List of Titles

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The use of supersaturated solutions for the percutaneous delivery of rooperol tetra-acetate

- Pefile, S C, Haigh, John M, Smith, Eric W

Authors: Pefile, S C , Haigh, John M , Smith, Eric W
Date: 1998
Language: English
Type: Conference paper , text
Identifier: vital:6340 , http://hdl.handle.net/10962/d1006537
Description: A major problem encountered in the transdermal delivery of drugs is the effectiveness of the barrier system imposed by the stratum corneum.To overcome tbe resistance of the skin to the ingress of exogenous chemicals, numerous innovative techniques requiring complex delivery systems have been studied. Many of these systems attempt to alter the barrier potential by the use of enhancer technology. Supersaturation, on the other hand, is a simple and economical technique which is not intended to modify the physical structure or the chemical composition of the stratum corneum, yet may effectively deliver a markedly greater mass of drug to the skin than that achieved by the use of conventional, saturated solutions. Supersaturated systems make use of the elevated thermodynamic activity of the permeant in the delivery vehicle, which results in higher flux rates across the contacting membrane by increasing the concentration gradient. The present study investigated the potential for using supersaturation techniques to transdermally deliver rooperol tetra-acetate (RTA), a lipophilic, cytotoxic agent with potential for use in the treatment of solar keratosis. The diffusion characteristics of the drug from a 60% propylene glycol/water supersaturated solution across silicone membrane and full thickness rat skin were studied using Franz diffusion cells. A comparison was made of the drug diffusion rates from a saturated system and from supersaturated systems prepared with and without an antinucleating agent.
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Date Issued: 1998

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Bells and bellfounders of the Eastern Cape, South Africa

- Lewis, Colin A

Authors: Lewis, Colin A
Date: 1997
Language: English
Type: Article
Identifier: vital:6179 , http://hdl.handle.net/10962/d1012372 , http://www.ringingworld.co.uk
Description: [From Introduction] Although there is only one ring of bells in the whole of the Eastern Cape almost every church, and many chapels, have one or more bells. No systematic study of these bells had yet been made, but cursory examination suggests that many British founders exported bells to that area in the late 19th century and in the 20th century. American founders of steel bells also peddled their wares with considerable success. The Irish bell founder: Matthew O'Byrne sold at least five bells to clients in the Eastern Cape, the largest of which weighed 16 cwts. In the 1950s the Swiss founder, Ruetschi, of Aarau, cast at least four beautiful bells that are now in the Transkei. , Colin Lewis was Professor of Geography at Rhodes University, Grahamstown, South Africa from 1989 until his retirement at the end of 2007. In 1990, with the strong support of the incumbent Vice-Chancellor, Dr Derek Henderson, he instigated the Certificate in Change Ringing (Church Bell Ringing) in the Rhodes University Department of Music and Musicology - the first such course to be offered in Africa. Since that date he has lectured in the basic theory, and taught the practice of change ringing. He is the Ringing Master of the Cathedral of St Michael and St George, Grahamstown, South Africa.
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Date Issued: 1997

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Profile on CWIU

- Chemical Workers Industrial Union (CWIU)

Authors: Chemical Workers Industrial Union (CWIU)
Date: 1996
Subjects: CWIU
Language: English
Type: text
Identifier: http://hdl.handle.net/10962/170170 , vital:41864
Description: Chemical Workers Industrial Union (GW1U) CW1U wus launched in November 1074 following a wuvo of strikes by workers in Durban, who wero demanding bettor wages. During those dark yours when repression wus at its highest peak, workers hud no hade unions to assist them. In chemical, transport, textile and .paper industries, workers formed trade unions to take their struggle forward. They also formed a tight .federation, the Trade Union Advisory and Co-ordinating Committee (TUACC). At its launch in 1974, CWIU was concentrated in Durban and had just under 1 000 members. In July 1980, a branch was opened in the "old” Transvaal. In building a national union, CWIU merged with Glass and Allied Workers Union (Gawu) in 1982. In the interim, other branches where launched throughout the country, though it was easy task with security cops keeping surveillance on every movement of union officials. To build a stronger united worker-front, CWIU took quantum leap when it merged again with Plastics and Allied Workers Union in 1986.
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Date Issued: 1996

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The use of wood ash for the protection of stored cowpea seed (Vigna unguiculata (L.) Walp.) against Bruchidae (Coleoptera)

- Katanga Apuuli, J, Villet, Martin H

Authors: Katanga Apuuli, J , Villet, Martin H
Date: 1996
Language: English
Type: Article
Identifier: vital:6864 , http://hdl.handle.net/10962/d1011196
Description: Dry wood-ash has been reported to provide effective, cheap and safe control of several pests of stored seeds by providing mechanical protection, especially if it is thoroughly mixed with the seed. Mixtures of seed and either clays, ash, talc, or sand are among the earliest recommendations for controlling bruchids in beans (Metcalf 1917; Headlee 1924; Subramanian 1935; Deay & Amos 1936; Lever 1941). Such use of ash has been reported on subsistence farms in Uganda (Davies 1970). However, little is known of the actual ratios of ash and beans needed for effective protection, or of the mechanism of protection. These issues motivated this investigation.
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Date Issued: 1996

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The effects of elevated and ambient temperature conditions on dilutions of fluocinolone acetonide ointment assessed using the human skin-blanching assay

- Haigh, John M, Smith, Eric W

Authors: Haigh, John M , Smith, Eric W
Date: 1995
Language: English
Type: text , Article
Identifier: vital:6380 , http://hdl.handle.net/10962/d1006298
Description: Topical corticosteroid formulations have been in use now for some 30 years and many methods are available for the in vivo assessment of these preparations. Of all the assays described in the literature, the one first advocated by McKenzie and Stoughton, the so-called vasoconstrictor assay, is one of the most reliable if performed by experienced researchers using - the optimised methodology. Topical application of corticosteroids produces a whitening (blanching) of the skin, the intensity of which is directly proportional to the clinical efficacy of the formulation. Assessment of the degree of blanching produced is therefore of use in determining the rate and extent of corticosteroid release' from the semi-solid base through the stratum corneum. Since it is the degree of blanching which is measured, we prefer to call this test the human skin blanching assay. Some of the main advantages of this assay technique are that normal healthy skin is used therefore persons with dermatological complaints are not compromised, it is not painful for the volunteers, it is non-invasive and several formulations can be evaluated simultaneously. Most commercially available topical corticosteroid preparations have been formulated in such a way as to provide optimum release of the active ingredient from the base through the stratum corneum. Despite this fact, many practitioners often prescribe dilutions of topical corticosteroid formulations, presumably in an effort to reduce the unwanted side effects. This could be problematic; dilution with an incompatible base could destroy the delivery environment thus considerably reducing the efficacy of the formulation. The method of dilution could also play a role in the suitability of the final preparation. The objective of this work was to determine the effects of two different dilutions of fluocinolone ointment at both ambient and elevated temperature on the blanching produced by the dilutions and, by inference, the relative clinical efficacies of these dilutions compared to the full strength product.
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Date Issued: 1995

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First Democratic Elections

- NUMSA

Authors: NUMSA
Date: 1993
Subjects: NUMSA
Language: English
Type: text
Identifier: http://hdl.handle.net/10962/110159 , vital:33238
Description: Every member is free to join any political party. NUMSA will encourage its members to vote ANC because it wants a strong government to fix up the country's and workers' problems. NUMSA members must not force anyone to vote for the ANC or any other party. NUMSA members must be free to vote (or not vote) for whoever they want. It is your right to vote; it is also your right not to vote. BUT you may not force anyone to vote or not vote. Voting stations will be in places like schools, community halls. Ask and discuss with your fellow workers, ask at NUMSA or COSATU offices, listen to your radio, look for posters and pamphlets nearer election time to find out.
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Date Issued: 1993

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NUMSA workers: Prepare for war

- NUMSA

Authors: NUMSA
Date: May 1992
Subjects: NUMSA
Language: English
Type: text
Identifier: http://hdl.handle.net/10962/112697 , vital:33639
Description: ON May 14, a dispute was declared with SEIFSA, the engineering bosses, because no progress had been made in negotiations. As you can see from the table over the page, there is hardly any progress in NUMSA’s other sectors either. Motor employers didn’t even respond to NUMSA’s demands - they just came with their own demands! On May 24 a special NUMSA Bargaining Unit Workshop will take place. This is to get reports from regions and to give NUMSA’s bargaining reps a mandate to go to the SEIFSA dispute meeting on May 26. Make sure you get a report about these meetings and make sure you and your shop steward attend all report back meetings in your region and locals. If you want to win your demands you must decide what action you will take! Comrades, we have to ask ourselves - Why is there such a deadlock between the bosses and ourselves?
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Date Issued: May 1992

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Metalworkers prepare to Fight for a Living Wage

- NUMSA

Authors: NUMSA
Date: 1990
Subjects: NUMSA
Language: English
Type: text
Identifier: http://hdl.handle.net/10962/110675 , vital:33321
Description: The NUMSA 1990 Living Wage Campaign is starting to move. After a slow start NUMSA members are gearing up for the big fight. We are going through big changes in South Africa. We want to tell the bosses and De Klerk: the workers will never end the struggle lor a Living Wage, jobs for all, houses for all, proper health care for all. De Klerk must meet our demands. We want to end the system that gives the bosses freedom to exploit workers. Our battle cry this year is: Our Industry, Our Country, Forward to Workers' Control. In February this year NUMSA/Es National Bargaining Conference set-out the workers demand.
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Date Issued: 1990

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NUMSA in 1990 - Grow, lead and move to financial self-sufficiency

- NUMSA

Authors: NUMSA
Date: Feb 1990
Subjects: NUMSA
Language: English
Type: text
Identifier: http://hdl.handle.net/10962/113010 , vital:33685
Description: NUMSA is fully committed to playing an active role in the liberation of the working class and ending the oppression of our people. To do this we have set ourselves certain very important tasks in 1990. They are: To strengthen and democratise our union in order to improve conditions for our members, To actively work in our federation COSATU to strengthen it an to greatly improve our working relationship with other affiliates. To contribute to the liberation struggle by using our strength together with the MDM to defeat oppression and exploitation To play an active role in the community struggles in our land particularly in areas such as the Natal violence To actively contribute to developing programmes for a future South Africa based on democracy and socialist planning to improve the lives of all people, To make our organisation administratively efficient and to develop the skills of leadership, organisers and administrators. To become financially self-sufficient.
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Date Issued: Feb 1990

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Black Sash - Untitled letter to Dr. F van Zyl Slabbert

- Douglas-Jones, Isobel, Black Sash (Society)

Authors: Douglas-Jones, Isobel , Black Sash (Society)
Date: 1987-08-20
Subjects: Apartheid -- South Africa , South Africa -- Politics and government , Government Resistance to – South Africa , Black Sash (Society) -- Letters and correspondence , Slabbert, F. van Zyl (Frederik van Zyl), 1940-2010 , Institute for a Democratic Alternative for South Africa (IDASA)
Language: English
Type: text , letter
Identifier: http://hdl.handle.net/10962/57762 , vital:26987 , This item is held at the Cory Library for Humanities Research at Rhodes University. For further information contact cory@ru.ac.za. The digitisation of this image was made possible through a generous grant received from the Andrew W. Mellon Foundation 2014-2017.
Description: Letter written by the Chairman of the Blask Sash Cape Eastern Region, Isobel Douglas-Jones, to Dr F. van Zyl Slabbert, thanking him for his contribution (in the form of a speech) to the Sash/IDAMASA Public meeting held on the 6th of August 1987 in Port Elizabeth. Letter dated 20 August 1987.
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Date Issued: 1987-08-20

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Rumours of spying

- Rhodes University. Students' Representative Council

Authors: Rhodes University. Students' Representative Council
Date: 1987-03-07
Subjects: Apartheid -- South Africa , South Africa -- Politics and government , Propaganda, South African , Government Resistance to – South Africa , Vincent, Louise , Knight, Janet , Espionage -- South Africa , Spies -- South Africa
Language: English
Type: text , tracts (ephemera)
Identifier: http://hdl.handle.net/10962/57715 , vital:26984 , This item is held at the Cory Library for Humanities Research at Rhodes University. For further information contact cory@ru.ac.za. The digitisation of this image was made possible through a generous grant received from the Andrew W. Mellon Foundation 2014-2017.
Description: A response from NUSAS SRC at Rhodes University, about allegations (published in The Star newspaper dated 17 February 1987) about two members of the Rhodes community acting as informants.
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Date Issued: 1987-03-07

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