The psycho-social functioning and experiences of children in child-headed households in Gauteng Province, South Africa
- Authors: Agere, Leonard Munyaradzi
- Date: 2018
- Subjects: Adult children -- South Africa -- Conduct of life , Youth-headed households -- South Africa , Child support -- South Africa
- Language: English
- Type: Thesis , Doctoral , Social Work
- Identifier: http://hdl.handle.net/10353/10646 , vital:35651
- Description: The study was aimed at investigating the psycho-social needs and lived experiences of child headed households in the Gauteng Province of South Africa. A mixed methods approach was used to collect and analyse the data. The qualitative approach was the dominant one, while a quantitative approach was used to corroborate the qualitative findings. The quantitative data was collected through a survey. Three hundred questionnaires were distributed among children in child headed households. The child headed households were selected through simple random sampling from the databases of the NGOs and community based organisations that had agreed to participate in the study. The quantitative component of the study produced results that supported the qualitative findings. The qualitative data was collected through in-depth interviews and focus group discussions, which were conducted with purposively selected social service practitioners and community structures who were involved in work with child headed households. The resilience approach, which posits that humans are born with inherent reserves to face adversity, and the ecological systems theory, which postulates the framework in which an individual can be understood in his constant interactions and relationships within community and wider society, inform this study. The findings of the study indicate that there were various psycho social needs and challenges that child headed households faced. As Maslow postulated in his hierarchy of needs theory, inferences were made to the diverse needs of the child headed households. Physiological needs like food, clothing and finance were found to be more presenting and eminent needs for the child headed households. The study findings highlighted safety needs in the form of need for formal housing as the majority lived in informal settlements where they were exposed to much vulnerability like violence, sexual exploitation and other social misdemeanours. Other needs were esteem and familial needs, which provided a platform to foster senses of identity and belonging. However, there were other child headed households who were fortunate to have extended family members and community based organisations that assisted by providing these needs and these gestures were appreciated by the households as they ameliorated dire situations and cushioned them from absolute poverty. The findings further revealed that the psycho social challenges and needs did not only present when the household became child headed household but when their parent/s was still with them and were only exacerbated in their absence. The effects of living with parental illness, sadness and anxiety due to dramatic changes in dynamics, pain and trauma witnessing a parent dying were among the psychosocial challenges faced when the parent was still present with the children. After their departure or absence the challenges shifted and the debilitating effects of grief and loss, emotional trauma, living without adult caregiver and stigma and discrimination, were among the cocktail of challenges that the child headed households faced. However, others had support from extended family members and community structures that supported them with palliative care for the terminally ill and this afforded them the much needed respite as they focused on their studies and enjoyed their rights to be children. The study reveals that children have several coping mechanisms that exude their resilience and this includes support from social workers in promoting sustainable development goals (SDG’s) including no poverty, good health and well-being and quality education (goals 1, 3 and 4). The study highlighted that others had to supplement education with paid work (informal) whilst some ended up disengaging from their education to pursue paid employment to eke a living and support their siblings. The community and NGO’s were seen as vital components of the ecosystem that promoted the resilience of the child headed households in coping with their day to day challenges and needs. On the basis of the findings, it is recommended that the South African government should, among other things, provide a properly resourced, co-ordinated and well managed child protection system to facilitate constituency work that responds to the real needs of child headed households and SMART planning by social workers, with systemic teaming around CHH with the DSD as lead agency. The study also recommends a psychosocial approach to CHH care in the form of a model that rallies for robust assessments that social service practitioners and every structure that has the “duty to care” for CHH, can embed in their practice for improved outcomes.
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- Date Issued: 2018
Biochemical mechanisms towards understanding Alzheimer's disease
- Authors: Padayachee, Eden Rebecca
- Date: 2014
- Subjects: Alzheimer's disease Nitric-oxide synthase Biochemical markers Amyloid beta-protein Peptide hormones
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:4103 , http://hdl.handle.net/10962/d1011092
- Description: The start of the amyloidogenic pathway in Alzheimer’s disease (AD) begins with the deposition of the Aβ₁₋₄₂ peptide surrounded by astrocytes. High levels of arginine and low amounts of neuronal nitric oxide synthase (nNOS) are associated with AD. These astrocytes store reserve arginine that is eventually metabolized by nNOS, within the vicinity of the Aβ₁₋₄₂ peptide. We propose the existence of an association vs. dissociation equilibrium between Aβ and nNOS such that nNOS is an amyloidogenic catalyst for fibrils. When Aβ binds to nNOS, it inhibits the activity of the enzyme (association phase). However when the amyloid peptide dissociates into a form that can no longer bind, later deduced as a fibril, the activity is restored. Thus, the interaction of Aβ with nNOS could serve to regulate the interaction between nNOS and arginine by restoring activity of the enzyme but at the same time promoting fibrillogenesis. Given this event occurring with the neuron, both nNOS and amyloid can serve as a biomarker for the early onset of AD. The enzyme nNOS catalyzed the formation of fibrils in the presence of Aβ peptides, while Ag nps were shown to reverse the fibril formation from Aβ peptides more so than Au and curcumin either through electrostatic or π-π stacking (aromatic) influences. Our studies have shown that the fragments of Aβ₁₋₄₂ i.e. the pentapeptide (Aβ₁₇₋₂₁) and the three glycine zipper peptides (Aβ₂₅₋₂₉, Aβ₂₉₋₃₃, Aβ₃₃₋₃₇) and the full length glycine zipper stretch (Aβ₂₅₋₃₇) all inhibited nNOS activity to varying degrees. The peptides Aβ₁₇₋₂₁ and Aβ₂₉₋₃₃ with their respective Ki values of 5.1 μM and 7.5 μM inhibited the enzyme the most. The Ki values for reversed sequenced peptides (Aβ₁₇₋₂₁r and Aβ₂₉₋₃₃r) were two fold greater than that of the original peptides while the Ki values for the polar forms (Aβ₁₇₋₂₁p and Aβ₂₉₋₃₃p) were between 3-4 fold greater than that of the original peptides. It was also found that Ag nps (Ki = 0.12 μM) inhibited the activity of nNOS the most compared to Au nps; (Ki = 0.15 μM) and curcumin (Ki = 0.25 μM). At 298K, all the ligands bound at a single site on the enzyme (n=1) and a single Trp residue (θ =1), (later identified as Trp678) was made available on the enzyme surface for quenching by the ligands. Increasing the temperature from 298K-313K, increased the value of Ksv and pointed to a dynamic quenching mechanism for Aβ peptides, nps and curcumin interaction with nNOS. The positive signs for entropy and enthalpy for all Aβ peptides nps and curcumin pointed to hydrophobic–hydrophobic interaction with the enzyme. The fact that Kd increased with temperature emphasized the endothermic nature of the binding reaction and the requirement of thermal energy to aid in diffusion of the ligand to the active site. It was concluded that the binding reaction between the ligands and nNOS was non-spontaneous and endothermic at low temperatures (+ΔG) but spontaneous at high temperatures (-ΔG). The two amino acids Tyr706 and Trp678 moved from their original positions, subject to ligand binding. Trp678 moved a minimum distance of 5 Å toward the heme while Tyr706 moved a maximum distance of 14 Å away from the heme. AutoDock 4.2 was a valuable tool in monitoring the distance of Trp678 within the enzyme interior and fluorescence resonance energy transfer (FRET) was efficient in monitoring the distance moved by Trp residues on the enzyme surface.
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- Date Issued: 2014
Green zone nation : the securitisation and militarisation of the 2010 FIFA World Cup, South Africa
- Authors: McMichael, Christopher Bryden
- Date: 2013 , 2013-04-22
- Subjects: World Cup (Soccer) (2010 : South Africa) -- Safety measures -- Research Fédération internationale de football association Militarism -- Research -- South Africa Sports -- Political aspects -- Research -- South Africa Police -- South Africa South Africa -- Armed Forces Crime -- South Africa Violent crimes -- South Africa Violent crimes -- South Africa
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:2752 , http://hdl.handle.net/10962/d1001622
- Description: This thesis explores the relationship between the safety and security measures for the 2010 FIFA World Cup and the militarisation of urban space and policing in post-apartheid South Africa. In particular, it focuses upon how the South African state and FIFA, the owners of the World Cup franchise, worked to present the World Cup as an event which required exceptional levels of security – resulting in a historically unprecedented joint police and military operation across host cities. However, in contrast with previous research on these security measures, this thesis aims to interrogate the political and commercial forces which constructed security and positions them against a backdrop of intensified state violence and social exclusion in South Africa. Concurrently, the South African case was indicative of an international militarisation of major events, with policing operations comparable to national states of emergency. This is representative of the ‘new military urbanism’ in which everyday urban life is rendered as a site of ubiquitous risk, leading to the increased diffusion of military tactics and doctrines in policing and policy. While the interpenetration between urbanism and militarism has often been studied against the context of the ‘war on terror’, in the case of South Africa this has primarily been accelerated by a pervasive social fear of violent crime, which has resulted in the securitisation of cities, the remilitarisation of policing and the intensification of a historical legacy of socio-spatial inequalities. The South African government aimed to use the World Cup to ‘rebrand’ the country’s violent international image, while promising that security measures would leave a legacy of safer cities for ordinary South Africans. The concept of legacies was also responsive to the commercial imperatives of FIFA and a range of other security actors, including foreign governments and the private security industry. However these policing measures were primarily cosmetic and designed to allay the fears of foreign tourists and the national middle class. In practice security measures pivoted around the enforcement of social control and urban marginalisation while serving as a training ground for an increasingly repressive state security apparatus. Security was as much a matter of fortifying islands of privilege and aiding a project of financial extraction as protecting the public from harm. , Microsoft� Office Word 2007 , Adobe Acrobat 9.53 Paper Capture Plug-in
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- Date Issued: 2013
My other - my self: post-Cartesian ontological possibilities in the fiction of J M Coetzee
- Authors: Mfune, Damazio Laston
- Date: 2011
- Subjects: Coetzee, J. M., 1940- -- Criticism and interpretation Self in literature Identity (Psychology) in literature Consciousness in literature Intersubjectivity in literature Ontology in literature Metaphysics in literature South African fiction (English) -- 20th century -- History and criticism
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:2246 , http://hdl.handle.net/10962/d1002289
- Description: The central argument of my study is that, among other matters, in his works, J.M. Coetzee could be said to demonstrate that the known Self is an embodied being and is not autonomous. With regard to the latter contention, Coetzee intimates that any two Subjects are implicated in each other’s subjectivities in a reciprocal process that involves what Derek Attridge has called “irruptions of otherness” (2005: xii) into the Subject’s subjectivity. These irruptions, which happen during the encounter, lead to a double loss of autonomy for each Subject and this phenomenon renders the relationship between Subjects non-dichotomus or non-binaric. In other words, the Subject does not produce the contents of his or her consciousness in a sui generis and ex nihilo fashion, and his or her ontological indebtedness to the Other constitutes his or her first loss of autonomy. As for those Others that do possess consciousness, the Subject is implicated in their consciousness and this constitutes the Subject’s second loss of autonomy. These losses counter the near solipsistic Nagelian neo-Cartesianism and paves the way for imagining both intra- and inter-species “intersubjectivity”. It is my view that this double loss of autonomy accounts for the sympathetic and empathetic imagination that we encounter in Coetzee’s fiction. Following Coetzee’s intimations of intersubjectivity through irruptions of otherness, what I see as my contribution to studies on this author’s work through this study is the link I have established between the physicalist strain within the philosophy of mind (whose central thesis is that consciousness is an embodied phenomenon) and a modified Kantian “metaphysics”, especially Immanuel Kant’s conception of concepts as comprising form and content. I have deployed this conception in demonstrating the Subject’s ontological indebtedness to external sources of the content part of consciousness. And, through the Husserlian concept of intentionality, and Kant’s (1929: 27) observation that we cannot have appearances without something that appears, I have linked the Subject to the sources of his or her content and thereby also demonstrated that the Subject is not eternally separated or alienated from those sources. Instead, the Subject is not simply contiguous but coterminous and co-extensive, albeit in a mediated way, with the external sources of the content part of his or her consciousness. Thus, while accepting the thesis of the Other’s radical otherness, I modify the thesis of the Other’s radical exteriority. Ultimately, then, ontologically speaking, the Coetzeean project could be described as one of embodying and grounding the supposedly autonomous, solipsistic and freefloating/disembodied Cartesian Subject. This he does by alerting this Subject, first and foremost, to its embodiedness and, further to that, pointing out its ontological indebtedness to its Others and its implication in the Others’s consciousnesses and so prevent it from continuing with its imperialistic and ecological barbarities. However, ethically speaking, beyond the reciprocal ethics that arises from mutual ontological indebtedness and implication, it is the selflessness that characterises a cruciform logic that comes across as the epitome of Coetzeean ethics.
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- Date Issued: 2011
'Environmental policy to community action': methodology and approaches in community-based environmental education programmes in Uganda
- Authors: Babikwa, Daniel J
- Date: 2004
- Subjects: Environmental education -- Uganda -- Case studies Education and state -- Uganda Community development -- Uganda -- Case studies Sustainable development -- Uganda -- Case studies Environmental policy -- Uganda -- Case studies
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:1518 , http://hdl.handle.net/10962/d1003400
- Description: This research was conducted in Luwero, a rural district in central Uganda, over a period of three years, half of which entailed fulltime engagement in a participatory action research process with VEDCO, an indigenous NGO. The study focuses on the educational processes involved in the translation of Uganda's environmental policy into action at community level. It looks at community-based education and development activities run by VEDCO among smallholder farmers. The study addressed four objectives. For the first objective I developed a conceptual framework through a review of theories informing education in general and environmental education, adult education, community education, and community development in particular. The second objective was to conduct a situational analysis to identify contextual issues related to policy implementation at community level. The third objective was to engage in a participatory action research process with the NGO in the farming community in response to the identified contextual issues, and the fourth was to explore and comment on environmental education methods used within a community context. PRA techniques, interviews, and other participatory data collection methods were used to generate the data. The study reveals contradictions that limit NGO capacity to make appropriate use of participatory education processes in implementing policy-related training at community level. Elements in the National Plan for the Modernisation of Agriculture, for example, conflicted with the principle of sustainable development underlying the policy. VEDCO itself was changing from a social-welfare-oriented organisation into a commercial enterprise pursuing economic goals, which conflicted with its social goals. The capitalist development ideology of the donor was being adopted by VEDCO, which contradicted the goals of people-centred development. This was exacerbated by VEDCO's dependency on donor funds for its activities. Contextual issues like people's history; poverty, gender and inconsistent land policies further complicated the policy implementation processes. There were also inconsistencies in the epistemological assumptions and didactic approaches evident in the implementation. The study shows that the intended emancipatory education processes are more often supplanted by technicist methodologies. Thus, it exposes the underlying historical, ideological and epistemological tensions and contradictions within the field of education, particularly in relation to the `paradigmatic' orientations (neo-classical, liberal and socially critical/emancipatory) outlined in the literature. Conclusions are made at two levels: in relation to the study goals, of examining policy implementation at community level and in terms of the study's contribution to the understanding of current education theory in the context of sustainable development among communities.
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- Date Issued: 2004
A comparative study of atmospheric dynamics in the mesosphere and lower thermosphere (MLT) near Grahamstown (South Africa) and Adelaide (Australia)
- Authors: Malinga, Sandile Bethuel
- Date: 2002
- Subjects: Atmospheric physics Atmospheric physics -- South Africa -- Eastern Cape Atmospheric physics -- Australia Dynamic meteorology
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: vital:5506 , http://hdl.handle.net/10962/d1007307
- Description: The observations made near Grahamstown (33 .3°S, 26.5°E), South Africa and Adelaide (34.5°S, 138.5°E), Australia over the years 1987 to 1994 are used to study the dynamics of the mesosphere and lower thermosphere (ML T) region with a focus on ∼ 90 km altitude. In particular this thesis deals with on the atmospheric mean flow and the solar diurnal and semi diurnal oscillations with a view to (i) deducing their patterns at the two sites, (ii) comparing the dynamic structures observed at the two sites with special emphases on longitudinal variations, and (iii) putting these observations in a global context by comparing with other ground-based observations, satellite observations and numerical simulations. The main findings are summarised below. The mean flow and the tides at Grahamstown and Adelaide are characteristically variable at planetary time scales. Wavelet spectral and multiresolution analyses reveal that the dominant planetary oscillation is the quasi-16-day oscillation. However, no apparent correlation in the 16-day waves of the mean flow, the diurnal tide and the semidiurnal tide was found. The short-term fluctuations were also investigated using complex demodulation and bispectral techniques and it was found that some of the observed variations in tides could be due to non-linear wave-wave interactions. The long-term trends of the mean flow and tides show patterns that are in broad agreement with theory, results from elsewhere (ground-based and satellite) and the results of the Global-Scale Wave Model and various models by Portnyagin and others. In general the mean flow, the amplitudes and phases of both tides were found to exhibit seasonal and interannual variations which are thought to be related to various factors including (i) changes in the atmospheric mean environment, (ii) thermotidal forcing (iii) gravity wave effects, (iv) planetary scale influence, (v) long-term (e.g. quasi-biennial oscillation) modulation, and (vi) solar activity. There are significant longitudinal differences in the dynamic structure between Grahamstown and Adelaide. More especially, Grahamstown tends to have stronger mean flow and tidal activity than Adelaide. For tides, these differences are thought to be partly due to nonmigrating tidal modes but, in general, migrating modes were found to be dominant.
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- Date Issued: 2002