp. 303-308.
- Full Text: false
- Date Issued: 1998
- Authors: Smith, Eric W , Walker, Roderick B , Haigh, John M , Kanfer, Isadore
- Date: 1998
- Language: English
- Type: text , Article
- Identifier: vital:6423 , http://hdl.handle.net/10962/d1006558
- Description: Reply to: Letter to the Editor by Singh GJ; Fleischer N; Lesko L; Williams R - relating to original article in Pharmaceutical Research (USA), Mar 1997, vol. 14, pp. 303-308.
- Full Text: false
- Date Issued: 1998
The requirements for accurate analysis of pharmaceutical research at South African Universities
- Haigh, John M, Smith, Eric W
- Authors: Haigh, John M , Smith, Eric W
- Date: 1998
- Language: English
- Type: text , Article
- Identifier: vital:6367 , http://hdl.handle.net/10962/d1006067
- Description: International Pharmaceutical Abstracts is a valuable database for pharmaceutical research, although the multisiciplinary nature of this field implies that the database should only be the starting point of a search. This database is totally inappropriate for comparing outputs of individual pharmacy teaching institutions.
- Full Text:
- Date Issued: 1998
- Authors: Haigh, John M , Smith, Eric W
- Date: 1998
- Language: English
- Type: text , Article
- Identifier: vital:6367 , http://hdl.handle.net/10962/d1006067
- Description: International Pharmaceutical Abstracts is a valuable database for pharmaceutical research, although the multisiciplinary nature of this field implies that the database should only be the starting point of a search. This database is totally inappropriate for comparing outputs of individual pharmacy teaching institutions.
- Full Text:
- Date Issued: 1998
Eric Abbhah, Dean of Westminster with Dorah John Jane watching local women stamping mealies
- Subjects: St. Matthew's College -- Photographs St. Matthew's Mission (Keiskammahoek, South Africa) -- Photographs St. Michael's Mission (Eastern Cape, South Africa) -- Photographs St Matthew's Hospital (Eastern Cape, South Africa) -- Photographs
- Type: Image
- Identifier: http://hdl.handle.net/10962/34403 , vital:24242 , This image is held at the Cory Library for Humanities Research at Rhodes University. For further information contact cory@ru.ac.za. The digitisation of this image was made possible through a generous grant received from the Andrew W. Mellon Foundation 2014-2017 , PIC 5004
- Description: A photograph album showing views of buildings and people at St Michaels and St Matthews Missions in Keiskammahoek, South Africa. The album was donated to Cory Library by Mariaan George of Roeland Street, Cape Town
- Full Text: false
- Subjects: St. Matthew's College -- Photographs St. Matthew's Mission (Keiskammahoek, South Africa) -- Photographs St. Michael's Mission (Eastern Cape, South Africa) -- Photographs St Matthew's Hospital (Eastern Cape, South Africa) -- Photographs
- Type: Image
- Identifier: http://hdl.handle.net/10962/34403 , vital:24242 , This image is held at the Cory Library for Humanities Research at Rhodes University. For further information contact cory@ru.ac.za. The digitisation of this image was made possible through a generous grant received from the Andrew W. Mellon Foundation 2014-2017 , PIC 5004
- Description: A photograph album showing views of buildings and people at St Michaels and St Matthews Missions in Keiskammahoek, South Africa. The album was donated to Cory Library by Mariaan George of Roeland Street, Cape Town
- Full Text: false
Lundi (surname unidentified) and Eric Majola
- Authors: Lundi , Majola, Eric
- Date: 19--?
- Subjects: uncatalogued
- Type: Image
- Identifier: http://hdl.handle.net/10962/126295 , vital:35872 , RHPC-034
- Description: Lundi, guitarist for Afri Rhythm Crotchets and Eric Majola, Springbok rugby player. , Use of this resource is governed by the terms and conditions of the Creative Commons "Attribution-NonCommercial-ShareAlike" License (http://creativecommons.org/licenses/by-nc-sa/2.0/)
- Full Text: false
- Date Issued: 19--?
- Authors: Lundi , Majola, Eric
- Date: 19--?
- Subjects: uncatalogued
- Type: Image
- Identifier: http://hdl.handle.net/10962/126295 , vital:35872 , RHPC-034
- Description: Lundi, guitarist for Afri Rhythm Crotchets and Eric Majola, Springbok rugby player. , Use of this resource is governed by the terms and conditions of the Creative Commons "Attribution-NonCommercial-ShareAlike" License (http://creativecommons.org/licenses/by-nc-sa/2.0/)
- Full Text: false
- Date Issued: 19--?
On the study of the performance of Photovoltaic power plants
- Authors: Serameng, Tshepo Joba
- Date: 2019
- Subjects: Photovoltaic power generation , Solar energy Power resources Renewable energy sources
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10948/43401 , vital:36873
- Description: Performance monitoring of different module technologies and system configurations of photovoltaic (PV) systems in South Africa is rare, resulting in-few reports being published based on field results of PV systems installed and operated in South Africa. The goal of this work was to analyse and report on the performance of PV systems by evaluating the energy output of various PV system configurations and module technologies in the central part of South African (southern hemisphere) climatic conditions. To achieve this, a 400 kWp PV Solar plant has been installed and monitored since January 2015 at the Eskom Research and Innovation Centre (ERIC) in Rosherville, Gauteng (26°5'5" South, 28°5 8'1" East and 1625 m above mean sea level). The ERIC plant consists of multi-crystalline silicon (mc-Si) and copper indium gallium selenide (CIGS) thin-film technologies. The plant comprises of two 25° fixed-tilt north facing arrays, two east-west single axis tracking arrays and two 10° fixed shed orientation (East and West) for both module technologies and one north-south single axis tracking for mc-Si. The evaluation was achieved by studying the operation of the PV plant under different weather conditions and the impact of different configurations and technologies by analysing mainly in terms of specific yields normalized per m2 (kWh/kWp/m2). The first part of the study investigates the impact on the overall performance of different PV technologies as a function of the module mounting configuration. The second part presents the PVSyst yield validation for the Eskom Research and Innovation Centre (ERIC) solar PV plant. Normalised yield production calculations were performed for a fair comparison of various configurations. Although CIGS technology has a higher specific yield throughout the year, the normalised yield production per m2 shows that mc-Si technology out-performs CIGS in both fixed north facing and east-west tracking configurations. This study provides an insight to identify the optimal configuration and will also give an indication of suitability of PV technology for deployment in the central part of South Africa, once all design parameters are considered. This information is also useful in evaluating the operational benefits of the plant based on the net energy output. The monitored data and operating experience of the reported PV system can be applied for future projects. It is common at the beginning of any project for photovoltaic (PV) simulation tools to be utilized for yield prediction in order to estimate performance that can be expected. The purpose for PVSyst yield validation in this study was to validate the accuracy of the original PVSyst simulation that were performed using the satellite derived data, PVGIS satellite database for the ERIC PV plant. The validation is done using the actual ground measured solar resource datasets on site by importing them into PVSyst. A brief analysis of the results suggests that the PVSyst model seems to overestimate the yield output relative to the measured values. This due to out-door conditions and environmental factors impacting the PV site. These factors include power outages, module degradation and were unknown during the development phases when original simulations were performed. However, based on the statistical criteria and assessment, it can be concluded that the original PVSyst simulation results are accurate enough as per the MBE and RMSE percentages, however it is noted as well that the modified PVSyst results are more correlated to the measured results in comparison.
- Full Text:
- Date Issued: 2019
- Authors: Serameng, Tshepo Joba
- Date: 2019
- Subjects: Photovoltaic power generation , Solar energy Power resources Renewable energy sources
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10948/43401 , vital:36873
- Description: Performance monitoring of different module technologies and system configurations of photovoltaic (PV) systems in South Africa is rare, resulting in-few reports being published based on field results of PV systems installed and operated in South Africa. The goal of this work was to analyse and report on the performance of PV systems by evaluating the energy output of various PV system configurations and module technologies in the central part of South African (southern hemisphere) climatic conditions. To achieve this, a 400 kWp PV Solar plant has been installed and monitored since January 2015 at the Eskom Research and Innovation Centre (ERIC) in Rosherville, Gauteng (26°5'5" South, 28°5 8'1" East and 1625 m above mean sea level). The ERIC plant consists of multi-crystalline silicon (mc-Si) and copper indium gallium selenide (CIGS) thin-film technologies. The plant comprises of two 25° fixed-tilt north facing arrays, two east-west single axis tracking arrays and two 10° fixed shed orientation (East and West) for both module technologies and one north-south single axis tracking for mc-Si. The evaluation was achieved by studying the operation of the PV plant under different weather conditions and the impact of different configurations and technologies by analysing mainly in terms of specific yields normalized per m2 (kWh/kWp/m2). The first part of the study investigates the impact on the overall performance of different PV technologies as a function of the module mounting configuration. The second part presents the PVSyst yield validation for the Eskom Research and Innovation Centre (ERIC) solar PV plant. Normalised yield production calculations were performed for a fair comparison of various configurations. Although CIGS technology has a higher specific yield throughout the year, the normalised yield production per m2 shows that mc-Si technology out-performs CIGS in both fixed north facing and east-west tracking configurations. This study provides an insight to identify the optimal configuration and will also give an indication of suitability of PV technology for deployment in the central part of South Africa, once all design parameters are considered. This information is also useful in evaluating the operational benefits of the plant based on the net energy output. The monitored data and operating experience of the reported PV system can be applied for future projects. It is common at the beginning of any project for photovoltaic (PV) simulation tools to be utilized for yield prediction in order to estimate performance that can be expected. The purpose for PVSyst yield validation in this study was to validate the accuracy of the original PVSyst simulation that were performed using the satellite derived data, PVGIS satellite database for the ERIC PV plant. The validation is done using the actual ground measured solar resource datasets on site by importing them into PVSyst. A brief analysis of the results suggests that the PVSyst model seems to overestimate the yield output relative to the measured values. This due to out-door conditions and environmental factors impacting the PV site. These factors include power outages, module degradation and were unknown during the development phases when original simulations were performed. However, based on the statistical criteria and assessment, it can be concluded that the original PVSyst simulation results are accurate enough as per the MBE and RMSE percentages, however it is noted as well that the modified PVSyst results are more correlated to the measured results in comparison.
- Full Text:
- Date Issued: 2019
In vitro diffusion cell design and validation. II. Temperature, agitation and membrane effects on betamethasone 17-valerate permeation
- Smith, Eric W, Haigh, John M
- Authors: Smith, Eric W , Haigh, John M
- Date: 1992
- Language: English
- Type: text , Article
- Identifier: vital:6422 , http://hdl.handle.net/10962/d1006557
- Description: An in vitro permeation cell has been designed and validated for use in monitoring the transmembrane permeation of betamethasone 17-valerate. The design utilizes common laboratory equipment and incorporates as many beneficial features as possible from other designs. The importance of fully validating the hydrodynamic performance of the cell prior to experimentation is stressed. The cell was validated by monitoring the diffusion of betamethasone 17-valerate in isopropyl myristate solution into purified isopropyl myristate receptor phase at different temperatures, different agitation rates and through different synthetic and biological membranes. The results of the hydrodynamic validation agree with data from other researchers and show that the permeation cell is adequately sensitive to these experimental parameters. The results of the membrane evaluation allow appropriate selection of the barrier material for representative transdermal experiments to be conducted. While human and porcine stratum corneum/epidermis are similar in diffusive properties, hairless mouse skin appears to be the most convenient animal membrane for these studies. Although silicone and cellulose membranes appear to be useful in this application, porous filter membranes and egg-shell membranes are insufficiently discriminatory to betamethasone 17-valerate diffusion to provide useful in vitro permeation data.
- Full Text: false
- Date Issued: 1992
- Authors: Smith, Eric W , Haigh, John M
- Date: 1992
- Language: English
- Type: text , Article
- Identifier: vital:6422 , http://hdl.handle.net/10962/d1006557
- Description: An in vitro permeation cell has been designed and validated for use in monitoring the transmembrane permeation of betamethasone 17-valerate. The design utilizes common laboratory equipment and incorporates as many beneficial features as possible from other designs. The importance of fully validating the hydrodynamic performance of the cell prior to experimentation is stressed. The cell was validated by monitoring the diffusion of betamethasone 17-valerate in isopropyl myristate solution into purified isopropyl myristate receptor phase at different temperatures, different agitation rates and through different synthetic and biological membranes. The results of the hydrodynamic validation agree with data from other researchers and show that the permeation cell is adequately sensitive to these experimental parameters. The results of the membrane evaluation allow appropriate selection of the barrier material for representative transdermal experiments to be conducted. While human and porcine stratum corneum/epidermis are similar in diffusive properties, hairless mouse skin appears to be the most convenient animal membrane for these studies. Although silicone and cellulose membranes appear to be useful in this application, porous filter membranes and egg-shell membranes are insufficiently discriminatory to betamethasone 17-valerate diffusion to provide useful in vitro permeation data.
- Full Text: false
- Date Issued: 1992
Nani Bwabongo
- Priscilia Ngando (lead vocal), Mevio-Mayo, Dany Mouanga, Mouasso (rhythm guitars), Aubin Sandjo, Scorpionkabambay, Mouche Bass (bass guitar), Dany Mouanga, Eric Sefu (solo guitar), Aubin Sandjo, Paul Balong (keyboard), Abel Massock, Fabo Claude, Nono (chorus), Cyrille Baudoin Koudh (composer), Aubin Sandjo (drum, percussion, keyboard), Alhadji Mallam Issa (talking drum), Moussa Haissam
- Authors: Priscilia Ngando (lead vocal) , Mevio-Mayo, Dany Mouanga, Mouasso (rhythm guitars) , Aubin Sandjo, Scorpionkabambay, Mouche Bass (bass guitar) , Dany Mouanga, Eric Sefu (solo guitar) , Aubin Sandjo, Paul Balong (keyboard) , Abel Massock, Fabo Claude, Nono (chorus) , Cyrille Baudoin Koudh (composer) , Aubin Sandjo (drum, percussion, keyboard) , Alhadji Mallam Issa (talking drum) , Moussa Haissam
- Date: 2000
- Subjects: Popular music , Popular music--Africa, West , Africa Cameroon Yaounde f-cm
- Language: French
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/130792 , vital:36479 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDC47-02
- Description: Popular songs from Cameroon, featuring female vocal accompanied by keyboard, chorus, guitar, percussion and talking drum, playing West and Central African rhythms
- Full Text: false
- Date Issued: 2000
- Authors: Priscilia Ngando (lead vocal) , Mevio-Mayo, Dany Mouanga, Mouasso (rhythm guitars) , Aubin Sandjo, Scorpionkabambay, Mouche Bass (bass guitar) , Dany Mouanga, Eric Sefu (solo guitar) , Aubin Sandjo, Paul Balong (keyboard) , Abel Massock, Fabo Claude, Nono (chorus) , Cyrille Baudoin Koudh (composer) , Aubin Sandjo (drum, percussion, keyboard) , Alhadji Mallam Issa (talking drum) , Moussa Haissam
- Date: 2000
- Subjects: Popular music , Popular music--Africa, West , Africa Cameroon Yaounde f-cm
- Language: French
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/130792 , vital:36479 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDC47-02
- Description: Popular songs from Cameroon, featuring female vocal accompanied by keyboard, chorus, guitar, percussion and talking drum, playing West and Central African rhythms
- Full Text: false
- Date Issued: 2000
Dikalo
- Priscilia Ngando (lead vocal), Mevio-Mayo, Dany Mouanga, Mouasso (rhythm guitars), Aubin Sandjo, Scorpionkabambay, Mouche Bass (bass guitar), Dany Mouanga, Eric Sefu (solo guitar), Aubin Sandjo, Paul Balong (keyboard), Abel Massock, Fabo Claude, Nono (chorus), Priscilia Ngando (composer), Aubin Sandjo (drum, percussion, keyboard), Alhadji Mallam Issa (talking drum), Moussa Haissam
- Authors: Priscilia Ngando (lead vocal) , Mevio-Mayo, Dany Mouanga, Mouasso (rhythm guitars) , Aubin Sandjo, Scorpionkabambay, Mouche Bass (bass guitar) , Dany Mouanga, Eric Sefu (solo guitar) , Aubin Sandjo, Paul Balong (keyboard) , Abel Massock, Fabo Claude, Nono (chorus) , Priscilia Ngando (composer) , Aubin Sandjo (drum, percussion, keyboard) , Alhadji Mallam Issa (talking drum) , Moussa Haissam
- Date: 2000
- Subjects: Popular music , Popular music--Africa, West , Africa Cameroon Yaounde f-cm
- Language: French
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/130836 , vital:36486 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDC47-03
- Description: Popular songs from Cameroon, featuring female vocal accompanied by keyboard, chorus, guitar, percussion and talking drum, playing West and Central African rhythms
- Full Text: false
- Date Issued: 2000
- Authors: Priscilia Ngando (lead vocal) , Mevio-Mayo, Dany Mouanga, Mouasso (rhythm guitars) , Aubin Sandjo, Scorpionkabambay, Mouche Bass (bass guitar) , Dany Mouanga, Eric Sefu (solo guitar) , Aubin Sandjo, Paul Balong (keyboard) , Abel Massock, Fabo Claude, Nono (chorus) , Priscilia Ngando (composer) , Aubin Sandjo (drum, percussion, keyboard) , Alhadji Mallam Issa (talking drum) , Moussa Haissam
- Date: 2000
- Subjects: Popular music , Popular music--Africa, West , Africa Cameroon Yaounde f-cm
- Language: French
- Type: sound recordings , field recordings , sound recording-musical
- Identifier: http://hdl.handle.net/10962/130836 , vital:36486 , International Library of African Music, Rhodes University, Grahamstown, South Africa , SDC47-03
- Description: Popular songs from Cameroon, featuring female vocal accompanied by keyboard, chorus, guitar, percussion and talking drum, playing West and Central African rhythms
- Full Text: false
- Date Issued: 2000
New placoderm fishes from the Late Devonian of South Africa
- Long, John A, Anderson, M Eric, Gess, Robert W, Hiller, Norton
- Authors: Long, John A , Anderson, M Eric , Gess, Robert W , Hiller, Norton
- Date: 1997
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/72763 , vital:30108 , https://doi.org/10.1080/02724634.1997.10010973
- Description: New placoderm fishes are described from a black shale lens in the Famennian Witpoort Formation, near Grahamstown, South Africa. Arthrodires include a new species of Groenlandaspis, G. riniensis sp. nov., a new genus of groenlandaspidid, Africanaspis doryssa gen. et sp. nov., and a new species of the antiarch Bothriolepis, B. africana sp. nov. This is the first record of the ubiquitous genera Bothriolepis and Groenlandaspis from the African continent. The South African placoderm fauna has demonstrable links with the eastern Gondwana faunas in the close affinity of the Bothriolepis africana with B. barred of Antarctica, and the high diversity of groenlandaspid species, especially the presence of a very high crested form having affinities to Tiaraspis.
- Full Text: false
- Date Issued: 1997
- Authors: Long, John A , Anderson, M Eric , Gess, Robert W , Hiller, Norton
- Date: 1997
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/72763 , vital:30108 , https://doi.org/10.1080/02724634.1997.10010973
- Description: New placoderm fishes are described from a black shale lens in the Famennian Witpoort Formation, near Grahamstown, South Africa. Arthrodires include a new species of Groenlandaspis, G. riniensis sp. nov., a new genus of groenlandaspidid, Africanaspis doryssa gen. et sp. nov., and a new species of the antiarch Bothriolepis, B. africana sp. nov. This is the first record of the ubiquitous genera Bothriolepis and Groenlandaspis from the African continent. The South African placoderm fauna has demonstrable links with the eastern Gondwana faunas in the close affinity of the Bothriolepis africana with B. barred of Antarctica, and the high diversity of groenlandaspid species, especially the presence of a very high crested form having affinities to Tiaraspis.
- Full Text: false
- Date Issued: 1997
The Diaz Cross at Boknes
- Authors: Reynolds, Rex
- Subjects: Butler, Guy, 1918-2001 Diaz Cross Alexandria (South Africa) -- History Boknes (South Africa) -- History
- Type: Image
- Identifier: http://hdl.handle.net/10962/9704 , vital:21522 , This image is held at the Cory Library for Humanities Research at Rhodes University. For further information contact cory@ru.ac.za. The digitisation of this image was made possible through a generous grant received from the Andrew W. Mellon Foundation 2014-2017. , PIC/M 5259
- Description: The Diaz Cross Memorial at Kwaaihoek is one of three crosses erected by Bartholmew Diaz when he navigated the Cape coast in the fifteenth century, on his epic journey seeking a route to India, with a squadron of three ships, two caravels and a square-rigged store ship. The original cross was erected 12 March 1488, and was replaced by a replica. The original Diaz cross is in in the William Cullen Library at the University of the Witwatersrand in Johannesburg. This cross was originally thought to have been erected on an island off the coast of present day Port Elizabeth, however it was discovered by Professor Eric Axelson on the coast near the Alexandria dune fields in 1937. The other two crosses are to be found in Cape Town and at Mossel Bay's Market Square. Diaz Cross is about a 3km-walk from Boknes and about 6km from Bushman's River Mouth. , F G Butler (donor)
- Full Text: false
- Authors: Reynolds, Rex
- Subjects: Butler, Guy, 1918-2001 Diaz Cross Alexandria (South Africa) -- History Boknes (South Africa) -- History
- Type: Image
- Identifier: http://hdl.handle.net/10962/9704 , vital:21522 , This image is held at the Cory Library for Humanities Research at Rhodes University. For further information contact cory@ru.ac.za. The digitisation of this image was made possible through a generous grant received from the Andrew W. Mellon Foundation 2014-2017. , PIC/M 5259
- Description: The Diaz Cross Memorial at Kwaaihoek is one of three crosses erected by Bartholmew Diaz when he navigated the Cape coast in the fifteenth century, on his epic journey seeking a route to India, with a squadron of three ships, two caravels and a square-rigged store ship. The original cross was erected 12 March 1488, and was replaced by a replica. The original Diaz cross is in in the William Cullen Library at the University of the Witwatersrand in Johannesburg. This cross was originally thought to have been erected on an island off the coast of present day Port Elizabeth, however it was discovered by Professor Eric Axelson on the coast near the Alexandria dune fields in 1937. The other two crosses are to be found in Cape Town and at Mossel Bay's Market Square. Diaz Cross is about a 3km-walk from Boknes and about 6km from Bushman's River Mouth. , F G Butler (donor)
- Full Text: false
Dr Eric with Church Moderator Mr Gwali
- Dr Eric and Mr William Gwali
- Authors: Dr Eric and Mr William Gwali
- Date: 2016
- Subjects: UNCATALOGUED
- Type: Image
- Identifier: http://hdl.handle.net/10962/220175 , vital:48599 , KHP-200
- Description: After Church Service Interview of Church Commitee , Use of this resource is governed by the terms and conditions of the Creative Commons "Attribution-NonCommercial-ShareAlike" License (http://creativecommons.org/licenses/by-nc-sa/2.0/) (NEVER CAHNGE THIS FIELD)
- Full Text: false
- Date Issued: 2016
- Authors: Dr Eric and Mr William Gwali
- Date: 2016
- Subjects: UNCATALOGUED
- Type: Image
- Identifier: http://hdl.handle.net/10962/220175 , vital:48599 , KHP-200
- Description: After Church Service Interview of Church Commitee , Use of this resource is governed by the terms and conditions of the Creative Commons "Attribution-NonCommercial-ShareAlike" License (http://creativecommons.org/licenses/by-nc-sa/2.0/) (NEVER CAHNGE THIS FIELD)
- Full Text: false
- Date Issued: 2016
Analysis of chromameter results obtained from corticosteroid-induced skin blanching. I. Manipulation of data
- Smith, Eric W, Haigh, John M, Walker, Roderick B
- Authors: Smith, Eric W , Haigh, John M , Walker, Roderick B
- Date: 1998
- Language: English
- Type: text , Article
- Identifier: vital:6424 , http://hdl.handle.net/10962/d1006559
- Description: Purpose. One of the unresolved issues in the FDA Guidance document for topical corticosteroid bioequivalence testing is the method of manipulation suggested for the chromameter data. The purpose of this study was to manipulate the instrumental data from a typical blanching study in a number of ways to investigate the appropriateness of these procedures for comparison with the subjective visually-assessed results. Methods. The human skin blanching assay methodology routinely practiced in our laboratories was utilised and the vasoconstriction produced by two corticosteroid formulations of different potency was assessed visually and instrumentally by use of a Minolta chromameter. The instrumental data were corrected for zero-time and unmedicated site readings. In addition, Euclidean distances were calculated using all data generated by the instrument. Results. Individually the a-, b- and L-scale chromameter values are imprecise and there is negligible vasoconstriction response recorded for the moderately potent formulation. Arithmetical manipulation of the data as suggested by the FDA does not appear to improve the quality of the data in any way. Euclidean distance analysis more closely resembles the visual data and appears to have better precision. Conclusions. It is clear that mathematical correction of chromameter data is unnecessary, especially since the instrumental data are extremely imprecise. Furthermore, the assessment of each individual chromameter index does not adequately characterise the blanching response profile. It is therefore suggested that Euclidean distance may be a better measure on which to base an analysis of bioequivalence than the truncated data set methodology currently suggested by the FDA.
- Full Text: false
- Date Issued: 1998
- Authors: Smith, Eric W , Haigh, John M , Walker, Roderick B
- Date: 1998
- Language: English
- Type: text , Article
- Identifier: vital:6424 , http://hdl.handle.net/10962/d1006559
- Description: Purpose. One of the unresolved issues in the FDA Guidance document for topical corticosteroid bioequivalence testing is the method of manipulation suggested for the chromameter data. The purpose of this study was to manipulate the instrumental data from a typical blanching study in a number of ways to investigate the appropriateness of these procedures for comparison with the subjective visually-assessed results. Methods. The human skin blanching assay methodology routinely practiced in our laboratories was utilised and the vasoconstriction produced by two corticosteroid formulations of different potency was assessed visually and instrumentally by use of a Minolta chromameter. The instrumental data were corrected for zero-time and unmedicated site readings. In addition, Euclidean distances were calculated using all data generated by the instrument. Results. Individually the a-, b- and L-scale chromameter values are imprecise and there is negligible vasoconstriction response recorded for the moderately potent formulation. Arithmetical manipulation of the data as suggested by the FDA does not appear to improve the quality of the data in any way. Euclidean distance analysis more closely resembles the visual data and appears to have better precision. Conclusions. It is clear that mathematical correction of chromameter data is unnecessary, especially since the instrumental data are extremely imprecise. Furthermore, the assessment of each individual chromameter index does not adequately characterise the blanching response profile. It is therefore suggested that Euclidean distance may be a better measure on which to base an analysis of bioequivalence than the truncated data set methodology currently suggested by the FDA.
- Full Text: false
- Date Issued: 1998
Effect of concentration and degree of saturation of topical fluocinonide formulations on in vitro membrane transport and in vivo availability on human skin
- Schwarb, Fabian P, Imanidis, Georgios, Smith, Eric W, Haigh, John M, Surber, Christian
- Authors: Schwarb, Fabian P , Imanidis, Georgios , Smith, Eric W , Haigh, John M , Surber, Christian
- Date: 1999
- Language: English
- Type: text , Article
- Identifier: vital:6425 , http://hdl.handle.net/10962/d1006560
- Description: Purpose. The thermodynamic acitvity of drugs in topical vehicles is considered to significantly influence topical delivery. In vitro diffusion across a synthetic membrane was shown to be correlated to the degree of saturation of the drug in the applied vehicle and therefore offers a potential for increased topical drug delivery. Fluocinonide a topical corticosteroid, was chosen as a model compound to investigate in vitro and in vivo availability from formulations with different degrees of saturation. Methods. Sub-, as well as, supersaturated drug solutions were prepared using PVP as an antinucleant agent. In vitro membrane diffusion experiments across silicone membrane and in vivo pharmacodynamic activity assessments, using the human skin blanching assay, were carried out. Results. Over the concentration range studied, the in vitro membrane transport of fluocinonide was proportional to the degree of saturation of the respective formulations. The in vivo pharmacodynamic response in the human skin blanching assay was related to the concentration of the drug in the vehicle irrespective of the degree of saturation. Conclusions. From the membrane permeation experiment it can be concluded, that the drug flux might be increased supra-proportionally with increasing donor concentration, drug (super-)saturation (proportional), beyond what would be anticipated based on ideal donor concentration and partition coefficient considerations only. These findings could not be confirmed in the in vivo investigation, probably due to additional vehicle effects (e.g., enhancement, irritation, drug binding) which have to be expected and could have altered the integrity of the stratum corneum and therewith topical bioavailability of the drug.
- Full Text: false
- Date Issued: 1999
- Authors: Schwarb, Fabian P , Imanidis, Georgios , Smith, Eric W , Haigh, John M , Surber, Christian
- Date: 1999
- Language: English
- Type: text , Article
- Identifier: vital:6425 , http://hdl.handle.net/10962/d1006560
- Description: Purpose. The thermodynamic acitvity of drugs in topical vehicles is considered to significantly influence topical delivery. In vitro diffusion across a synthetic membrane was shown to be correlated to the degree of saturation of the drug in the applied vehicle and therefore offers a potential for increased topical drug delivery. Fluocinonide a topical corticosteroid, was chosen as a model compound to investigate in vitro and in vivo availability from formulations with different degrees of saturation. Methods. Sub-, as well as, supersaturated drug solutions were prepared using PVP as an antinucleant agent. In vitro membrane diffusion experiments across silicone membrane and in vivo pharmacodynamic activity assessments, using the human skin blanching assay, were carried out. Results. Over the concentration range studied, the in vitro membrane transport of fluocinonide was proportional to the degree of saturation of the respective formulations. The in vivo pharmacodynamic response in the human skin blanching assay was related to the concentration of the drug in the vehicle irrespective of the degree of saturation. Conclusions. From the membrane permeation experiment it can be concluded, that the drug flux might be increased supra-proportionally with increasing donor concentration, drug (super-)saturation (proportional), beyond what would be anticipated based on ideal donor concentration and partition coefficient considerations only. These findings could not be confirmed in the in vivo investigation, probably due to additional vehicle effects (e.g., enhancement, irritation, drug binding) which have to be expected and could have altered the integrity of the stratum corneum and therewith topical bioavailability of the drug.
- Full Text: false
- Date Issued: 1999
The first Bothriolepsis-associated Devonian fish fauna from Africa
- Anderson, M Eric, Hiller, Norton, Gess, Robert W
- Authors: Anderson, M Eric , Hiller, Norton , Gess, Robert W
- Date: 1994
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/73852 , vital:30235 , https://journals.co.za/content/sajsci/90/7/AJA00382353_5900
- Description: An advanced diplacanthid (Climatiiformes) is described from a Famennian estuarine environment of South Africa. It is characterized by having exceptionally long thin fin spines and a deep body form. Unusual details of the fins and fin spine insertions are preserved. This is the first record of a diplacanthid from the Southern Hemisphere.
- Full Text:
- Date Issued: 1994
- Authors: Anderson, M Eric , Hiller, Norton , Gess, Robert W
- Date: 1994
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/73852 , vital:30235 , https://journals.co.za/content/sajsci/90/7/AJA00382353_5900
- Description: An advanced diplacanthid (Climatiiformes) is described from a Famennian estuarine environment of South Africa. It is characterized by having exceptionally long thin fin spines and a deep body form. Unusual details of the fins and fin spine insertions are preserved. This is the first record of a diplacanthid from the Southern Hemisphere.
- Full Text:
- Date Issued: 1994
Condolence letter to Sheila Burnett from Rev. Eric Pike
- Date: 1994-09-01
- Subjects: Burnett, Bill Bendyshe -- 1917-1994 Condolence notes Burnett family
- Type: Image
- Identifier: http://hdl.handle.net/10962/21406 , vital:22933 , This image is held at the Cory Library for Humanities Research at Rhodes University. For further information contact cory@ru.ac.za. The digitisation of this image was made possible through a generous grant received from the Andrew W. Mellon Foundation 2014-2017. , MS 20 0037
- Description: This collection contains the letters of condolences, addressed to Sheila Burnett on the death of her husband Bill Bendyshe Burnett, who died on the 23rd of August 1994.
- Full Text:
- Date Issued: 1994-09-01
- Date: 1994-09-01
- Subjects: Burnett, Bill Bendyshe -- 1917-1994 Condolence notes Burnett family
- Type: Image
- Identifier: http://hdl.handle.net/10962/21406 , vital:22933 , This image is held at the Cory Library for Humanities Research at Rhodes University. For further information contact cory@ru.ac.za. The digitisation of this image was made possible through a generous grant received from the Andrew W. Mellon Foundation 2014-2017. , MS 20 0037
- Description: This collection contains the letters of condolences, addressed to Sheila Burnett on the death of her husband Bill Bendyshe Burnett, who died on the 23rd of August 1994.
- Full Text:
- Date Issued: 1994-09-01
Accuracy and reproducibility of the multiple-reading skin blanching assay
- Smith, Eric W, Meyer, Eric, Haigh, John M
- Authors: Smith, Eric W , Meyer, Eric , Haigh, John M
- Date: 1992
- Language: English
- Type: Book chapter
- Identifier: vital:6439 , http://hdl.handle.net/10962/d1006625
- Full Text:
- Date Issued: 1992
- Authors: Smith, Eric W , Meyer, Eric , Haigh, John M
- Date: 1992
- Language: English
- Type: Book chapter
- Identifier: vital:6439 , http://hdl.handle.net/10962/d1006625
- Full Text:
- Date Issued: 1992
Bells and bell ringers in South Africa, 1835-2000. Part I
- Authors: Lewis, Colin A
- Date: 2001
- Language: English
- Type: Article
- Identifier: vital:6164 , http://hdl.handle.net/10962/d1012352 , http://www.ringingworld.co.uk/
- Description: Colin Lewis was Professor of Geography at Rhodes University, Grahamstown, South Africa from 1989 until his retirement at the end of 2007. In 1990, with the strong support of the incumbent Vice-Chancellor, Dr Derek Henderson, he instigated the Certificate in Change Ringing (Church Bell Ringing) in the Rhodes University Department of Music and Musicology - the first such course to be offered in Africa. Since that date he has lectured in the basic theory, and taught the practice of change ringing. He is the Ringing Master of the Cathedral of St Michael and St George, Grahamstown, South Africa. , The first ring of bells in Africa was installed in Grahamstown Cathedral in 1879 at the instigation of Frederick Henry Williams. Williams was Dean of Grahamstown from 1865 until his death in 1885. He was born in County Fermanagh, Ireland, not far from Enniskillen, where an octave was installed in the Cathedral when Williams was an impressionable 12-year old. Grahamstown's bells were also an octave, cast by John Warner and Sons of London. They were hung in the newly built tower, designed by the English architect, George Gilbert Scott.
- Full Text:
- Date Issued: 2001
- Authors: Lewis, Colin A
- Date: 2001
- Language: English
- Type: Article
- Identifier: vital:6164 , http://hdl.handle.net/10962/d1012352 , http://www.ringingworld.co.uk/
- Description: Colin Lewis was Professor of Geography at Rhodes University, Grahamstown, South Africa from 1989 until his retirement at the end of 2007. In 1990, with the strong support of the incumbent Vice-Chancellor, Dr Derek Henderson, he instigated the Certificate in Change Ringing (Church Bell Ringing) in the Rhodes University Department of Music and Musicology - the first such course to be offered in Africa. Since that date he has lectured in the basic theory, and taught the practice of change ringing. He is the Ringing Master of the Cathedral of St Michael and St George, Grahamstown, South Africa. , The first ring of bells in Africa was installed in Grahamstown Cathedral in 1879 at the instigation of Frederick Henry Williams. Williams was Dean of Grahamstown from 1865 until his death in 1885. He was born in County Fermanagh, Ireland, not far from Enniskillen, where an octave was installed in the Cathedral when Williams was an impressionable 12-year old. Grahamstown's bells were also an octave, cast by John Warner and Sons of London. They were hung in the newly built tower, designed by the English architect, George Gilbert Scott.
- Full Text:
- Date Issued: 2001
Up Beat Issue Number 1 1993
- SACHED
- Authors: SACHED
- Date: 1993
- Subjects: SACHED
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/118646 , vital:34653
- Description: Welcome to Upbeat 1993! A new school year is underway. We all hope that the coming year will bring better things; new friends, an exciting romance, success at school and an end to the violence and uncertain future in our country. We all have it in us to make change to our lives. Listen, learn and ask questions. Don't be left behind because you don't understand. That's the theme of our calendar this year. And it's FREE inside this issue of Upbeat. Our leaders have said that there will be free elections this year. But many people don't know how to vote. Don't be in the dark. Upbeat will be running stories all about voting this year. Don't miss the first article on page 14. For many people the world of computers seems too complicated. In a three part series. Upbeat will tell you all about the exciting world of computers. You could also win a fantastic IBM computer worth R3 000. Discover the world of computers on page 20. And don't miss our great new comic on page 26. Collector of Treasure is a classic African short story by Bessie Flead. It tells the story of Dikeledi, a young woman who lived in a village in Botswana. For many years this story has shocked readers. The comic captures the drama and horror of Dikeledi's remarkable courage. Don't be without Upbeat this year. We've got lots of great new stories lined up. Subscribe or get Upbeat delivered to your school. Find out how to get Upbeat quickly and easily each month, on page 6.
- Full Text:
- Date Issued: 1993
- Authors: SACHED
- Date: 1993
- Subjects: SACHED
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/118646 , vital:34653
- Description: Welcome to Upbeat 1993! A new school year is underway. We all hope that the coming year will bring better things; new friends, an exciting romance, success at school and an end to the violence and uncertain future in our country. We all have it in us to make change to our lives. Listen, learn and ask questions. Don't be left behind because you don't understand. That's the theme of our calendar this year. And it's FREE inside this issue of Upbeat. Our leaders have said that there will be free elections this year. But many people don't know how to vote. Don't be in the dark. Upbeat will be running stories all about voting this year. Don't miss the first article on page 14. For many people the world of computers seems too complicated. In a three part series. Upbeat will tell you all about the exciting world of computers. You could also win a fantastic IBM computer worth R3 000. Discover the world of computers on page 20. And don't miss our great new comic on page 26. Collector of Treasure is a classic African short story by Bessie Flead. It tells the story of Dikeledi, a young woman who lived in a village in Botswana. For many years this story has shocked readers. The comic captures the drama and horror of Dikeledi's remarkable courage. Don't be without Upbeat this year. We've got lots of great new stories lined up. Subscribe or get Upbeat delivered to your school. Find out how to get Upbeat quickly and easily each month, on page 6.
- Full Text:
- Date Issued: 1993