Extracellular Hsp90 and TGFP regulate adhesion, migration and anchorage independent growth in a paired colon cancer cell line model
- Authors: de la Mare, Jo-Anne , Jurgens, Tamarin , Edkins, Adrienne L
- Date: 2017
- Language: English
- Type: article , text
- Identifier: http://hdl.handle.net/10962/59920 , vital:27710 , https://doi.org/10.1186/s12885-017-3190-z
- Description: Tumour metastasis remains the major cause of death in cancer patients and, to date, the mechanism and signalling pathways governing this process are not completely understood. The TGF-ß pathway is the most commonly mutated pathway in cancer, however its role in cancer progression is controversial as it can function as both a promoter and a suppressor of metastasis. Although previous studies have suggested a role for the molecular chaperone Hsp90 in regulating the TGF-ß pathway, the level at which this occurs as well as the consequences in terms of colon cancer metastasis are unknown.
- Full Text:
- Date Issued: 2017
Facile synthesis of glutathione-l-Cysteine co-capped CdTe core shell system
- Authors: Daramola, Olamide A , Siwe-Noundou, Xavier , Krause, Rui W M , Marks, John A
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/195003 , vital:45518 , xlink:href="https://doi.org/10.1166/jnn.2017.13823"
- Description: Semiconductor nanoparticles also known as quantum dots (QDs) have been used in diverse areas of application due to their good optical and photo-physical properties. The synthesis of core–shell QDs have assisted to improve the stability of most nano-particles but the size and long term stability of such materials have been problematic. However, thiol-capped CdTe QDs have been regarded as some of the most widely synthesized nanoparticles due to their unique optical properties. The use of un-stable tellurium source such as NaHTe or highly toxic H2Te gas makes the reaction condition cumbersome. In this study, we prepared some CdTe QDs and core–shell QDs using K2TeO3 as a stable source of tellurium without inert gas protection. This was done using a co-capped bio-compatible coating such as cysteine and glutathione following a modified standard method to produce QDs in the yields of about 60 to 80%. All the synthesized materials were subsequently characterized using various characterization techniques. The systematic optimization of the reaction parameters such as reaction time, pH and mole ratio results with a drastic red shift in wavelength (546–600 nm) by the CdTe core proved that an extra material has been deposited unto the surface of the CdTe core. The 60 days stability test conducted demonstrated that the core–shell nanoparticles were quite stable. Since this reaction was performed under open air conditions and no special ligand or buffer solution was used, it may suitably be applied on an industrial scale.
- Full Text:
- Date Issued: 2017
Facilitators for and barriers to the implementation of National Tuberculosis Management Guidelines
- Authors: Dlwati, Lucretia V , Mavundla, Thandisizwe R , Mbengo, Fungai
- Date: 2017
- Subjects: TB management , National Tuberculosis Management Guidelines , Normalization Process Model
- Language: English
- Type: article , text
- Identifier: http://hdl.handle.net/11260/5569 , vital:44607 , https://doi.org/10.25159/2520-5293/2862
- Description: The South African government developed the National Tuberculosis Management Guidelines (NTBMGs) to provide guidance to professional healthcare workers on the management of people with TB and also those co-infected with HIV. However, little is known about primary healthcare (PHC) nurses perceptions of the implementation of the NTBMGs, despite their critical role in TB management. The purpose of this study was to explore PHC nurses perception of the implementation of the NTBMGs in order to identify factors influencing the implementation of the NTBMGs and to make recommendations to improve the implementation of the NTBMGs. The study was conducted in the Eastern Cape, South Africa. The Normalization Process Model (NPM) was used as a theoretical framework to understand the factors influencing the implementation of the NTBMGs. A qualitative, explorative, descriptive and contextual research design was utilised. Data were collected using individual semi-structured interviews on a purposive sample of PHC nurses working in rural clinics. Data were analysed following a descriptive method of Tesch. The study revealed several facilitators for and barriers to the implementation of the NTBMGs based on the NPM. The facilitators included the PHC nurses satisfaction with the Directly Observed Treatment, Short Course (DOTS) strategy in rendering health services to TB patients, the PHC nurses perception of TB meetings as an appropriate platform for problem-solving, of the NTBMGs to be consistent with TB management, and of job satisfaction in relation to patient improvement. The barriers included poverty, inadequate training, shortage of staff, and a lack of material resources, a proper infection control policy, and space. There is a need for the provision of adequate human, material and infrastructural resources in order to eliminate the barriers to the implementation of the NTBMGs.
- Full Text:
- Date Issued: 2017
Factors influencing the shape of CW-OSL signal obtained by stimulation of very deep traps in carbon-doped aluminium oxide: an experimental study
- Authors: Nyirenda, Angel N , Chithambo, Makaiko L
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/115493 , vital:34149 , https://doi.org/10.1016/j.jlumin.2017.07.016
- Description: The optically stimulated luminescence from carbon-doped aluminium oxide (α-Al2O3:C) displays a peak with time under certain measurement conditions. In this paper, we present factors that influence the peak-like shape of continuous-wave optically stimulated luminescence (CW-OSL) signal. The report is based on the experimental study of OSL signals obtained by stimulation of very deep traps in α-Al2O3:C. Methods exploiting post-irradiation annealing, variable dose and temperature dependent OSL measurements were used in the investigation. It is found that the rising part of the CW-OSL peak is obtained when the rate of retrapping at the most optically active trap (main trap) exceeds the rate of direct radiative recombination following optical release of charges from all optically active traps. This is possible if, during optical stimulation, the primary trap responsible for OSL i.e. the main trap, is substantially unoccupied and the very deep, donor traps are substantially filled up. The rate of charge retrapping itself is deduced to depend on the occupancy of the acceptor traps i.e. shallow, main and secondary traps; concentration of charge carriers in the very deep, donor traps; the post-irradiation annealing temperature and the temperature at which the OSL is measured.
- Full Text: false
- Date Issued: 2017
Features of an annealing-induced thermoluminescence peak in α-Al2O3: C, Mg
- Authors: Kalita, Jitumani M , Chithambo, Makaiko L
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/116013 , vital:34289 , DOI: 10.1016/j.optmat.2017.05.034
- Description: We report the thermoluminescence glow curves of beta irradiated single crystal α-Al2O3:C,Mg after annealing at 700 and 900 °C. A glow curve measured at 1 °C/s from samples irradiated to 1 Gy following annealing at 700 and 900 °C shows a high intensity peak at 163 °C and seven secondary peaks of weaker intensity at 43, 73, 100, 195, 280, 329 and 370 °C. Comparing the position of the peaks in the annealed samples with those in an un-annealed one, it is observed that the peak at 100 °C appears only after annealing at and above 700 °C. Kinetic analysis of this annealing-induced peak was carried out using the initial rise, whole glow peak, peak shape, curve fitting and variable heating rate methods. The order of kinetics of the peak was determined as first order using various methods including the Tm-Tstop technique and the dependence of Tm on irradiation dose. The activation energy of the peak is about 1.01 eV and the frequency factor of the order of 1012 s−1. The peak was found to be affected by thermal quenching in analysis based on change of peak intensity with heating rate. The activation energy of thermal quenching was evaluated as 1.06 ± 0.08 eV. We speculate that the annealing-induced peak is due to formation of a new electron trap after destruction of the F22+(2 Mg) centre when the sample is annealed at 700 °C. The annealing-induced peak fades with storage between irradiation and measurement. It was also concluded that electrons from traps corresponding to secondary peaks get re-trapped at the main electron trap.
- Full Text: false
- Date Issued: 2017
Ferrocenyl and organic novobiocin derivatives: synthesis and their in vitro biological activity
- Authors: Mbaba, Mziyanda , Mabhula, Amanda N , Boel, Natasha , Edkins, Adrienne L , Isaacs, Michelle , Hoppe, Heinrich C , Khanye, Setshaba D
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66189 , vital:28914 , https://doi.org/10.1016/j.jinorgbio.2017.04.014
- Description: publisher version , A focused series of novobiocin derivatives containing a ferrocene unit together with their corresponding organic novobiocin analogues have been synthesized in modest to good yields. These compounds were screened for biological activity against a chloroquine-sensitive strain of Plasmodium falciparum (3D7) and human breast cancer cell line (HCC38). With the exception of compounds 5c and 5d, the general trend observed is that incorporation of the ferrocene moiety into novobiocin scaffold resulted in compounds 6a–d/6f showing enhanced activity compared to organic analogues 5a–b and 5e–f.
- Full Text: false
- Date Issued: 2017
Fibronectin is a stress responsive gene regulated by HSF1 in response to geldanamycin
- Authors: Dhanani, Karim C H , Samson, William J , Edkins, Adrienne L
- Date: 2017
- Language: English
- Type: article , text
- Identifier: http://hdl.handle.net/10962/59931 , vital:27711 , https://doi:10.1038/s41598-017-18061-y
- Description: Fibronectin is an extracellular matrix glycoprotein with key roles in cell adhesion and migration. Hsp90 binds directly to fibronectin and Hsp90 depletion regulates fibronectin matrix stability. Where inhibition of Hsp90 with a C-terminal inhibitor, novobiocin, reduced the fibronectin matrix, treatment with an N-terminal inhibitor, geldanamycin, increased fibronectin levels. Geldanamycin treatment induced a stress response and a strong dose and time dependent increase in fibronectin mRNA via activation of the fibronectin promoter. Three putative heat shock elements (HSEs) were identified in the fibronectin promoter. Loss of two of these HSEs reduced both basal and geldanamycin-induced promoter activity, as did inhibition of the stress-responsive transcription factor HSF1. Binding of HSF1 to one of the putative HSE was confirmed by ChIP under basal conditions, and occupancy shown to increase with geldanamycin treatment. These data support the hypothesis that fibronectin is stress-responsive and a functional HSF1 target gene. COLA42 and LAMB3 mRNA levels were also increased with geldanamycin indicating that regulation of extracellular matrix (ECM) genes by HSF1 may be a wider phenomenon. Taken together, these data have implications for our understanding of ECM dynamics in stress-related diseases in which HSF1 is activated, and where the clinical application of N-terminal Hsp90 inhibitors is intended.
- Full Text:
- Date Issued: 2017
Figuring maternity: Christine Dixie's Parturient Prospects
- Authors: Schmahmann, Brenda
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/147748 , vital:38667 , https://doi.org/10.1080/00043389.2007.11877068
- Description: The Interior, Birthing Tray and Parturition are three sub-sections of a project entitled Parturient Prospects that artist Christine Dixie began in 2005, when she was pregnant with her second child, and completed by the end of 2006. In Parturient Prospects, the author reveals, Dixie situates her experiences against Western discourses, especially images from early modern Europe. Focusing on the ways in which visual representations construct woman as ‘other’, Dixie invokes reference to not only representations of birth and maternity but also religious, medical and geographical images.
- Full Text:
- Date Issued: 2017
First example of nonlinear optical materials based on nanoconjugates of sandwich phthalocyanines with quantum dots
- Authors: Oluwole, David O , Yagodin, Alexey V , Mkhize, Nhlakanipho C , Sekhosana, Kutloana E , Martynov, Alexander G , Gorbunova, Yulia G , Tsivadze, Aslan Yu , Nyokong, Tebello
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/238014 , vital:50577 , xlink:href="https://doi.org/10.1002/chem.201604401"
- Description: We report original, selective, and efficient approaches to novel nonlinear optical (NLO) materials, namely homoleptic double- and triple-decker europium(III) complexes 2 and 3 with the A3B-type phthalocyanine ligand (2,3-bis[2′-(2′′-hydroxyethoxy)ethoxy]-9,10,16,17,23,24-hexa-n-butoxyphthalocyanine 1) bearing two anchoring diethyleneglycol chains terminated with OH groups. Their covalently linked nanoconjugates with mercaptosuccinic acid-capped ternary CdSeTe/CdTeS/ZnSeS quantum dots are prepared in the presence of an ethyl(dimethylaminopropyl)carbodiimide activating agent. Optical limiting (OL) properties of the obtained low-symmetry complexes and their conjugates with quantum dots (QDs) are measured for the first time by the open-aperture Z-scan technique (532 nm laser and pulse rate of 10 ns). For comparison, symmetrical double- and triple-decker EuIII octa-n-butoxyphthalocyaninates 5 and 6 and their mixtures with trioctylphosphine oxide-capped QDs are also synthesized and studied. It is revealed that both lowering of molecular symmetry and expansion of the π-electron system upon moving from double- to triple-decker complexes significantly improves the OL characteristics, making the low-symmetry triple-decker complex 3 the most efficient optical limiter in the studied family of sandwich complexes, affording 50 % lowering of light transmittance below 0.5 J cm−2 input fluence. Conjugation (both covalent and noncovalent) with QDs affords further enhancement of the OL properties of both double- and triple-decker complexes. Altogether, the obtained results contribute to the development of novel nonlinear optical materials for future nanoelectronic and optical device applications.
- Full Text:
- Date Issued: 2017
Flexible Metal–Porphyrin Dimers (M= MnIIICl, CoII, NiII, CuII)
- Authors: Li, Minzhi , Zhang, Qian , Xu, Li , Zhu, Weihua , Mack, John , May, Aviwe K , Nyokong, Tebello , Kobayashi, Nagao , Liang, Xu
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/239676 , vital:50754 , xlink:href="https://doi.org/10.1002/cplu.201600475"
- Description: Four metalloporphyrin dimers linked by bridging amide-bonded xanthene moieties and that contain either MnIII, CoII, NiII, or CuII metal centers were synthesized. Various spectroscopic, electrochemical, and spectroelectrochemical methods were used to study trends in their properties. Their electronic structure and optical properties were analyzed through a comparison of the electronic absorption and magnetic circular dichroism (MCD) spectral data with the results of time-dependent (TD)-DFT calculations.
- Full Text:
- Date Issued: 2017
Fluorescence behaviour of supramolecular hybrids containing graphene quantum dots and pyrene-derivatized phthalocyanines and porphyrins
- Authors: Achadu, Ojodomo John , Managa, Muthumuni , Nyokong, Tebello
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/188953 , vital:44801 , xlink:href="https://doi.org/10.1016/j.jphotochem.2016.10.029"
- Description: Novel pyrene-derivatized zinc and cobalt phthalocyanines (Pcs) and porphyrins (Ps) were immobilized on graphene quantum dots (GQDs) to form GQDs-Pcs and GQDs-Ps supramolecular hybrids via the π–π stacking interaction method. Spectroscopic evidence shows that the resultant hybrids were stable owing to the strong π–π stacking interaction between the GQDs and the respective Pcs and Ps, thus leading to the fabrication of interesting and functional supramolecular hybrids by taking advantage of the delocalized π electron systems of GQDs and the macrocycles. The conjugates showed increased fluorescence quantum yields for the Pcs/Ps, but decreased values for the GQDs in the conjugates. These novel hybrid materials could potentially be deployed for studies in both fundamental and applied perspectives due to the synergistic contributions resulting from the combination of their excellent electronic and optical properties.
- Full Text:
- Date Issued: 2017
Forensic entomotoxicology revisited: towards professional standardisation of study designs
- Authors: da Silva, Erica I T , Wilhelmi, Brendan S , Villet, Martin H
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/140819 , vital:37921 , DOI: 10.1007/s00414-017-1603-9
- Description: Forensic entomotoxicology is the use of insects as evidence of whether a toxicant is present in an environment such as a corpse, river or landscape. The earliest overtly forensic study was published in 1977, and since then, at least 63 papers have been published, most of them focused on the detection of toxicants in insects or on effects of toxicants on diverse insect indicator taxa. A comprehensive review of the published literature revealed various inconsistencies between studies that could be addressed by introducing standard protocols for such studies. These protocols could include selecting widespread and common model organisms (such as Lucilia sericata, Calliphora vicina, Chrysomya megacephala and Dermestes maculatus) and model toxicants (e.g. morphine and amitriptyline) to build up comparative databases; developing a standard matrix for use as a feeding substrate; setting guidelines for statistically adequate sample sizes; and deploying more sophisticated analytical methods from the general field of toxicology.
- Full Text:
- Date Issued: 2017
Forest degradation and invasive species synergistically impact Mimusops andongensis (Sapotaceae) in Lama Forest Reserve, Benin
- Authors: Sinasson, Gisèle K , Shackleton, Charlie M , Glèlè Kakaï, Romain L , Sinsin, Brice
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/182038 , vital:43792 , xlink:href="https://doi.org/10.1111/btp.12370"
- Description: Harvesting of Non-Timber Forest Products (NTFPs) can threaten target species, especially those with limited distribution and density. Exploited species also face threats from habitat fragmentation, fire, and invasive species. We assessed the impact of human disturbances and invasive species on the population of a key multipurpose NTFP species, Mimusops andongensis, in Lama Forest reserve (Benin). The densities of adult trees and regenerative stems decreased with increasing degradation. Mimusops andongensis contributed less to total tree density with increasing human disturbance. There were significantly fewer M. andongensis recruits with increasing cover of invasive Chromolaena odorata. Smaller diameter individuals predominated in non-degraded and moderately degraded sites while in degraded sites, the structure showed a negative exponential trend with the density of small diameter individuals being less than two trees/ha. Larger individuals were also rare in degraded sites. The low density of both mature trees and seedlings in degraded sites may undermine the long-term viability of M. andongensis, despite existing protection against NTFP harvesting and other anthropogenic pressures. Management should emphasize facilitating recruitment subsidies and limiting the presence of C. odorata.
- Full Text:
- Date Issued: 2017
Framing of transitional pedagogic practices in the sciences: enabling access
- Authors: Ellery, Karen
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66381 , vital:28942 , https://doi.org/10.1080/13562517.2017.1319812
- Description: publisher version , Educational literature shows that students from working-class backgrounds are significantly less likely to persist to completion in higher education than middle-class students. This paper draws theoretically and analytically on Bernstein’s ([1990. Class, Codes and Control, Volume IV: The Structuring of Pedagogic Discourse. London: Routledge; 2000. Pedagogy, Symbolic Control, and Identity: Theory, Research, Critique. Lanham: Rowman and Littlefield]) thesis that, through differential framing of pedagogic practices, the curriculum has capacity to accommodate all groups of students. Pedagogic practices in both a science foundation course and four first-year mainstream science courses in a higher education institution in the South African context are examined. Whilst the foundation course exhibits modalities that generally favour access, the mainstream courses have some modalities that appear to be constraining. It is argued from a social justice perspective that holistic curriculum transformations that better enable epistemic transitions are an urgent imperative, and that consideration of differential framing of pedagogic modalities offer a close-up empirical means of conceptualising such reforms.
- Full Text: false
- Date Issued: 2017
From Baudelaire to Beardsley: some thoughts on Poe's beast as an indicator of the tastes and fears of nineteenth-century Europe
- Authors: Beard, Margot
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/147781 , vital:38672 , https://doi.org/10.1080/00043389.2001.11876980
- Description: Charles Baudelaire (1821 1867) was one of the major influences on the French Decadent poets of the late nineteenth century whose aesthetic principles were shared, to a large extent, by a group of English poets and artists, among whom was Aubrey Beardsley (1872 1898). One of the major influences on Baude laire had been the American, Edgar Allan Poe (1809 1849), in whose short stories and poems Baudelaire had recognised a kindred spirit. Some intriguing aspects of changing nine teenth century attitudes emerge from a study of Baudelaire's 1856 translation of Poe's `The Murders in the Rue Morgue' and Beardsley's 1893 illustration to this story.
- Full Text:
- Date Issued: 2017
From contradictions to complementarities: a social realist analysis of the evolution of academic development within a department
- Authors: Case, Jennifer M , Heydenrych, Hilton , Kotta, Linda , Marshall, Delia , McKenna, Sioux , Willliams, Kevin
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66752 , vital:28990 , ISSN 1470-1294 , https://doi.org/10.1080/03075079.2015.1045479
- Description: Publisher version , Academic development is a recent project in the university, intended to enable the university to respond to the needs of a more diverse student body. In South Africa, such work arose during late apartheid, and has now moved to a more central institutional position advocating responsiveness in the light of the educational disparities that are the legacy of apartheid. The present study uses a social realist perspective to analyse the 25-year evolution of an academic development project within an engineering department at a South African university. The findings show that while academic development initially posed a contradictory logic to the department, the response was to reform the nature of this project into one that suited the other commitments of the department: a logic of complementarity. The department's relationships with industry were shown to have played a key role in fostering this form of change.
- Full Text: false
- Date Issued: 2017
From Technauriture to Cultauriture: Developing a Coherent Digitisation Paradigm for Enhancing Cultural Impact
- Authors: Mostert, André M , Lisney, Bob , Maroko, Geoffrey M , Kaschula, Russell H
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/124528 , vital:35625 , http://www.ijscl.net/article_26650.html
- Description: Developing suitable frameworks and paradigms (theoretical and practical) is a challenge for all disciplines in the face of rapid technological changes. Technological advances are fundamentally changing discourse in many well-established areas of research; from advances in understanding the brain, questioning the informed wisdom of sectors of the brain, through to impacts of social networks on sociology, to digitisation of culture. Technology’s potential is a double-edged sword which calls for coherent and reflective practices, to avoid the many pitfalls which abound. Kaschula recognised this as far back as 2004 in terms of orality, oral societies, and developed Technauriture as a framing solution. Drawing from this experience, the authors aim to expand the concept to offer a framing paradigm for culture in the form of Cultauriture. In this article the concept of Cultauriture is introduced and expanded to create a base for further research and dialogue with and between cultural practitioners, artists and policy makers.
- Full Text:
- Date Issued: 2017
Fuelwood preferences, use and availability in the #Khomani San resettlement farms, southern Kalahari, South Africa
- Authors: Nott, Michelle , Thondhlana, Gladman
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/67667 , vital:29127 , https://doi.org/10.1080/14728028.2017.1294507
- Description: Publisher version , Local level assessments of fuelwood preferences, demand and supply are important for ensuring a balance between ecological functions and livelihood needs. This study reports on an examination of fuelwood preferences, use and abundance in the #Khomani San resettlement farms in southern Kalahari, South Africa. The results show that Acacia erioloba was the most preferred fuelwood species, while Acacia mellifera was abundant but avoided. Across the study area, there were approximately 64 trees ha−1 but riverine sites had significantly more trees (approximately 80 trees ha−1) than non-riverine sites (48 trees ha−1). Live trees showed evidence of damage (cutting or breaking) and this was more pronounced in the riverine sites (close to human settlement) than in the non-riverine sites. However, overall current woody stocks and productivity rates of harvestable fuelwood are well above current fuelwood demand, suggesting fuelwood use may be within sustainable limits, though there is evidence of localised fuelwood depletion. The implications of these results for fuelwood management interventions, including the importance of context, are discussed.
- Full Text: false
- Date Issued: 2017
Gender, dialogue and discursive psychology: A pilot sexuality intervention with South African high-school learners
- Authors: Jearey-Graham, Nicola , Macleod, Catriona I
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/444326 , vital:74219 , xlink:href="https://doi.org/10.1080/14681811.2017.1320983"
- Description: Good-quality sexuality education can be effective in reducing sexual health risks, but may also be disconnected from the lived realities of learners’ lives and reinforce gendered stereotypes. In line with the trend towards ‘empowerment’ in and through sexuality education, we implemented a pilot sexuality intervention with Grade 10 participants following a rigorous consultation process. Nine weekly group dialogues were held with 11 participants, with 2 follow-up sessions the next year. Freirian principles of critical consciousness and dialogical pedagogy, infused with discursive psychological understandings, were used to foreground gendered/sexual norms and to provide recognition for participants in a variety of gendered and sexual subject positions. Sessions were recorded, the facilitator kept a diary, and participants were asked to evaluate the intervention. The dialogical format of the group generated curiosity and engagement, and some participants took up a ‘responsible’ sexual subject position in a reflexive manner. A partial normalisation of some ‘hidden’ aspects of sex was enabled, and critical consciousness around some gendered inequities was promoted. We argue, first, that it is not so much sexuality education that young people need, but sexuality dialogues, and second, that a discursive psychology framework provides a nuanced and fruitful dimension to Freirean inspired ‘empowerment’ sexuality interventions.
- Full Text:
- Date Issued: 2017
Generic gold standard or contextualised public good? Teaching excellence awards in post-colonial South Africa
- Authors: Behari-Leak, Kasturi , McKenna, Sioux
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66774 , vital:28992 , ISSN 1470-1294 , https://doi.org/10.1080/13562517.2017.1301910
- Description: Publisher version , Teaching Excellence Awards have raised the profile of teaching as a scholarly project. There are however a number of questions about what constitutes teaching excellence and how ‘excellence’ is understood in current higher education. In a post-colonial South Africa, where significant injustices permeate our society, we question whether excellence can be understood in a generic manner. Furthermore, we argue that as universities are a public good, teaching excellence needs to explicitly attend to the ways in which universities contribute to broad goals of transformation and inclusivity. We analysed data from the national Teaching Excellence Awards and 13 South African universities’ awards to interrogate the discourses that underpin ‘excellence’ in this context of social inequality. We found that while the awards have gone some way to enhancing the position of teaching in institutions, ‘excellence’ was largely articulated in fairly generic ways which failed to take into account the enablements and constraints of the discipline and the institution. Furthermore, the guidelines and criteria privilege a decontextualised notion of excellence that seeks a ‘gold standard’ and validates performativity, rather than a contextualised response to the needs of the students.
- Full Text: false
- Date Issued: 2017