An evaluation of the effects of land tenure security in on-farm investment and on-farm productivity: a case of the smallholder farmers in the Amathole District of the Eastern Cape Province of South Africa
- Authors: Zwelendaba, Vincent Vusumzi
- Date: 2014
- Subjects: Land tenure -- South Africa -- Eastern Cape , Agricultural productivity -- South Africa -- Eastern Cape , Farms, Small -- South Africa -- Eastern Cape , Rural development -- South Africa -- Eastern Cape , Community development -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MSc Agric (Agricultural Economics)
- Identifier: vital:11230 , http://hdl.handle.net/10353/d1021282 , Land tenure -- South Africa -- Eastern Cape , Agricultural productivity -- South Africa -- Eastern Cape , Farms, Small -- South Africa -- Eastern Cape , Rural development -- South Africa -- Eastern Cape , Community development -- South Africa -- Eastern Cape
- Description: Smallholder agriculture contributes to poverty alleviation through food price reduction and employment creation. Smallholder farmers have the potential of creating employment because they are labour-intensive. Most small holder farmers in the Amathole District practices dual farming system i.e. crops and livestock production. However these farmers are faced by a number of constraints amongst these are land tenure security, lack of capital, drought, diseases, lack of access to markets and production inputs. The objectives of this study were: to investigate land tenure security impact on-farm investment and on-farm productivity by the smallholder farmers; to assess constraints encountered by the smallholder farmers, to identify factors influencing on-farm investment by the smallholder farmers and to identify factors influencing on-farm productivity by the smallholder farmers. Eighty smallholder farmers were interviewed using a structured questionnaire. The data was analyzed using descriptive statistics (frequency, percentages) and regression analyses. Data was for coded and processed for analysis using Statistical Package for Social Sciences (SPSS). The results revealed that generally, the household demographic characteristics have an influence on the decision to investment in the farm thus on farm productivity. These included age, gender, marital status, educational level and household size of the smallholder farmers. However the findings revealed that smallholder farmers were not much concerned with the land tenure security of the land as they see themselves as owners of these lands. The reason being that they always had access to their land and there were no perceived tenure insecurity threats. The majority of the smallholder farmers were not worried that they might lose their land in the future as they felt that their land tenure was secured. Although, the majority of farmers had some sense of security they still preferred a freehold tenure system as form of land tenure security. This suggests that there was a sense of insecurity among some of the smallholder farmers caused by their current tenure forms. Majority (66%) of the farmers held their land under freehold whilst leasehold and communal hold farmers constituted 5 % and 29 % respectively. Even though majority had freehold tenure system, they could not use their land as collateral when required for funding from the lending institutions because the title deeds were not registered in their names but those of deceased family members. As a result the majority was constrained by lack of credit and had low income. Lack of cash suggests that the farmers have difficulties in purchasing farm of the survey suggest that the household demographics and socio-economic variables may have an influence on the on-farm investment and on-farm productivity by the smallholder farmers. Furthermore, besides the challenges with land tenure, there are other factors that are likely to influence on-farm investment and on-farm productivity. The results of the survey revealed that smallholder farmers were faced with lot of challenges. These included lack of access to markets, grazing land, credit, farm implements, productions inputs and irrigation water. In addition to this the smallholder farmers were faced with both crops and livestock production constraints. Crop production constraints included lack of access to labour, transport, capital, storage facilities, pests, diseases, lack of management skills and severe drought. Livestock production was constrained by diseases, theft, attack by wild animals, lack of fence in the camps, labour, vaccines, dipping facilities too far and severe drought. For both crop and livestock production diseases and drought were major concerns for smallholder farmers since they were dependent on rainfall for their farming activities. With regards to improvements and investment there was little or not much investment that has been made by the smallholder farmers. One of the reasons mentioned by the farmers as the main cause for little or no investments is the lack of capital to make such improvements or investments. The study also employed empirical analysis through employing on-farm investment and on-farm productivity models of the study on the factors influencing the on-farm investment and on-farm productivity by the smallholder farmers in the study area. In both models, the independent variables were tested for their significance and it was found that some variables were significant whilst others were not. With regards to the dependent variable on-farm investment, household socio-economic factors such as household size, educational levels and farm size, had a positive influence in on-farm investment and were also statistically significant. On the other side, factors such as land tenure security, age, gender, household income and access to markets did not have any influence and were not statistically significant. From the perspective of on-farm productivity variables such as farm size, access to credit and access to extension services had a positive influence. However, variables such as land tenure security, age, household income, educational levels, access to implements, were negatively influencing onfarm productivity by the smallholder farmers. Key words: Land tenure security, smallholder farmers, on-farm investment & on-farm productivity
- Full Text:
- Date Issued: 2014
- Authors: Zwelendaba, Vincent Vusumzi
- Date: 2014
- Subjects: Land tenure -- South Africa -- Eastern Cape , Agricultural productivity -- South Africa -- Eastern Cape , Farms, Small -- South Africa -- Eastern Cape , Rural development -- South Africa -- Eastern Cape , Community development -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MSc Agric (Agricultural Economics)
- Identifier: vital:11230 , http://hdl.handle.net/10353/d1021282 , Land tenure -- South Africa -- Eastern Cape , Agricultural productivity -- South Africa -- Eastern Cape , Farms, Small -- South Africa -- Eastern Cape , Rural development -- South Africa -- Eastern Cape , Community development -- South Africa -- Eastern Cape
- Description: Smallholder agriculture contributes to poverty alleviation through food price reduction and employment creation. Smallholder farmers have the potential of creating employment because they are labour-intensive. Most small holder farmers in the Amathole District practices dual farming system i.e. crops and livestock production. However these farmers are faced by a number of constraints amongst these are land tenure security, lack of capital, drought, diseases, lack of access to markets and production inputs. The objectives of this study were: to investigate land tenure security impact on-farm investment and on-farm productivity by the smallholder farmers; to assess constraints encountered by the smallholder farmers, to identify factors influencing on-farm investment by the smallholder farmers and to identify factors influencing on-farm productivity by the smallholder farmers. Eighty smallholder farmers were interviewed using a structured questionnaire. The data was analyzed using descriptive statistics (frequency, percentages) and regression analyses. Data was for coded and processed for analysis using Statistical Package for Social Sciences (SPSS). The results revealed that generally, the household demographic characteristics have an influence on the decision to investment in the farm thus on farm productivity. These included age, gender, marital status, educational level and household size of the smallholder farmers. However the findings revealed that smallholder farmers were not much concerned with the land tenure security of the land as they see themselves as owners of these lands. The reason being that they always had access to their land and there were no perceived tenure insecurity threats. The majority of the smallholder farmers were not worried that they might lose their land in the future as they felt that their land tenure was secured. Although, the majority of farmers had some sense of security they still preferred a freehold tenure system as form of land tenure security. This suggests that there was a sense of insecurity among some of the smallholder farmers caused by their current tenure forms. Majority (66%) of the farmers held their land under freehold whilst leasehold and communal hold farmers constituted 5 % and 29 % respectively. Even though majority had freehold tenure system, they could not use their land as collateral when required for funding from the lending institutions because the title deeds were not registered in their names but those of deceased family members. As a result the majority was constrained by lack of credit and had low income. Lack of cash suggests that the farmers have difficulties in purchasing farm of the survey suggest that the household demographics and socio-economic variables may have an influence on the on-farm investment and on-farm productivity by the smallholder farmers. Furthermore, besides the challenges with land tenure, there are other factors that are likely to influence on-farm investment and on-farm productivity. The results of the survey revealed that smallholder farmers were faced with lot of challenges. These included lack of access to markets, grazing land, credit, farm implements, productions inputs and irrigation water. In addition to this the smallholder farmers were faced with both crops and livestock production constraints. Crop production constraints included lack of access to labour, transport, capital, storage facilities, pests, diseases, lack of management skills and severe drought. Livestock production was constrained by diseases, theft, attack by wild animals, lack of fence in the camps, labour, vaccines, dipping facilities too far and severe drought. For both crop and livestock production diseases and drought were major concerns for smallholder farmers since they were dependent on rainfall for their farming activities. With regards to improvements and investment there was little or not much investment that has been made by the smallholder farmers. One of the reasons mentioned by the farmers as the main cause for little or no investments is the lack of capital to make such improvements or investments. The study also employed empirical analysis through employing on-farm investment and on-farm productivity models of the study on the factors influencing the on-farm investment and on-farm productivity by the smallholder farmers in the study area. In both models, the independent variables were tested for their significance and it was found that some variables were significant whilst others were not. With regards to the dependent variable on-farm investment, household socio-economic factors such as household size, educational levels and farm size, had a positive influence in on-farm investment and were also statistically significant. On the other side, factors such as land tenure security, age, gender, household income and access to markets did not have any influence and were not statistically significant. From the perspective of on-farm productivity variables such as farm size, access to credit and access to extension services had a positive influence. However, variables such as land tenure security, age, household income, educational levels, access to implements, were negatively influencing onfarm productivity by the smallholder farmers. Key words: Land tenure security, smallholder farmers, on-farm investment & on-farm productivity
- Full Text:
- Date Issued: 2014
Challenges facing teachers in implementing alternative measures of discipline in schools: a case study of five secondary schools in the Umzimkhulu circuit of the Sisonke District in Kwazulu-Natal
- Authors: Zulu, Xolani Wycliff
- Date: 2014
- Subjects: School discipline , Secondary schools , Sisonke District -- Kwazulu-Natal, South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/11260/2393 , vital:41455
- Description: This dissertation is a report on a study that was conducted in rural schools of the Sisonke District in KwaZulu-Natal, a province of South Africa. The study covered the challenges experienced by teachers in implementing the alternative measures of discipline. The study was conducted because the researcher was the head of the disciplinary committee in the school where he was employed and he often dealt with disciplinary problems which usually occurred between the teachers, learners and SMTs. It was important to know from other schools, what problems they faced in implementing the alternative measures of discipline. The study used a qualitative research design in the form of a case study. Purposive sampling was used. The sample comprised 15 SMT members, and 20 post level 1 teachers, and the total number of participants was 35. Data was collected through observations which were followed by interviews. Qualitative methods were used to analyse data. This involved reduction and interpretation of data collected. The findings of the study highlighted the role that could be played by SMTs, teachers, parents, and the Department of Education in the smooth running of the school in dealing with the misunderstandings of alternative measures of discipline and so advance an effective work ethos. The study also illuminated the issue of negligence on the part of SMTs in enforcing the implementation of the alternative measures of discipline. There was a great need for school teachers to be well versed in the general legislation of the Department of Education so as to align themselves with the correct rules and regulations when they deal with disciplinary problems. , Thesis (MEd) -- Faculty of Humanities, Educational Management and Policy, 2014
- Full Text:
- Date Issued: 2014
- Authors: Zulu, Xolani Wycliff
- Date: 2014
- Subjects: School discipline , Secondary schools , Sisonke District -- Kwazulu-Natal, South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/11260/2393 , vital:41455
- Description: This dissertation is a report on a study that was conducted in rural schools of the Sisonke District in KwaZulu-Natal, a province of South Africa. The study covered the challenges experienced by teachers in implementing the alternative measures of discipline. The study was conducted because the researcher was the head of the disciplinary committee in the school where he was employed and he often dealt with disciplinary problems which usually occurred between the teachers, learners and SMTs. It was important to know from other schools, what problems they faced in implementing the alternative measures of discipline. The study used a qualitative research design in the form of a case study. Purposive sampling was used. The sample comprised 15 SMT members, and 20 post level 1 teachers, and the total number of participants was 35. Data was collected through observations which were followed by interviews. Qualitative methods were used to analyse data. This involved reduction and interpretation of data collected. The findings of the study highlighted the role that could be played by SMTs, teachers, parents, and the Department of Education in the smooth running of the school in dealing with the misunderstandings of alternative measures of discipline and so advance an effective work ethos. The study also illuminated the issue of negligence on the part of SMTs in enforcing the implementation of the alternative measures of discipline. There was a great need for school teachers to be well versed in the general legislation of the Department of Education so as to align themselves with the correct rules and regulations when they deal with disciplinary problems. , Thesis (MEd) -- Faculty of Humanities, Educational Management and Policy, 2014
- Full Text:
- Date Issued: 2014
Redefining success : social justice and the ends of business
- Authors: Zorn, Gwendolyn Philippa
- Date: 2014
- Subjects: Success Social justice Success in business Social responsibility of business Business ethics Corporate profits
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:2745 , http://hdl.handle.net/10962/d1012061
- Description: Success in business is for the most part defined in financial terms and, because of this, business operations are almost entirely, if not entirely, directed to this end. The principle behind this rationale has been informed by the thought that the best contribution businesses can make to social justice is to focus on the bottom line. By appealing to enlightened self-interest and the high premium people place on freedom, neoliberal economists like Milton Friedman and Friedrich Hayek argue that maximising profits is necessarily socially responsible. And, moreover, that not to pursue this end is socially irresponsible. Social responsibility is the ultimate justification that thinkers such as Friedman and Hayek appeal to when claiming that the business of business is to maximise profit. Yet this position is internally inconsistent. The position is ultimately justified by what is socially just but this means that in fact social justice, and not profit-making, ought to be the end of business. I shall argue that taking this commitment seriously involves rejecting the idea that the aim of business is to maximise profits. This is not to say that businesses should not make profits, rather it implies that this feature is not what ultimately makes them successful. The central contribution of this project is to resolve the contradictions embedded in the traditional approach to business by arguing that the primary aim of business is the promotion of social justice. To this end success in business needs to be redefined so that it reflects the achievement of its ultimate ends and not simply its instrumental means (profit) to the realisation of these aims. We ought then to revise our fundamental assumptions about the structures and policies that are necessary for business to achieve its real end of social justice.
- Full Text:
- Date Issued: 2014
- Authors: Zorn, Gwendolyn Philippa
- Date: 2014
- Subjects: Success Social justice Success in business Social responsibility of business Business ethics Corporate profits
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:2745 , http://hdl.handle.net/10962/d1012061
- Description: Success in business is for the most part defined in financial terms and, because of this, business operations are almost entirely, if not entirely, directed to this end. The principle behind this rationale has been informed by the thought that the best contribution businesses can make to social justice is to focus on the bottom line. By appealing to enlightened self-interest and the high premium people place on freedom, neoliberal economists like Milton Friedman and Friedrich Hayek argue that maximising profits is necessarily socially responsible. And, moreover, that not to pursue this end is socially irresponsible. Social responsibility is the ultimate justification that thinkers such as Friedman and Hayek appeal to when claiming that the business of business is to maximise profit. Yet this position is internally inconsistent. The position is ultimately justified by what is socially just but this means that in fact social justice, and not profit-making, ought to be the end of business. I shall argue that taking this commitment seriously involves rejecting the idea that the aim of business is to maximise profits. This is not to say that businesses should not make profits, rather it implies that this feature is not what ultimately makes them successful. The central contribution of this project is to resolve the contradictions embedded in the traditional approach to business by arguing that the primary aim of business is the promotion of social justice. To this end success in business needs to be redefined so that it reflects the achievement of its ultimate ends and not simply its instrumental means (profit) to the realisation of these aims. We ought then to revise our fundamental assumptions about the structures and policies that are necessary for business to achieve its real end of social justice.
- Full Text:
- Date Issued: 2014
A critical analysis of service delivery system in the health institutions: a case study of Queenstown Private Hospital in Chris Hani District 2013
- Authors: Zonke, Noncendo
- Date: 2014
- Language: English
- Type: Thesis , Masters , MPA
- Identifier: vital:11709 , http://hdl.handle.net/10353/d1015240
- Description: Service delivery challenges have been reported between from the health care industry more especially in the Eastern Cape Province this is due to a number of factors such as job satisfaction, productivity, absenteeism and turnover among healthcare employees and as such it affects employees’ organizational commitment and the quality of healthcare services. The aim of the study was to determine the factors influencing job satisfaction among healthcare professionals at Queenstown Private Hospital in relation to the service delivery. The study was conducted among 30 participants. Self-administered questionnaires were used to collect data from the participants. Data was then analysed using statistical tools such as pie charts and graphs. The results showed a high level of job satisfaction result in optimum service delivery in the service industry, more especially in the Queenstown private hospital. Almost 90% of participants were satisfied with their jobs, and there was a high level association between job satisfaction and socio-demographic characteristics. Variables such as opportunity to develop, responsibility, patient care and staff relations were found to be significantly influencing job satisfaction and there was a significant positive medium association between job satisfaction and opportunity to develop,responsibility, patient care and staff relations for both clinical and clinical support staff and consequently the employee performance in their jobs, which resulted in the improved delivery of health care in the hospital at all the times. Satisfaction with one’s job can affect not only motivation at work but also career decisions, relationship with others and personal health. Job satisfaction is also an essential part of ensuring high quality care. Dissatisfied healthcare providers give poor quality, less efficient care.
- Full Text:
- Date Issued: 2014
- Authors: Zonke, Noncendo
- Date: 2014
- Language: English
- Type: Thesis , Masters , MPA
- Identifier: vital:11709 , http://hdl.handle.net/10353/d1015240
- Description: Service delivery challenges have been reported between from the health care industry more especially in the Eastern Cape Province this is due to a number of factors such as job satisfaction, productivity, absenteeism and turnover among healthcare employees and as such it affects employees’ organizational commitment and the quality of healthcare services. The aim of the study was to determine the factors influencing job satisfaction among healthcare professionals at Queenstown Private Hospital in relation to the service delivery. The study was conducted among 30 participants. Self-administered questionnaires were used to collect data from the participants. Data was then analysed using statistical tools such as pie charts and graphs. The results showed a high level of job satisfaction result in optimum service delivery in the service industry, more especially in the Queenstown private hospital. Almost 90% of participants were satisfied with their jobs, and there was a high level association between job satisfaction and socio-demographic characteristics. Variables such as opportunity to develop, responsibility, patient care and staff relations were found to be significantly influencing job satisfaction and there was a significant positive medium association between job satisfaction and opportunity to develop,responsibility, patient care and staff relations for both clinical and clinical support staff and consequently the employee performance in their jobs, which resulted in the improved delivery of health care in the hospital at all the times. Satisfaction with one’s job can affect not only motivation at work but also career decisions, relationship with others and personal health. Job satisfaction is also an essential part of ensuring high quality care. Dissatisfied healthcare providers give poor quality, less efficient care.
- Full Text:
- Date Issued: 2014
Development and assessment of sustained release stavudine loaded microparticles
- Authors: Zindove, Chiedza Cathrine
- Date: 2014
- Language: English
- Type: text , Thesis , Masters , MPharm
- Identifier: http://hdl.handle.net/10962/54722 , vital:26603
- Description:
Stavudine (D4T) has been used as first line treatment for HIV/AIDS and is part of highly active anti retroviral treatment (HAART). It is an affordable medicine and its use is beneficial in resource limited settings. However D4T exhibits dose dependent side effects that may lead to non-adherence in patients. This study was undertaken to formulate, develop and manufacture a dosage form that could reduce dose dependent side effects by decreasing the dose of D4T but still exhibit antiretroviral (ARV) activity. The use of sustained release (SR) formulations of D4T that ensure constant levels of the D4T in the body would not only optimize therapy but also reduce the incidence of side effects thereby increasing patient adherence. SR microparticles containing 30mg D4T were manufactured and loaded into size 3 hard gelatine capsules prior to analysis. The D4T microparticles were manufactured by microencapsulation using non-aqueous oil-in-oil solvent evaporation approach. D4T-excipient, excipient-excipient interactions and D4T purity were assessed using Infrared Spectroscopy (IR), Differential Scanning Calorimetry (DSC) and Thermogravimetric Analysis (TGA). Copolymers synthesized from acrylic and methacrylic acid esters viz., Eudragit® RSPO and S100 were used as rate retardant materials and the effect of microcrystalline cellulose (Avicel® PH102) on the microparticles was also investigated. Magnesium stearate was used as a droplet stabilizer and n-hexane was added to harden the microspheres formed in a liquid paraffin continuous phase. The microparticles were optimized using a Box Behnken design and Response Surface Methodology (RSM). The microparticles were characterized in terms of their flow properties and encapsulation efficiency (% EE), in addition to visualization of the surface morphology with Scanning Electron Microscopy. In vitro D4T release studies were performed using USP Apparatus III in media of different pH and the samples were analysed using a validated High Performance Liquid Chromatographic (HPLC) method with ultraviolet (UV) detection that had been developed and optimized using a Central Composite Design (CCD). The method was validated according to ICH guidelines. The IR spectra and DSC thermographs revealed that D4T exhibited thermal stability and there was no evidence of D4T-excipient and excipient-excipient interactions. The microparticles that were produced were white, free flowing and were obtained in a high yield with high encapsulation efficiency. Scanning Electron Microscopy studies revealed that the microparticles were spherical and porous in nature. In vitro D4T release extended to 12 hours and the mechanism of release was established using model dependent methods by fitting the data to a Zero order, First order, Higuchi and Hixson Crowell model. It was observed that the mechanism of D4T release was diffusion-controlled and that the data was best fitted to the Higuchi model with correlation coefficients > 0.9. The release mechanism was confirmed using the Korsmeyer-Peppas model that revealed that most of the formulations exhibited anomalous transport kinetics with the release exponent, n, ranging from 0.5
- Full Text:
- Date Issued: 2014
- Authors: Zindove, Chiedza Cathrine
- Date: 2014
- Language: English
- Type: text , Thesis , Masters , MPharm
- Identifier: http://hdl.handle.net/10962/54722 , vital:26603
- Description:
Stavudine (D4T) has been used as first line treatment for HIV/AIDS and is part of highly active anti retroviral treatment (HAART). It is an affordable medicine and its use is beneficial in resource limited settings. However D4T exhibits dose dependent side effects that may lead to non-adherence in patients. This study was undertaken to formulate, develop and manufacture a dosage form that could reduce dose dependent side effects by decreasing the dose of D4T but still exhibit antiretroviral (ARV) activity. The use of sustained release (SR) formulations of D4T that ensure constant levels of the D4T in the body would not only optimize therapy but also reduce the incidence of side effects thereby increasing patient adherence. SR microparticles containing 30mg D4T were manufactured and loaded into size 3 hard gelatine capsules prior to analysis. The D4T microparticles were manufactured by microencapsulation using non-aqueous oil-in-oil solvent evaporation approach. D4T-excipient, excipient-excipient interactions and D4T purity were assessed using Infrared Spectroscopy (IR), Differential Scanning Calorimetry (DSC) and Thermogravimetric Analysis (TGA). Copolymers synthesized from acrylic and methacrylic acid esters viz., Eudragit® RSPO and S100 were used as rate retardant materials and the effect of microcrystalline cellulose (Avicel® PH102) on the microparticles was also investigated. Magnesium stearate was used as a droplet stabilizer and n-hexane was added to harden the microspheres formed in a liquid paraffin continuous phase. The microparticles were optimized using a Box Behnken design and Response Surface Methodology (RSM). The microparticles were characterized in terms of their flow properties and encapsulation efficiency (% EE), in addition to visualization of the surface morphology with Scanning Electron Microscopy. In vitro D4T release studies were performed using USP Apparatus III in media of different pH and the samples were analysed using a validated High Performance Liquid Chromatographic (HPLC) method with ultraviolet (UV) detection that had been developed and optimized using a Central Composite Design (CCD). The method was validated according to ICH guidelines. The IR spectra and DSC thermographs revealed that D4T exhibited thermal stability and there was no evidence of D4T-excipient and excipient-excipient interactions. The microparticles that were produced were white, free flowing and were obtained in a high yield with high encapsulation efficiency. Scanning Electron Microscopy studies revealed that the microparticles were spherical and porous in nature. In vitro D4T release extended to 12 hours and the mechanism of release was established using model dependent methods by fitting the data to a Zero order, First order, Higuchi and Hixson Crowell model. It was observed that the mechanism of D4T release was diffusion-controlled and that the data was best fitted to the Higuchi model with correlation coefficients > 0.9. The release mechanism was confirmed using the Korsmeyer-Peppas model that revealed that most of the formulations exhibited anomalous transport kinetics with the release exponent, n, ranging from 0.5
- Full Text:
- Date Issued: 2014
Challenges faced by traditional healers when treating people living with HIV and AIDS: the case of Intsika Municipality, Eastern Cape province
- Authors: Zimba, Zibonele France
- Date: 2014
- Subjects: People with HIV and AIDS disease -- Healers -- South Africa , Traditional medicine -- South Africa , HIV infections -- Treatment -- South Africa , AIDS (Disease) -- Treatment -- South Africa
- Language: English
- Type: Thesis , Masters , M SW
- Identifier: vital:11768 , http://hdl.handle.net/10353/d1015357 , People with HIV and AIDS disease -- Healers -- South Africa , Traditional medicine -- South Africa , HIV infections -- Treatment -- South Africa , AIDS (Disease) -- Treatment -- South Africa
- Description: The aim of the study was to examine the procedures followed by traditional healers treating people living with HIV and AIDS in the Instika Municipality and the challenges faced by them in this endeavour. Using the qualitative research method, in-depth interviews and focus group discussions were conducted with twenty traditional healers. Among the significant findings of this study were the hardships encountered by traditional healers in terms of finance, the transport needed to collect medicinal plants, the shortage of medicinal plants, the lack of co-operation from the formal health care sector and the discrimination and abuse suffered at the hands of members of the community, with Christians and members of the SAPS being among the chief antagonists. It is also acknowledged in this study that traditional healers have been trained by the Department of Health concerning issues of hygiene and that traditional healers have knowledge of the symptoms of HIV and AIDS. It can therefore be concluded that traditional healers have a significant role to play in preventing the spread of HIV and AIDS if they employ preventative measures such as the use of protective gloves and limiting the use of a blade to one patient only. However, traditional healers are not supplied with safety kits or condoms to distribute to patients who consult them for treatment of STIs.
- Full Text:
- Date Issued: 2014
- Authors: Zimba, Zibonele France
- Date: 2014
- Subjects: People with HIV and AIDS disease -- Healers -- South Africa , Traditional medicine -- South Africa , HIV infections -- Treatment -- South Africa , AIDS (Disease) -- Treatment -- South Africa
- Language: English
- Type: Thesis , Masters , M SW
- Identifier: vital:11768 , http://hdl.handle.net/10353/d1015357 , People with HIV and AIDS disease -- Healers -- South Africa , Traditional medicine -- South Africa , HIV infections -- Treatment -- South Africa , AIDS (Disease) -- Treatment -- South Africa
- Description: The aim of the study was to examine the procedures followed by traditional healers treating people living with HIV and AIDS in the Instika Municipality and the challenges faced by them in this endeavour. Using the qualitative research method, in-depth interviews and focus group discussions were conducted with twenty traditional healers. Among the significant findings of this study were the hardships encountered by traditional healers in terms of finance, the transport needed to collect medicinal plants, the shortage of medicinal plants, the lack of co-operation from the formal health care sector and the discrimination and abuse suffered at the hands of members of the community, with Christians and members of the SAPS being among the chief antagonists. It is also acknowledged in this study that traditional healers have been trained by the Department of Health concerning issues of hygiene and that traditional healers have knowledge of the symptoms of HIV and AIDS. It can therefore be concluded that traditional healers have a significant role to play in preventing the spread of HIV and AIDS if they employ preventative measures such as the use of protective gloves and limiting the use of a blade to one patient only. However, traditional healers are not supplied with safety kits or condoms to distribute to patients who consult them for treatment of STIs.
- Full Text:
- Date Issued: 2014
Development of a bench scale single batch biomass to liquid fuel facility
- Authors: Zhang, Yusheng
- Date: 2014
- Subjects: Biomass energy , Renewable energy sources , Energy conversion , Electric power production
- Language: English
- Type: Thesis , Masters , MSc (Chemistry)
- Identifier: http://hdl.handle.net/10353/811 , vital:26499 , Biomass energy , Renewable energy sources , Energy conversion , Electric power production
- Description: The research described in this dissertation was motivated by the global demand for energy that is not dependent on coal, oil, natural gas and other non-renewable fossil fuels. The technology used in this project is related to the use of biomass to produce a viable alternative to conventional sources of fuel. A bench scale biomass to liquid (BTL) facility was built and tested. This produced results confirming the feasibility of the BTL process. The findings of the pilot study outlined in this dissertation justified the conclusion that the next step will be to expand the capacity and productivity of the BTL pilot plant to an industrial scale. Biomass comes from a variety of renewable sources that are readily available. In this case, the material used in the fixed bed biomass gasification facility to generate wood gas was agricultural and forestry waste, such as straw and wood chips. The gasifier had the capacity to produce up to 10 cubic metres/hr of gas with a carbon monoxide and hydrogen content of between 20–40% by volume, when it was operated at ambient pressure and with air as the oxidizer. The gas, produced at a temperature above 700º C, was cooled in a quench/water scrubber in order to remove most of the mechanical impurities (tars and water-soluble inorganic particles), condensed and dried with corn cobs before being compressed in cylinders at over 100 bar (g) for use in the Fischer-Tropsch Synthesis (FTS). The syngas was subjected further to a series of refining processes which included removal of sulphur and oxygen. The sulphur removal technology chosen entailed applying modified activated carbon to adsorb H2S with the help of hydrolysis in order to convert organic sulphur impurities into H2S which reduced the sulphur content of the gas to less than 5 ppbv. Supported cobalt catalyst (100 grams), were loaded into a single-tube fixed bed FT reactor with an inner diameter of 50 mm. The reactor was fitted with a heating jacket through which, heated oil ran to cool the reactor during a normal reaction occurring at < 250 ºC, while nitrogen was used in the heating jacket during reduction, which occurred at temperatures up ~ 350 ºC. The FTS reaction was carried out at different pressures and temperatures. Liquid and wax products were produced from the facility. The properties of the liquid and solid hydrocarbons produced were found to be the same as FT products from other feed stocks, such as natural gas and coal.
- Full Text:
- Date Issued: 2014
- Authors: Zhang, Yusheng
- Date: 2014
- Subjects: Biomass energy , Renewable energy sources , Energy conversion , Electric power production
- Language: English
- Type: Thesis , Masters , MSc (Chemistry)
- Identifier: http://hdl.handle.net/10353/811 , vital:26499 , Biomass energy , Renewable energy sources , Energy conversion , Electric power production
- Description: The research described in this dissertation was motivated by the global demand for energy that is not dependent on coal, oil, natural gas and other non-renewable fossil fuels. The technology used in this project is related to the use of biomass to produce a viable alternative to conventional sources of fuel. A bench scale biomass to liquid (BTL) facility was built and tested. This produced results confirming the feasibility of the BTL process. The findings of the pilot study outlined in this dissertation justified the conclusion that the next step will be to expand the capacity and productivity of the BTL pilot plant to an industrial scale. Biomass comes from a variety of renewable sources that are readily available. In this case, the material used in the fixed bed biomass gasification facility to generate wood gas was agricultural and forestry waste, such as straw and wood chips. The gasifier had the capacity to produce up to 10 cubic metres/hr of gas with a carbon monoxide and hydrogen content of between 20–40% by volume, when it was operated at ambient pressure and with air as the oxidizer. The gas, produced at a temperature above 700º C, was cooled in a quench/water scrubber in order to remove most of the mechanical impurities (tars and water-soluble inorganic particles), condensed and dried with corn cobs before being compressed in cylinders at over 100 bar (g) for use in the Fischer-Tropsch Synthesis (FTS). The syngas was subjected further to a series of refining processes which included removal of sulphur and oxygen. The sulphur removal technology chosen entailed applying modified activated carbon to adsorb H2S with the help of hydrolysis in order to convert organic sulphur impurities into H2S which reduced the sulphur content of the gas to less than 5 ppbv. Supported cobalt catalyst (100 grams), were loaded into a single-tube fixed bed FT reactor with an inner diameter of 50 mm. The reactor was fitted with a heating jacket through which, heated oil ran to cool the reactor during a normal reaction occurring at < 250 ºC, while nitrogen was used in the heating jacket during reduction, which occurred at temperatures up ~ 350 ºC. The FTS reaction was carried out at different pressures and temperatures. Liquid and wax products were produced from the facility. The properties of the liquid and solid hydrocarbons produced were found to be the same as FT products from other feed stocks, such as natural gas and coal.
- Full Text:
- Date Issued: 2014
The sustainability of health committees in Nelson Mandela Bay
- Authors: Zhakata, Chikomborero
- Date: 2014
- Subjects: Health services administration , Community health services
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9151 , http://hdl.handle.net/10948/d1019704
- Description: Primary health care is pivotal to the growth of a country’s economy by improving the health and social well-being of its people. Several efforts and structures have been put in place to ensure that all South Africans have access to health facilities as well as representation in the health facilities, just as community members are represented in schools and other boards. Health committees play an important and integral role to the community and health facilities by being mediators between the community and the health facility (Padarath &Friedman, 2008). The Eastern Cape is one of the provinces that has health committees that are fully functional and a number of factors including the collaboration of key stakeholders (facility managers, community members, clinic staff and ward councillors) contribute to why health committees have been operational in the Eastern Cape(Padarath &Friedman , 2008). It becomes critical to investigate factors that sustain health committees in Nelson Mandela Bay. This chapter introduces the research topic, purpose, rationale and background as well as the objectives of the study. The research focuses on investigating the sustainability of health committees in Nelson Mandela Bay therefore making it critical to define the term sustainability. Conceptualizing sustainability has been ongoing with various definitions from learners from different backgrounds. Sustainability as a concept emanates from different dimensions namely, scientific, political economic and indigenous dimension. Sustainability has been described by scholars as a state of well-being and as an evolutionary process (Dimitrov, 2010). Sustainability is regarded as a state of well being whereby humans can live in co-exist with the natural world, this definition takes into account issues to do with good health , cultural identity, personal security and freedom of choice. Sustainability- well being brings out a lot of questions and problems in identifying the fundamentals values of sustainability. It is continuously debated amoung scholars if sustainability of well being pertains only to the health conditions of human beings or it should be extended to others (Dimitrov, 2010) “Sustainability that is restricted to the well being of humans is related to Notions about security of individual/community health together with financial security together with financial security; the planet is regarded as a resource to further this end (Dimitrov, 2010:4) If however well-being definitions of sustainability are construed to preserving and protecting the environment as well as biodiversity of other species (plant and animals) then the normative definitions of sustainability from this viewpoint are tendered with notions of global Environmental stability, ecological considerations and security of ecosystems” (Dimitrov, 2010:4).
- Full Text:
- Date Issued: 2014
- Authors: Zhakata, Chikomborero
- Date: 2014
- Subjects: Health services administration , Community health services
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:9151 , http://hdl.handle.net/10948/d1019704
- Description: Primary health care is pivotal to the growth of a country’s economy by improving the health and social well-being of its people. Several efforts and structures have been put in place to ensure that all South Africans have access to health facilities as well as representation in the health facilities, just as community members are represented in schools and other boards. Health committees play an important and integral role to the community and health facilities by being mediators between the community and the health facility (Padarath &Friedman, 2008). The Eastern Cape is one of the provinces that has health committees that are fully functional and a number of factors including the collaboration of key stakeholders (facility managers, community members, clinic staff and ward councillors) contribute to why health committees have been operational in the Eastern Cape(Padarath &Friedman , 2008). It becomes critical to investigate factors that sustain health committees in Nelson Mandela Bay. This chapter introduces the research topic, purpose, rationale and background as well as the objectives of the study. The research focuses on investigating the sustainability of health committees in Nelson Mandela Bay therefore making it critical to define the term sustainability. Conceptualizing sustainability has been ongoing with various definitions from learners from different backgrounds. Sustainability as a concept emanates from different dimensions namely, scientific, political economic and indigenous dimension. Sustainability has been described by scholars as a state of well-being and as an evolutionary process (Dimitrov, 2010). Sustainability is regarded as a state of well being whereby humans can live in co-exist with the natural world, this definition takes into account issues to do with good health , cultural identity, personal security and freedom of choice. Sustainability- well being brings out a lot of questions and problems in identifying the fundamentals values of sustainability. It is continuously debated amoung scholars if sustainability of well being pertains only to the health conditions of human beings or it should be extended to others (Dimitrov, 2010) “Sustainability that is restricted to the well being of humans is related to Notions about security of individual/community health together with financial security together with financial security; the planet is regarded as a resource to further this end (Dimitrov, 2010:4) If however well-being definitions of sustainability are construed to preserving and protecting the environment as well as biodiversity of other species (plant and animals) then the normative definitions of sustainability from this viewpoint are tendered with notions of global Environmental stability, ecological considerations and security of ecosystems” (Dimitrov, 2010:4).
- Full Text:
- Date Issued: 2014
The role of local economic development on poverty alleviation in Nelson Mandela Metropolitan Municipality
- Zazaza-Msengana, Andisiwe Andriesa
- Authors: Zazaza-Msengana, Andisiwe Andriesa
- Date: 2014
- Subjects: Economic development projects -- South Africa -- Nelson Mandela Bay Municipality , Poverty -- Economic aspects -- South Africa -- Nelson Mandela Bay Municipality
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/5922 , vital:21014
- Description: Local economic development in South Africa has been a term used to define interventions to promote economic development in a specific area ranging from small neighborhood through to a region or district. Approaches to LED have developed and changed as local economies have had to respond to changing impacts in the global economy. Local economic development projects range from simple and small to larger and more complex actions and programmes. They are aimed at changing local socio-economic relationships fundamentally over time. At the core of LED is the need to involve local people and institutions in the development of their local economies by focusing on opportunities for economic growth, employment creation through empowerment as well as social and economic transformation. Local economic development is most importantly about people working together to achieve sustainable economic growth that brings economic benefits and quality of life improvements for all in the local community. In an attempt to assess the role of LED on poverty alleviation in NMBM three LED projects were identified. Participants were members of the projects. The study found that, indeed LED projects do have a positive impact in changing socio- economic conditions of the local people. LED initiatives play a role towards poverty alleviation and economic development since they contribute towards job creation, skills transfer, infrastructure development and improving livelihoods of the people community.
- Full Text:
- Date Issued: 2014
- Authors: Zazaza-Msengana, Andisiwe Andriesa
- Date: 2014
- Subjects: Economic development projects -- South Africa -- Nelson Mandela Bay Municipality , Poverty -- Economic aspects -- South Africa -- Nelson Mandela Bay Municipality
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/5922 , vital:21014
- Description: Local economic development in South Africa has been a term used to define interventions to promote economic development in a specific area ranging from small neighborhood through to a region or district. Approaches to LED have developed and changed as local economies have had to respond to changing impacts in the global economy. Local economic development projects range from simple and small to larger and more complex actions and programmes. They are aimed at changing local socio-economic relationships fundamentally over time. At the core of LED is the need to involve local people and institutions in the development of their local economies by focusing on opportunities for economic growth, employment creation through empowerment as well as social and economic transformation. Local economic development is most importantly about people working together to achieve sustainable economic growth that brings economic benefits and quality of life improvements for all in the local community. In an attempt to assess the role of LED on poverty alleviation in NMBM three LED projects were identified. Participants were members of the projects. The study found that, indeed LED projects do have a positive impact in changing socio- economic conditions of the local people. LED initiatives play a role towards poverty alleviation and economic development since they contribute towards job creation, skills transfer, infrastructure development and improving livelihoods of the people community.
- Full Text:
- Date Issued: 2014
A case study on the role of excel as a teaching and learning tool in influencing learners' interpretation of functions
- Authors: Zakumba, Lwazi Xolisile
- Date: 2014
- Subjects: Microsoft Excel (Computer file) , Computer-assisted instruction , Mathematics -- Study and teaching (Secondary)
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:9455 , http://hdl.handle.net/10948/d1018756
- Description: The aim of this study was to investigate the role Excel could play in influencing Mathematics and Mathematical literacy learners’ interpretation of functions and their attitude towards Mathematics. I used a Mathematical Graphical Diagnostic (MGD) test, an attitude questionnaire, a reflective questionnaire and semi-structured interviews as instruments. The MGD test and the attitude questionnaire were given to 72 volunteer grade 11 learners at a former Model C school in Port Elizabeth, in the Eastern Cape. This group included 50 pure Mathematics learners and 22 Mathematical literacy learners. From this group, a smaller group of 10 learners further took part in the rest of the study were they went through an intervention were Excel was used as a teaching tool, covering concepts concerning functions. This group included 6 pure Mathematics and 4 Mathematical literacy learners. The 10 learners then re-wrote the MDG test and refilled the attitude questionnaire after the intervention. A reflective questionnaire was administered to the 10 learners after the intervention, with 5 learners from the 10 undergoing interviews in order to meet the objectives of the study. The administration of the MDG test and attitude questionnaire, interviews and reflective questionnaire enabled me to explore the relationship between learner performance and their attitude towards Mathematics as a subject, as well as the comparing the attitudes and performances between pure Mathematics and Mathematical Literacy learners. The study followed a qualitative research design, with an element of quantitative research. The qualitative data yielded findings that revealed the effectiveness of using Excel in teaching functions while the quantitative data revealed the difference in attitude and ability between pure Mathematics and Mathematical Literacy leaners. The findings of the study revealed that Excel played a major role in improving pure Mathematics learners’ results but not those of the Mathematical Literacy learners. The study also showed that technology does not necessarily impact on learners’ attitudes positively.
- Full Text:
- Date Issued: 2014
- Authors: Zakumba, Lwazi Xolisile
- Date: 2014
- Subjects: Microsoft Excel (Computer file) , Computer-assisted instruction , Mathematics -- Study and teaching (Secondary)
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:9455 , http://hdl.handle.net/10948/d1018756
- Description: The aim of this study was to investigate the role Excel could play in influencing Mathematics and Mathematical literacy learners’ interpretation of functions and their attitude towards Mathematics. I used a Mathematical Graphical Diagnostic (MGD) test, an attitude questionnaire, a reflective questionnaire and semi-structured interviews as instruments. The MGD test and the attitude questionnaire were given to 72 volunteer grade 11 learners at a former Model C school in Port Elizabeth, in the Eastern Cape. This group included 50 pure Mathematics learners and 22 Mathematical literacy learners. From this group, a smaller group of 10 learners further took part in the rest of the study were they went through an intervention were Excel was used as a teaching tool, covering concepts concerning functions. This group included 6 pure Mathematics and 4 Mathematical literacy learners. The 10 learners then re-wrote the MDG test and refilled the attitude questionnaire after the intervention. A reflective questionnaire was administered to the 10 learners after the intervention, with 5 learners from the 10 undergoing interviews in order to meet the objectives of the study. The administration of the MDG test and attitude questionnaire, interviews and reflective questionnaire enabled me to explore the relationship between learner performance and their attitude towards Mathematics as a subject, as well as the comparing the attitudes and performances between pure Mathematics and Mathematical Literacy learners. The study followed a qualitative research design, with an element of quantitative research. The qualitative data yielded findings that revealed the effectiveness of using Excel in teaching functions while the quantitative data revealed the difference in attitude and ability between pure Mathematics and Mathematical Literacy leaners. The findings of the study revealed that Excel played a major role in improving pure Mathematics learners’ results but not those of the Mathematical Literacy learners. The study also showed that technology does not necessarily impact on learners’ attitudes positively.
- Full Text:
- Date Issued: 2014
Retention strategies for medical doctors in a Port Elizabeth Hospital complex
- Authors: Yusuff, Toyeeb
- Date: 2014
- Subjects: Employee retention -- South Africa -- Port Elizabeth , Physicians -- Recruiting -- South Africa -- Port Elizabeth
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/8856 , vital:26436
- Description: The aim of this research is to investigate the factors identified as significant in increasing the retention of medical doctors employed in Port Elizabeth hospital complex (PEHC) in the Eastern Cape, South Africa. Medical practitioners of PEHC are providing the needed critical clinical services and are believed to be the strength of tertiary health services in the Eastern Cape, providing world class treatment to the public. Recruitment and retention of talented medical practitioners, then, is in the best interests of the Department of Health. Demotivated staffs are more likely to leave their jobs for better opportunities, and therefore efforts must be geared towards retaining them. This research investigates the independent factors identified. They include the management style, risk exposure, the working environment, the work overload, and the benefits associated with retaining of medical practitioners in PEHC. The results of this study revealed that the following factors influence the talent management and retention of doctors in the hospital complex: a management style that appreciates and recognises staff, a risk-free work environment, a flexible and balanced life, a reasonable work load, and the attitude of immediate supervisors. The results of this study will add to the guidelines and retention strategies already in place by the Department of Health, Eastern Cape. The senior management and policy makers could use the recommendations revealed in this study for an efficient human resources policy. However, future research still needs to be done in the area of providing employment for spouses of members of staff especially on the reward system and the recognition of employees in the organization.
- Full Text:
- Date Issued: 2014
- Authors: Yusuff, Toyeeb
- Date: 2014
- Subjects: Employee retention -- South Africa -- Port Elizabeth , Physicians -- Recruiting -- South Africa -- Port Elizabeth
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/8856 , vital:26436
- Description: The aim of this research is to investigate the factors identified as significant in increasing the retention of medical doctors employed in Port Elizabeth hospital complex (PEHC) in the Eastern Cape, South Africa. Medical practitioners of PEHC are providing the needed critical clinical services and are believed to be the strength of tertiary health services in the Eastern Cape, providing world class treatment to the public. Recruitment and retention of talented medical practitioners, then, is in the best interests of the Department of Health. Demotivated staffs are more likely to leave their jobs for better opportunities, and therefore efforts must be geared towards retaining them. This research investigates the independent factors identified. They include the management style, risk exposure, the working environment, the work overload, and the benefits associated with retaining of medical practitioners in PEHC. The results of this study revealed that the following factors influence the talent management and retention of doctors in the hospital complex: a management style that appreciates and recognises staff, a risk-free work environment, a flexible and balanced life, a reasonable work load, and the attitude of immediate supervisors. The results of this study will add to the guidelines and retention strategies already in place by the Department of Health, Eastern Cape. The senior management and policy makers could use the recommendations revealed in this study for an efficient human resources policy. However, future research still needs to be done in the area of providing employment for spouses of members of staff especially on the reward system and the recognition of employees in the organization.
- Full Text:
- Date Issued: 2014
Towards the modeling of indigenous poultry production in the Eastern Cape Province, South Africa: characterization and extension evaluation for poverty reduction
- Yusuf, Shehu Folaranmi Gbolahan Shehu
- Authors: Yusuf, Shehu Folaranmi Gbolahan Shehu
- Date: 2014
- Subjects: Poultry -- Breeding -- South Africa -- Eastern Cape , Chickens -- Breeding -- South Africa -- Eastern Cape , Economic development -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Doctoral , PhD (Agricultural Economics)
- Identifier: vital:11223 , http://hdl.handle.net/10353/d1019833 , Poultry -- Breeding -- South Africa -- Eastern Cape , Chickens -- Breeding -- South Africa -- Eastern Cape , Economic development -- South Africa -- Eastern Cape
- Description: Poverty remains a critical issue mostly in the rural South Africa. Various initiatives, policies and programs have been enacted by the government with attempting to reduce poverty at the national and provincial levels; poverty is yet to be abated. The target of the Millennium Development Goal 1 (MDG1) of halving poverty by the year 2015 notwithstanding, poverty remains a threat to quality livelihoods. Agriculture has continued to be one of the pillars of government efforts to address poverty. However, in livestock production interventions, efforts of government had largely been on cattle, sheep, goats, pigs and exotic poultry with little attention being given to indigenous poultry production (IPP). This study explores the option of using IPP to address rural poverty by capitalizing on its minimal inputs while recognizing its prevalence in a variety of households. The study addresses the characterization of the IPP from the perspectives of housing, feeding, healthcare management, breeding and marketing options.Skill competencies of the indigenous poultry farmers (IPFs) and the Agricultural Development Technicians (ADTs) were examined. This study reviewed poultry models in different parts of the world with special attention to Africa. The human resource development program of the department of rural development and agrarian reform was discussed. The study employed the use of multi-methods approach, the quantitative and qualitative research methodologies. Descriptive statistical analysis, frequent count, percentage, means, standard deviation, chisquare, and principal component analysis was used in the quantitative data analysis while the “open social system” was used for the qualitative methodology. Findings revealed that IPFs face some challenges among which are, the poor housing that exposed the birds to inclement weather, predator attacks and stock theft, high mortality of chicks after hatching and expensive feed for the flock. The IPFs showed competencies in nine skill items that included ability to identify chicken predators (x=3.92) and high yielding chickens (x=3.79); control of predators(x=3.77); methods of using ethno veterinary drugs to treat chicken diseases and pests (x=3.72), and identify signs of diseases (x=3.69), among others. However, the ADTs did not show any competency in any of the 32 skills items. The principal component analysis with Varimax rotation was performed to ascertain the dimensionality of the measures. Six factors with eigen value of >1, which accounted for 77.317% were extracted, with each factor loading ranging from 0.523 to 0.93. Factor loading after rotation that emerged on the same component was described; as brooding, shelter and care of the chicks; predators and healthcare; hygiene and litter management; feeds and feeding stuff; and record keeping and marketing. The findings on the human resource development revealed that staff meetings were the most common method of capacity development. This was followed by in-service-training, formal study, workshop, and on the job training. The farmers’ field school and study tours were sparingly used. However, respondents were in favor of on-site training, staff meetings, formal study and in-service training. The findings on the appropriate model suggest a theoretical indigenous poultry production model (IPPM) for the Eastern Cape Province (ECP). The “open social system” was used to develop a framework for an indigenous poultry cooperative society (to be known as Abafuyi Benkukhu Zemveli [ABZ]). This was meant to create a binding force for capacity development, a strong economic foundation through equity contributions, creation of marketing channels, and the development of a concept of ‘‘our own'' product in the market. Lastly, the study offers options for a training program that would accommodate the new initiatives, with a strong capacity development training approach. In this context, the study advocates for institutional support for the IPFs and the incorporation of indigenous poultry in the curriculum of the agricultural training programs at higher education institutions in South Africa.
- Full Text:
- Date Issued: 2014
- Authors: Yusuf, Shehu Folaranmi Gbolahan Shehu
- Date: 2014
- Subjects: Poultry -- Breeding -- South Africa -- Eastern Cape , Chickens -- Breeding -- South Africa -- Eastern Cape , Economic development -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Doctoral , PhD (Agricultural Economics)
- Identifier: vital:11223 , http://hdl.handle.net/10353/d1019833 , Poultry -- Breeding -- South Africa -- Eastern Cape , Chickens -- Breeding -- South Africa -- Eastern Cape , Economic development -- South Africa -- Eastern Cape
- Description: Poverty remains a critical issue mostly in the rural South Africa. Various initiatives, policies and programs have been enacted by the government with attempting to reduce poverty at the national and provincial levels; poverty is yet to be abated. The target of the Millennium Development Goal 1 (MDG1) of halving poverty by the year 2015 notwithstanding, poverty remains a threat to quality livelihoods. Agriculture has continued to be one of the pillars of government efforts to address poverty. However, in livestock production interventions, efforts of government had largely been on cattle, sheep, goats, pigs and exotic poultry with little attention being given to indigenous poultry production (IPP). This study explores the option of using IPP to address rural poverty by capitalizing on its minimal inputs while recognizing its prevalence in a variety of households. The study addresses the characterization of the IPP from the perspectives of housing, feeding, healthcare management, breeding and marketing options.Skill competencies of the indigenous poultry farmers (IPFs) and the Agricultural Development Technicians (ADTs) were examined. This study reviewed poultry models in different parts of the world with special attention to Africa. The human resource development program of the department of rural development and agrarian reform was discussed. The study employed the use of multi-methods approach, the quantitative and qualitative research methodologies. Descriptive statistical analysis, frequent count, percentage, means, standard deviation, chisquare, and principal component analysis was used in the quantitative data analysis while the “open social system” was used for the qualitative methodology. Findings revealed that IPFs face some challenges among which are, the poor housing that exposed the birds to inclement weather, predator attacks and stock theft, high mortality of chicks after hatching and expensive feed for the flock. The IPFs showed competencies in nine skill items that included ability to identify chicken predators (x=3.92) and high yielding chickens (x=3.79); control of predators(x=3.77); methods of using ethno veterinary drugs to treat chicken diseases and pests (x=3.72), and identify signs of diseases (x=3.69), among others. However, the ADTs did not show any competency in any of the 32 skills items. The principal component analysis with Varimax rotation was performed to ascertain the dimensionality of the measures. Six factors with eigen value of >1, which accounted for 77.317% were extracted, with each factor loading ranging from 0.523 to 0.93. Factor loading after rotation that emerged on the same component was described; as brooding, shelter and care of the chicks; predators and healthcare; hygiene and litter management; feeds and feeding stuff; and record keeping and marketing. The findings on the human resource development revealed that staff meetings were the most common method of capacity development. This was followed by in-service-training, formal study, workshop, and on the job training. The farmers’ field school and study tours were sparingly used. However, respondents were in favor of on-site training, staff meetings, formal study and in-service training. The findings on the appropriate model suggest a theoretical indigenous poultry production model (IPPM) for the Eastern Cape Province (ECP). The “open social system” was used to develop a framework for an indigenous poultry cooperative society (to be known as Abafuyi Benkukhu Zemveli [ABZ]). This was meant to create a binding force for capacity development, a strong economic foundation through equity contributions, creation of marketing channels, and the development of a concept of ‘‘our own'' product in the market. Lastly, the study offers options for a training program that would accommodate the new initiatives, with a strong capacity development training approach. In this context, the study advocates for institutional support for the IPFs and the incorporation of indigenous poultry in the curriculum of the agricultural training programs at higher education institutions in South Africa.
- Full Text:
- Date Issued: 2014
Implementation of integrated quality management systems in selected schools, Cofimvaba education district
- Authors: Yotsi, Melekeli
- Date: 2014
- Subjects: Total quality management in education , Total quality management -- South Africa -- Eastern Cape , Teachers -- Quality -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:8283 , http://hdl.handle.net/10948/d1017551
- Description: This study evaluates the implementation of Integrated Quality Management System (IQMS) policy to improve the quality of teaching and learning at schools in the Cofimvaba Education District. IQMS involves the measurement and evaluation of teacher performance for developmental purposes and to reward the best performers in order to improve teaching. A qualitative research approach was adopted and data was collected using questionnaires distributed and retrieved from schools in order to determine educators’ experience of IQMS implementation. The data were then analysed using constant comparative methods. The findings indicate that most participants agreed with the objectives of the policy and felt that it should be retained to evaluate teacher performance for accountability purposes and improved teaching and learning results. The system has the potential to develop educators if is implemented honesty and as long as educators trust the evaluation processes to identify weaknesses and strengths. A key recommendation is that IQMS should be part of the school management team’s responsibilities, which must report quarterly on implementation.
- Full Text:
- Date Issued: 2014
- Authors: Yotsi, Melekeli
- Date: 2014
- Subjects: Total quality management in education , Total quality management -- South Africa -- Eastern Cape , Teachers -- Quality -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:8283 , http://hdl.handle.net/10948/d1017551
- Description: This study evaluates the implementation of Integrated Quality Management System (IQMS) policy to improve the quality of teaching and learning at schools in the Cofimvaba Education District. IQMS involves the measurement and evaluation of teacher performance for developmental purposes and to reward the best performers in order to improve teaching. A qualitative research approach was adopted and data was collected using questionnaires distributed and retrieved from schools in order to determine educators’ experience of IQMS implementation. The data were then analysed using constant comparative methods. The findings indicate that most participants agreed with the objectives of the policy and felt that it should be retained to evaluate teacher performance for accountability purposes and improved teaching and learning results. The system has the potential to develop educators if is implemented honesty and as long as educators trust the evaluation processes to identify weaknesses and strengths. A key recommendation is that IQMS should be part of the school management team’s responsibilities, which must report quarterly on implementation.
- Full Text:
- Date Issued: 2014
Community service professional nurses' experiences of bullying in state hospitals
- Authors: Yon, Gadieja
- Date: 2014
- Subjects: Public health nurses , Bullying in the workplace , State hospitals
- Language: English
- Type: Thesis , Masters , MCur
- Identifier: vital:10056 , http://hdl.handle.net/10948/d1018622
- Description: It is estimated that 80 percent of nurses experience some type of bullying in the workplace during their working lives, and bullying from colleagues has become a major concern. Bullying involves repeated forms of negative behaviours directed at a victim over time. More specifically, the victim is bullied repeatedly over time, with bullying ranging from mild to more severe forms that often go unreported. Bullying in the workplace may cause low self-esteem, depression and anxiety, physical illness and in some cases, the inability to work. The aim of this research study was to explore and describe community service professional nurses’ experiences of being bullied in state hospitals. The information gathered during the course of the study was used to develop strategies that can prevent the bullying of community service professional nurses in the workplace. The design of the study was qualitative, exploratory, descriptive, and contextual in nature. The population sample included all community service professional nurses in state hospitals in the Nelson Mandela Bay area. The researcher employed purposive sampling to select participants from the population of community service professional nurses employed at state hospitals. She collected data by conducting semi-structured individual interviews to gain in-depth accounts from participants and by making observations, which were captured in field notes. Data collected during the interviews were transcribed verbatim and analysed according to Tesch’s eight steps of analysis. Themes were identified through this process and compared to relevant literature. The researcher used the services of an independent coder to aid in the coding process. Trustworthiness was ensured by following Lincoln and Guba’s model of trustworthiness, which comprises the following concepts: credibility, transferability, dependability, and conformability. The researcher ensured that the study adhered to high ethical standards through the principles of justice, beneficence, non-maleficence, and respect for people.
- Full Text:
- Date Issued: 2014
- Authors: Yon, Gadieja
- Date: 2014
- Subjects: Public health nurses , Bullying in the workplace , State hospitals
- Language: English
- Type: Thesis , Masters , MCur
- Identifier: vital:10056 , http://hdl.handle.net/10948/d1018622
- Description: It is estimated that 80 percent of nurses experience some type of bullying in the workplace during their working lives, and bullying from colleagues has become a major concern. Bullying involves repeated forms of negative behaviours directed at a victim over time. More specifically, the victim is bullied repeatedly over time, with bullying ranging from mild to more severe forms that often go unreported. Bullying in the workplace may cause low self-esteem, depression and anxiety, physical illness and in some cases, the inability to work. The aim of this research study was to explore and describe community service professional nurses’ experiences of being bullied in state hospitals. The information gathered during the course of the study was used to develop strategies that can prevent the bullying of community service professional nurses in the workplace. The design of the study was qualitative, exploratory, descriptive, and contextual in nature. The population sample included all community service professional nurses in state hospitals in the Nelson Mandela Bay area. The researcher employed purposive sampling to select participants from the population of community service professional nurses employed at state hospitals. She collected data by conducting semi-structured individual interviews to gain in-depth accounts from participants and by making observations, which were captured in field notes. Data collected during the interviews were transcribed verbatim and analysed according to Tesch’s eight steps of analysis. Themes were identified through this process and compared to relevant literature. The researcher used the services of an independent coder to aid in the coding process. Trustworthiness was ensured by following Lincoln and Guba’s model of trustworthiness, which comprises the following concepts: credibility, transferability, dependability, and conformability. The researcher ensured that the study adhered to high ethical standards through the principles of justice, beneficence, non-maleficence, and respect for people.
- Full Text:
- Date Issued: 2014
Synthesis, photophysicochemical properties and TD-DFT calculations of tetrakis (2-benzoyl-4-chlorophenoxy) phthalocyanines
- Yilmaz, Yusuf, Mack, John, Sener, M Kasim, Sönmez, Mehmet, Nyokong, Tebello
- Authors: Yilmaz, Yusuf , Mack, John , Sener, M Kasim , Sönmez, Mehmet , Nyokong, Tebello
- Date: 2014
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/241538 , vital:50948 , xlink:href="https://doi.org/10.1142/S1088424614500047"
- Description: The synthesis of metal free, magnesium and zinc tetrakis(2-benzoyl-4-chlorophenoxy) phthalocyanine derivatives (2–4) is described along with their characterization by elemental analysis, IR, UV-visible absorption, and 1H NMR spectroscopy and mass spectrometry. Trends observed in the fluorescence, triplet state, singlet oxygen and photodegradation quantum yields and the triplet state lifetimes are also analyzed. The compounds exhibit high solubility in a wide range of organic solvents and no evidence of aggregation was observed over a wide concentration range. The Zn(II) complex (4) was found to have a very high singlet oxygen quantum yield (ΦΔ = 0.78) in dimethylsulfoxide (DMSO) and a reasonably large triplet state quantum yield (ΦT = 0.82). The photophysical and photochemical properties clearly demonstrate that these compounds could prove useful in singlet oxygen applications such as photodynamic therapy (PDT). DFT and TD-DFT calculations were used to assess the impact of the positional isomerism of the 2-benzoyl-4-chlorophenoxy substituents on the electronic structures and optical spectroscopy.
- Full Text:
- Date Issued: 2014
- Authors: Yilmaz, Yusuf , Mack, John , Sener, M Kasim , Sönmez, Mehmet , Nyokong, Tebello
- Date: 2014
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/241538 , vital:50948 , xlink:href="https://doi.org/10.1142/S1088424614500047"
- Description: The synthesis of metal free, magnesium and zinc tetrakis(2-benzoyl-4-chlorophenoxy) phthalocyanine derivatives (2–4) is described along with their characterization by elemental analysis, IR, UV-visible absorption, and 1H NMR spectroscopy and mass spectrometry. Trends observed in the fluorescence, triplet state, singlet oxygen and photodegradation quantum yields and the triplet state lifetimes are also analyzed. The compounds exhibit high solubility in a wide range of organic solvents and no evidence of aggregation was observed over a wide concentration range. The Zn(II) complex (4) was found to have a very high singlet oxygen quantum yield (ΦΔ = 0.78) in dimethylsulfoxide (DMSO) and a reasonably large triplet state quantum yield (ΦT = 0.82). The photophysical and photochemical properties clearly demonstrate that these compounds could prove useful in singlet oxygen applications such as photodynamic therapy (PDT). DFT and TD-DFT calculations were used to assess the impact of the positional isomerism of the 2-benzoyl-4-chlorophenoxy substituents on the electronic structures and optical spectroscopy.
- Full Text:
- Date Issued: 2014
Photophysicochemical properties and TD-DFT calculations of a novel terminal alkyne substituted metal free phthalocyanine
- Yilmaz, Yusuf, Mack, John, Sönmez, Mehmet, Nyokong, Tebello
- Authors: Yilmaz, Yusuf , Mack, John , Sönmez, Mehmet , Nyokong, Tebello
- Date: 2014
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/241562 , vital:50950 , xlink:href="https://doi.org/10.1142/S1088424613501241"
- Description: The synthesis of a novel free base tetrakis(prop-2-ynyloxy)phthalocyanine (2) is described, along with its characterization by IR, UV-visible absorption, and 1H NMR spectroscopy and mass spectrometry. The compound exhibited good solubility in a wide range of organic solvents and no significant aggregation was observed over a wide concentration range. The values for the singlet oxygen (ΦΔ), photodegradation, fluorescence (ΦF) and triplet state quantum yields and the fluorescence and triplet state lifetimes are reported. A relatively high ΦΔ value of 0.46 was obtained in DMSO. The ability to carry out "click" chemistry at the ligand periphery enhances the potential utility of 2 for use in bioconjugates in photodynamic therapy (PDT). A moderately high ΦF value of 0.18 is observed for emission in the therapeutic window in the near-IR region, which suggests that it may also be possible to determine the level of localization of 2 in tumor cells through bioimaging.
- Full Text:
- Date Issued: 2014
- Authors: Yilmaz, Yusuf , Mack, John , Sönmez, Mehmet , Nyokong, Tebello
- Date: 2014
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/241562 , vital:50950 , xlink:href="https://doi.org/10.1142/S1088424613501241"
- Description: The synthesis of a novel free base tetrakis(prop-2-ynyloxy)phthalocyanine (2) is described, along with its characterization by IR, UV-visible absorption, and 1H NMR spectroscopy and mass spectrometry. The compound exhibited good solubility in a wide range of organic solvents and no significant aggregation was observed over a wide concentration range. The values for the singlet oxygen (ΦΔ), photodegradation, fluorescence (ΦF) and triplet state quantum yields and the fluorescence and triplet state lifetimes are reported. A relatively high ΦΔ value of 0.46 was obtained in DMSO. The ability to carry out "click" chemistry at the ligand periphery enhances the potential utility of 2 for use in bioconjugates in photodynamic therapy (PDT). A moderately high ΦF value of 0.18 is observed for emission in the therapeutic window in the near-IR region, which suggests that it may also be possible to determine the level of localization of 2 in tumor cells through bioimaging.
- Full Text:
- Date Issued: 2014
A model of creative and innovative techniques that will prepare final year students to become entrepreneurs
- Authors: Yiadom, Michael Boakye
- Date: 2014
- Subjects: Technological innovations -- Economic aspects , Entrepreneurship -- Study and teaching
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: http://hdl.handle.net/10948/3812 , vital:20465
- Description: Creativity and innovation are significant for the creation of a knowledge and productive base economy with its associated growth, sustainability and job creation. However it is noticed that students will need to employ the techniques on creativity and innovation in order to prepare themselves sufficiently to become business owners and entrepreneurs in this current global world where government jobs are difficult to come by. Therefore, the primary objective of this study is to determine creative and innovative techniques that will prepare final-year students to become entrepreneurs. A hard copy Word document questionnaire was considered an appropriate measurement method for this study. The targeted population of the study included entrepreneurial experts, business owners, teachers and lecturers of business management/studies in the Sisonke District of Kwazulu Natal Province. Thus, some 100 entrepreneur experts, owners of businesses, teachers and lecturers were identified as part of the sampling frame. A total number of 67 questionnaires were administered out of the 100 targeted– giving a response rate of 67%. The quantitative data were processed using Excel, leading to appropriate descriptive statistical analyses, including frequencies, means, medians and standard deviations. In order to obtain a better understanding of a model that will prepare final year students to become entrepreneurs, problem statements and sub-problems were stated and a t-test was used to establish demographic variables, whilst correlation analysis among skills was conducted regarding the model of creative and innovative techniques. Factor analysis was conducted using the Cronbach’s alpha coefficient which confirms that training in the model will prepare students to become entrepreneurs. The results from the empirical study revealed that a model of creative and innovative techniques will prepare students to become entrepreneurs, with a total of 70% of respondents attesting to it. Based on the relevant literature study and the empirical results, recommendations were made in order to support the training needs of students on creativity and innovation techniques. However, the unavailability of an exhaustive entrepreneurial experts database and small number of further education and training colleges in the Sisonke District, did not allow the research to draw on a larger representative sample. Thus, this limitation has impeded in-depth statistical analysis that would have allowed the research to obtain more accurate findings. Further studies could be investigated from lecturers, business owners and experts whether an introduction of a special curriculum on creativity and innovation in further education and training schools may prepare students to become entrepreneurs.
- Full Text:
- Date Issued: 2014
- Authors: Yiadom, Michael Boakye
- Date: 2014
- Subjects: Technological innovations -- Economic aspects , Entrepreneurship -- Study and teaching
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: http://hdl.handle.net/10948/3812 , vital:20465
- Description: Creativity and innovation are significant for the creation of a knowledge and productive base economy with its associated growth, sustainability and job creation. However it is noticed that students will need to employ the techniques on creativity and innovation in order to prepare themselves sufficiently to become business owners and entrepreneurs in this current global world where government jobs are difficult to come by. Therefore, the primary objective of this study is to determine creative and innovative techniques that will prepare final-year students to become entrepreneurs. A hard copy Word document questionnaire was considered an appropriate measurement method for this study. The targeted population of the study included entrepreneurial experts, business owners, teachers and lecturers of business management/studies in the Sisonke District of Kwazulu Natal Province. Thus, some 100 entrepreneur experts, owners of businesses, teachers and lecturers were identified as part of the sampling frame. A total number of 67 questionnaires were administered out of the 100 targeted– giving a response rate of 67%. The quantitative data were processed using Excel, leading to appropriate descriptive statistical analyses, including frequencies, means, medians and standard deviations. In order to obtain a better understanding of a model that will prepare final year students to become entrepreneurs, problem statements and sub-problems were stated and a t-test was used to establish demographic variables, whilst correlation analysis among skills was conducted regarding the model of creative and innovative techniques. Factor analysis was conducted using the Cronbach’s alpha coefficient which confirms that training in the model will prepare students to become entrepreneurs. The results from the empirical study revealed that a model of creative and innovative techniques will prepare students to become entrepreneurs, with a total of 70% of respondents attesting to it. Based on the relevant literature study and the empirical results, recommendations were made in order to support the training needs of students on creativity and innovation techniques. However, the unavailability of an exhaustive entrepreneurial experts database and small number of further education and training colleges in the Sisonke District, did not allow the research to draw on a larger representative sample. Thus, this limitation has impeded in-depth statistical analysis that would have allowed the research to obtain more accurate findings. Further studies could be investigated from lecturers, business owners and experts whether an introduction of a special curriculum on creativity and innovation in further education and training schools may prepare students to become entrepreneurs.
- Full Text:
- Date Issued: 2014
A critical analysis on underutilization of Ante Natal Care services and identification of legislative implementation challenges. A case study in some health centers of Senqu Health sub-District in the Eastern Cape
- Authors: Yekani-Mati, Nokonwaba
- Date: 2014
- Language: English
- Type: Thesis , Masters , MPA
- Identifier: vital:11713 , http://hdl.handle.net/10353/d1015248
- Description: Attention has recently focus on improved Ante Natal Care (ANC) Service utilization as one the Department of Health’s strategies in, promoting better health, ensuring safe mothers and babies, reducing HIV/Aids infection of unborn babies , their mothers and their partners, reaching out as many people, who are at the child bearing age as possible and reaching out to those people who are legible for ART during pregnancy so as to put them on ARV treatment if necessary and ensuring that the mothers, babies and partners enjoy support during the pregnancy of mothers and to prepare them for delivery . The idea is to ensure, by antenatal preparation, the best possible pregnancy outcome for women and their babies (Guidelines for MATERNITY CARE in South Africa NDOH 2007: 19).The departmental guidelines through ante natal care seek to ensure that the following take place timorously: Screening for pregnancy problems: women are done physical and examination and blood test are done to identify or exclude pregnancy problems. Assessment of pregnancy risks: Any pregnancy risks that whether physical, medical, psychological and psychosocial are identified and the mother is advised on better pregnancy management. Treatment of problems that may arise during the antenatal period: when there are existing problems that need treatment the mother get managed and is treated as according to the identified problem.
- Full Text:
- Date Issued: 2014
- Authors: Yekani-Mati, Nokonwaba
- Date: 2014
- Language: English
- Type: Thesis , Masters , MPA
- Identifier: vital:11713 , http://hdl.handle.net/10353/d1015248
- Description: Attention has recently focus on improved Ante Natal Care (ANC) Service utilization as one the Department of Health’s strategies in, promoting better health, ensuring safe mothers and babies, reducing HIV/Aids infection of unborn babies , their mothers and their partners, reaching out as many people, who are at the child bearing age as possible and reaching out to those people who are legible for ART during pregnancy so as to put them on ARV treatment if necessary and ensuring that the mothers, babies and partners enjoy support during the pregnancy of mothers and to prepare them for delivery . The idea is to ensure, by antenatal preparation, the best possible pregnancy outcome for women and their babies (Guidelines for MATERNITY CARE in South Africa NDOH 2007: 19).The departmental guidelines through ante natal care seek to ensure that the following take place timorously: Screening for pregnancy problems: women are done physical and examination and blood test are done to identify or exclude pregnancy problems. Assessment of pregnancy risks: Any pregnancy risks that whether physical, medical, psychological and psychosocial are identified and the mother is advised on better pregnancy management. Treatment of problems that may arise during the antenatal period: when there are existing problems that need treatment the mother get managed and is treated as according to the identified problem.
- Full Text:
- Date Issued: 2014
Synthesis of silver nanoparticles and their role against a thiazolekinase enzyme from Plasmodium falciparum
- Yao, Jia
- Authors: Yao, Jia
- Date: 2014
- Subjects: Silver , Nanoparticles , Thiazoles , Plasmodium falciparum , Antimalarials , Malaria -- Chemotherapy
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4168 , http://hdl.handle.net/10962/d1020894
- Description: Malaria, a mosquito-borne infectious disease, caused by the protozoan Plasmodium genus, is the greatest health challenges worldwide. The plasmodial vitamin B1 biosynthetic enzyme PfThzK diverges significantly, both structurally and functionally from its counterpart in higher eukaryotes, thereby making it particularly attractive as a biomedical target. In the present study, PfThzK was recombinantly produced as 6×His fusion protein in E. coli BL21, purified using nickel affinity chromatography and size exclusion chromatography resulting in 1.03% yield and specific activity 0.28 U/mg. The enzyme was found to be a monomer with a molecular mass of 34 kDa. Characterization of the PfThzK showed an optimum temperature and pH of 37°C and 7.5 respectively, and it is relatively stable (t₁/₂=2.66 h). Ag nanoparticles were synthesized by NaBH₄/tannic acid, and characterized by UV-vis spectroscopy and transmission electron microscopy. The morphologies of these Ag nanoparticles (in terms of size) synthesized by tannic acid appeared to be more controlled with the size of 7.06±2.41 nm, compared with those synthesized by NaBH₄, with the sized of 12.9±4.21 nm. The purified PfThzK was challenged with Ag NPs synthesized by tannic acid, and the results suggested that they competitively inhibited PfThzK (89 %) at low concentrations (5-10 μM) with a Ki = 6.45 μM.
- Full Text:
- Date Issued: 2014
- Authors: Yao, Jia
- Date: 2014
- Subjects: Silver , Nanoparticles , Thiazoles , Plasmodium falciparum , Antimalarials , Malaria -- Chemotherapy
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4168 , http://hdl.handle.net/10962/d1020894
- Description: Malaria, a mosquito-borne infectious disease, caused by the protozoan Plasmodium genus, is the greatest health challenges worldwide. The plasmodial vitamin B1 biosynthetic enzyme PfThzK diverges significantly, both structurally and functionally from its counterpart in higher eukaryotes, thereby making it particularly attractive as a biomedical target. In the present study, PfThzK was recombinantly produced as 6×His fusion protein in E. coli BL21, purified using nickel affinity chromatography and size exclusion chromatography resulting in 1.03% yield and specific activity 0.28 U/mg. The enzyme was found to be a monomer with a molecular mass of 34 kDa. Characterization of the PfThzK showed an optimum temperature and pH of 37°C and 7.5 respectively, and it is relatively stable (t₁/₂=2.66 h). Ag nanoparticles were synthesized by NaBH₄/tannic acid, and characterized by UV-vis spectroscopy and transmission electron microscopy. The morphologies of these Ag nanoparticles (in terms of size) synthesized by tannic acid appeared to be more controlled with the size of 7.06±2.41 nm, compared with those synthesized by NaBH₄, with the sized of 12.9±4.21 nm. The purified PfThzK was challenged with Ag NPs synthesized by tannic acid, and the results suggested that they competitively inhibited PfThzK (89 %) at low concentrations (5-10 μM) with a Ki = 6.45 μM.
- Full Text:
- Date Issued: 2014
Enhancement of the usability of SOA services for novice users
- Authors: Yalezo, Sabelo
- Date: 2014
- Language: English
- Type: Thesis , Masters , MSc (Computer Science)
- Identifier: http://hdl.handle.net/10353/822 , vital:26500
- Description: Recently, the automation of service integration has provided a significant advantage in delivering services to novice users. This art of integrating various services is known as Service Composition and its main purpose is to simplify the development process for web applications and facilitates reuse of services. It is one of the paradigms that enables services to end-users (i.e.service provisioning) through the outsourcing of web contents and it requires users to share and reuse services in more collaborative ways. Most service composers are effective at enabling integration of web contents, but they do not enable universal access across different groups of users. This is because, the currently existing content aggregators require complex interactions in order to create web applications (e.g., Web Service Business Process Execution Language (WS-BPEL)) as a result not all users are able to use such web tools. This trend demands changes in the web tools that end-users use to gain and share information, hence this research uses Mashups as a service composition technique to allow novice users to integrate publicly available Service Oriented Architecture (SOA) services, where there is a minimal active web application development. Mashups being the platforms that integrate disparate web Application Programming Interfaces (APIs) to create user defined web applications; presents a great opportunity for service provisioning. However, their usability for novice users remains invalidated since Mashup tools are not easy to use they require basic programming skills which makes the process of designing and creating Mashups difficult. This is because Mashup tools access heterogeneous web contents using public web APIs and the process of integrating them become complex since web APIs are tailored by different vendors. Moreover, the design of Mashup editors is unnecessary complex; as a result, users do not know where to start when creating Mashups. This research address the gap between Mashup tools and usability by the designing and implementing a semantically enriched Mashup tool to discover, annotate and compose APIs to improve the utilization of SOA services by novice users. The researchers conducted an analysis of the already existing Mashup tools to identify challenges and weaknesses experienced by novice Mashup users. The findings from the requirement analysis formulated the system usability requirements that informed the design and implementation of the proposed Mashup tool. The proposed architecture addressed three layers: composition, annotation and discovery. The researchers developed a simple Mashup tool referred to as soa-Services Provisioner (SerPro) that allowed novice users to create web application flexibly. Its usability and effectiveness was validated. The proposed Mashup tool enhanced the usability of SOA services, since data analysis and results showed that it was usable to novice users by scoring a System Usability Scale (SUS) score of 72.08. Furthermore, this research discusses the research limitations and future work for further improvements.
- Full Text:
- Date Issued: 2014
- Authors: Yalezo, Sabelo
- Date: 2014
- Language: English
- Type: Thesis , Masters , MSc (Computer Science)
- Identifier: http://hdl.handle.net/10353/822 , vital:26500
- Description: Recently, the automation of service integration has provided a significant advantage in delivering services to novice users. This art of integrating various services is known as Service Composition and its main purpose is to simplify the development process for web applications and facilitates reuse of services. It is one of the paradigms that enables services to end-users (i.e.service provisioning) through the outsourcing of web contents and it requires users to share and reuse services in more collaborative ways. Most service composers are effective at enabling integration of web contents, but they do not enable universal access across different groups of users. This is because, the currently existing content aggregators require complex interactions in order to create web applications (e.g., Web Service Business Process Execution Language (WS-BPEL)) as a result not all users are able to use such web tools. This trend demands changes in the web tools that end-users use to gain and share information, hence this research uses Mashups as a service composition technique to allow novice users to integrate publicly available Service Oriented Architecture (SOA) services, where there is a minimal active web application development. Mashups being the platforms that integrate disparate web Application Programming Interfaces (APIs) to create user defined web applications; presents a great opportunity for service provisioning. However, their usability for novice users remains invalidated since Mashup tools are not easy to use they require basic programming skills which makes the process of designing and creating Mashups difficult. This is because Mashup tools access heterogeneous web contents using public web APIs and the process of integrating them become complex since web APIs are tailored by different vendors. Moreover, the design of Mashup editors is unnecessary complex; as a result, users do not know where to start when creating Mashups. This research address the gap between Mashup tools and usability by the designing and implementing a semantically enriched Mashup tool to discover, annotate and compose APIs to improve the utilization of SOA services by novice users. The researchers conducted an analysis of the already existing Mashup tools to identify challenges and weaknesses experienced by novice Mashup users. The findings from the requirement analysis formulated the system usability requirements that informed the design and implementation of the proposed Mashup tool. The proposed architecture addressed three layers: composition, annotation and discovery. The researchers developed a simple Mashup tool referred to as soa-Services Provisioner (SerPro) that allowed novice users to create web application flexibly. Its usability and effectiveness was validated. The proposed Mashup tool enhanced the usability of SOA services, since data analysis and results showed that it was usable to novice users by scoring a System Usability Scale (SUS) score of 72.08. Furthermore, this research discusses the research limitations and future work for further improvements.
- Full Text:
- Date Issued: 2014