Erasure: A challenge to Feminist and Queer research
- Marx, Jacqueline, Macleod, Catriona I
- Authors: Marx, Jacqueline , Macleod, Catriona I
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , book chapter
- Identifier: http://hdl.handle.net/10962/434210 , vital:73039 , ISBN 978-3-319-74720-0 , https://link.springer.com/chapter/10.1007/978-3-319-74721-7_20
- Description: Anonymity and confidentiality feature prominently in research ethics guidelines. In this chapter we draw on examples from a research ethics application for a project involving women who had extricated themselves from relationships in which they had experienced intimate partner violence, and an ethnographic study of cross-dressing and drag, to illustrate the multiple ways in which identity masking can be put to work, both promoting and undermining what it means to do ethical research. We argue that the requirement for anonymity and confidentiality cannot be assessed without taking into account historicity and the sociopolitical contexts in which a study and its participants are located. The chapter concludes by giving consideration to the potential of a situated ethics approach and the implications for ethics review processes.
- Full Text:
- Date Issued: 2018
- Authors: Marx, Jacqueline , Macleod, Catriona I
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , book chapter
- Identifier: http://hdl.handle.net/10962/434210 , vital:73039 , ISBN 978-3-319-74720-0 , https://link.springer.com/chapter/10.1007/978-3-319-74721-7_20
- Description: Anonymity and confidentiality feature prominently in research ethics guidelines. In this chapter we draw on examples from a research ethics application for a project involving women who had extricated themselves from relationships in which they had experienced intimate partner violence, and an ethnographic study of cross-dressing and drag, to illustrate the multiple ways in which identity masking can be put to work, both promoting and undermining what it means to do ethical research. We argue that the requirement for anonymity and confidentiality cannot be assessed without taking into account historicity and the sociopolitical contexts in which a study and its participants are located. The chapter concludes by giving consideration to the potential of a situated ethics approach and the implications for ethics review processes.
- Full Text:
- Date Issued: 2018
Ethics in critical research: Stories from the field
- Macleod, Catriona I, Marx, Jacqueline, Mnyaka, Phindezwa, Treharne, Gareth J
- Authors: Macleod, Catriona I , Marx, Jacqueline , Mnyaka, Phindezwa , Treharne, Gareth J
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , book chapter
- Identifier: http://hdl.handle.net/10962/434223 , vital:73040 , ISBN 978-3-319-74720-0 , https://link.springer.com/chapter/10.1007/978-3-319-74721-7_1
- Description: In this chapter we introduce the approaches to ethics in critical research applied throughout this handbook. Critical research questions who benefits from research and offers critiques rooted in postmodern and liberatory theories, including feminism, Marxism, and postcolonialism. Authors of chapters in the handbook explore ethical issues faced when conducting critical research through stories from the field across a range of methodologies, disciplines, and locations. The chapter overviews the four sections of the handbook and the ethical challenges associated with conducting critical research within the bureaucracy of ethics committees and other systems of governance, blurring the boundaries between researchers and participants/co-researchers, giving voice through research whilst applying anonymity or naming participants/co-researchers, and conducting research with various configurations of power between researchers and participants/co-researchers.
- Full Text:
- Date Issued: 2018
- Authors: Macleod, Catriona I , Marx, Jacqueline , Mnyaka, Phindezwa , Treharne, Gareth J
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , book chapter
- Identifier: http://hdl.handle.net/10962/434223 , vital:73040 , ISBN 978-3-319-74720-0 , https://link.springer.com/chapter/10.1007/978-3-319-74721-7_1
- Description: In this chapter we introduce the approaches to ethics in critical research applied throughout this handbook. Critical research questions who benefits from research and offers critiques rooted in postmodern and liberatory theories, including feminism, Marxism, and postcolonialism. Authors of chapters in the handbook explore ethical issues faced when conducting critical research through stories from the field across a range of methodologies, disciplines, and locations. The chapter overviews the four sections of the handbook and the ethical challenges associated with conducting critical research within the bureaucracy of ethics committees and other systems of governance, blurring the boundaries between researchers and participants/co-researchers, giving voice through research whilst applying anonymity or naming participants/co-researchers, and conducting research with various configurations of power between researchers and participants/co-researchers.
- Full Text:
- Date Issued: 2018
Evaluating the efficacy of Hypogeococcus sp. as a biological control agent of the cactaceous weed Cereus jamacaru in South Africa
- Sutton, Guy F, Klein, H, Paterson, Iain D
- Authors: Sutton, Guy F , Klein, H , Paterson, Iain D
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/423350 , vital:72051 , xlink:href="https://doi.org/10.1007/s10526-018-9887-3"
- Description: We evaluated the efficacy of Hypogeococcus sp. (Hemiptera: Pseudococcidae) as a biological control agent of the cactaceous weed Cereus jamacaru De Candolle (Queen of the Night cactus) in South Africa. This weed has been described as being under complete biological control due to the action of Hypogeococcus sp., although no formal post-release evaluation had been conducted prior to this study. Biological control was associated with significant reductions in fruiting, plant survival and plant densities, while plant population age structures were negatively affected. Weed populations infected by Hypogeococcus sp. were typified by low or non-existent recruitment and are expected to diminish with time. Populations where Hypogeococcus sp. was absent displayed extensive recruitment, and are predicted to expand or self-replace, if left unchecked. These data indicate that Hypogeococcus sp. has a significant negative effect on C. jamacaru at the individual plant and population level, and given sufficient time provides complete biological control over this weed in South Africa.
- Full Text:
- Date Issued: 2018
- Authors: Sutton, Guy F , Klein, H , Paterson, Iain D
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/423350 , vital:72051 , xlink:href="https://doi.org/10.1007/s10526-018-9887-3"
- Description: We evaluated the efficacy of Hypogeococcus sp. (Hemiptera: Pseudococcidae) as a biological control agent of the cactaceous weed Cereus jamacaru De Candolle (Queen of the Night cactus) in South Africa. This weed has been described as being under complete biological control due to the action of Hypogeococcus sp., although no formal post-release evaluation had been conducted prior to this study. Biological control was associated with significant reductions in fruiting, plant survival and plant densities, while plant population age structures were negatively affected. Weed populations infected by Hypogeococcus sp. were typified by low or non-existent recruitment and are expected to diminish with time. Populations where Hypogeococcus sp. was absent displayed extensive recruitment, and are predicted to expand or self-replace, if left unchecked. These data indicate that Hypogeococcus sp. has a significant negative effect on C. jamacaru at the individual plant and population level, and given sufficient time provides complete biological control over this weed in South Africa.
- Full Text:
- Date Issued: 2018
Evaluation of the photophysicochemical properties and photodynamic therapy activity of nanoconjugates of zinc phthalocyanine linked to glutathione capped Au and Au3Ag1 nanoparticles
- Oluwole, David O, Manoto, Sello L, Malabi, Rudzani, Maphanga, Charles, Ombinda-Lemboumba, Saturnin, Mthunzi-Kufa, Patience, Nyokong, Tebello
- Authors: Oluwole, David O , Manoto, Sello L , Malabi, Rudzani , Maphanga, Charles , Ombinda-Lemboumba, Saturnin , Mthunzi-Kufa, Patience , Nyokong, Tebello
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/237886 , vital:50563 , xlink:href="https://doi.org/10.1016/j.dyepig.2017.11.019"
- Description: We report on the synthesis of glutathione capped gold (AuNPs–GSH) and gold–silver (Au3Ag1NPs–GSH) nanoparticles and their covalent attachment to Zn monocarboxyphenoxy phthalocyanine (1) via amide bond formation. The photophysicochemical properties and photodynamic therapy (PDT) activity of the complex and its nanoconjugates were assessed. The conjugates afforded improved triplet and singlet oxygen quantum yield as well as PDT activity (except for 1-Au3Ag1NPs which afforded decreased activity) in comparison to complex 1.
- Full Text:
- Date Issued: 2018
- Authors: Oluwole, David O , Manoto, Sello L , Malabi, Rudzani , Maphanga, Charles , Ombinda-Lemboumba, Saturnin , Mthunzi-Kufa, Patience , Nyokong, Tebello
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/237886 , vital:50563 , xlink:href="https://doi.org/10.1016/j.dyepig.2017.11.019"
- Description: We report on the synthesis of glutathione capped gold (AuNPs–GSH) and gold–silver (Au3Ag1NPs–GSH) nanoparticles and their covalent attachment to Zn monocarboxyphenoxy phthalocyanine (1) via amide bond formation. The photophysicochemical properties and photodynamic therapy (PDT) activity of the complex and its nanoconjugates were assessed. The conjugates afforded improved triplet and singlet oxygen quantum yield as well as PDT activity (except for 1-Au3Ag1NPs which afforded decreased activity) in comparison to complex 1.
- Full Text:
- Date Issued: 2018
Evidence for a new regime shift between floating and submerged invasive plant dominance in South Africa
- Strange, Emily F, Hill, Martin P, Coetzee, Julie A
- Authors: Strange, Emily F , Hill, Martin P , Coetzee, Julie A
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/423993 , vital:72114 , xlink:href="https://doi.org/10.1007/s10750-018-3506-2"
- Description: Classical biological control for the management of floating invasive plants has been highly successful in South Africa. However, restoring ecosystem services has been compromised by a new suite of submerged invasive plants. This study proposes that biological control of floating invasive macrophytes acts as a catalyst in a regime shift between floating and submerged invasive plant dominance. Regime shifts are large and sudden changes in the structure and functioning of ecosystems. The proposed shift is driven by the rapid decomposition of floating plants and subsequent increase in availability of nutrients and light. A mesocosm experiment explored the effect of biological control on floating Pistia stratiotes L. (Araceae) upon the growth of invasive submerged Egeria densa Planch. (Hydrocharitaceae), and native submerged plant species of the same family; Lagarosiphon major (Ridl.) Moss (Hydrocharitaceae). The results revealed a cascade effect of biological control of P. stratiotes on the availability of nitrogen, resulting in increased relative growth rates and invasive capacity for E. densa. In contrast, the native L. major could not compete with healthy or damaged P. stratiotes. These findings highlight the vulnerability of South African freshwater systems to submerged plant invasions and demonstrate the importance of a more holistic approach to invasive plant management.
- Full Text:
- Date Issued: 2018
- Authors: Strange, Emily F , Hill, Martin P , Coetzee, Julie A
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/423993 , vital:72114 , xlink:href="https://doi.org/10.1007/s10750-018-3506-2"
- Description: Classical biological control for the management of floating invasive plants has been highly successful in South Africa. However, restoring ecosystem services has been compromised by a new suite of submerged invasive plants. This study proposes that biological control of floating invasive macrophytes acts as a catalyst in a regime shift between floating and submerged invasive plant dominance. Regime shifts are large and sudden changes in the structure and functioning of ecosystems. The proposed shift is driven by the rapid decomposition of floating plants and subsequent increase in availability of nutrients and light. A mesocosm experiment explored the effect of biological control on floating Pistia stratiotes L. (Araceae) upon the growth of invasive submerged Egeria densa Planch. (Hydrocharitaceae), and native submerged plant species of the same family; Lagarosiphon major (Ridl.) Moss (Hydrocharitaceae). The results revealed a cascade effect of biological control of P. stratiotes on the availability of nitrogen, resulting in increased relative growth rates and invasive capacity for E. densa. In contrast, the native L. major could not compete with healthy or damaged P. stratiotes. These findings highlight the vulnerability of South African freshwater systems to submerged plant invasions and demonstrate the importance of a more holistic approach to invasive plant management.
- Full Text:
- Date Issued: 2018
Exploration and design of a synchronous message passing framework for a CPU-NPU heterogeneous architecture
- Pennefather, Sean, Bradshaw, Karen L, Irwin, Barry V W
- Authors: Pennefather, Sean , Bradshaw, Karen L , Irwin, Barry V W
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/429537 , vital:72620 , https://ieeexplore.ieee.org/abstract/document/8425384
- Description: In this paper we present the development of a framework for communication between an NPU (network processing unit) and CPU through synchronous message passing that is compliant with the synchronous communication events of the CSP formalisms. This framework is designed to be used for passing generic information between application components operating on both architectures and is intended to operate in conjunction with existing datapaths present on the NPU which in turn are responsible for network traffic transmission. An investigation of different message passing topologies is covered before the proposed message passing fabric is presented. As a proof of concept, an initial implementation of the fabric is developed and tested to determine its viability and correctness. Through testing it is shown that the implemented framework operates as intended. However, it is noted the throughput of the exploratory implementation is not considered suitable for high-performance applications and further evaluation is required.
- Full Text:
- Date Issued: 2018
- Authors: Pennefather, Sean , Bradshaw, Karen L , Irwin, Barry V W
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/429537 , vital:72620 , https://ieeexplore.ieee.org/abstract/document/8425384
- Description: In this paper we present the development of a framework for communication between an NPU (network processing unit) and CPU through synchronous message passing that is compliant with the synchronous communication events of the CSP formalisms. This framework is designed to be used for passing generic information between application components operating on both architectures and is intended to operate in conjunction with existing datapaths present on the NPU which in turn are responsible for network traffic transmission. An investigation of different message passing topologies is covered before the proposed message passing fabric is presented. As a proof of concept, an initial implementation of the fabric is developed and tested to determine its viability and correctness. Through testing it is shown that the implemented framework operates as intended. However, it is noted the throughput of the exploratory implementation is not considered suitable for high-performance applications and further evaluation is required.
- Full Text:
- Date Issued: 2018
Exploring learning networks for homestead food gardening and smallholder farming
- Authors: Lotz-Sisitka, Heila
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/182775 , vital:43873 , xlink:href="https://hdl.handle.net/10520/EJC-f09c3866c "
- Description: The Water Research Commission (WRC) is well known for its high quality knowledge products. The Water Utilisation in Agriculture (WUA) section has, over the years, produced valuable knowledge to guide the harvesting and conservation of rainwater to improve agricultural productivity among smallholder crop farmers and household food producers. This knowledge is useful for especially the many women farmers around the country growing crops to feed their families, and whenever possible selling excess to generate some income. However, one of the problems experienced in the field is that this knowledge does not always reach the intended audience. This is the problem that the Amanzi [Water] for Food project was engaged with.
- Full Text:
- Date Issued: 2018
- Authors: Lotz-Sisitka, Heila
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/182775 , vital:43873 , xlink:href="https://hdl.handle.net/10520/EJC-f09c3866c "
- Description: The Water Research Commission (WRC) is well known for its high quality knowledge products. The Water Utilisation in Agriculture (WUA) section has, over the years, produced valuable knowledge to guide the harvesting and conservation of rainwater to improve agricultural productivity among smallholder crop farmers and household food producers. This knowledge is useful for especially the many women farmers around the country growing crops to feed their families, and whenever possible selling excess to generate some income. However, one of the problems experienced in the field is that this knowledge does not always reach the intended audience. This is the problem that the Amanzi [Water] for Food project was engaged with.
- Full Text:
- Date Issued: 2018
Exploring the potential of developmental work research and change laboratory to support sustainability transformations: a case study of organic agriculture in Zimbabwe
- Mukute, Mutizwa, Mudokwani, Kuda, McAllistair, Georgina, Nyikahadzoi, Kefasi
- Authors: Mukute, Mutizwa , Mudokwani, Kuda , McAllistair, Georgina , Nyikahadzoi, Kefasi
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/392119 , vital:68723 , xlink:href="https://doi.org/10.1080/10749039.2018.1451542"
- Description: This paper explores the emergence of transgressive learning in CHAT-informed development work research in a networked organic agriculture case study in Zimbabwe, based on intervention research involving district organic associations tackling interconnected issues of climate change, water, food security and solidarity. The study established that We change laboratories can be used to support transgressive learning through: confronting unproductive local norms; collective reframing of problematic issues; stimulating expansive learning and sustainability transformations in minds, relationships and landscapes across time. The study also confirms the need for fourth generation CHAT to address the complex social-ecological problems of today.
- Full Text:
- Date Issued: 2018
- Authors: Mukute, Mutizwa , Mudokwani, Kuda , McAllistair, Georgina , Nyikahadzoi, Kefasi
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/392119 , vital:68723 , xlink:href="https://doi.org/10.1080/10749039.2018.1451542"
- Description: This paper explores the emergence of transgressive learning in CHAT-informed development work research in a networked organic agriculture case study in Zimbabwe, based on intervention research involving district organic associations tackling interconnected issues of climate change, water, food security and solidarity. The study established that We change laboratories can be used to support transgressive learning through: confronting unproductive local norms; collective reframing of problematic issues; stimulating expansive learning and sustainability transformations in minds, relationships and landscapes across time. The study also confirms the need for fourth generation CHAT to address the complex social-ecological problems of today.
- Full Text:
- Date Issued: 2018
Extending the NFComms framework for bulk data transfers
- Pennefather, Sean, Bradshaw, Karen L, Irwin, Barry V W
- Authors: Pennefather, Sean , Bradshaw, Karen L , Irwin, Barry V W
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/430152 , vital:72669 , https://doi.org/10.1145/3278681.3278686
- Description: In this paper we present the design and implementation of an indirect messaging extension for the existing NFComms framework that pro-vides communication between a network flow processor and host CPU. This extension addresses the bulk throughput limitations of the frame-work and is intended to work in conjunction with existing communication mediums. Testing of the framework extensions shows an increase in throughput performance of up to 300× that of the current direct mes-sage passing framework at the cost of increased single message laten-cy of up to 2×. This trade-off is considered acceptable as the proposed extensions are intended for bulk data transfer only while the existing message passing functionality of the framework is preserved and can be used in situations where low latency is required for small messages.
- Full Text:
- Date Issued: 2018
- Authors: Pennefather, Sean , Bradshaw, Karen L , Irwin, Barry V W
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/430152 , vital:72669 , https://doi.org/10.1145/3278681.3278686
- Description: In this paper we present the design and implementation of an indirect messaging extension for the existing NFComms framework that pro-vides communication between a network flow processor and host CPU. This extension addresses the bulk throughput limitations of the frame-work and is intended to work in conjunction with existing communication mediums. Testing of the framework extensions shows an increase in throughput performance of up to 300× that of the current direct mes-sage passing framework at the cost of increased single message laten-cy of up to 2×. This trade-off is considered acceptable as the proposed extensions are intended for bulk data transfer only while the existing message passing functionality of the framework is preserved and can be used in situations where low latency is required for small messages.
- Full Text:
- Date Issued: 2018
Family functioning and socioeconomic status in South African families: A test of the social causation hypothesis
- Botha, Ferdi, Booysen, Frikkie, Wouters, Edwin
- Authors: Botha, Ferdi , Booysen, Frikkie , Wouters, Edwin
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/433176 , vital:72948 , xlink:href="https://doi.org/10.1007/s11205-017-1600-x"
- Description: Optimal family relationships are central to individual well-being. The focus of this paper is on family functioning and how socioeconomic status (SES) explains family functioning. Ecological theory states that a family’s socioeconomic context is determined by macro-systemic factors, thereby influencing individuals’ perceptions of family functioning. Within this context, the social causation hypothesis asserts that social conditions influence family functioning. This paper uses the Family Attachment and Changeability Index as measure of family functioning. SES is viewed as multidimensional and individual-, household-, and subjective SES indices are developed using multiple correspondence analysis. Multivariate regression models suggest that household- and subjective SES are associated with higher levels of perceived flexibility in the family. There is no association between SES and family members’ attachment to each other. In general, the findings support the social causation hypothesis.
- Full Text:
- Date Issued: 2018
- Authors: Botha, Ferdi , Booysen, Frikkie , Wouters, Edwin
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/433176 , vital:72948 , xlink:href="https://doi.org/10.1007/s11205-017-1600-x"
- Description: Optimal family relationships are central to individual well-being. The focus of this paper is on family functioning and how socioeconomic status (SES) explains family functioning. Ecological theory states that a family’s socioeconomic context is determined by macro-systemic factors, thereby influencing individuals’ perceptions of family functioning. Within this context, the social causation hypothesis asserts that social conditions influence family functioning. This paper uses the Family Attachment and Changeability Index as measure of family functioning. SES is viewed as multidimensional and individual-, household-, and subjective SES indices are developed using multiple correspondence analysis. Multivariate regression models suggest that household- and subjective SES are associated with higher levels of perceived flexibility in the family. There is no association between SES and family members’ attachment to each other. In general, the findings support the social causation hypothesis.
- Full Text:
- Date Issued: 2018
From deviant choice to feminist issue: An historical analysis of scholarship on voluntary childlessness (1920–2013)
- Lynch, Ingrid, Morison, Tracy, Macleod, Catriona I, Mijas, Magdalena, du Toit, Ryan, Shivakumar, Seemanthini T
- Authors: Lynch, Ingrid , Morison, Tracy , Macleod, Catriona I , Mijas, Magdalena , du Toit, Ryan , Shivakumar, Seemanthini T
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , book chapter
- Identifier: http://hdl.handle.net/10962/434319 , vital:73048 , ISBN 978-1-78754-361-4 , https://www.emerald.com/insight/content/doi/10.1108/978-1-78754-361-420181002/full/html
- Description: Existing reviews of research on voluntary childlessness generally take the form of narrative summaries, focusing on main topics investigated over time. In this chapter, the authors extend previous literature reviews to conduct a systematic review and content analysis of socio-historical and geopolitical aspects of knowledge production about voluntary childlessness. The dataset comprised 195 peer-reviewed articles that were coded and analysed to explore, inter alia: the main topic under investigation; country location of authors; sample characteristics; theoretical framework and methodology. The findings are discussed in relation to the socio-historical contexts of knowledge production, drawing on theoretical insights concerned with the politics of location, representation and research practice. The shifts in the topics of research from the 1970s, when substantial research first emerged, uphold the view of voluntary childlessness as non-normative. With some regional variation, knowledge is dominated by quantitative, hard science methodologies and mostly generated about privileged, married women living in the global North. The implications of this for future research concerned with reproductive freedom are outlined.
- Full Text:
- Date Issued: 2018
- Authors: Lynch, Ingrid , Morison, Tracy , Macleod, Catriona I , Mijas, Magdalena , du Toit, Ryan , Shivakumar, Seemanthini T
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , book chapter
- Identifier: http://hdl.handle.net/10962/434319 , vital:73048 , ISBN 978-1-78754-361-4 , https://www.emerald.com/insight/content/doi/10.1108/978-1-78754-361-420181002/full/html
- Description: Existing reviews of research on voluntary childlessness generally take the form of narrative summaries, focusing on main topics investigated over time. In this chapter, the authors extend previous literature reviews to conduct a systematic review and content analysis of socio-historical and geopolitical aspects of knowledge production about voluntary childlessness. The dataset comprised 195 peer-reviewed articles that were coded and analysed to explore, inter alia: the main topic under investigation; country location of authors; sample characteristics; theoretical framework and methodology. The findings are discussed in relation to the socio-historical contexts of knowledge production, drawing on theoretical insights concerned with the politics of location, representation and research practice. The shifts in the topics of research from the 1970s, when substantial research first emerged, uphold the view of voluntary childlessness as non-normative. With some regional variation, knowledge is dominated by quantitative, hard science methodologies and mostly generated about privileged, married women living in the global North. The implications of this for future research concerned with reproductive freedom are outlined.
- Full Text:
- Date Issued: 2018
Glycosylated zinc phthalocyanine-gold nanoparticle conjugates for photodynamic therapy
- Dube, Edith, Oluwole, David O, Nwaji, Njemuwa, Nyokong, Tebello
- Authors: Dube, Edith , Oluwole, David O , Nwaji, Njemuwa , Nyokong, Tebello
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/234524 , vital:50205 , xlink:href="https://doi.org/10.1016/j.saa.2018.05.081"
- Description: In this work, we report on the synthesis of tris-[(2,2,7,7-tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-5-yl)methoxy)-2-(4-benzo[d]thiazol-2-ylphenoxyphthalocyaninato] zinc(II) (complex 3) and its linkage to gold nanoparticles (AuNPs) of different shapes through S-Au/N-Au self-assembly. The conjugates of complex 3 (with both gold nanorods (AuNR) and nanospheres (AuNS)), displayed decreased fluorescence quantum yield with corresponding improved triplet and singlet quantum yields compared to complex 3 alone, however 3-AuNR showed improved properties than 3-AuNS. Complex 3 showed relatively low in vitro dark cytotoxicity against the epithelial breast cancer cells with cell survival ≥ 85% at concentration ≤ 160 μg/mL but afforded reduced photodynamic therapy activity which may be due to aggregation. 3-AuNR afforded superior PDT activity with more than 50% viable cells at concentration ≥ 40 μg/mL in comparison to 3-AuNS with more than 50% viable cells at concentration ≥ 80 μg/mL. The superior activity of 3-AuNR is attributed to the photothermal therapy effect since nanorods absorb more light at 680 nm than nanospheres.
- Full Text:
- Date Issued: 2018
- Authors: Dube, Edith , Oluwole, David O , Nwaji, Njemuwa , Nyokong, Tebello
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/234524 , vital:50205 , xlink:href="https://doi.org/10.1016/j.saa.2018.05.081"
- Description: In this work, we report on the synthesis of tris-[(2,2,7,7-tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-5-yl)methoxy)-2-(4-benzo[d]thiazol-2-ylphenoxyphthalocyaninato] zinc(II) (complex 3) and its linkage to gold nanoparticles (AuNPs) of different shapes through S-Au/N-Au self-assembly. The conjugates of complex 3 (with both gold nanorods (AuNR) and nanospheres (AuNS)), displayed decreased fluorescence quantum yield with corresponding improved triplet and singlet quantum yields compared to complex 3 alone, however 3-AuNR showed improved properties than 3-AuNS. Complex 3 showed relatively low in vitro dark cytotoxicity against the epithelial breast cancer cells with cell survival ≥ 85% at concentration ≤ 160 μg/mL but afforded reduced photodynamic therapy activity which may be due to aggregation. 3-AuNR afforded superior PDT activity with more than 50% viable cells at concentration ≥ 40 μg/mL in comparison to 3-AuNS with more than 50% viable cells at concentration ≥ 80 μg/mL. The superior activity of 3-AuNR is attributed to the photothermal therapy effect since nanorods absorb more light at 680 nm than nanospheres.
- Full Text:
- Date Issued: 2018
HIV/AIDS and other household shocks as catalysts of local commercialization of non-timber forest products in Southern Africa
- Weyer, Dylan J, Shackleton, Charlie M, Adam, Y O
- Authors: Weyer, Dylan J , Shackleton, Charlie M , Adam, Y O
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/398223 , vital:69385 , xlink:href="https://doi.org/10.1111/dpr.12261"
- Description: Local trade in non-timber forest products (NTFPs) is increasing globally, yet the causes have been little studied. We examine household shock as a driver of NTFP trade in five southern African countries, with an emphasis on HIV/AIDS-related illness and death. Over the past two years, 95% of trader households experienced at least one shock, with family illness and death recorded for 68% and 42% of households, respectively. Almost 40% had entered the trade because of HIV/AIDS-related shocks. Additional shocks included natural disasters, crop pests or failure and livestock loss. The sale of NTFPs was the third most common coping strategy, after kinship and agricultural adjustments. Coping strategies differed between sites and type of shock.
- Full Text:
- Date Issued: 2018
- Authors: Weyer, Dylan J , Shackleton, Charlie M , Adam, Y O
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/398223 , vital:69385 , xlink:href="https://doi.org/10.1111/dpr.12261"
- Description: Local trade in non-timber forest products (NTFPs) is increasing globally, yet the causes have been little studied. We examine household shock as a driver of NTFP trade in five southern African countries, with an emphasis on HIV/AIDS-related illness and death. Over the past two years, 95% of trader households experienced at least one shock, with family illness and death recorded for 68% and 42% of households, respectively. Almost 40% had entered the trade because of HIV/AIDS-related shocks. Additional shocks included natural disasters, crop pests or failure and livestock loss. The sale of NTFPs was the third most common coping strategy, after kinship and agricultural adjustments. Coping strategies differed between sites and type of shock.
- Full Text:
- Date Issued: 2018
Household food insecurity along an agro-ecological gradient influences children’s nutritional status in South Africa
- Chakona, Gamuchirai, Shackleton, Charlie M
- Authors: Chakona, Gamuchirai , Shackleton, Charlie M
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/179836 , vital:43193 , xlink:href="https://doi.org/10.3389/fnut.2017.00072"
- Description: The burden of food insecurity and malnutrition is a severe problem experienced by many poor households and children under the age of five are at high risk. The objective of the study was to examine household food insecurity, dietary diversity, and child nutritional status in relation to local context which influences access to and ability to grow food in South Africa and explore the links and associations between these and household socio-economic status. Using a 48-h dietary recall method, we interviewed 554 women from randomly selected households along a rural–urban continuum in three towns situated along an agro-ecological gradient. The Household Dietary Diversity Scores (HDDS) and the Household Food Insecurity Access Scale (HFIAS) tools were used to measure household dietary diversity and food insecurity, respectively. Anthropometric measurements with 216 children (2–5 years) from the sampled households were conducted using height-for-age and mid-upper arm circumference (MUAC) as indicators of stunting and wasting, respectively. The key findings were that mean HDDS declined with decreasing agro-ecological potential from the wettest site (8.44 ± 1.72) to the other two drier sites (7.83 ± 1.59 and 7.76 ± 1.63). The mean HFIAS followed the opposite trend. Stunted growth was the dominant form of malnutrition detected in 35% of children and 18% of children were wasted. Child wasting was greatest at the site with lowest agro-ecological potential. Children from households with low HDDS had large MUAC which showed an inverse association among HDDS and obesity. Areas with agro-ecological potential had lower prevalence of food insecurity and wasting in children. Agro-ecological potential has significant influence on children’s nutritional status, which is also related to household food security and socio-economic status. Dependence on food purchasing and any limitations in households’ income, access to land and food, can result in different forms of malnutrition in children. Responses to address malnutrition in South Africa need to be prioritized and move beyond relying on food security and nutritional-specific interventions, but rather on nutrition-specific and sensitive programs and approaches; and building an enabling environment. Land availability, agriculture (including climate-smart agriculture especially in drier areas), and wild foods usage should be promoted.
- Full Text:
- Date Issued: 2018
- Authors: Chakona, Gamuchirai , Shackleton, Charlie M
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/179836 , vital:43193 , xlink:href="https://doi.org/10.3389/fnut.2017.00072"
- Description: The burden of food insecurity and malnutrition is a severe problem experienced by many poor households and children under the age of five are at high risk. The objective of the study was to examine household food insecurity, dietary diversity, and child nutritional status in relation to local context which influences access to and ability to grow food in South Africa and explore the links and associations between these and household socio-economic status. Using a 48-h dietary recall method, we interviewed 554 women from randomly selected households along a rural–urban continuum in three towns situated along an agro-ecological gradient. The Household Dietary Diversity Scores (HDDS) and the Household Food Insecurity Access Scale (HFIAS) tools were used to measure household dietary diversity and food insecurity, respectively. Anthropometric measurements with 216 children (2–5 years) from the sampled households were conducted using height-for-age and mid-upper arm circumference (MUAC) as indicators of stunting and wasting, respectively. The key findings were that mean HDDS declined with decreasing agro-ecological potential from the wettest site (8.44 ± 1.72) to the other two drier sites (7.83 ± 1.59 and 7.76 ± 1.63). The mean HFIAS followed the opposite trend. Stunted growth was the dominant form of malnutrition detected in 35% of children and 18% of children were wasted. Child wasting was greatest at the site with lowest agro-ecological potential. Children from households with low HDDS had large MUAC which showed an inverse association among HDDS and obesity. Areas with agro-ecological potential had lower prevalence of food insecurity and wasting in children. Agro-ecological potential has significant influence on children’s nutritional status, which is also related to household food security and socio-economic status. Dependence on food purchasing and any limitations in households’ income, access to land and food, can result in different forms of malnutrition in children. Responses to address malnutrition in South Africa need to be prioritized and move beyond relying on food security and nutritional-specific interventions, but rather on nutrition-specific and sensitive programs and approaches; and building an enabling environment. Land availability, agriculture (including climate-smart agriculture especially in drier areas), and wild foods usage should be promoted.
- Full Text:
- Date Issued: 2018
How important is green infrastructure in small and medium-sized towns? Lessons from South Africa
- Shackleton, Charlie M, Blair, Andrew, De Lacy, Peter, Kaoma, Humphrey, Mugwagwa, Noster, Dalu, Mwazvita, Walton, Wesley
- Authors: Shackleton, Charlie M , Blair, Andrew , De Lacy, Peter , Kaoma, Humphrey , Mugwagwa, Noster , Dalu, Mwazvita , Walton, Wesley
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/398321 , vital:69400 , xlink:href="https://doi.org/10.1016/j.landurbplan.2016.12.007"
- Description: The current nature and challenges of urbanisation in sub-Saharan Africa display several unique features only weakly evident on other continents. Key ones include the current high rates of population growth, inadequate planning and governance systems, concentration in small and medium-sized towns, and increasing urban poverty. These shape the extent, nature and use of ecosystem services provided by urban green infrastructure. This paper first examines the location of green infrastructure across nine towns, showing that it is unequal between suburbs and that the bulk is located under private tenure (74%) rather than in public spaces. We then consider the extent and patterns of use of selected provisioning and cultural ecosystem services from green infrastructure in different locations within towns, including private gardens, public parks and street trees. The results show significant use of green infrastructure for a range of provisioning and cultural services as well as its contribution to spiritual and mental wellbeing. Provisioning contributions are both in regular support of livelihood needs as well as increased use after a covariate shock (a flood), both of which help reduce household vulnerability. Lastly, our results show the expressed level of support and willingness-to-pay or work amongst urban residents for green infrastructure and the services it provides. Whilst the composite results indicate marked variation between and within towns, they show that there is widespread use of green infrastructure for both basic needs as well as for more aesthetic and psycho-spiritual appreciation and recreation, in small and medium-sized towns in a developing country such as South Africa.
- Full Text:
- Date Issued: 2018
- Authors: Shackleton, Charlie M , Blair, Andrew , De Lacy, Peter , Kaoma, Humphrey , Mugwagwa, Noster , Dalu, Mwazvita , Walton, Wesley
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/398321 , vital:69400 , xlink:href="https://doi.org/10.1016/j.landurbplan.2016.12.007"
- Description: The current nature and challenges of urbanisation in sub-Saharan Africa display several unique features only weakly evident on other continents. Key ones include the current high rates of population growth, inadequate planning and governance systems, concentration in small and medium-sized towns, and increasing urban poverty. These shape the extent, nature and use of ecosystem services provided by urban green infrastructure. This paper first examines the location of green infrastructure across nine towns, showing that it is unequal between suburbs and that the bulk is located under private tenure (74%) rather than in public spaces. We then consider the extent and patterns of use of selected provisioning and cultural ecosystem services from green infrastructure in different locations within towns, including private gardens, public parks and street trees. The results show significant use of green infrastructure for a range of provisioning and cultural services as well as its contribution to spiritual and mental wellbeing. Provisioning contributions are both in regular support of livelihood needs as well as increased use after a covariate shock (a flood), both of which help reduce household vulnerability. Lastly, our results show the expressed level of support and willingness-to-pay or work amongst urban residents for green infrastructure and the services it provides. Whilst the composite results indicate marked variation between and within towns, they show that there is widespread use of green infrastructure for both basic needs as well as for more aesthetic and psycho-spiritual appreciation and recreation, in small and medium-sized towns in a developing country such as South Africa.
- Full Text:
- Date Issued: 2018
Improved Photophysical and Photochemical Properties of Thiopheneethoxy Substituted Metallophthalocyanines on Immobilization onto Gold‐speckled Silica Nanoparticles
- Dube, Edith, Oluwole, David O, Nyokong, Tebello
- Authors: Dube, Edith , Oluwole, David O , Nyokong, Tebello
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/187699 , vital:44688 , xlink:href="https://doi.org/10.1111/php.12879"
- Description: This work reports on the synthesis of tetrakis-[(thiophineethoxy) phthalocyaninato] indium(II) chloride (3). The photophysical behavior of complex 3 was compared to that of the Zn derivative (tetrakis-[(thiophineethoxy) phthalocyaninato] zinc(II) (complex 2)). The compounds were interacted with gold-speckled silica (GSS) nanoparticles via Au–S self assembly to afford the conjugates (2–GSS and 3–GSS). The photophysicochemical behavior of the compounds and their conjugates were assessed. The conjugates afforded a decrease in fluorescence quantum yields and lifetimes with improved triplet and singlet oxygen quantum yields in comparison with complexes 2 and 3 alone. The complexes and their conjugates could serve as good candidates for photodynamic therapy.
- Full Text:
- Date Issued: 2018
- Authors: Dube, Edith , Oluwole, David O , Nyokong, Tebello
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/187699 , vital:44688 , xlink:href="https://doi.org/10.1111/php.12879"
- Description: This work reports on the synthesis of tetrakis-[(thiophineethoxy) phthalocyaninato] indium(II) chloride (3). The photophysical behavior of complex 3 was compared to that of the Zn derivative (tetrakis-[(thiophineethoxy) phthalocyaninato] zinc(II) (complex 2)). The compounds were interacted with gold-speckled silica (GSS) nanoparticles via Au–S self assembly to afford the conjugates (2–GSS and 3–GSS). The photophysicochemical behavior of the compounds and their conjugates were assessed. The conjugates afforded a decrease in fluorescence quantum yields and lifetimes with improved triplet and singlet oxygen quantum yields in comparison with complexes 2 and 3 alone. The complexes and their conjugates could serve as good candidates for photodynamic therapy.
- Full Text:
- Date Issued: 2018
In-situ synthesis of gold nanoparticles on graphene quantum dots-phthalocyanine nanoplatforms: First description of the photophysical and surface enhanced Raman scattering behaviour
- Nwahara, Nnamdi, Achadu, Ojodomo John, Nyokong, Tebello
- Authors: Nwahara, Nnamdi , Achadu, Ojodomo John , Nyokong, Tebello
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/187638 , vital:44682 , xlink:href="https://doi.org/10.1016/j.jphotochem.2018.04.011"
- Description: Owing to the need for new low-dimensional molecular assemblies with tailored electronic properties, the current study presents a facile approach for the synthesis and assembly of gold nanoparticles (AuNPs) onto functional graphene quantum dots (GQDs)-phthalocyanines (Pcs) arrays and the investigation of their photophysical and surface enhanced Raman scattering (SERS) properties. The GQDs were functionalized with L-glutathione (GSH) (to form GQDs@GSH) in order to assist coupling to the low symmetry Zn tris–(tert–butyl) mono carboxyphenoxy (propionic acid) phthalocyanine (complex 1) to form 1@GQDs. The affinity of gold (Au) to sulphur (S) was exploited for the assembly of the AuNPs onto 1@GQDs platform to form 1@GQDs-AuNPs. Transmission electron microscopic investigations confirmed the formation of monodispersed, spherical Pc/GQDs@GSH/AuNPs hybrids. The nanocomposite displayed high triplet quantum yields, which translated into high singlet oxygen quantum yield as high as 87%. Furthermore, the formed composites demonstrated strong surface enhanced Raman scattering (SERS) properties with an unprecedented intrinsic maximal enhancement factor of more than 30-fold. These nanostructures also retain more than 90% of their original SERS intensities after a week of storage, displaying superb stability under ambient conditions. These results highlight the remarkable potential of this composite as a unique Raman-based PDT dosimetric agent.
- Full Text:
- Date Issued: 2018
- Authors: Nwahara, Nnamdi , Achadu, Ojodomo John , Nyokong, Tebello
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/187638 , vital:44682 , xlink:href="https://doi.org/10.1016/j.jphotochem.2018.04.011"
- Description: Owing to the need for new low-dimensional molecular assemblies with tailored electronic properties, the current study presents a facile approach for the synthesis and assembly of gold nanoparticles (AuNPs) onto functional graphene quantum dots (GQDs)-phthalocyanines (Pcs) arrays and the investigation of their photophysical and surface enhanced Raman scattering (SERS) properties. The GQDs were functionalized with L-glutathione (GSH) (to form GQDs@GSH) in order to assist coupling to the low symmetry Zn tris–(tert–butyl) mono carboxyphenoxy (propionic acid) phthalocyanine (complex 1) to form 1@GQDs. The affinity of gold (Au) to sulphur (S) was exploited for the assembly of the AuNPs onto 1@GQDs platform to form 1@GQDs-AuNPs. Transmission electron microscopic investigations confirmed the formation of monodispersed, spherical Pc/GQDs@GSH/AuNPs hybrids. The nanocomposite displayed high triplet quantum yields, which translated into high singlet oxygen quantum yield as high as 87%. Furthermore, the formed composites demonstrated strong surface enhanced Raman scattering (SERS) properties with an unprecedented intrinsic maximal enhancement factor of more than 30-fold. These nanostructures also retain more than 90% of their original SERS intensities after a week of storage, displaying superb stability under ambient conditions. These results highlight the remarkable potential of this composite as a unique Raman-based PDT dosimetric agent.
- Full Text:
- Date Issued: 2018
In-situ synthesis of gold nanoparticles on graphene quantum dots-phthalocyanine nanoplatforms: First description of the photophysical and surface enhanced Raman scattering behaviour
- Nwahara, Nnamdi, Achadu, Ojodomo John, Nyokong, Tebello
- Authors: Nwahara, Nnamdi , Achadu, Ojodomo John , Nyokong, Tebello
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/188183 , vital:44730 , xlink:href="https://doi.org/10.1016/j.jphotochem.2018.04.011"
- Description: Owing to the need for new low-dimensional molecular assemblies with tailored electronic properties, the current study presents a facile approach for the synthesis and assembly of gold nanoparticles (AuNPs) onto functional graphene quantum dots (GQDs)-phthalocyanines (Pcs) arrays and the investigation of their photophysical and surface enhanced Raman scattering (SERS) properties. The GQDs were functionalized with L-glutathione (GSH) (to form GQDs@GSH) in order to assist coupling to the low symmetry Zn tris–(tert–butyl) mono carboxyphenoxy (propionic acid) phthalocyanine (complex 1) to form 1@GQDs. The affinity of gold (Au) to sulphur (S) was exploited for the assembly of the AuNPs onto 1@GQDs platform to form 1@GQDs-AuNPs. Transmission electron microscopic investigations confirmed the formation of monodispersed, spherical Pc/GQDs@GSH/AuNPs hybrids. The nanocomposite displayed high triplet quantum yields, which translated into high singlet oxygen quantum yield as high as 87%. Furthermore, the formed composites demonstrated strong surface enhanced Raman scattering (SERS) properties with an unprecedented intrinsic maximal enhancement factor of more than 30-fold. These nanostructures also retain more than 90% of their original SERS intensities after a week of storage, displaying superb stability under ambient conditions. These results highlight the remarkable potential of this composite as a unique Raman-based PDT dosimetric agent.
- Full Text:
- Date Issued: 2018
- Authors: Nwahara, Nnamdi , Achadu, Ojodomo John , Nyokong, Tebello
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/188183 , vital:44730 , xlink:href="https://doi.org/10.1016/j.jphotochem.2018.04.011"
- Description: Owing to the need for new low-dimensional molecular assemblies with tailored electronic properties, the current study presents a facile approach for the synthesis and assembly of gold nanoparticles (AuNPs) onto functional graphene quantum dots (GQDs)-phthalocyanines (Pcs) arrays and the investigation of their photophysical and surface enhanced Raman scattering (SERS) properties. The GQDs were functionalized with L-glutathione (GSH) (to form GQDs@GSH) in order to assist coupling to the low symmetry Zn tris–(tert–butyl) mono carboxyphenoxy (propionic acid) phthalocyanine (complex 1) to form 1@GQDs. The affinity of gold (Au) to sulphur (S) was exploited for the assembly of the AuNPs onto 1@GQDs platform to form 1@GQDs-AuNPs. Transmission electron microscopic investigations confirmed the formation of monodispersed, spherical Pc/GQDs@GSH/AuNPs hybrids. The nanocomposite displayed high triplet quantum yields, which translated into high singlet oxygen quantum yield as high as 87%. Furthermore, the formed composites demonstrated strong surface enhanced Raman scattering (SERS) properties with an unprecedented intrinsic maximal enhancement factor of more than 30-fold. These nanostructures also retain more than 90% of their original SERS intensities after a week of storage, displaying superb stability under ambient conditions. These results highlight the remarkable potential of this composite as a unique Raman-based PDT dosimetric agent.
- Full Text:
- Date Issued: 2018
Incorporation of metal free and Ga 5, 10, 15, 20-tetrakis (4-bromophenyl) porphyrin into Pluronic F127-folic acid micelles
- Managa, Muthumuni, Ngoy, Bucolome P, Mafukidze, Donovan M, Nyokong, Tebello
- Authors: Managa, Muthumuni , Ngoy, Bucolome P , Mafukidze, Donovan M , Nyokong, Tebello
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/233256 , vital:50073 , xlink:href="https://doi.org/10.1016/j.jlumin.2017.09.045"
- Description: ClGa 5,10,15,20-Tetrakis (4-bromophenyl) porphyrinato (ClGaTBrPP) and its metal free derivative were successfully synthesized and incorporated into Pluronic F127 polymeric micelles that has been conjugated to folic acid (FA) to form ClGaTBrPP-F127-FA (or H2TBrPP-F127-FA). For comparison, ClGaTBrPP-F127 and H2TBrPP-F127 (without FA) were also formed. The singlet oxygen quantum yield for ClGaTBrPP-F127-FA was higher (ΦΔ = 0.44) than that of H2TBrPP-F127-FA (ΦΔ = 0.37), due to the heavy atom effect of Ga in the former which encourages intersystem crossing to the triplet state. The same applies to ClGaTBrPP-F127 (ΦΔ = 0.47) and H2TBrPP-F127 (ΦΔ = 0.41). Thus, ΦΔ values decreased in the presence of FA, but still high enough for practical application of the nanodrug system. The binding constants Kb were determined to be 1.08 × 104 M−1, 2.51 × 105 M−1, 1.52 × 103 and 2.68 × 103 for H2TBrPP+F127-FA, ClGaTBrPP+F127-FA, ClGaTBrPP-F127 and H2TBrPP-F127, respectively. The Kp values were determined in biphasic octanol and water system.
- Full Text:
- Date Issued: 2018
- Authors: Managa, Muthumuni , Ngoy, Bucolome P , Mafukidze, Donovan M , Nyokong, Tebello
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/233256 , vital:50073 , xlink:href="https://doi.org/10.1016/j.jlumin.2017.09.045"
- Description: ClGa 5,10,15,20-Tetrakis (4-bromophenyl) porphyrinato (ClGaTBrPP) and its metal free derivative were successfully synthesized and incorporated into Pluronic F127 polymeric micelles that has been conjugated to folic acid (FA) to form ClGaTBrPP-F127-FA (or H2TBrPP-F127-FA). For comparison, ClGaTBrPP-F127 and H2TBrPP-F127 (without FA) were also formed. The singlet oxygen quantum yield for ClGaTBrPP-F127-FA was higher (ΦΔ = 0.44) than that of H2TBrPP-F127-FA (ΦΔ = 0.37), due to the heavy atom effect of Ga in the former which encourages intersystem crossing to the triplet state. The same applies to ClGaTBrPP-F127 (ΦΔ = 0.47) and H2TBrPP-F127 (ΦΔ = 0.41). Thus, ΦΔ values decreased in the presence of FA, but still high enough for practical application of the nanodrug system. The binding constants Kb were determined to be 1.08 × 104 M−1, 2.51 × 105 M−1, 1.52 × 103 and 2.68 × 103 for H2TBrPP+F127-FA, ClGaTBrPP+F127-FA, ClGaTBrPP-F127 and H2TBrPP-F127, respectively. The Kp values were determined in biphasic octanol and water system.
- Full Text:
- Date Issued: 2018
Influence of land cover, proximity to streams and household topographical location on flooding impact in informal settlements in the Eastern Cape, South Africa
- Dalu, Mwazvita, Shackleton, Charlie M, Dalu, Tatenda
- Authors: Dalu, Mwazvita , Shackleton, Charlie M , Dalu, Tatenda
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/182089 , vital:43799 , xlink:href="https://doi.org/10.1016/j.ijdrr.2017.12.009"
- Description: Patterns of land use, household topographical location and state of natural vegetation influence the spatial distribution of flooding impact. Using field observations and GIS mapping techniques, we investigated how landscape factors influenced structural flooding impact in informal settlements. This study was carried out in the informal settlements of the Eastern Cape Province of South Africa, after the October 2012 floods. Increasing slope significantly raised the probability and level of damage by at least 30% in five of the seven sites, whereas proximity to river and wetlands (more than 100 m) was significant in only two of the sites and at lower levels. Multi-regression analysis highlighted that land cover, proximity to streams and household topographical location influenced the impact of flooding on housing structures. We found that the impact on housing structures in informal settlements during the floods were significantly influenced by their proximity to water bodies, slope factor and patterns of land cover.
- Full Text:
- Date Issued: 2018
- Authors: Dalu, Mwazvita , Shackleton, Charlie M , Dalu, Tatenda
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/182089 , vital:43799 , xlink:href="https://doi.org/10.1016/j.ijdrr.2017.12.009"
- Description: Patterns of land use, household topographical location and state of natural vegetation influence the spatial distribution of flooding impact. Using field observations and GIS mapping techniques, we investigated how landscape factors influenced structural flooding impact in informal settlements. This study was carried out in the informal settlements of the Eastern Cape Province of South Africa, after the October 2012 floods. Increasing slope significantly raised the probability and level of damage by at least 30% in five of the seven sites, whereas proximity to river and wetlands (more than 100 m) was significant in only two of the sites and at lower levels. Multi-regression analysis highlighted that land cover, proximity to streams and household topographical location influenced the impact of flooding on housing structures. We found that the impact on housing structures in informal settlements during the floods were significantly influenced by their proximity to water bodies, slope factor and patterns of land cover.
- Full Text:
- Date Issued: 2018