Secondary metabolites from Tetracera potatoria stem bark with anti-mycobacterial activity.

Fomogne-Fodjo, M C Y; Ndinteh, Derek T; Olivier, Denise K; Krause, Rui W M; Kempgens, Pierre; Van Vuuren, S

Title: Secondary metabolites from Tetracera potatoria stem bark with anti-mycobacterial activity.
Creator: Fomogne-Fodjo, M C Y
Creator: Ndinteh, Derek T
Creator: Olivier, Denise K
Creator: Krause, Rui W M
Creator: Kempgens, Pierre
Creator: Van Vuuren, S
Date Issued: 2017
Date: 2017
Type: text
Type: article
Identifier: http://hdl.handle.net/10962/125556
Identifier: vital:35795
Identifier: https://doi.org/10.1016/j.jep.2016.11.027
Description: Ethnopharmacological relevance Tetracera potatoria Afzel. Exg. Don (Dilleniaceae) is a medicinal plant used traditionally in Africa for the treatment of tuberculosis related ailments and respiratory infections. The antibacterial activity of the medium polar extracts of T. potatoria leaves and stem bark was recently reported against Mycobacterium smegmatis (MIC 25 µg/mL) and M. aurum (65 µg/mL), two fast-growing Mycobacterium strains used as model micro-organisms for the more pathogenic strain Mycobacterium tuberculosis (Fomogne-Fodjo et al., 2014). The aim of this study was consequently to isolate the compounds possibly contributing to this activity, and which may therefore be promising precursors to be used for the development of novel anti-TB drugs.
Format: 8 pages
Format: pdf
Language: English
Relation: Journal of ethnopharmacology
Relation: Fomogne-Fodjo, M.C.Y., Ndinteh, D.T., Olivier, D.K., Kempgens, P., Van Vuuren, S. and Krause, R.W.M., 2017. Secondary metabolites from Tetracera potatoria stem bark with anti-mycobacterial activity. Journal of ethnopharmacology, 195, pp.238-245.
Relation: Journal of ethnopharmacology number 195 238 245 2017 1872-7573
Rights: Journal of ethnopharmacology
Rights: Use of this resource is governed by the terms and conditions of the Royal Society of Chemistry Terms & Conditions Statement (http://www.rsc.org/help-legal/)

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Krause, Rui Werner Maçedo (Prof)

RU Department of Chemistry

SDG 03. Good Health and Well-Being

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