Assessing the implementation of performance management policies in the public service: a case study of the Department of Human Settlements in the Eastern Cape Province
- Authors: Sandiso, Mahlala
- Date: 2014
- Language: English
- Type: Thesis , Masters , MPA
- Identifier: http://hdl.handle.net/10353/1183 , vital:26534
- Description: This dissertation set out to assess the implementation of performance management policies in the public service using the case study of the Eastern Cape Department of Housing known currently as Human Settlements. It examines how monitoring and evaluation policies are important in governance deliverables, such as transparency, accountability and learning, influences public administration practice. The exchange between democracy and monitoring and evaluation was demonstrated by assessing how the country managed democratic transition, the influence of globalization on country practice, and specifically how the developmental state advances governance. It also focused on other focal points of how performance management policies in the public service are being utilized to assist Eastern Cape Department of Human Settlements. The study looked at the „new‟ role of performance management systems in meeting „performance information needs‟ of public sector managers as a potential area for further research. This type of research is qualitative in nature as it used documents to elaborate on matters. This study uses documents of the department as a case study to gain more insight about the department as well as the theory of change to guide the study.
- Full Text:
- Date Issued: 2014
- Authors: Sandiso, Mahlala
- Date: 2014
- Language: English
- Type: Thesis , Masters , MPA
- Identifier: http://hdl.handle.net/10353/1183 , vital:26534
- Description: This dissertation set out to assess the implementation of performance management policies in the public service using the case study of the Eastern Cape Department of Housing known currently as Human Settlements. It examines how monitoring and evaluation policies are important in governance deliverables, such as transparency, accountability and learning, influences public administration practice. The exchange between democracy and monitoring and evaluation was demonstrated by assessing how the country managed democratic transition, the influence of globalization on country practice, and specifically how the developmental state advances governance. It also focused on other focal points of how performance management policies in the public service are being utilized to assist Eastern Cape Department of Human Settlements. The study looked at the „new‟ role of performance management systems in meeting „performance information needs‟ of public sector managers as a potential area for further research. This type of research is qualitative in nature as it used documents to elaborate on matters. This study uses documents of the department as a case study to gain more insight about the department as well as the theory of change to guide the study.
- Full Text:
- Date Issued: 2014
Evaluation of the efficacy of Carpobrotus edulis (L.) bolus leaf as a traditional treatment for the management of HIV/AIDS
- Authors: Omoruyi, Beauty Etinosa
- Date: 2014
- Subjects: AIDS (Disease) -- Treatment -- South Africa -- Eastern Cape , Phytochemicals -- South Africa -- Eastern Cape , Traditional medicine -- South Africa -- Eastern Cape , Carpobrotus
- Language: English
- Type: Thesis , Doctoral , PhD (Biochemistry)
- Identifier: http://hdl.handle.net/10353/744 , vital:26493 , AIDS (Disease) -- Treatment -- South Africa -- Eastern Cape , Phytochemicals -- South Africa -- Eastern Cape , Traditional medicine -- South Africa -- Eastern Cape , Carpobrotus
- Description: The human immunodeficiency virus (HIV) is one of the most common and dreaded diseases of the 21th century. Today, the disease is still spreading with increasing incidence. “Since the beginning of the epidemic, almost 75 million people have been infected with the HIV virus and about 36 million people have died of HIV. Globally, 35.3 million [32.2–38.8 million] people were living with HIV at the end of 2012” (http://www.who.int/gho/hiv/en/). Several studies have been conducted on herbs under a multitude of ethnobotanical grounds. The use of medicinal plants for the management of HIV has become a common practice especially, in the Eastern Cape Province of South Africa (Wilfred Otang Mbeng, 2013 PhD thesis, UFH). At the beginning of this programme, an ethnomedicinal survey of plants used for the management of HIV infection was carried out in targeted areas of the Province and information on the names of plants, the parts and the methods of preparation were collected. The survey revealed that 18 species representing 12 families were found to be commonly used for the management of HIV, as well as other opportunistic diseases such as tuberculosis, diabetes mellitus, sores, high blood pressure, etc. Carpobrotus edulis was selected for this research because it was the most frequently used in the Province. The foliar micro morphological contents of the plant, its phytochemical and antioxidant activity, in vitro antimicrobial activity, inhibitory effect against HIV-1 protease and reverse transcriptase, mechanisms of action and cytotoxicity were investigated. In terms of the foliar micro morphological contents in plants, an electron microscopy scanning (SEM) was completed. Investigation revealed that both glandular tricomes and calcium oxalate crystals (CaOX) were observed. Consequently, it is hypothesized that the bioactive therapeutic compounds secreted by C. edulis may be produced in the glandular trichomes. An investigation of phytochemical content of the plant extracts (C. edulis) was completed using four solvent extracts (hexane, acetone, ethanol and water). Results of the phytochemical analysis showed that proanthocyanidins (86.9 ± 0.005%) where highest in the aqueous extract with phenolics at 55.7 ± 0.404% in acetone extract, tannin at 48.9 ± 0.28% in ethanol extract, while the hexane extract had the highest levels of flavonoids (0.12 ± 0.05%) and flavonols (0.12 ± 0.05%). Antioxidant studies of the various extracts revealed that aqueous and ethanol extracts were found to be the best solvents for antioxidant activity in C. edulis leaves. GC-MS analysis of the essential oil from C. edulis leaves revealed that the essential oil contained at least 28 compounds. These included, in order of abundance: Oxygenated monoterpenes (36.61%); fatty acids esters (19.25%); oxygenated diterpenes (19.24%); monoterpenes (10.6%); sesquiterpenes (3.58%); and diterpenes (1.43%). Similarly, a GC-MS analysis of the crude hexane, acetone and ethanol extracts from C. edulis leaves identified a total of 59 compounds. Of the 59 compounds, 12 major phyto-metabolites that are active against infectious diseases were identified. To comfirm the potential use of C. edulis to treat infectious disease, antifungal activity of the crude essential oil extract and the four solvent extracts were tested against Candida albicans, Candida krusei, Candida glabrata, Candida rugosa and Cryptococcus neoformans strains. The essential oil extract was found to be the most active against all the fungal strains tested and performed better than the four extracts used various solvents used to extract (hexane, acetone, ethanol and water) the C. edulis leaves were tested for antibacterial and anti HIV-1 reverse transcriptase (RT) activity. The results indicated that both gram-positive and gram-negative isolates were inhibited by the extracts (hexane, acetone and ethanol) but antimicrobial activity was observed for the water extract. The lowest minimum inhibitory concentration values were obtained for the ethanol extract, followed by acetone and hexane extracts. No inhibition of HIV-1 reverse transcriptase was observed for any of the leaf extracts, even up to concentrations of 16 mg/ml. The potential inhibitory activities of the various solvent extracts against HIV-1 protease were evaluated at four different concentrations (16, 1.6, 0.16 and 0.016 mg/ml). Results indicated that the water extract showed almost 100% inhibition of HIV-1 protease activity, with an IC50 of 0.86 mg/ml leaf extract. Other solvent extracts (hexane, acetone and ethanol) however, did not show any inhibition activity above that observed for the DMSO control. The metabolic components in the water extract were subjected to LC-MS/MS analysis, which identified at least 91 compounds present in the water extract. Further studies involving the molecular modelling need to be carried out to confirm the inhibitory potential of these compounds. The cytotoxicity of the water extract of C. edulis leaves was also screened using human Chang liver cells at concentrations ranging bewteen 0.005 mg/ml and 1 mg/ml. Results indicated that the water extracts were not toxic. In conclusion the results from this study support the use of water extracts of C. edulis leaves by traditional healers to treat HIV infections and have identified possible mechanisms of action of the water extracts of C. edulis.
- Full Text:
- Date Issued: 2014
- Authors: Omoruyi, Beauty Etinosa
- Date: 2014
- Subjects: AIDS (Disease) -- Treatment -- South Africa -- Eastern Cape , Phytochemicals -- South Africa -- Eastern Cape , Traditional medicine -- South Africa -- Eastern Cape , Carpobrotus
- Language: English
- Type: Thesis , Doctoral , PhD (Biochemistry)
- Identifier: http://hdl.handle.net/10353/744 , vital:26493 , AIDS (Disease) -- Treatment -- South Africa -- Eastern Cape , Phytochemicals -- South Africa -- Eastern Cape , Traditional medicine -- South Africa -- Eastern Cape , Carpobrotus
- Description: The human immunodeficiency virus (HIV) is one of the most common and dreaded diseases of the 21th century. Today, the disease is still spreading with increasing incidence. “Since the beginning of the epidemic, almost 75 million people have been infected with the HIV virus and about 36 million people have died of HIV. Globally, 35.3 million [32.2–38.8 million] people were living with HIV at the end of 2012” (http://www.who.int/gho/hiv/en/). Several studies have been conducted on herbs under a multitude of ethnobotanical grounds. The use of medicinal plants for the management of HIV has become a common practice especially, in the Eastern Cape Province of South Africa (Wilfred Otang Mbeng, 2013 PhD thesis, UFH). At the beginning of this programme, an ethnomedicinal survey of plants used for the management of HIV infection was carried out in targeted areas of the Province and information on the names of plants, the parts and the methods of preparation were collected. The survey revealed that 18 species representing 12 families were found to be commonly used for the management of HIV, as well as other opportunistic diseases such as tuberculosis, diabetes mellitus, sores, high blood pressure, etc. Carpobrotus edulis was selected for this research because it was the most frequently used in the Province. The foliar micro morphological contents of the plant, its phytochemical and antioxidant activity, in vitro antimicrobial activity, inhibitory effect against HIV-1 protease and reverse transcriptase, mechanisms of action and cytotoxicity were investigated. In terms of the foliar micro morphological contents in plants, an electron microscopy scanning (SEM) was completed. Investigation revealed that both glandular tricomes and calcium oxalate crystals (CaOX) were observed. Consequently, it is hypothesized that the bioactive therapeutic compounds secreted by C. edulis may be produced in the glandular trichomes. An investigation of phytochemical content of the plant extracts (C. edulis) was completed using four solvent extracts (hexane, acetone, ethanol and water). Results of the phytochemical analysis showed that proanthocyanidins (86.9 ± 0.005%) where highest in the aqueous extract with phenolics at 55.7 ± 0.404% in acetone extract, tannin at 48.9 ± 0.28% in ethanol extract, while the hexane extract had the highest levels of flavonoids (0.12 ± 0.05%) and flavonols (0.12 ± 0.05%). Antioxidant studies of the various extracts revealed that aqueous and ethanol extracts were found to be the best solvents for antioxidant activity in C. edulis leaves. GC-MS analysis of the essential oil from C. edulis leaves revealed that the essential oil contained at least 28 compounds. These included, in order of abundance: Oxygenated monoterpenes (36.61%); fatty acids esters (19.25%); oxygenated diterpenes (19.24%); monoterpenes (10.6%); sesquiterpenes (3.58%); and diterpenes (1.43%). Similarly, a GC-MS analysis of the crude hexane, acetone and ethanol extracts from C. edulis leaves identified a total of 59 compounds. Of the 59 compounds, 12 major phyto-metabolites that are active against infectious diseases were identified. To comfirm the potential use of C. edulis to treat infectious disease, antifungal activity of the crude essential oil extract and the four solvent extracts were tested against Candida albicans, Candida krusei, Candida glabrata, Candida rugosa and Cryptococcus neoformans strains. The essential oil extract was found to be the most active against all the fungal strains tested and performed better than the four extracts used various solvents used to extract (hexane, acetone, ethanol and water) the C. edulis leaves were tested for antibacterial and anti HIV-1 reverse transcriptase (RT) activity. The results indicated that both gram-positive and gram-negative isolates were inhibited by the extracts (hexane, acetone and ethanol) but antimicrobial activity was observed for the water extract. The lowest minimum inhibitory concentration values were obtained for the ethanol extract, followed by acetone and hexane extracts. No inhibition of HIV-1 reverse transcriptase was observed for any of the leaf extracts, even up to concentrations of 16 mg/ml. The potential inhibitory activities of the various solvent extracts against HIV-1 protease were evaluated at four different concentrations (16, 1.6, 0.16 and 0.016 mg/ml). Results indicated that the water extract showed almost 100% inhibition of HIV-1 protease activity, with an IC50 of 0.86 mg/ml leaf extract. Other solvent extracts (hexane, acetone and ethanol) however, did not show any inhibition activity above that observed for the DMSO control. The metabolic components in the water extract were subjected to LC-MS/MS analysis, which identified at least 91 compounds present in the water extract. Further studies involving the molecular modelling need to be carried out to confirm the inhibitory potential of these compounds. The cytotoxicity of the water extract of C. edulis leaves was also screened using human Chang liver cells at concentrations ranging bewteen 0.005 mg/ml and 1 mg/ml. Results indicated that the water extracts were not toxic. In conclusion the results from this study support the use of water extracts of C. edulis leaves by traditional healers to treat HIV infections and have identified possible mechanisms of action of the water extracts of C. edulis.
- Full Text:
- Date Issued: 2014
The influence of gender on access to venture capital and firm performance in small, medium and micro enterprises in King Williams Town, South Africa
- Authors: Shava, Herring
- Date: 2014
- Subjects: Small business -- South Africa -- Eastern Cape , Venture capital -- South Africa -- Eastern Cape , Entrepreneurship -- South Africa -- Eastern Cape , Sex discrimination -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , M Com (Business Management)
- Identifier: http://hdl.handle.net/10353/767 , vital:26495 , Small business -- South Africa -- Eastern Cape , Venture capital -- South Africa -- Eastern Cape , Entrepreneurship -- South Africa -- Eastern Cape , Sex discrimination -- South Africa -- Eastern Cape
- Description: This study examined the influence of gender on access to venture capital and firm performance on Small, Medium and Micro Enterprises in King Williams Town, South Africa. This study sought to establish whether there was differential access to venture capital between genders; to establish whether men- and women-owned SMMEs differ in performance; to identify whether an association between gender and business related experience can be found; and to assess the extent to which the gender gap in SMME access to venture capital and performance could be allocated to gender differences in levels of business related experience. A total sample of 109 SMMEs was used which comprised 53 female- and 56 male-owned. The quota sampling technique was implemented and a self-administered questionnaire was used for the purpose of gathering primary data. Data for this study was gathered from SMME owners only as they were the targeted respondents. The t-test and Chi-square test were used for the statistical analysis in order to arrive at findings and conclusions. Based on a 64% survey response rate, the study reports the existence of statistically significant gender gap in SMME access to venture capital and SMME performance. In addition, this study also reports the existence of a gender gap in business related experience amongst SMME owners. However, after controlling for business related experience, the gender gap in SMMEs access to venture capital and performance disappears. This study therefore argues that the variation in business related experience between gender plays a major role in the noted gender gap. This study therefore concludes that addressing gender gap in business related experience is of vital importance as this would also assist in eliminating the apparent gender gap in access to venture capital and firm performance. To address the gender gap in business related experience, the study recommends that innovations in the design and delivery of training programmes should be implemented. Establishing and monitoring targets for current women managers who are also potential future business owners/SMME owners, should be a policy being practiced in both the private and public sector, among other recommendations outlined in the study.
- Full Text:
- Date Issued: 2014
- Authors: Shava, Herring
- Date: 2014
- Subjects: Small business -- South Africa -- Eastern Cape , Venture capital -- South Africa -- Eastern Cape , Entrepreneurship -- South Africa -- Eastern Cape , Sex discrimination -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , M Com (Business Management)
- Identifier: http://hdl.handle.net/10353/767 , vital:26495 , Small business -- South Africa -- Eastern Cape , Venture capital -- South Africa -- Eastern Cape , Entrepreneurship -- South Africa -- Eastern Cape , Sex discrimination -- South Africa -- Eastern Cape
- Description: This study examined the influence of gender on access to venture capital and firm performance on Small, Medium and Micro Enterprises in King Williams Town, South Africa. This study sought to establish whether there was differential access to venture capital between genders; to establish whether men- and women-owned SMMEs differ in performance; to identify whether an association between gender and business related experience can be found; and to assess the extent to which the gender gap in SMME access to venture capital and performance could be allocated to gender differences in levels of business related experience. A total sample of 109 SMMEs was used which comprised 53 female- and 56 male-owned. The quota sampling technique was implemented and a self-administered questionnaire was used for the purpose of gathering primary data. Data for this study was gathered from SMME owners only as they were the targeted respondents. The t-test and Chi-square test were used for the statistical analysis in order to arrive at findings and conclusions. Based on a 64% survey response rate, the study reports the existence of statistically significant gender gap in SMME access to venture capital and SMME performance. In addition, this study also reports the existence of a gender gap in business related experience amongst SMME owners. However, after controlling for business related experience, the gender gap in SMMEs access to venture capital and performance disappears. This study therefore argues that the variation in business related experience between gender plays a major role in the noted gender gap. This study therefore concludes that addressing gender gap in business related experience is of vital importance as this would also assist in eliminating the apparent gender gap in access to venture capital and firm performance. To address the gender gap in business related experience, the study recommends that innovations in the design and delivery of training programmes should be implemented. Establishing and monitoring targets for current women managers who are also potential future business owners/SMME owners, should be a policy being practiced in both the private and public sector, among other recommendations outlined in the study.
- Full Text:
- Date Issued: 2014
Towards a framework for enhancing user trust in cloud computing
- Authors: Nyoni, Tamsanqa B
- Date: 2014
- Subjects: Adoption -- Cloud Computing , User Trust
- Language: English
- Type: Thesis , Masters , MCom (Information Systems)
- Identifier: vital:11142 , http://hdl.handle.net/10353/d1014674 , Adoption -- Cloud Computing , User Trust
- Description: Cloud computing is one of the latest appealing technological trends to emerge in the Information Technology (IT) industry. However, despite the surge in activity and interest, there are significant and persistent concerns about cloud computing, particularly with regard to trusting the platform in terms of confidentiality, integrity and availability of user data stored through these applications. These factors are significant in determining trust in cloud computing and thus provide the foundation for this study. The significant role that trust plays in the use of cloud computing was considered in relation to various trust models, theories and frameworks. Cloud computing is still considered to be a new technology in the business world, therefore minimal work and academic research has been done on enhancing trust in cloud computing. Academic research which focuses on the adoption of cloud computing and, in particular, the building of user trust has been minimal. The available trust models, frameworks and cloud computing adoption strategies that exist mainly focus on cost reduction and the various benefits that are associated with migrating to a cloud computing platform. Available work on cloud computing does not provide clear guidelines for establishing user trust in a cloud computing application. The issue of establishing a reliable trust context for data and security within cloud computing is, up to this point, not well defined. This study investigates the impact that a lack of user trust has on the use of cloud computing. Strategies for enhancing user trust in cloud computing are required to overcome the data security concerns. This study focused on establishing methods to enhance user trust in cloud computing applications through the theoretical contributions of the Proposed Trust Model by Mayer, Davis, and Schoorman (1995) and the Confidentiality, Integrity, Availability (CIA) Triad by Steichen (2010). A questionnaire was used as a means of gathering data on trust-related perceptions of the use of cloud computing. The findings of this questionnaire administered to users and potential users of cloud computing applications are reported in this study. The questionnaire primarily investigates key concerns which result in self-moderation of cloud computing use and factors which would improve trust in cloud computing. Additionally, results relating to user awareness of potential confidentiality, integrity and availability risks are described. An initial cloud computing adoption model was proposed based on a content analysis of existing cloud computing literature. This initial model, empirically tested through the questionnaire, was an important foundation for the establishment of the Critical Success Factors (CSFs) and therefore the framework to enhance user trust in cloud computing applications. The framework proposed by this study aims to assist new cloud computing users to determine the appropriateness of a cloud computing service, thereby enhancing their trust in cloud computing applications.
- Full Text:
- Date Issued: 2014
- Authors: Nyoni, Tamsanqa B
- Date: 2014
- Subjects: Adoption -- Cloud Computing , User Trust
- Language: English
- Type: Thesis , Masters , MCom (Information Systems)
- Identifier: vital:11142 , http://hdl.handle.net/10353/d1014674 , Adoption -- Cloud Computing , User Trust
- Description: Cloud computing is one of the latest appealing technological trends to emerge in the Information Technology (IT) industry. However, despite the surge in activity and interest, there are significant and persistent concerns about cloud computing, particularly with regard to trusting the platform in terms of confidentiality, integrity and availability of user data stored through these applications. These factors are significant in determining trust in cloud computing and thus provide the foundation for this study. The significant role that trust plays in the use of cloud computing was considered in relation to various trust models, theories and frameworks. Cloud computing is still considered to be a new technology in the business world, therefore minimal work and academic research has been done on enhancing trust in cloud computing. Academic research which focuses on the adoption of cloud computing and, in particular, the building of user trust has been minimal. The available trust models, frameworks and cloud computing adoption strategies that exist mainly focus on cost reduction and the various benefits that are associated with migrating to a cloud computing platform. Available work on cloud computing does not provide clear guidelines for establishing user trust in a cloud computing application. The issue of establishing a reliable trust context for data and security within cloud computing is, up to this point, not well defined. This study investigates the impact that a lack of user trust has on the use of cloud computing. Strategies for enhancing user trust in cloud computing are required to overcome the data security concerns. This study focused on establishing methods to enhance user trust in cloud computing applications through the theoretical contributions of the Proposed Trust Model by Mayer, Davis, and Schoorman (1995) and the Confidentiality, Integrity, Availability (CIA) Triad by Steichen (2010). A questionnaire was used as a means of gathering data on trust-related perceptions of the use of cloud computing. The findings of this questionnaire administered to users and potential users of cloud computing applications are reported in this study. The questionnaire primarily investigates key concerns which result in self-moderation of cloud computing use and factors which would improve trust in cloud computing. Additionally, results relating to user awareness of potential confidentiality, integrity and availability risks are described. An initial cloud computing adoption model was proposed based on a content analysis of existing cloud computing literature. This initial model, empirically tested through the questionnaire, was an important foundation for the establishment of the Critical Success Factors (CSFs) and therefore the framework to enhance user trust in cloud computing applications. The framework proposed by this study aims to assist new cloud computing users to determine the appropriateness of a cloud computing service, thereby enhancing their trust in cloud computing applications.
- Full Text:
- Date Issued: 2014
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