The income tax consequences of the in-house development of software
- Authors: Hodge, Dominic Shaughn
- Date: 2014
- Subjects: Computer software -- Accounting , Income tax -- Data processing , Research and development projects , Income tax -- Law and legislation -- South Africa , Computer software -- Development -- South Africa , Computer software -- Law and legislation -- South Africa
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:910 , http://hdl.handle.net/10962/d1013550
- Description: The objective of this thesis was to explore the nature of expenditure incurred on the internal development of software and its treatment in terms of the accounting and taxation frameworks to which it is subject. In fulfilling the primary objective the thesis had a number of subsidiary considerations. These included, firstly, a brief analysis of the approach of the software industry in South Africa to the taxation treatment of this type of software. The second consideration was a discussion and analysis of the taxation framework which differentiates between capital and revenue and the extent to which the receipts produced by internally developed software may be informative of the nature of the expenditure. The third was an analysis of the deductibility of expenditure incurred in the production of software with the fourth analysing the tests employed in the determination of whether expenditure is capital or revenue in nature. The fifth objective was to briefly analyse the accounting standards which find application in the determination of whether or not the software created can be considered a capital asset. The final subsidiary objective of the thesis was an analysis of the taxation framework applicable to software in respect of research and development incentives, as well as the position in the United States of America. Throughout the thesis the most apparent commonality is that there exists a significant level of uncertainty as to the taxation treatment of software both in South Africa and in America. The research concludes by stating that such uncertainty is prejudicial to the interests of research and development in relation to software.
- Full Text:
- Date Issued: 2014
- Authors: Hodge, Dominic Shaughn
- Date: 2014
- Subjects: Computer software -- Accounting , Income tax -- Data processing , Research and development projects , Income tax -- Law and legislation -- South Africa , Computer software -- Development -- South Africa , Computer software -- Law and legislation -- South Africa
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:910 , http://hdl.handle.net/10962/d1013550
- Description: The objective of this thesis was to explore the nature of expenditure incurred on the internal development of software and its treatment in terms of the accounting and taxation frameworks to which it is subject. In fulfilling the primary objective the thesis had a number of subsidiary considerations. These included, firstly, a brief analysis of the approach of the software industry in South Africa to the taxation treatment of this type of software. The second consideration was a discussion and analysis of the taxation framework which differentiates between capital and revenue and the extent to which the receipts produced by internally developed software may be informative of the nature of the expenditure. The third was an analysis of the deductibility of expenditure incurred in the production of software with the fourth analysing the tests employed in the determination of whether expenditure is capital or revenue in nature. The fifth objective was to briefly analyse the accounting standards which find application in the determination of whether or not the software created can be considered a capital asset. The final subsidiary objective of the thesis was an analysis of the taxation framework applicable to software in respect of research and development incentives, as well as the position in the United States of America. Throughout the thesis the most apparent commonality is that there exists a significant level of uncertainty as to the taxation treatment of software both in South Africa and in America. The research concludes by stating that such uncertainty is prejudicial to the interests of research and development in relation to software.
- Full Text:
- Date Issued: 2014
The income tax implications resulting from the introduction of section 12N of the Income Tax Act
- Authors: Grebe, Alta-Mari
- Date: 2014
- Subjects: Income tax -- Law and legislation -- South Africa , Land tenure -- South Africa , Capital gains tax -- South Africa
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:8966 , http://hdl.handle.net/10948/d1020787
- Description: Section 12N, introduction into the Income Tax Act by way of Taxation Laws Amendment Act and which became effective on 2 November 2010, provides for allowances on the leasehold improvements on government-owned land and land leased from certain tax exempt entities as stipulated in section 10 (1) (cA) and (t). As section 12N deems the lessee to be the owner of the leasehold improvement, the lessee now qualifies for capital allowances which were previously disallowed.
- Full Text:
- Date Issued: 2014
- Authors: Grebe, Alta-Mari
- Date: 2014
- Subjects: Income tax -- Law and legislation -- South Africa , Land tenure -- South Africa , Capital gains tax -- South Africa
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:8966 , http://hdl.handle.net/10948/d1020787
- Description: Section 12N, introduction into the Income Tax Act by way of Taxation Laws Amendment Act and which became effective on 2 November 2010, provides for allowances on the leasehold improvements on government-owned land and land leased from certain tax exempt entities as stipulated in section 10 (1) (cA) and (t). As section 12N deems the lessee to be the owner of the leasehold improvement, the lessee now qualifies for capital allowances which were previously disallowed.
- Full Text:
- Date Issued: 2014
The incurious seeker: waiting, and the search for the stranger in the fiction of Samuel Beckett and JM Coetzee
- Authors: Marais, Mike
- Date: 2014
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/143971 , vital:38299 , https://mediatropes.com/index.php/Mediatropes/article/view/22380/18161
- Description: In J.M. Coetzee and the Novel: Writing and Politics after Beckett, Patrick Hayes argues that Coetzee, while influenced by Beckett’s prose style, assimilates it in such a way that his writing not only departs from the latter’s solipsism but also provides “an anti-foundational imagining of moral community” (71). While there is much merit to this argument, Hayes’s distinction between Beckett’s solipsism and Coetzee’s concern with community downplays the extent to which the human subject’s conception of herself depends on the differential process through which community establishes itself. In the first section of this paper I show that, already in Murphy, we find evidence in support of Ileana Marculescu’s argument that Beckett inscribes solipsism in his writing only to subvert it. Murphy’s attempts at solipsistic knowledge fail precisely because he has been estranged from himself by language and community. What appears to be solipsism is, in fact, a search for the self from which he has been divided by community. In Beckett’s writing, the self’s concern with its ability to know itself is always a concern with community.
- Full Text:
- Date Issued: 2014
- Authors: Marais, Mike
- Date: 2014
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/143971 , vital:38299 , https://mediatropes.com/index.php/Mediatropes/article/view/22380/18161
- Description: In J.M. Coetzee and the Novel: Writing and Politics after Beckett, Patrick Hayes argues that Coetzee, while influenced by Beckett’s prose style, assimilates it in such a way that his writing not only departs from the latter’s solipsism but also provides “an anti-foundational imagining of moral community” (71). While there is much merit to this argument, Hayes’s distinction between Beckett’s solipsism and Coetzee’s concern with community downplays the extent to which the human subject’s conception of herself depends on the differential process through which community establishes itself. In the first section of this paper I show that, already in Murphy, we find evidence in support of Ileana Marculescu’s argument that Beckett inscribes solipsism in his writing only to subvert it. Murphy’s attempts at solipsistic knowledge fail precisely because he has been estranged from himself by language and community. What appears to be solipsism is, in fact, a search for the self from which he has been divided by community. In Beckett’s writing, the self’s concern with its ability to know itself is always a concern with community.
- Full Text:
- Date Issued: 2014
The influence of employees's perceptions of organisational ethics and perceived relative self-ethicality on their levels of organisational identification and overall well-being
- Authors: Breytenbach, Nadia
- Date: 2014
- Subjects: Corporate culture , Well-being , Work ethic , Self-realization
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:9411 , http://hdl.handle.net/10948/d1020072
- Description: This study investigated whether an employees’ perception of the ethical culture in the organisation and their perception of their own ethicality influenced their level of organisational identification and additionally, whether this relationship between perceived ethical culture and organisational identification had an influence on workplace wellbeing. The aim of this research study was to measure employees’ perceptions of organisational ethics, their relative self-ethicality, organisational identification, and wellbeing, in order to develop a model pertaining to the relationship between these three constructs. Research showed that employees’ perceptions of the ethical culture in their organisation can influence how they identify with that particular organisation. Research also indicated that the differences between perceived organisational ethicality and relative self-ethicality exist. Additionally, research showed the influence of perceived ethical culture and relative self-ethicality has indicated a relationship between organisational identification and wellbeing respectively. However, to date and to the researcher’s knowledge there has been no investigation of the relationship between these four constructs. This research study was quantitative in nature in which a questionnaire was utilised as a research method. A sample of 111 respondent from three organisations in the automation industry in the Eastern Cape, Port Elizabeth was utilised for this research study. The main findings indicated that an alternative model resulted to be a good fit through structural equation modelling. The results illustrated that organisational ethicality has an influence on how employees identify with their organisations and how this relationship influences wellbeing. Therefore, it is worthwhile to invest in an ethical organisational culture for the sustainability of the organisation and its employees’ livelihoods. This study contributes to the literature based on perceived ethical culture, organisational identification, and workplace wellbeing. Additionally, the study provides readers with a model on how these concepts influence each other.
- Full Text:
- Date Issued: 2014
- Authors: Breytenbach, Nadia
- Date: 2014
- Subjects: Corporate culture , Well-being , Work ethic , Self-realization
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: vital:9411 , http://hdl.handle.net/10948/d1020072
- Description: This study investigated whether an employees’ perception of the ethical culture in the organisation and their perception of their own ethicality influenced their level of organisational identification and additionally, whether this relationship between perceived ethical culture and organisational identification had an influence on workplace wellbeing. The aim of this research study was to measure employees’ perceptions of organisational ethics, their relative self-ethicality, organisational identification, and wellbeing, in order to develop a model pertaining to the relationship between these three constructs. Research showed that employees’ perceptions of the ethical culture in their organisation can influence how they identify with that particular organisation. Research also indicated that the differences between perceived organisational ethicality and relative self-ethicality exist. Additionally, research showed the influence of perceived ethical culture and relative self-ethicality has indicated a relationship between organisational identification and wellbeing respectively. However, to date and to the researcher’s knowledge there has been no investigation of the relationship between these four constructs. This research study was quantitative in nature in which a questionnaire was utilised as a research method. A sample of 111 respondent from three organisations in the automation industry in the Eastern Cape, Port Elizabeth was utilised for this research study. The main findings indicated that an alternative model resulted to be a good fit through structural equation modelling. The results illustrated that organisational ethicality has an influence on how employees identify with their organisations and how this relationship influences wellbeing. Therefore, it is worthwhile to invest in an ethical organisational culture for the sustainability of the organisation and its employees’ livelihoods. This study contributes to the literature based on perceived ethical culture, organisational identification, and workplace wellbeing. Additionally, the study provides readers with a model on how these concepts influence each other.
- Full Text:
- Date Issued: 2014
The influence of family business resources on transgenerational success: a family business case study
- Authors: Klee, Robynne
- Date: 2014
- Subjects: Family-owned business enterprises Family-owned business enterprises -- Succession
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10948/11124 , vital:26887
- Description: Family businesses are major contributors to the economies of most countries and are known to be one of the best performing, most prevalent and resilient forms of business throughout the world. Despite their importance and based on the vast amount of research done in the field of family businesses, this form of business appears to be laden with challenges and is short-lived. Amongst others, one of the most fundamental challenges and contributors to the short-lived nature, and thus high failure rate of family businesses is poor succession planning. In order to address this challenge, the Successful Transgenerational Entrepreneurship Practices (STEP) research framework was developed to ascertain the factors that contribute to entrepreneurial performance and the effective transgenerational potential and success of family businesses globally. Transgenerational potential, entrepreneurial performance, the external mediating factors influencing family businesses, Entrepreneurial Orientation (EO) and the Resource Based View (RBV) of familiness resource pools are the components that make up the STEP research framework. By adopting the STEP research framework, the primary objective of this study is to establish how a transgenerational family business creates new economic activity over time by using and transferring familiness resource pools from one generation to the next. Due to the primary focus of the study being to research familiness resource pools and how they generate transgenerational potential for family businesses, this component of the STEP research framework is investigated in detail. The literature review therefore highlights the eight dimensions of familiness resource pools, namely: leadership, networks, capital, decision-making, culture, relationships, governance and knowledge, and are the main focus of this study. An interpretivism research paradigm is selected for this study. Interpretivism paradigms are associated with qualitative research methodologies. Owing to the fact that much still remains to be discovered in terms of familiness and familiness resource pools, a descriptive, single-case study is the type of research method undertaken. The sample is identified based on non-probability purposive sampling as per the strict guidelines of the STEP project. The sample size in this study consisted of one family business operating in the Eastern Cape, South Africa. The STEP interview schedule, which consists of semi-structured questions, is the research instrument used to collect the necessary data from five participants involved in the family business (a prominent motorcar dealership). Once all the data is collected, a combination of directed content analysis and explanation building are used to analyse the data. The findings of the study reveal that the leadership values present in the family business stem from that of the founder. Contrary to the current CEO’s beliefs that the family business investigated operates primarily under his participative leadership style, the interviews reveal that while the CEO does demonstrate participative leadership, his leadership style is somewhat autocratic in nature. This autocratic leadership style has caused the employees and the business as a whole, to become too reliant on the CEO, especially in terms of strategic decision-making, which may be a threat to the future succession of the business. The CEO’s expert leadership however, ensures that the business adheres to strict guidelines in terms of employing the best person for the job, regardless of whether the candidates are family members or not. As such, the prominent motorcar dealership is marketed as a family business and together under the family leadership, has helped attract customers and well qualified non-family employees to the business. While there is ample leadership available within the business, the lack of succession planning is reiterated to be a major threat facing the future of the business. Almost all of the original networks established by the founder in the prominent motorcar dealership studied still exist in the business in 2014. It is established that employees, especially those in the third generation, are encouraged to build their own networks within their relevant spheres of responsibility. Moreover, the business family’s history, reputation and goodwill have helped create and establish networks for the family business, especially within the Eastern Cape. These networks have helped the business drive sales and have contributed to the success of the business.
- Full Text:
- Date Issued: 2014
- Authors: Klee, Robynne
- Date: 2014
- Subjects: Family-owned business enterprises Family-owned business enterprises -- Succession
- Language: English
- Type: Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10948/11124 , vital:26887
- Description: Family businesses are major contributors to the economies of most countries and are known to be one of the best performing, most prevalent and resilient forms of business throughout the world. Despite their importance and based on the vast amount of research done in the field of family businesses, this form of business appears to be laden with challenges and is short-lived. Amongst others, one of the most fundamental challenges and contributors to the short-lived nature, and thus high failure rate of family businesses is poor succession planning. In order to address this challenge, the Successful Transgenerational Entrepreneurship Practices (STEP) research framework was developed to ascertain the factors that contribute to entrepreneurial performance and the effective transgenerational potential and success of family businesses globally. Transgenerational potential, entrepreneurial performance, the external mediating factors influencing family businesses, Entrepreneurial Orientation (EO) and the Resource Based View (RBV) of familiness resource pools are the components that make up the STEP research framework. By adopting the STEP research framework, the primary objective of this study is to establish how a transgenerational family business creates new economic activity over time by using and transferring familiness resource pools from one generation to the next. Due to the primary focus of the study being to research familiness resource pools and how they generate transgenerational potential for family businesses, this component of the STEP research framework is investigated in detail. The literature review therefore highlights the eight dimensions of familiness resource pools, namely: leadership, networks, capital, decision-making, culture, relationships, governance and knowledge, and are the main focus of this study. An interpretivism research paradigm is selected for this study. Interpretivism paradigms are associated with qualitative research methodologies. Owing to the fact that much still remains to be discovered in terms of familiness and familiness resource pools, a descriptive, single-case study is the type of research method undertaken. The sample is identified based on non-probability purposive sampling as per the strict guidelines of the STEP project. The sample size in this study consisted of one family business operating in the Eastern Cape, South Africa. The STEP interview schedule, which consists of semi-structured questions, is the research instrument used to collect the necessary data from five participants involved in the family business (a prominent motorcar dealership). Once all the data is collected, a combination of directed content analysis and explanation building are used to analyse the data. The findings of the study reveal that the leadership values present in the family business stem from that of the founder. Contrary to the current CEO’s beliefs that the family business investigated operates primarily under his participative leadership style, the interviews reveal that while the CEO does demonstrate participative leadership, his leadership style is somewhat autocratic in nature. This autocratic leadership style has caused the employees and the business as a whole, to become too reliant on the CEO, especially in terms of strategic decision-making, which may be a threat to the future succession of the business. The CEO’s expert leadership however, ensures that the business adheres to strict guidelines in terms of employing the best person for the job, regardless of whether the candidates are family members or not. As such, the prominent motorcar dealership is marketed as a family business and together under the family leadership, has helped attract customers and well qualified non-family employees to the business. While there is ample leadership available within the business, the lack of succession planning is reiterated to be a major threat facing the future of the business. Almost all of the original networks established by the founder in the prominent motorcar dealership studied still exist in the business in 2014. It is established that employees, especially those in the third generation, are encouraged to build their own networks within their relevant spheres of responsibility. Moreover, the business family’s history, reputation and goodwill have helped create and establish networks for the family business, especially within the Eastern Cape. These networks have helped the business drive sales and have contributed to the success of the business.
- Full Text:
- Date Issued: 2014
The influence of gender on access to venture capital and firm performance in small, medium and micro enterprises in King Williams Town, South Africa
- Authors: Shava, Herring
- Date: 2014
- Subjects: Small business -- South Africa -- Eastern Cape , Venture capital -- South Africa -- Eastern Cape , Entrepreneurship -- South Africa -- Eastern Cape , Sex discrimination -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , M Com (Business Management)
- Identifier: http://hdl.handle.net/10353/767 , vital:26495 , Small business -- South Africa -- Eastern Cape , Venture capital -- South Africa -- Eastern Cape , Entrepreneurship -- South Africa -- Eastern Cape , Sex discrimination -- South Africa -- Eastern Cape
- Description: This study examined the influence of gender on access to venture capital and firm performance on Small, Medium and Micro Enterprises in King Williams Town, South Africa. This study sought to establish whether there was differential access to venture capital between genders; to establish whether men- and women-owned SMMEs differ in performance; to identify whether an association between gender and business related experience can be found; and to assess the extent to which the gender gap in SMME access to venture capital and performance could be allocated to gender differences in levels of business related experience. A total sample of 109 SMMEs was used which comprised 53 female- and 56 male-owned. The quota sampling technique was implemented and a self-administered questionnaire was used for the purpose of gathering primary data. Data for this study was gathered from SMME owners only as they were the targeted respondents. The t-test and Chi-square test were used for the statistical analysis in order to arrive at findings and conclusions. Based on a 64% survey response rate, the study reports the existence of statistically significant gender gap in SMME access to venture capital and SMME performance. In addition, this study also reports the existence of a gender gap in business related experience amongst SMME owners. However, after controlling for business related experience, the gender gap in SMMEs access to venture capital and performance disappears. This study therefore argues that the variation in business related experience between gender plays a major role in the noted gender gap. This study therefore concludes that addressing gender gap in business related experience is of vital importance as this would also assist in eliminating the apparent gender gap in access to venture capital and firm performance. To address the gender gap in business related experience, the study recommends that innovations in the design and delivery of training programmes should be implemented. Establishing and monitoring targets for current women managers who are also potential future business owners/SMME owners, should be a policy being practiced in both the private and public sector, among other recommendations outlined in the study.
- Full Text:
- Date Issued: 2014
- Authors: Shava, Herring
- Date: 2014
- Subjects: Small business -- South Africa -- Eastern Cape , Venture capital -- South Africa -- Eastern Cape , Entrepreneurship -- South Africa -- Eastern Cape , Sex discrimination -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , M Com (Business Management)
- Identifier: http://hdl.handle.net/10353/767 , vital:26495 , Small business -- South Africa -- Eastern Cape , Venture capital -- South Africa -- Eastern Cape , Entrepreneurship -- South Africa -- Eastern Cape , Sex discrimination -- South Africa -- Eastern Cape
- Description: This study examined the influence of gender on access to venture capital and firm performance on Small, Medium and Micro Enterprises in King Williams Town, South Africa. This study sought to establish whether there was differential access to venture capital between genders; to establish whether men- and women-owned SMMEs differ in performance; to identify whether an association between gender and business related experience can be found; and to assess the extent to which the gender gap in SMME access to venture capital and performance could be allocated to gender differences in levels of business related experience. A total sample of 109 SMMEs was used which comprised 53 female- and 56 male-owned. The quota sampling technique was implemented and a self-administered questionnaire was used for the purpose of gathering primary data. Data for this study was gathered from SMME owners only as they were the targeted respondents. The t-test and Chi-square test were used for the statistical analysis in order to arrive at findings and conclusions. Based on a 64% survey response rate, the study reports the existence of statistically significant gender gap in SMME access to venture capital and SMME performance. In addition, this study also reports the existence of a gender gap in business related experience amongst SMME owners. However, after controlling for business related experience, the gender gap in SMMEs access to venture capital and performance disappears. This study therefore argues that the variation in business related experience between gender plays a major role in the noted gender gap. This study therefore concludes that addressing gender gap in business related experience is of vital importance as this would also assist in eliminating the apparent gender gap in access to venture capital and firm performance. To address the gender gap in business related experience, the study recommends that innovations in the design and delivery of training programmes should be implemented. Establishing and monitoring targets for current women managers who are also potential future business owners/SMME owners, should be a policy being practiced in both the private and public sector, among other recommendations outlined in the study.
- Full Text:
- Date Issued: 2014
The influence of gold nanoparticles on the electroactivity of nickel tetrasulfonated phthalocyanine
- Maringa, Audacity, Nyokong, Tebello
- Authors: Maringa, Audacity , Nyokong, Tebello
- Date: 2014
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/189774 , vital:44930 , xlink:href="https://doi.org/10.1142/S1088424614500333"
- Description: We report on the electrodeposition of gold nanoparticles (AuNPs) on a glassy carbon electrode (GCE) followed by deposition of nickel tetrasulfonated phthalocyanine (NiTSPc) film by electropolymerization (poly-NiTSPc-GCE) to form Poly-NiTSPc/AuNPs-GCE. The presence of the gold nanoparticles caused a lowering of the anodic and cathodic peak separation (ΔEp) of ferricyanide from 126 mV on poly-NiTSPc to 110 mV on poly-NiTSPc/AuNPs. The electrooxidation of nitrite improved on modified electrodes compared to GCE, with the latter giving Ep = 0.78 V and the modified electrodes gave Ep = 0.62 V or 0.61 V. Poly-NiTSPc/AuNPs-GCE had higher currents compared to poly-NiTSPc-GCE. This indicates the enhancement effect caused by the AuNPs. Electrochemical impedance spectroscopy and chronoamperometric studies also showed that poly-NiTSPc/AuNPs-GCE was a better electrocatalyst than poly-NiTSPc-GCE or AuNPs-GCE.
- Full Text:
- Date Issued: 2014
- Authors: Maringa, Audacity , Nyokong, Tebello
- Date: 2014
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/189774 , vital:44930 , xlink:href="https://doi.org/10.1142/S1088424614500333"
- Description: We report on the electrodeposition of gold nanoparticles (AuNPs) on a glassy carbon electrode (GCE) followed by deposition of nickel tetrasulfonated phthalocyanine (NiTSPc) film by electropolymerization (poly-NiTSPc-GCE) to form Poly-NiTSPc/AuNPs-GCE. The presence of the gold nanoparticles caused a lowering of the anodic and cathodic peak separation (ΔEp) of ferricyanide from 126 mV on poly-NiTSPc to 110 mV on poly-NiTSPc/AuNPs. The electrooxidation of nitrite improved on modified electrodes compared to GCE, with the latter giving Ep = 0.78 V and the modified electrodes gave Ep = 0.62 V or 0.61 V. Poly-NiTSPc/AuNPs-GCE had higher currents compared to poly-NiTSPc-GCE. This indicates the enhancement effect caused by the AuNPs. Electrochemical impedance spectroscopy and chronoamperometric studies also showed that poly-NiTSPc/AuNPs-GCE was a better electrocatalyst than poly-NiTSPc-GCE or AuNPs-GCE.
- Full Text:
- Date Issued: 2014
The influence of indigenous languages on Ugandan English as used in the media
- Authors: Tukwasibwe, Constance
- Date: 2014
- Subjects: Mass media and language -- Uganda , Languages in contact -- Uganda , English language -- Uganda , Language transfer (Language learning) -- Uganda , Communication and culture -- Uganda , Bilingualism -- Uganda , Linguistic demography -- Uganda , Uganda -- Languages
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:3646 , http://hdl.handle.net/10962/d1015637
- Description: When two or more languages come in contact, they influence each other in various ways, for example through word borrowing, transfer of sounds, morphology and syntax taken from one language system and imported to another. In this study, the primary concern is on the indigenous communities of Uganda learning the English language, plus the influence that this interaction brings into the linguistic space. Bringing the Ugandan multilingual situation into perspective, the study looks at how the English language has interacted with the local languages and the local speech habits, customs and traditions of the indigenous people, to the extent that it has been indigenized. Some word usage results in miscommunication due to the socio-cultural uniqueness of Ugandan cultural expressions. As an example, because of the practice of polygamy in most Ugandan cultures, words like co-wife are coined to mean 'a woman who shares a husband, or a husband's other wife', a word that is absent in both the language and culture of native English speakers. Furthermore some words are formed by calquing some indigenous language expressions, e.g. 'to eat money' or 'to eat cash', an expression that is calqued from the Luganda phrase, kulya sente. Such word coinages are meant to fill the 'shortfall' where the English language fails to provide adequate equivalents. Understanding the context of this kind of English usage and the influence from the indigenous languages is helpful in handling inter-cultural discourses, as the same expression may convey different senses to different people in different contexts. So then, this study deals with some peculiarities of Ugandan English, namely; the features of Ugandan English grammar which are influenced by the indigenous languages. Evidence from the Corpus of Ugandan English is explored to establish that indigenous languages in Uganda have a significant influence on the English language variety spoken in the country, and that a large part of English bilingual speakers cannot speak English without transferring the features from their mother tongue or indeed, switching and mixing codes. A British corpus was used for the purposes of comparison with Ugandan English. The research was conducted in Uganda, drawing data from English newspapers, radio and television talk -shows that were recorded to provide a structural analysis of the contact situations. The result of the study points to the fact that, indeed, the phonological, morpho-syntactic and semantic characteristics of Ugandan English have a considerable amount of influence from indigenous local languages. This study is hinged on the assumption that when indigenous languages and the target language come together in a linguistic contact situation, the resulting variety would exhibit distinct phonological, lexical, grammatical and semantic/pragmatic features ( cf. Sankoff, 2001; Thomason, 1995; Thomason & Kaufman, 1988; Winford, 2005). However, some of these innovations have attracted criticism from 'prescriptivists' such as Quirk (1985, 1988, 1990); Gaudio (2011); and Abbot (1991) who perceive them as 'nonstandard', 'incorrect English language usage' and a 'direct translation from the language user's mother tongue into English'. Yet, indigenous languages continue to play important roles in shaping the kind of English language usage in Uganda.
- Full Text:
- Date Issued: 2014
- Authors: Tukwasibwe, Constance
- Date: 2014
- Subjects: Mass media and language -- Uganda , Languages in contact -- Uganda , English language -- Uganda , Language transfer (Language learning) -- Uganda , Communication and culture -- Uganda , Bilingualism -- Uganda , Linguistic demography -- Uganda , Uganda -- Languages
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:3646 , http://hdl.handle.net/10962/d1015637
- Description: When two or more languages come in contact, they influence each other in various ways, for example through word borrowing, transfer of sounds, morphology and syntax taken from one language system and imported to another. In this study, the primary concern is on the indigenous communities of Uganda learning the English language, plus the influence that this interaction brings into the linguistic space. Bringing the Ugandan multilingual situation into perspective, the study looks at how the English language has interacted with the local languages and the local speech habits, customs and traditions of the indigenous people, to the extent that it has been indigenized. Some word usage results in miscommunication due to the socio-cultural uniqueness of Ugandan cultural expressions. As an example, because of the practice of polygamy in most Ugandan cultures, words like co-wife are coined to mean 'a woman who shares a husband, or a husband's other wife', a word that is absent in both the language and culture of native English speakers. Furthermore some words are formed by calquing some indigenous language expressions, e.g. 'to eat money' or 'to eat cash', an expression that is calqued from the Luganda phrase, kulya sente. Such word coinages are meant to fill the 'shortfall' where the English language fails to provide adequate equivalents. Understanding the context of this kind of English usage and the influence from the indigenous languages is helpful in handling inter-cultural discourses, as the same expression may convey different senses to different people in different contexts. So then, this study deals with some peculiarities of Ugandan English, namely; the features of Ugandan English grammar which are influenced by the indigenous languages. Evidence from the Corpus of Ugandan English is explored to establish that indigenous languages in Uganda have a significant influence on the English language variety spoken in the country, and that a large part of English bilingual speakers cannot speak English without transferring the features from their mother tongue or indeed, switching and mixing codes. A British corpus was used for the purposes of comparison with Ugandan English. The research was conducted in Uganda, drawing data from English newspapers, radio and television talk -shows that were recorded to provide a structural analysis of the contact situations. The result of the study points to the fact that, indeed, the phonological, morpho-syntactic and semantic characteristics of Ugandan English have a considerable amount of influence from indigenous local languages. This study is hinged on the assumption that when indigenous languages and the target language come together in a linguistic contact situation, the resulting variety would exhibit distinct phonological, lexical, grammatical and semantic/pragmatic features ( cf. Sankoff, 2001; Thomason, 1995; Thomason & Kaufman, 1988; Winford, 2005). However, some of these innovations have attracted criticism from 'prescriptivists' such as Quirk (1985, 1988, 1990); Gaudio (2011); and Abbot (1991) who perceive them as 'nonstandard', 'incorrect English language usage' and a 'direct translation from the language user's mother tongue into English'. Yet, indigenous languages continue to play important roles in shaping the kind of English language usage in Uganda.
- Full Text:
- Date Issued: 2014
The influence of organisational climate on job performance
- Authors: Meintjies, Jean
- Date: 2014
- Subjects: Organizational behaviour Organizational effectiveness Employees -- Attitudes
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/10286 , vital:26649
- Description: Organisational climate, as represented by the aggregation of the perceptions of the individual employees within the organisation, has been the focus of considerable empirical research that can be traced back to the work of Lewin, Lippit and White (1939).The debate around organisational climate research, concentrates on the methodological issue of how the construct of such climate can be translated into an indicator of organisational effectiveness. Schneider and Bowen (1985), Bacayan and White (1993) have provided evidence that a worthy and functional organisational climate does have a positive effect upon service outcomes and hence improves organisational success. The study examines the influence of organisational participants’ perception of work environment on job performance in a sample of employees within the various departments of Transnet National Ports Authority. The paper presents that the perception of organisational climate has a significant effect on job performance of some employees while it is not so for others. The research sample consists of 71 employees working in the marine and operations, engineering, human resource, marketing and legal departments. One questionnaire was designed by the researcher to measure organisational climate and the effectiveness of job performance. The climate dimensions of communication, management and supervision, reward and recognition and training are significantly related to job performance. The research consisted of the organisational climate and job performance literature and the subsequent link between these two constructs within Transnet National Ports Authority. In conclusion the report presents the authors findings, conclusions and recommendations derived from the study.
- Full Text:
- Date Issued: 2014
- Authors: Meintjies, Jean
- Date: 2014
- Subjects: Organizational behaviour Organizational effectiveness Employees -- Attitudes
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/10286 , vital:26649
- Description: Organisational climate, as represented by the aggregation of the perceptions of the individual employees within the organisation, has been the focus of considerable empirical research that can be traced back to the work of Lewin, Lippit and White (1939).The debate around organisational climate research, concentrates on the methodological issue of how the construct of such climate can be translated into an indicator of organisational effectiveness. Schneider and Bowen (1985), Bacayan and White (1993) have provided evidence that a worthy and functional organisational climate does have a positive effect upon service outcomes and hence improves organisational success. The study examines the influence of organisational participants’ perception of work environment on job performance in a sample of employees within the various departments of Transnet National Ports Authority. The paper presents that the perception of organisational climate has a significant effect on job performance of some employees while it is not so for others. The research sample consists of 71 employees working in the marine and operations, engineering, human resource, marketing and legal departments. One questionnaire was designed by the researcher to measure organisational climate and the effectiveness of job performance. The climate dimensions of communication, management and supervision, reward and recognition and training are significantly related to job performance. The research consisted of the organisational climate and job performance literature and the subsequent link between these two constructs within Transnet National Ports Authority. In conclusion the report presents the authors findings, conclusions and recommendations derived from the study.
- Full Text:
- Date Issued: 2014
The influence of performance management systems on employee engagement
- Brewis, Willem Christiaan Coenraad
- Authors: Brewis, Willem Christiaan Coenraad
- Date: 2014
- Subjects: Performance standards , Sales personne -- Rating of
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8836 , http://hdl.handle.net/10948/d1019957
- Description: This study focused on investigating different performance management systems and the possibility to introduce a performance management system (PMS) into the sales environment of a company. The company the researcher is working for does not have an official PMS and feel the need to investigate the possibility to introduce a PMS. The study investigated an appropriate PMS that promotes engagement levels with employees that will be the ideal system for the sales environment in the company. Both the PMS and engagement impact on employees were addressed and the suitable PMS was selected. Implementing a system within a selected division the researcher will compile a road map for implementing a PMS into the rest of the company with the background and learning done while implementing the system. The employees participated willingly in a survey. The questionnaire assessed the employees understanding of what a PMS is. Further, the questionnaire assessed if the company does have a PMS system in place. The engagement levels of employees were measured and this allowed management to make the appropriate changes to get the employees engaged in the workplace. The results from the survey show that the employees understand and have a need for a PMS. They do understand how a PMS in the workplace work. The company has a system in place to compensate employees for work done. The company does not deal with underperformance and engagement levels are very low. The factors of engagement tested were very low and it addressing the engagement factors integrated in a PMS will increase engagement levels with employees.
- Full Text:
- Date Issued: 2014
- Authors: Brewis, Willem Christiaan Coenraad
- Date: 2014
- Subjects: Performance standards , Sales personne -- Rating of
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: vital:8836 , http://hdl.handle.net/10948/d1019957
- Description: This study focused on investigating different performance management systems and the possibility to introduce a performance management system (PMS) into the sales environment of a company. The company the researcher is working for does not have an official PMS and feel the need to investigate the possibility to introduce a PMS. The study investigated an appropriate PMS that promotes engagement levels with employees that will be the ideal system for the sales environment in the company. Both the PMS and engagement impact on employees were addressed and the suitable PMS was selected. Implementing a system within a selected division the researcher will compile a road map for implementing a PMS into the rest of the company with the background and learning done while implementing the system. The employees participated willingly in a survey. The questionnaire assessed the employees understanding of what a PMS is. Further, the questionnaire assessed if the company does have a PMS system in place. The engagement levels of employees were measured and this allowed management to make the appropriate changes to get the employees engaged in the workplace. The results from the survey show that the employees understand and have a need for a PMS. They do understand how a PMS in the workplace work. The company has a system in place to compensate employees for work done. The company does not deal with underperformance and engagement levels are very low. The factors of engagement tested were very low and it addressing the engagement factors integrated in a PMS will increase engagement levels with employees.
- Full Text:
- Date Issued: 2014
The Influence of School Environmental Factors on Grade 12 Learners’ Academic Performances
- Authors: SIKUZA PUMLA MARJORIE
- Date: 2014
- Language: English
- Type: Masters
- Identifier: http://hdl.handle.net/11260/2822 , vital:42959
- Full Text:
- Authors: SIKUZA PUMLA MARJORIE
- Date: 2014
- Language: English
- Type: Masters
- Identifier: http://hdl.handle.net/11260/2822 , vital:42959
- Full Text:
The influence of selected variables on motor vehicle-related purchasing behaviour
- Authors: Nkoyi, Anele
- Date: 2014
- Subjects: Motor vehicles -- Purchasing , Consumer behavior , Marketing -- Decision making
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: http://hdl.handle.net/10948/9119 , vital:26466
- Description: Marketers are faced with informed and highly complex consumers. The consumer market is becoming more competitive and more difficult to predict as consumers make purchase decisions in their everyday life. An ongoing need exists for information and an examination of purchasing behaviour for marketers to succeed in their pursuit of business endeavours. This study examines the influence of selected variables on motor vehicle-related purchasing behaviour. Five independent variables, namely branding, price, promotion, safety features and colour were investigated and the dependent variable (purchasing behaviour) was examined. In doing so, various stages which consumers undergo when making purchasing decisions were discussed. These stages were outlined as need recognition, information search, and evaluation of alternatives, purchase and post-purchase behaviour. The primary research objective of this study was to determine the influence of selected variables on motor vehicle-related purchasing behaviour. In order to achieve the objectives of the study, an empirical investigation was undertaken. The quantitative (positivistic) paradigm was used in this study, as the aim was to test the hypotheses and conceptualmodel of the study using statistical analysis. In gathering primary data, 192 self-administered questionnaires were issued to respondents for completion by means of convenience and quota non-probability sampling. Upon completion of all the questionnaires, data was analysed in order to arrive at the conclusions regarding the research questions. The empirical findings and analysis followed a systematic and statistical process, where exploratory factor analysis using target rotation was used to test the validity of the measuring instrument. Cronbach alpha correlation coefficients were used to confirm the reliability of the measuring instrument, while multiple regression analysis was carried out to test the hypothesised relationships between the independent variables and the dependent variable of the study. ANOVA was applied to determine differences in the demographic characteristics of respondents. The main findings on the validity and reliability of the measuring instrument proved to be statistically satisfactory. The main findings which emerged from the multiple regression analysis suggested that price and colour had statistically significant influence on motor vehicle-related purchasing behaviour. Findings revealed that branding, promotion and safety conditions had no significant effects on motor vehicle related purchasing behaviour. Accordingly, the hypotheses for price and colour were accepted and those for branding, promotion and safety conditions were rejected. Therefore according to respondents, price and colour of a motor vehicle are the most important considerations when undertaking purchasing decisions regarding motor vehicles. Additionally, the empirical investigation revealed that significant differences exist between age groups of respondents, meaning that different age groups of respondents had different perceptions and opinions with regard to their purchasing patterns relating to price. Furthermore, significant differences were also found between male and female respondents in terms of price and colour, meaning that the two genders had different perceptions and opinions with regard to their purchasing patterns in these areas. The empirical findings of this study are relevant for motor vehicle retailers and original equipment manufacturers, as the findings provide important information regarding the influence of selected variables on motor vehicle-related purchasing behaviour. Secondly the findings of this study contribute to the body of knowledge regarding purchasing behaviour.
- Full Text: false
- Date Issued: 2014
- Authors: Nkoyi, Anele
- Date: 2014
- Subjects: Motor vehicles -- Purchasing , Consumer behavior , Marketing -- Decision making
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: http://hdl.handle.net/10948/9119 , vital:26466
- Description: Marketers are faced with informed and highly complex consumers. The consumer market is becoming more competitive and more difficult to predict as consumers make purchase decisions in their everyday life. An ongoing need exists for information and an examination of purchasing behaviour for marketers to succeed in their pursuit of business endeavours. This study examines the influence of selected variables on motor vehicle-related purchasing behaviour. Five independent variables, namely branding, price, promotion, safety features and colour were investigated and the dependent variable (purchasing behaviour) was examined. In doing so, various stages which consumers undergo when making purchasing decisions were discussed. These stages were outlined as need recognition, information search, and evaluation of alternatives, purchase and post-purchase behaviour. The primary research objective of this study was to determine the influence of selected variables on motor vehicle-related purchasing behaviour. In order to achieve the objectives of the study, an empirical investigation was undertaken. The quantitative (positivistic) paradigm was used in this study, as the aim was to test the hypotheses and conceptualmodel of the study using statistical analysis. In gathering primary data, 192 self-administered questionnaires were issued to respondents for completion by means of convenience and quota non-probability sampling. Upon completion of all the questionnaires, data was analysed in order to arrive at the conclusions regarding the research questions. The empirical findings and analysis followed a systematic and statistical process, where exploratory factor analysis using target rotation was used to test the validity of the measuring instrument. Cronbach alpha correlation coefficients were used to confirm the reliability of the measuring instrument, while multiple regression analysis was carried out to test the hypothesised relationships between the independent variables and the dependent variable of the study. ANOVA was applied to determine differences in the demographic characteristics of respondents. The main findings on the validity and reliability of the measuring instrument proved to be statistically satisfactory. The main findings which emerged from the multiple regression analysis suggested that price and colour had statistically significant influence on motor vehicle-related purchasing behaviour. Findings revealed that branding, promotion and safety conditions had no significant effects on motor vehicle related purchasing behaviour. Accordingly, the hypotheses for price and colour were accepted and those for branding, promotion and safety conditions were rejected. Therefore according to respondents, price and colour of a motor vehicle are the most important considerations when undertaking purchasing decisions regarding motor vehicles. Additionally, the empirical investigation revealed that significant differences exist between age groups of respondents, meaning that different age groups of respondents had different perceptions and opinions with regard to their purchasing patterns relating to price. Furthermore, significant differences were also found between male and female respondents in terms of price and colour, meaning that the two genders had different perceptions and opinions with regard to their purchasing patterns in these areas. The empirical findings of this study are relevant for motor vehicle retailers and original equipment manufacturers, as the findings provide important information regarding the influence of selected variables on motor vehicle-related purchasing behaviour. Secondly the findings of this study contribute to the body of knowledge regarding purchasing behaviour.
- Full Text: false
- Date Issued: 2014
The influence of the extended family on the social and moral development of the child in the single parent family
- Terblanche, Malise Georgette
- Authors: Terblanche, Malise Georgette
- Date: 2014
- Subjects: Moral education , Children of single parents , Single-parent families , Extended families
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:9586 , http://hdl.handle.net/10948/d1020987
- Description: The single-parent family can no longer be viewed as a non-traditional family type. As more single-parent families become prevalent in our society, interest in this family type has increased. Research associated with single-parent families often focus on the pathology associated with single-parent families. It is apparent that single-parent households, whether headed by a mother or father often have more to deal with than the traditional two-parent family. However, as a single-parent herself, the researcher also knows that this family type has much to offer. This research is undertaken in an exploratory and interpretive manner to illuminate the influence which the extended family have on the social and moral development of the child in the single-parent family. The researcher, just like Monama (2007:iv) before her, wishes to elevate the view of single-parents from the stereotypical victims to responsible archetypes. As this research is undertaken with the eco-systemic perspective of Bronfenbrenner as theoretical orientation, it therefore focuses on the systems in which the child is nested and more specifically the extended family as part of the child’s microsystem. This research aims to be beneficial to single-parents, families, members of community organizations, educators and other allied professionals.
- Full Text:
- Date Issued: 2014
- Authors: Terblanche, Malise Georgette
- Date: 2014
- Subjects: Moral education , Children of single parents , Single-parent families , Extended families
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:9586 , http://hdl.handle.net/10948/d1020987
- Description: The single-parent family can no longer be viewed as a non-traditional family type. As more single-parent families become prevalent in our society, interest in this family type has increased. Research associated with single-parent families often focus on the pathology associated with single-parent families. It is apparent that single-parent households, whether headed by a mother or father often have more to deal with than the traditional two-parent family. However, as a single-parent herself, the researcher also knows that this family type has much to offer. This research is undertaken in an exploratory and interpretive manner to illuminate the influence which the extended family have on the social and moral development of the child in the single-parent family. The researcher, just like Monama (2007:iv) before her, wishes to elevate the view of single-parents from the stereotypical victims to responsible archetypes. As this research is undertaken with the eco-systemic perspective of Bronfenbrenner as theoretical orientation, it therefore focuses on the systems in which the child is nested and more specifically the extended family as part of the child’s microsystem. This research aims to be beneficial to single-parents, families, members of community organizations, educators and other allied professionals.
- Full Text:
- Date Issued: 2014
The influence of the human-companionate dog bond on psychological well-being
- Authors: Holm, Robyn Janet
- Date: 2014
- Subjects: Well-being , Fellowship , Human-animal relationships
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9971 , http://hdl.handle.net/10948/d1020978
- Description: Many individuals across the world own dogs for a variety of reasons. For some individuals, dogs can be viewed as providing the most important relationship in their lives. Others may own dogs for protection, companionship, and even health benefits. Some families across the world view their dogs as family members and a vital aspect of the family unit. This study explored the perceived bond between a human and a dog and how this bond influenced the human‟s psychological well-being. Although studies have been conducted on the human-companionate dog bond, empirical research on the perceptions of the bond between a dog and a human and the influence it has on an individual‟s psychological well-being, falls short. Studies on the human-companionate bond have been on the rise internationally, yet studies in this field in the South African context are scarce. This study contributes to psychology‟s broad body of knowledge regarding the human-companionate dog bond and identifies the important influences the bond has on human psychological well-being. The researcher utilized a qualitative research approach. A non-probability purposive sample was employed and semi-structured interviews were conducted with seven participants. Two participants were male and five were female. All participants had developed a bond with their dog and were able to speak English fluently. Interviews were conducted until data saturation was reached. Results demonstrate that having a human-companionate dog bond can enhance an individual's psychological well-being. Themes identified demonstrate that a human-companionate dog bond can enhance physical health, relational well-being, and mental health. This bond also fulfils specific individual needs which enhance psychological well-being. Limitations of the study and recommendations for further research are identified.
- Full Text:
- Date Issued: 2014
- Authors: Holm, Robyn Janet
- Date: 2014
- Subjects: Well-being , Fellowship , Human-animal relationships
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9971 , http://hdl.handle.net/10948/d1020978
- Description: Many individuals across the world own dogs for a variety of reasons. For some individuals, dogs can be viewed as providing the most important relationship in their lives. Others may own dogs for protection, companionship, and even health benefits. Some families across the world view their dogs as family members and a vital aspect of the family unit. This study explored the perceived bond between a human and a dog and how this bond influenced the human‟s psychological well-being. Although studies have been conducted on the human-companionate dog bond, empirical research on the perceptions of the bond between a dog and a human and the influence it has on an individual‟s psychological well-being, falls short. Studies on the human-companionate bond have been on the rise internationally, yet studies in this field in the South African context are scarce. This study contributes to psychology‟s broad body of knowledge regarding the human-companionate dog bond and identifies the important influences the bond has on human psychological well-being. The researcher utilized a qualitative research approach. A non-probability purposive sample was employed and semi-structured interviews were conducted with seven participants. Two participants were male and five were female. All participants had developed a bond with their dog and were able to speak English fluently. Interviews were conducted until data saturation was reached. Results demonstrate that having a human-companionate dog bond can enhance an individual's psychological well-being. Themes identified demonstrate that a human-companionate dog bond can enhance physical health, relational well-being, and mental health. This bond also fulfils specific individual needs which enhance psychological well-being. Limitations of the study and recommendations for further research are identified.
- Full Text:
- Date Issued: 2014
The influence of the therapist's activities on clients' subject positioning in relation to gender in narrative couples therapy
- Authors: Friis, Kirsten Leigh
- Date: 2014
- Subjects: Narrative therapy , Couples therapy , Therapist and patient , Control (Psychology) , Critical discourse analysis , Psychotherapy -- Methods
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3227 , http://hdl.handle.net/10962/d1013050
- Description: Narrative Therapy draws on an understanding of how discourse acts to construct, reproduce and deconstruct power relationships. Therapy is focussed on collaborating with clients in a process of re-authoring their self-stories by critically evaluating the positions made available to them in relation to dominant discourses. Whilst there is a large body of theoretical knowledge on post-structuralism and psychotherapy, very few discourse analyses of psychotherapy sessions have been published. Thus, though post-structuralist therapeutic approaches are theoretically well supported, there is an identified gap in the literature on the therapeutic processes that occur within practice. This research aims to further explore these therapeutic processes, focussing specifically on subject positioning with relation to gender in Narrative Couple Therapy, and the influence of the therapist thereupon. It is based on the analysis of a video of a Michael White Narrative Couple Therapy session, "The Best of Friends." Using discourse analysis as a methodological approach, the analysis seeks first to identify talk that signifies discourses of gender difference, and then to explore how the subjects (therapist and clients) are positioned in relation to these discourses. The analysis focuses on the therapist's activities to investigate the influence of his interactions with the partners on how they are positioned or position themselves within stories of gender difference. The analysis shows that, by working reflexively, transparently and collaboratively with the partners, the therapist assists to render power, restrictive discourses, and alternate positions visible to the clients. The therapist resists being drawn into dominant therapy discourses of expert and patient, and instead continuously recognises the knowledges and expertise that the clients bring to the therapy context. He then works closely with the clients to thicken alternative representations of self.
- Full Text:
- Date Issued: 2014
- Authors: Friis, Kirsten Leigh
- Date: 2014
- Subjects: Narrative therapy , Couples therapy , Therapist and patient , Control (Psychology) , Critical discourse analysis , Psychotherapy -- Methods
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3227 , http://hdl.handle.net/10962/d1013050
- Description: Narrative Therapy draws on an understanding of how discourse acts to construct, reproduce and deconstruct power relationships. Therapy is focussed on collaborating with clients in a process of re-authoring their self-stories by critically evaluating the positions made available to them in relation to dominant discourses. Whilst there is a large body of theoretical knowledge on post-structuralism and psychotherapy, very few discourse analyses of psychotherapy sessions have been published. Thus, though post-structuralist therapeutic approaches are theoretically well supported, there is an identified gap in the literature on the therapeutic processes that occur within practice. This research aims to further explore these therapeutic processes, focussing specifically on subject positioning with relation to gender in Narrative Couple Therapy, and the influence of the therapist thereupon. It is based on the analysis of a video of a Michael White Narrative Couple Therapy session, "The Best of Friends." Using discourse analysis as a methodological approach, the analysis seeks first to identify talk that signifies discourses of gender difference, and then to explore how the subjects (therapist and clients) are positioned in relation to these discourses. The analysis focuses on the therapist's activities to investigate the influence of his interactions with the partners on how they are positioned or position themselves within stories of gender difference. The analysis shows that, by working reflexively, transparently and collaboratively with the partners, the therapist assists to render power, restrictive discourses, and alternate positions visible to the clients. The therapist resists being drawn into dominant therapy discourses of expert and patient, and instead continuously recognises the knowledges and expertise that the clients bring to the therapy context. He then works closely with the clients to thicken alternative representations of self.
- Full Text:
- Date Issued: 2014
The influence of viewing context on meaning making : a reception study of the popular drama series Intersexions in Ginsberg township
- Authors: Ponono, Mvuzo
- Date: 2014
- Subjects: Intersexions (Television program) , Meaning (Psychology) , Context effects (Psychology) , Television programs -- South Africa , Television -- Social aspects -- South Africa , Television viewers -- South Africa -- Eastern Cape , Television viewers -- South Africa -- Eastern Cape -- Attitudes , Educational television programs -- South Africa , AIDS (Disease) in mass media -- South Africa , South Africa -- Social life and customs
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3528 , http://hdl.handle.net/10962/d1013093
- Description: This study examines the home as a context of viewing for the television programme Intersexions in the township of Ginsberg in the Eastern Cape. The central question asked is whether the household influences the interpretation of the programme. The research was mainly conducted through ethnographical methods of participant observation and focus group interviews. Six families were observed and six gender-based focus groups convened. Drawing from the work of Morley (1986) and Lull (1990) that argues that the home be taken more seriously as a context of viewing; this study posits that the home is a rule-bound micro-society that influences the interpretation of media messages. As a starting point, this study contends with the arguments that the South African government has been slow to acknowledge the extent of the problem presented by the HIV/AIDS pandemic. Much has been written about the inefficiency of state efforts to educate the public, with some pundits suggesting that government communications strategies have largely been outdated and thus resisted by audiences (Treffry-Goatley, Mahlinza & Imrie, 2013). To counter the pandemic, a large number of independent educational television serials have been launched in South Africa, and met with popular appeal since 1994. Furthermore, this development is in line with global trends of high audience ratings for Entertainment- Education (EE) programmes (Singhal et al., 1993). To investigate complex issue of EE reception by audiences in this burgeoning area of study, the programme at the centre of this study, Intersexions, is a good example. The serial, which concluded its second season in August 2013, is second to only the established soap opera, Generations, in television ratings in South Africa. Therefore, the impressive ratings garnered by educational serials in South Africa are a chance for audience studies to study audiences in context. This research investigates Intersexions using the understanding that television audiences must be analysed in "cultural and historic specific" sites because the struggle to make meanings of texts takes place at the moment when the text and subject meet (Fiske, 1987). This research investigates the assumption that the meanings made by audiences depend not just on the text, but also on environment. This means that the research delves into the situational context in which media are used and interpreted. Therefore, the central aim of this study is to analyse television viewing of the entertainment education programme, Intersexions, in the natural setting of the home, which is in line with analysing television viewers in cultural and historically specific sites.
- Full Text:
- Date Issued: 2014
- Authors: Ponono, Mvuzo
- Date: 2014
- Subjects: Intersexions (Television program) , Meaning (Psychology) , Context effects (Psychology) , Television programs -- South Africa , Television -- Social aspects -- South Africa , Television viewers -- South Africa -- Eastern Cape , Television viewers -- South Africa -- Eastern Cape -- Attitudes , Educational television programs -- South Africa , AIDS (Disease) in mass media -- South Africa , South Africa -- Social life and customs
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:3528 , http://hdl.handle.net/10962/d1013093
- Description: This study examines the home as a context of viewing for the television programme Intersexions in the township of Ginsberg in the Eastern Cape. The central question asked is whether the household influences the interpretation of the programme. The research was mainly conducted through ethnographical methods of participant observation and focus group interviews. Six families were observed and six gender-based focus groups convened. Drawing from the work of Morley (1986) and Lull (1990) that argues that the home be taken more seriously as a context of viewing; this study posits that the home is a rule-bound micro-society that influences the interpretation of media messages. As a starting point, this study contends with the arguments that the South African government has been slow to acknowledge the extent of the problem presented by the HIV/AIDS pandemic. Much has been written about the inefficiency of state efforts to educate the public, with some pundits suggesting that government communications strategies have largely been outdated and thus resisted by audiences (Treffry-Goatley, Mahlinza & Imrie, 2013). To counter the pandemic, a large number of independent educational television serials have been launched in South Africa, and met with popular appeal since 1994. Furthermore, this development is in line with global trends of high audience ratings for Entertainment- Education (EE) programmes (Singhal et al., 1993). To investigate complex issue of EE reception by audiences in this burgeoning area of study, the programme at the centre of this study, Intersexions, is a good example. The serial, which concluded its second season in August 2013, is second to only the established soap opera, Generations, in television ratings in South Africa. Therefore, the impressive ratings garnered by educational serials in South Africa are a chance for audience studies to study audiences in context. This research investigates Intersexions using the understanding that television audiences must be analysed in "cultural and historic specific" sites because the struggle to make meanings of texts takes place at the moment when the text and subject meet (Fiske, 1987). This research investigates the assumption that the meanings made by audiences depend not just on the text, but also on environment. This means that the research delves into the situational context in which media are used and interpreted. Therefore, the central aim of this study is to analyse television viewing of the entertainment education programme, Intersexions, in the natural setting of the home, which is in line with analysing television viewers in cultural and historically specific sites.
- Full Text:
- Date Issued: 2014
The information-seeking behaviour of economically disadvantaged communities: a case study of the Amsterdam community in the Mpumalanga Province of South Africa
- Authors: Chimezie Obi
- Date: 2014
- Subjects: Information behavior , Information resources
- Language: English
- Type: Thesis , Masters , M Bibl
- Identifier: vital:11574 , http://hdl.handle.net/10353/d1015358 , Information behavior , Information resources
- Description: This study examined the information – seeking behaviour of members of the economically disadvantaged community of Amsterdam. The study involved both a qualitative and quantitative investigation of the critical factors that affected information – seeking, need, and use in the Amsterdam community. The research design included a study of various information behaviour models with particular emphasis on Wilson’s 1996 general model of information – seeking behaviour. The three factors identified by Wilson for the study of various groups’ information behaviour were personality, work – related or work – role and environmental factors. Information science researchers, in the study of rural communities’ information behaviour, have used these three factors extensively. The data collection was triangulated with the use of survey, observations, and focus group discussions and in – depth interviews. The findings show how the person, in the context of information – seeking and the role-played within a given environment, could determine information needs and use. A person in the context of information – seeking, could be a father, a mother, a group leader, a nurse or a teacher. The main elements are the situation within which a need for information arises, and the person performing a role in an environment situated within the context of information – seeking. Information was found to be a critical commodity for the socio – economic, political, and educational development of any given community. Recommendations were made that could transform the community of Amsterdam, through the provision of sustainable information.
- Full Text:
- Date Issued: 2014
- Authors: Chimezie Obi
- Date: 2014
- Subjects: Information behavior , Information resources
- Language: English
- Type: Thesis , Masters , M Bibl
- Identifier: vital:11574 , http://hdl.handle.net/10353/d1015358 , Information behavior , Information resources
- Description: This study examined the information – seeking behaviour of members of the economically disadvantaged community of Amsterdam. The study involved both a qualitative and quantitative investigation of the critical factors that affected information – seeking, need, and use in the Amsterdam community. The research design included a study of various information behaviour models with particular emphasis on Wilson’s 1996 general model of information – seeking behaviour. The three factors identified by Wilson for the study of various groups’ information behaviour were personality, work – related or work – role and environmental factors. Information science researchers, in the study of rural communities’ information behaviour, have used these three factors extensively. The data collection was triangulated with the use of survey, observations, and focus group discussions and in – depth interviews. The findings show how the person, in the context of information – seeking and the role-played within a given environment, could determine information needs and use. A person in the context of information – seeking, could be a father, a mother, a group leader, a nurse or a teacher. The main elements are the situation within which a need for information arises, and the person performing a role in an environment situated within the context of information – seeking. Information was found to be a critical commodity for the socio – economic, political, and educational development of any given community. Recommendations were made that could transform the community of Amsterdam, through the provision of sustainable information.
- Full Text:
- Date Issued: 2014
The intellectualisation of African languages, multilingualism and education: a research-based approach
- Kaschula, Russell H, Maseko, Pamela
- Authors: Kaschula, Russell H , Maseko, Pamela
- Date: 2014
- Subjects: African languages -- Study and teaching (Higher) -- South Africa , Language policy -- South Africa , Education, Higher -- South Africa , Educational change -- South Africa , Multiligualism , Multicultural education -- South Africa , Language and languages -- Study and teaching
- Language: English
- Type: article , text
- Identifier: http://hdl.handle.net/10962/59321 , vital:27548 , http://alternation.ukzn.ac.za/Files/docs/21 SpEd13/Alternation Spec Ed 13 (2014).pdf#page=13
- Description: This paper seeks to understand the relationship between the intellectualisation of African languages and the facilitation of a research approach which will enhance this intellectualisation. The paper examines the legislative language policies and other documents published by government since 1994, which guide language use and practices in higher education, including the Catalytic Project on Concept Formation in indigenous African languages (one of the recommendations contained in the Report commissioned by the Minister of Higher Education for the Charter for Humanities and Social Sciences and the language clauses of the Green Paper for Post-Secondary School Education and Training). These policy documents are analysed against the backdrop of the research work of the newly initiated NRF SARChI Chair in the Intellectualisation of African Languages, Multilingualism and Education hosted by Rhodes University. The paper argues that while policy provides an enabling environment for the promotion and development of indigenous African languages and advocates for promotion of equity and equality, in actual fact, HEIs still grapple in implementing provisions of these policies. The paper further discusses the teaching, learning and research in the African Language Studies Section of the School of Languages at Rhodes University and how the Section adopted the provisions of the national policy and institutional policy on language in turning itself into a source of intellectual vitality in the teaching, learning and research of particularly isiXhosa. Six focus areas of research, linked to the NRF SARChI Chair, will be outlined in order to create a practical link between Policy, Implementation and the Intellectualisation of African Languages. , Ucwaningo lolu luhlose ukuqonda ubudlelwano obuphakathi kokusetshenziswa kwezilimi zesintu emazingeni aphakame kanye nokusetshenziswa kwendlela yocwaningo ezokwengeza amathuba okusetshenziswa kwezilimi lezi (Finlayson & Madiba 2002). Ucwaningo luhlaziya inqubomgomo yolimi esemthethweni neminye imibhalo eshicelelwe uhulumeni elawula ukusebenza nokusetshenziswa kwezilimi kwezemfundo ephakame kusuka ngonyaka wezi-1994, kanye ne-Catalytic Project on Concept Formation in indigenous African languages (esinye seziphakamiso esiqukethwe embikweni owethulwa ngungqonqoshe wezemfundo ephakeme nge-Charter of Humanities and Social Sciences (HSSC 2011) kanye nezinhlamvu zamazwi e-Green paper for Post-secondary School education and training (2012). Imibhalo yenqubomgomo ihlaziywa kubhekwe umsebenzi wocwaningo kasihlalo we- NRF SARChl ekusetshenzisweni kwezilimi zesintu emazingeni aphakeme nobuliminingi kanye nezemfundo e- Rhodes University. Ucwaningo lolu luphakamisa umbono othi noma inqubomgomo isipha amandla okukhuphula nokuthuthukisa izilimi zesintu kanye nokukhuthaza ukulingana nokungacwasi, eqinisweni izikhungo zemfundo ephakeme zihlangabezana nobunzima bokusebenzisa izihlinzeko zenqubomgomo. Ucwaningo lolu luzoxoxa futhi ngokufundisa nokufunda kanye nocwaningo emnyangweni wezifundo zezilimi zesintu esikoleni sezilimi e-Rhodes University kanye nokuthi umnyango lo wamukela njani izihlinzeko zenqubomgomo kazwelonke kanye nezesikhungo eziphathelane nokuguqulwa kwezilimi zibe umthombo wenhlakanipho ekufundiseni nasekufundeni kanye nocwaningo ngolimi lwesiXhosa. Imikhaka emqoka eyisithupha yocwaningo ehlobene nesihlalo se-NRF SARChl izovezwa ukuze kwakhiwe ubudlelwano obenzekayo phakathi kwenqubomgomo, ukusetshenziswa kwayo kanye nokusetshenziswa kwezilimi zesintu emazingeni aphakeme.
- Full Text:
- Date Issued: 2014
- Authors: Kaschula, Russell H , Maseko, Pamela
- Date: 2014
- Subjects: African languages -- Study and teaching (Higher) -- South Africa , Language policy -- South Africa , Education, Higher -- South Africa , Educational change -- South Africa , Multiligualism , Multicultural education -- South Africa , Language and languages -- Study and teaching
- Language: English
- Type: article , text
- Identifier: http://hdl.handle.net/10962/59321 , vital:27548 , http://alternation.ukzn.ac.za/Files/docs/21 SpEd13/Alternation Spec Ed 13 (2014).pdf#page=13
- Description: This paper seeks to understand the relationship between the intellectualisation of African languages and the facilitation of a research approach which will enhance this intellectualisation. The paper examines the legislative language policies and other documents published by government since 1994, which guide language use and practices in higher education, including the Catalytic Project on Concept Formation in indigenous African languages (one of the recommendations contained in the Report commissioned by the Minister of Higher Education for the Charter for Humanities and Social Sciences and the language clauses of the Green Paper for Post-Secondary School Education and Training). These policy documents are analysed against the backdrop of the research work of the newly initiated NRF SARChI Chair in the Intellectualisation of African Languages, Multilingualism and Education hosted by Rhodes University. The paper argues that while policy provides an enabling environment for the promotion and development of indigenous African languages and advocates for promotion of equity and equality, in actual fact, HEIs still grapple in implementing provisions of these policies. The paper further discusses the teaching, learning and research in the African Language Studies Section of the School of Languages at Rhodes University and how the Section adopted the provisions of the national policy and institutional policy on language in turning itself into a source of intellectual vitality in the teaching, learning and research of particularly isiXhosa. Six focus areas of research, linked to the NRF SARChI Chair, will be outlined in order to create a practical link between Policy, Implementation and the Intellectualisation of African Languages. , Ucwaningo lolu luhlose ukuqonda ubudlelwano obuphakathi kokusetshenziswa kwezilimi zesintu emazingeni aphakame kanye nokusetshenziswa kwendlela yocwaningo ezokwengeza amathuba okusetshenziswa kwezilimi lezi (Finlayson & Madiba 2002). Ucwaningo luhlaziya inqubomgomo yolimi esemthethweni neminye imibhalo eshicelelwe uhulumeni elawula ukusebenza nokusetshenziswa kwezilimi kwezemfundo ephakame kusuka ngonyaka wezi-1994, kanye ne-Catalytic Project on Concept Formation in indigenous African languages (esinye seziphakamiso esiqukethwe embikweni owethulwa ngungqonqoshe wezemfundo ephakeme nge-Charter of Humanities and Social Sciences (HSSC 2011) kanye nezinhlamvu zamazwi e-Green paper for Post-secondary School education and training (2012). Imibhalo yenqubomgomo ihlaziywa kubhekwe umsebenzi wocwaningo kasihlalo we- NRF SARChl ekusetshenzisweni kwezilimi zesintu emazingeni aphakeme nobuliminingi kanye nezemfundo e- Rhodes University. Ucwaningo lolu luphakamisa umbono othi noma inqubomgomo isipha amandla okukhuphula nokuthuthukisa izilimi zesintu kanye nokukhuthaza ukulingana nokungacwasi, eqinisweni izikhungo zemfundo ephakeme zihlangabezana nobunzima bokusebenzisa izihlinzeko zenqubomgomo. Ucwaningo lolu luzoxoxa futhi ngokufundisa nokufunda kanye nocwaningo emnyangweni wezifundo zezilimi zesintu esikoleni sezilimi e-Rhodes University kanye nokuthi umnyango lo wamukela njani izihlinzeko zenqubomgomo kazwelonke kanye nezesikhungo eziphathelane nokuguqulwa kwezilimi zibe umthombo wenhlakanipho ekufundiseni nasekufundeni kanye nocwaningo ngolimi lwesiXhosa. Imikhaka emqoka eyisithupha yocwaningo ehlobene nesihlalo se-NRF SARChl izovezwa ukuze kwakhiwe ubudlelwano obenzekayo phakathi kwenqubomgomo, ukusetshenziswa kwayo kanye nokusetshenziswa kwezilimi zesintu emazingeni aphakeme.
- Full Text:
- Date Issued: 2014
The interaction between the stock market and macroeconomic variables in South Africa
- Authors: Ntshangase, Khanyisa
- Date: 2014
- Language: English
- Type: Thesis , Masters , M Com
- Identifier: vital:11491 , http://hdl.handle.net/10353/d1018271
- Description: This study investigates the interaction between stock market and macroeconomic variables in South Africa. Apart from the stock market being a channel to raise capital, another important role of the stock market is to provide correct valuation of stocks and promote efficient allocation of capital. This is important given the great need of investment capital in a country such as South Africa. Utilising quarterly data for the period from 1994 to 2012, the study employs the Johansen cointegration test and the Vector Error Correction Model (VECM) to analyse the relationship between these important variables due to the simultaneous nature of the relationship between the variables. Empirical results indicate that all the variables have a significant relationship with the stock market. The findings in this study suggest that it is important to achieve macroeconomic equilibrium in South Africa because any disequilibrium in macroeconomics feeds into the stock market and it is likely to affect investor decision making and hence access to capital by companies listed on the stock exchange.
- Full Text:
- Date Issued: 2014
- Authors: Ntshangase, Khanyisa
- Date: 2014
- Language: English
- Type: Thesis , Masters , M Com
- Identifier: vital:11491 , http://hdl.handle.net/10353/d1018271
- Description: This study investigates the interaction between stock market and macroeconomic variables in South Africa. Apart from the stock market being a channel to raise capital, another important role of the stock market is to provide correct valuation of stocks and promote efficient allocation of capital. This is important given the great need of investment capital in a country such as South Africa. Utilising quarterly data for the period from 1994 to 2012, the study employs the Johansen cointegration test and the Vector Error Correction Model (VECM) to analyse the relationship between these important variables due to the simultaneous nature of the relationship between the variables. Empirical results indicate that all the variables have a significant relationship with the stock market. The findings in this study suggest that it is important to achieve macroeconomic equilibrium in South Africa because any disequilibrium in macroeconomics feeds into the stock market and it is likely to affect investor decision making and hence access to capital by companies listed on the stock exchange.
- Full Text:
- Date Issued: 2014
The interaction of silver nanoparticles with triosephosphate isomerase from human and malarial parasite (Plasmodium falciparum) : a comparative study
- De Moor, Warren Ralph Josephus
- Authors: De Moor, Warren Ralph Josephus
- Date: 2014
- Subjects: Silver , Nanoparticles , Triose-phosphate isomerase , Plasmodium falciparum , Nanotechnology , Antimalarials , Povidone
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4169 , http://hdl.handle.net/10962/d1020895
- Description: The advent of advanced modern nanotechnology techniques offers new and exciting opportunities to develop novel nanotech-derived antimalarial nanodrugs with enhanced selective and targeting abilities that allow for lower effective drug dosages, longer drug persistence and reduced drug degradation within the body. Using a nanodrug approach also has the advantage of avoiding drug resistance problems that plague reconfigured versions of already-existing antimalarial drugs. In this study recombinant triosephosphate isomerase enzymes from Plasmodium falciparum (PfTIM) and Humans (hTIM) were recombinantly expressed, purified and characterised. PfTIM was shown to have optimal pH stability at pH 5.0-5.5 and thermal stability at 25°C with Km 4.34 mM and Vmax 0.876 μmol.ml⁻ₑmin⁻ₑ. For hTIM, these parameters were as follows: pH optima of 6.5-7.0; temperature optima of 30°C, with Km 2.27 mM and Vmax 0.714 μmol.ml⁻ₑmin⁻ₑ. Recombinant TIM enzymes were subjected to inhibition studies using polyvinylpyrrolidone (PVP) stabilised silver nanoparticles (AgNPs) of 4-12 nm in diameter. These studies showed that the AgNPs were able to selectively inhibit PfTIM over hTIM with an 8-fold greater decrease in enzymatic efficiency (Kcat/Km) observed for PfTIM, as compared to hTIM, for kinetics tests done using 0.06 μM of AgNPs. Complete inhibition of PfTIM under optimal conditions was achieved using 0.25 μM AgNPs after 45 minutes while hTIM maintained approximately 31% of its activity at this AgNP concentration. The above results indicate that selective enzymatic targeting of the important, key metabolic enzyme TIM, can be achieved using nanotechnology-derived nanodrugs. It was demonstrated that the key structural differences, between the two enzyme variants, were significant enough to create unique characteristics for each TIM variant, thereby allowing for selective enzyme targeting using AgNPs. If these AgNPs could be coupled with a nanotechnology-derived, targeted localization mechanism – possibly using apoferritin to deliver the AgNPs to infected erythrocytes (Burns and Pollock, 2008) – then such an approach could offer new opportunities for the development of viable antimalarial nanodrugs. For this to be achieved further research into several key areas will be required, including nanoparticle toxicity, drug localization and testing the lethality of the system on live parasite cultures.
- Full Text:
- Date Issued: 2014
- Authors: De Moor, Warren Ralph Josephus
- Date: 2014
- Subjects: Silver , Nanoparticles , Triose-phosphate isomerase , Plasmodium falciparum , Nanotechnology , Antimalarials , Povidone
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4169 , http://hdl.handle.net/10962/d1020895
- Description: The advent of advanced modern nanotechnology techniques offers new and exciting opportunities to develop novel nanotech-derived antimalarial nanodrugs with enhanced selective and targeting abilities that allow for lower effective drug dosages, longer drug persistence and reduced drug degradation within the body. Using a nanodrug approach also has the advantage of avoiding drug resistance problems that plague reconfigured versions of already-existing antimalarial drugs. In this study recombinant triosephosphate isomerase enzymes from Plasmodium falciparum (PfTIM) and Humans (hTIM) were recombinantly expressed, purified and characterised. PfTIM was shown to have optimal pH stability at pH 5.0-5.5 and thermal stability at 25°C with Km 4.34 mM and Vmax 0.876 μmol.ml⁻ₑmin⁻ₑ. For hTIM, these parameters were as follows: pH optima of 6.5-7.0; temperature optima of 30°C, with Km 2.27 mM and Vmax 0.714 μmol.ml⁻ₑmin⁻ₑ. Recombinant TIM enzymes were subjected to inhibition studies using polyvinylpyrrolidone (PVP) stabilised silver nanoparticles (AgNPs) of 4-12 nm in diameter. These studies showed that the AgNPs were able to selectively inhibit PfTIM over hTIM with an 8-fold greater decrease in enzymatic efficiency (Kcat/Km) observed for PfTIM, as compared to hTIM, for kinetics tests done using 0.06 μM of AgNPs. Complete inhibition of PfTIM under optimal conditions was achieved using 0.25 μM AgNPs after 45 minutes while hTIM maintained approximately 31% of its activity at this AgNP concentration. The above results indicate that selective enzymatic targeting of the important, key metabolic enzyme TIM, can be achieved using nanotechnology-derived nanodrugs. It was demonstrated that the key structural differences, between the two enzyme variants, were significant enough to create unique characteristics for each TIM variant, thereby allowing for selective enzyme targeting using AgNPs. If these AgNPs could be coupled with a nanotechnology-derived, targeted localization mechanism – possibly using apoferritin to deliver the AgNPs to infected erythrocytes (Burns and Pollock, 2008) – then such an approach could offer new opportunities for the development of viable antimalarial nanodrugs. For this to be achieved further research into several key areas will be required, including nanoparticle toxicity, drug localization and testing the lethality of the system on live parasite cultures.
- Full Text:
- Date Issued: 2014