Studies on an autolysin produced by clostridium acetobutylicum

Title: Studies on an autolysin produced by clostridium acetobutylicum
Creator: Webster, Jocelyn Rowena
Subject: Clostridium acetobutylicum
Subject: Autolysis
Subject: Bacteriocins
Subject: Proteins -- Synthesis
Subject: DNA -- Synthesis
Subject: RNA -- Synthesis
Date Issued: 1981
Date: 1981
Type: Thesis
Type: Masters
Type: MSc
Identifier: vital:3893
Identifier: http://hdl.handle.net/10962/d1003724
Description: An extracellular bacteriocin-like substance produced by Clostridium acetobutylicum was detected during studies on an industrial fermentation process. The bacteriocin-like substance was not inducible by either ultraviolet light or mitomycin C, and its production was not associated with the induction of a protease. Studies on the mode of action of the bacteriocin-like substance indicated that it had no significant effect on DNA, RNA, or protein synthesis, and it did not cause the loss of intracellular ATP. However, the bacteriocin-like substance was able to lyse SDS-treated cells and cell walls of C. acetobutylicum and was identified as an autolysin. Some of the characteristics of this extracellular autolysin were determined, and after purification it was shown to be a glycoprotein with a molecular weight of 28 000.
Format: 137 leaves
Format: pdf
Publisher: Rhodes University
Publisher: Faculty of Science, Biochemistry and Microbiology
Language: English
Rights: Webster, Jocelyn Rowena

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