Rebellion and revolution
- Authors: Tabensky, Pedro
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/305721 , vital:58606 , xlink:href="https://doi.org/10.1080/0969725X.2019.1574085"
- Description: In this piece I will focus on what I think is a central aspect of Albert Camus’s thinking, embodied in the distinction he makes in The Rebel between rebel and revolutionary. His is a philosophy of rebellion and he thinks that revolutions are a distorted expression of our need to rebel against that which we cannot accept. His views should serve as a counterpoint to those who think that an all-or-nothing approach to social change is desirable (those who, for instance, are too quick to justify murderous campaigns allegedly aimed at justice). And the issue here is not that embodied crudely in the reactionary (or conservative)/radical dichotomy. Rather, it is a defence of the need to rebel within limits, not so much to preserve the old against the threat of the new but, instead, to preserve basic human decency from the dark side of outrage, without dismissing what is crucial about outrage and emancipatory struggles.
- Full Text:
- Date Issued: 2019
- Authors: Tabensky, Pedro
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/305721 , vital:58606 , xlink:href="https://doi.org/10.1080/0969725X.2019.1574085"
- Description: In this piece I will focus on what I think is a central aspect of Albert Camus’s thinking, embodied in the distinction he makes in The Rebel between rebel and revolutionary. His is a philosophy of rebellion and he thinks that revolutions are a distorted expression of our need to rebel against that which we cannot accept. His views should serve as a counterpoint to those who think that an all-or-nothing approach to social change is desirable (those who, for instance, are too quick to justify murderous campaigns allegedly aimed at justice). And the issue here is not that embodied crudely in the reactionary (or conservative)/radical dichotomy. Rather, it is a defence of the need to rebel within limits, not so much to preserve the old against the threat of the new but, instead, to preserve basic human decency from the dark side of outrage, without dismissing what is crucial about outrage and emancipatory struggles.
- Full Text:
- Date Issued: 2019
Reconfiguring the Omweso board game: performing narratives of Buganda material culture
- Authors: Kirumira, Rose Namubiru
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/145996 , vital:38487 , https://0-doi.org.wam.seals.ac.za/10.1162/afar_a_00460
- Description: My artwork titled Nakulabye, which is 4 meters long and weighs 440 pounds, is an intimidating sculptural replica of the Omweso game board (Fig. 1). The wooden sculpture, twenty times larger than an average Omweso game board, includes four cane stools to sit on during play. Its composition is derived from a human face, and it has thirty-two pits (8 × 4) in the configuration of a mancala board. This sculpture was inspired by my engagement with a group of men that I visited in July 2016 in Nakulabye, a town in an urban area of Kampala City, Uganda. At the Nakulabye Omweso Club, a shop veranda in Nakulabye Town, these men play Omweso and chat against the backdrop of a small television that mostly screens British Premiere Leagues. Observing their exchanges, which seem to be informed by moves on the Omweso board and reveal strong, clearly gendered power dynamics, I became curious about the performative place of Omweso as a cultural artifact of the Baganda people.
- Full Text:
- Date Issued: 2019
- Authors: Kirumira, Rose Namubiru
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/145996 , vital:38487 , https://0-doi.org.wam.seals.ac.za/10.1162/afar_a_00460
- Description: My artwork titled Nakulabye, which is 4 meters long and weighs 440 pounds, is an intimidating sculptural replica of the Omweso game board (Fig. 1). The wooden sculpture, twenty times larger than an average Omweso game board, includes four cane stools to sit on during play. Its composition is derived from a human face, and it has thirty-two pits (8 × 4) in the configuration of a mancala board. This sculpture was inspired by my engagement with a group of men that I visited in July 2016 in Nakulabye, a town in an urban area of Kampala City, Uganda. At the Nakulabye Omweso Club, a shop veranda in Nakulabye Town, these men play Omweso and chat against the backdrop of a small television that mostly screens British Premiere Leagues. Observing their exchanges, which seem to be informed by moves on the Omweso board and reveal strong, clearly gendered power dynamics, I became curious about the performative place of Omweso as a cultural artifact of the Baganda people.
- Full Text:
- Date Issued: 2019
Remedies, repentance and the doctrine of election in South African contract law
- Authors: Glover, Graham B
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/186712 , vital:44527 , xlink:href="https://hdl.handle.net/10520/EJC-1a756528b2"
- Description: One of the main features of South Africa’s law on remedies for breach of contract is the doctrine of election. In cases where a major breach has occurred, or a cancellation clause entitles the aggrieved party to seek cancellation, the aggrieved party has an election either to cancel or to claim performance, and will be held to that binary choice. In Primat Construction CC v Nelson Mandela Bay Metropolitan Municipality the Supreme Court of Appeal recently recognised an exception to the usual election rule, specifically in cases involving repudiation. In terms of the ‘repentance principle’, a party who experiences repudiation may initially seek performance in the hope that the breaching party will repent of their breach; but if it does not, the aggrieved party may then change its mind and seek cancellation. This essay considers the history of the doctrine of election and the path to the recognition of its qualifier, the repentance principle. Thereafter, the essay poses the question whether it remains desirable for the strict doctrine of election to continue to apply in South African law, bearing in mind that a strict election can have an unduly constraining effect on the interests of the non-breaching (or ‘innocent’) party. This analysis is informed by the broader policy considerations behind the recognition of the repentance principle; the fact that other analogous exceptions to the election rule do exist; and the fact that other jurisdictions do not adopt such a strict approach to the aggrieved party’s choice of remedy.
- Full Text:
- Date Issued: 2019
- Authors: Glover, Graham B
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/186712 , vital:44527 , xlink:href="https://hdl.handle.net/10520/EJC-1a756528b2"
- Description: One of the main features of South Africa’s law on remedies for breach of contract is the doctrine of election. In cases where a major breach has occurred, or a cancellation clause entitles the aggrieved party to seek cancellation, the aggrieved party has an election either to cancel or to claim performance, and will be held to that binary choice. In Primat Construction CC v Nelson Mandela Bay Metropolitan Municipality the Supreme Court of Appeal recently recognised an exception to the usual election rule, specifically in cases involving repudiation. In terms of the ‘repentance principle’, a party who experiences repudiation may initially seek performance in the hope that the breaching party will repent of their breach; but if it does not, the aggrieved party may then change its mind and seek cancellation. This essay considers the history of the doctrine of election and the path to the recognition of its qualifier, the repentance principle. Thereafter, the essay poses the question whether it remains desirable for the strict doctrine of election to continue to apply in South African law, bearing in mind that a strict election can have an unduly constraining effect on the interests of the non-breaching (or ‘innocent’) party. This analysis is informed by the broader policy considerations behind the recognition of the repentance principle; the fact that other analogous exceptions to the election rule do exist; and the fact that other jurisdictions do not adopt such a strict approach to the aggrieved party’s choice of remedy.
- Full Text:
- Date Issued: 2019
Research for the people, by the people: The political practice of cognitive justice and transformative learning in environmental social movements
- Authors: Burt, Jane C
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/392177 , vital:68728 , xlink:href="https://doi.org/10.3390/su11205611"
- Description: This paper describes how Changing Practice courses, developed by environmental activists in South Africa and based on social learning practice, have seeded cognitive justice action. For the educator-activists who facilitated these courses, it became apparent that we needed a bold emancipatory pedagogy which included cognitive justice issues. This enabled us and the activist-researcher participants to understand the extent to which local, indigenous, and spiritual knowledge had been excluded from water governance. The paper investigates how participants in the ‘Water and Tradition’ change project, established by the Vaal Environmental Justice Alliance (VEJA, engaged with cognitive justice, to demonstrate how African spiritual practice offers a re-visioning of the natural world. Finally, using the tools of critical realist theory, the paper reviews how VEJA bring about transformative social action through their participation in the Changing Practice course.
- Full Text:
- Date Issued: 2019
- Authors: Burt, Jane C
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/392177 , vital:68728 , xlink:href="https://doi.org/10.3390/su11205611"
- Description: This paper describes how Changing Practice courses, developed by environmental activists in South Africa and based on social learning practice, have seeded cognitive justice action. For the educator-activists who facilitated these courses, it became apparent that we needed a bold emancipatory pedagogy which included cognitive justice issues. This enabled us and the activist-researcher participants to understand the extent to which local, indigenous, and spiritual knowledge had been excluded from water governance. The paper investigates how participants in the ‘Water and Tradition’ change project, established by the Vaal Environmental Justice Alliance (VEJA, engaged with cognitive justice, to demonstrate how African spiritual practice offers a re-visioning of the natural world. Finally, using the tools of critical realist theory, the paper reviews how VEJA bring about transformative social action through their participation in the Changing Practice course.
- Full Text:
- Date Issued: 2019
Rethinking the dialectics of rural and urban in African art and scholarship:
- Siegenthaler, Fiona, Nzewi, Ugochukwu-Smooth C, Siegert, Nadine
- Authors: Siegenthaler, Fiona , Nzewi, Ugochukwu-Smooth C , Siegert, Nadine
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/146022 , vital:38488 , DOI: 10.1080/19301944.2018.1538856
- Description: This issue of Critical Interventions is dedicated to rethinking the dialectics of the rural and the urban in African art and scholarship. Inspired by the general theme of the European Conference of African Studies (ECAS/AEGIS) in Basel (June 28 to July 1, 2017), Urban Africa – Urban Africans: New Encounters of the Rural and the Urban, the guest editors of this issue hosted two panels on the relationship of urban-based artists and their interest in rural topographies, aesthetics, and cultural practices.
- Full Text:
- Date Issued: 2019
- Authors: Siegenthaler, Fiona , Nzewi, Ugochukwu-Smooth C , Siegert, Nadine
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/146022 , vital:38488 , DOI: 10.1080/19301944.2018.1538856
- Description: This issue of Critical Interventions is dedicated to rethinking the dialectics of the rural and the urban in African art and scholarship. Inspired by the general theme of the European Conference of African Studies (ECAS/AEGIS) in Basel (June 28 to July 1, 2017), Urban Africa – Urban Africans: New Encounters of the Rural and the Urban, the guest editors of this issue hosted two panels on the relationship of urban-based artists and their interest in rural topographies, aesthetics, and cultural practices.
- Full Text:
- Date Issued: 2019
Risk assessment to interpret the physiological host range of Hydrellia egeriae, a biocontrol agent for Egeria densa
- Smith, Rosalie, Mangan, Rosie, Coetzee, Julie A
- Authors: Smith, Rosalie , Mangan, Rosie , Coetzee, Julie A
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/418053 , vital:71504 , xlink:href="https://doi.org/10.1007/s10526-019-09942-4"
- Description: Egeria densa Planchon (Hydrocharitaceae) is a submerged macrophyte native to South America. It forms part of a new suite of invasive aquatic plants that has benefited from open nutrient-rich freshwater systems following the successful biological control of floating aquatic plants in South Africa. The specificity of the leaf-mining fly, Hydrellia egeriae Rodrigues (Diptera: Ephydridae) was tested, using traditional laboratory host-specificity testing (i.e., no-choice and paired choice). Only one non-target species, Lagarosiphon major Deeming (Hydrocharitaceae) supported larval development during pair-choice tests. In order to avoid the rejection of a safe and potentially effective agent, continuation (i.e., multiple generations) tests were conducted to measure the ability of the non-target species to nutritionally support a population indefinitely. None of these species could sustain a viable agent population for more than three generations. Laboratory host-specificity tests are limited as they exempt certain insect-host behaviours. To enhance the interpretation of host-specificity results, a risk assessment was conducted using agent preference (i.e., choice tests) and performance (i.e., choice and continuation tests) results. The feeding and reproductive risk that H. egeriae poses to non-target species is below 2%. Based on these findings, permission for its release in South Africa has been obtained.
- Full Text:
- Date Issued: 2019
- Authors: Smith, Rosalie , Mangan, Rosie , Coetzee, Julie A
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/418053 , vital:71504 , xlink:href="https://doi.org/10.1007/s10526-019-09942-4"
- Description: Egeria densa Planchon (Hydrocharitaceae) is a submerged macrophyte native to South America. It forms part of a new suite of invasive aquatic plants that has benefited from open nutrient-rich freshwater systems following the successful biological control of floating aquatic plants in South Africa. The specificity of the leaf-mining fly, Hydrellia egeriae Rodrigues (Diptera: Ephydridae) was tested, using traditional laboratory host-specificity testing (i.e., no-choice and paired choice). Only one non-target species, Lagarosiphon major Deeming (Hydrocharitaceae) supported larval development during pair-choice tests. In order to avoid the rejection of a safe and potentially effective agent, continuation (i.e., multiple generations) tests were conducted to measure the ability of the non-target species to nutritionally support a population indefinitely. None of these species could sustain a viable agent population for more than three generations. Laboratory host-specificity tests are limited as they exempt certain insect-host behaviours. To enhance the interpretation of host-specificity results, a risk assessment was conducted using agent preference (i.e., choice tests) and performance (i.e., choice and continuation tests) results. The feeding and reproductive risk that H. egeriae poses to non-target species is below 2%. Based on these findings, permission for its release in South Africa has been obtained.
- Full Text:
- Date Issued: 2019
Science in the service of society: Is marine and coastal science addressing South Africa's needs?
- Cochrane, Kevern L, Sauer, Warwick H H, Aswani, Shankar
- Authors: Cochrane, Kevern L , Sauer, Warwick H H , Aswani, Shankar
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/126071 , vital:35847 , https://doi.10.17159/sajs.2019/4418
- Description: The modern world is confronted with many and diverse social and environmental challenges of high complexity. In South Africa, rapid and sustainable development is needed to address high levels of poverty and unemployment but this development has to take place in the context of an environment that is already severely impacted by human activities. Sound and relevant scientific input and advice, covering the full scope of each challenge, is essential for effective decisions and actions to address the needs. South Africa has the benefit of strong scientific capacity but the country’s National Development Plan reported that national research priorities were not always consistent with South Africa’s needs. We investigate the validity of that conclusion in the coastal and marine sciences by examining presentations made at the 2017 South African Marine Science Symposium on the theme of ‘Unlocking the ocean’s economic potential whilst maintaining social and ecological resilience’. Despite the theme, only 21% of the presentations were judged to be actionable and directly relevant to societal needs, as defined by the criteria used. Less than 7% were evaluated as being interdisciplinary within the natural sciences and approximately 10% were found to include both natural and human sciences. Poor representation by the human sciences was also noteworthy. This preliminary assessment highlights the need for an urgent review of the disciplinary representation and approaches in marine and coastal science in South Africa in the context of the priority practical needs of the country now and into the future.
- Full Text:
- Date Issued: 2019
- Authors: Cochrane, Kevern L , Sauer, Warwick H H , Aswani, Shankar
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/126071 , vital:35847 , https://doi.10.17159/sajs.2019/4418
- Description: The modern world is confronted with many and diverse social and environmental challenges of high complexity. In South Africa, rapid and sustainable development is needed to address high levels of poverty and unemployment but this development has to take place in the context of an environment that is already severely impacted by human activities. Sound and relevant scientific input and advice, covering the full scope of each challenge, is essential for effective decisions and actions to address the needs. South Africa has the benefit of strong scientific capacity but the country’s National Development Plan reported that national research priorities were not always consistent with South Africa’s needs. We investigate the validity of that conclusion in the coastal and marine sciences by examining presentations made at the 2017 South African Marine Science Symposium on the theme of ‘Unlocking the ocean’s economic potential whilst maintaining social and ecological resilience’. Despite the theme, only 21% of the presentations were judged to be actionable and directly relevant to societal needs, as defined by the criteria used. Less than 7% were evaluated as being interdisciplinary within the natural sciences and approximately 10% were found to include both natural and human sciences. Poor representation by the human sciences was also noteworthy. This preliminary assessment highlights the need for an urgent review of the disciplinary representation and approaches in marine and coastal science in South Africa in the context of the priority practical needs of the country now and into the future.
- Full Text:
- Date Issued: 2019
Sectioned or whole otoliths? A global review of hard structure preparation techniques used in ageing sparid fishes
- Winkler, Alexander C, Duncan, Murray I, Farthing, Matthew W, Potts, Warren M
- Authors: Winkler, Alexander C , Duncan, Murray I , Farthing, Matthew W , Potts, Warren M
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/126733 , vital:35917 , https://doi.10.1007/s11160-019-09571-1
- Description: While otoliths are considered the most reliable structure to accurately age fish, a variety of otolith preparation techniques are available, which have consequences on the otolith’s optical properties and therefore interpretation of growth bands. Recently, numerous studies from a variety of authors have criticised the use of whole otoliths in ageing sparids with sectioned otoliths subsequently acknowledged as the most reliable preparation technique. Despite this criticism; ageing data is still being generated from whole otoliths and other unreliable structures such as scales. In an attempt to understand the severity of this issue we conducted a global literature review of otolith preparation protocols used for sparids. We identified global spatial inconsistencies in otolith preparation techniques with some regions predominately using methods other than sectioned otoliths to age sparids. The review highlights the need for a standardisation of otolith preparation methods and a move towards the use of sectioned otoliths, or at least valid support where alternative structures or preparation techniques are used. Given that large numbers of studies have been conducted on whole otoliths in certain regions, it may be necessary to revaluate the existing growth parameters to ensure that accurate information is incorporated into management structures.
- Full Text:
- Date Issued: 2019
- Authors: Winkler, Alexander C , Duncan, Murray I , Farthing, Matthew W , Potts, Warren M
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/126733 , vital:35917 , https://doi.10.1007/s11160-019-09571-1
- Description: While otoliths are considered the most reliable structure to accurately age fish, a variety of otolith preparation techniques are available, which have consequences on the otolith’s optical properties and therefore interpretation of growth bands. Recently, numerous studies from a variety of authors have criticised the use of whole otoliths in ageing sparids with sectioned otoliths subsequently acknowledged as the most reliable preparation technique. Despite this criticism; ageing data is still being generated from whole otoliths and other unreliable structures such as scales. In an attempt to understand the severity of this issue we conducted a global literature review of otolith preparation protocols used for sparids. We identified global spatial inconsistencies in otolith preparation techniques with some regions predominately using methods other than sectioned otoliths to age sparids. The review highlights the need for a standardisation of otolith preparation methods and a move towards the use of sectioned otoliths, or at least valid support where alternative structures or preparation techniques are used. Given that large numbers of studies have been conducted on whole otoliths in certain regions, it may be necessary to revaluate the existing growth parameters to ensure that accurate information is incorporated into management structures.
- Full Text:
- Date Issued: 2019
Semi-synthesis and evaluation of sargahydroquinoic acid derivatives as potential antimalarial agents:
- Munedzimwe, Tatenda C, van Zyl, Rovyn L, Heslop, Donovan C, Edkins, Adrienne L, Beukes, Denzil R
- Authors: Munedzimwe, Tatenda C , van Zyl, Rovyn L , Heslop, Donovan C , Edkins, Adrienne L , Beukes, Denzil R
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/163456 , vital:41040 , DOI: 10.3390/medicines6020047
- Description: Malaria continues to present a major health problem, especially in developing countries. The development of new antimalarial drugs to counter drug resistance and ensure a steady supply of new treatment options is therefore an important area of research. Meroditerpenes have previously been shown to exhibit antiplasmodial activity against a chloroquinone sensitive strain of Plasmodium falciparum (D10). In this study we explored the antiplasmodial activity of several semi-synthetic analogs of sargahydroquinoic acid.
- Full Text:
- Date Issued: 2019
- Authors: Munedzimwe, Tatenda C , van Zyl, Rovyn L , Heslop, Donovan C , Edkins, Adrienne L , Beukes, Denzil R
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/163456 , vital:41040 , DOI: 10.3390/medicines6020047
- Description: Malaria continues to present a major health problem, especially in developing countries. The development of new antimalarial drugs to counter drug resistance and ensure a steady supply of new treatment options is therefore an important area of research. Meroditerpenes have previously been shown to exhibit antiplasmodial activity against a chloroquinone sensitive strain of Plasmodium falciparum (D10). In this study we explored the antiplasmodial activity of several semi-synthetic analogs of sargahydroquinoic acid.
- Full Text:
- Date Issued: 2019
Short term stability testing of efavirenz-loaded solid lipid nanoparticle (SLN) and nanostructured lipid carrier (NLC) dispersions
- Makoni, Pedzisai A, Kasongo, Kasongo W, Walker, Roderick B
- Authors: Makoni, Pedzisai A , Kasongo, Kasongo W , Walker, Roderick B
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/183492 , vital:44000 , xlink:href="https://doi.org/10.3390/pharmaceutics11080397"
- Description: The short term stability of efavirenz-loaded solid lipid nanoparticle and nanostructured lipid carrier dispersions was investigated. Hot High Pressure Homogenization with the capability for scale up production was successfully used to manufacture the nanocarriers without the use of toxic organic solvents for the first time. Glyceryl monostearate and Transcutol® HP were used as the solid and liquid lipids. Tween® 80 was used to stabilize the lipid nanocarriers. A Box-Behnken Design was used to identify the optimum operating and production conditions viz., 1100 bar for 3 cycles for the solid lipid nanoparticles and 1500 bar for 5 cycles for nanostructured lipid carriers. The optimized nanocarriers were predicted to exhibit 10% efavirenz loading with 3% and 4% Tween® 80 for solid lipid nanoparticles and nanostructured lipid carriers, respectively. Characterization of the optimized solid lipid nanoparticle and nanostructured lipid carrier formulations in relation to shape, surface morphology, polymorphism, crystallinity and compatibility revealed stable formulations with particle sizes in the nanometer range had been produced. The nanocarriers had excellent efavirenz loading with the encapsulation efficiency >90%. The optimized nanocarriers exhibited biphasic in vitro release patterns with an initial burst release during the initial 0–3 h followed by sustained release over a 24 h period The colloidal systems showed excellent stability in terms of Zeta potential, particle size, polydispersity index and encapsulation efficiency when stored for 8 weeks at 25 °C/60% RH in comparison to when stored at 40 °C/75% RH. The formulations manufactured using the optimized conditions and composition proved to be physically stable as aqueous dispersions.
- Full Text:
- Date Issued: 2019
- Authors: Makoni, Pedzisai A , Kasongo, Kasongo W , Walker, Roderick B
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/183492 , vital:44000 , xlink:href="https://doi.org/10.3390/pharmaceutics11080397"
- Description: The short term stability of efavirenz-loaded solid lipid nanoparticle and nanostructured lipid carrier dispersions was investigated. Hot High Pressure Homogenization with the capability for scale up production was successfully used to manufacture the nanocarriers without the use of toxic organic solvents for the first time. Glyceryl monostearate and Transcutol® HP were used as the solid and liquid lipids. Tween® 80 was used to stabilize the lipid nanocarriers. A Box-Behnken Design was used to identify the optimum operating and production conditions viz., 1100 bar for 3 cycles for the solid lipid nanoparticles and 1500 bar for 5 cycles for nanostructured lipid carriers. The optimized nanocarriers were predicted to exhibit 10% efavirenz loading with 3% and 4% Tween® 80 for solid lipid nanoparticles and nanostructured lipid carriers, respectively. Characterization of the optimized solid lipid nanoparticle and nanostructured lipid carrier formulations in relation to shape, surface morphology, polymorphism, crystallinity and compatibility revealed stable formulations with particle sizes in the nanometer range had been produced. The nanocarriers had excellent efavirenz loading with the encapsulation efficiency >90%. The optimized nanocarriers exhibited biphasic in vitro release patterns with an initial burst release during the initial 0–3 h followed by sustained release over a 24 h period The colloidal systems showed excellent stability in terms of Zeta potential, particle size, polydispersity index and encapsulation efficiency when stored for 8 weeks at 25 °C/60% RH in comparison to when stored at 40 °C/75% RH. The formulations manufactured using the optimized conditions and composition proved to be physically stable as aqueous dispersions.
- Full Text:
- Date Issued: 2019
Should I stay or should I go?: Intra-population variability in movement behaviour of wide-ranging and resident coastal fishes
- Maggs, Jade Q, Cowley, Paul D, Porter, S N, Childs, Amber-Robyn
- Authors: Maggs, Jade Q , Cowley, Paul D , Porter, S N , Childs, Amber-Robyn
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/158290 , vital:40170 , https://doi.org/10.3354/meps12953
- Description: Life-cycle diversity is the existence of alternative strategies among coexisting individuals within the same population and is an important factor in the structuring and connectivity of fish stocks. Mark-recapture data, collected along the coastline of southern Africa from 1984-2015, were used to investigate the occurrence of different movement behaviours (resident vs. wide-ranging) in 5 fishery species with contrasting life histories. A total of 88245 individuals was tagged, with recapture rates ranging from 4-27% for the 5 species. Individuals were considered resident if recaptured within 0-5 km of the release site after 365 d at liberty or wide-ranging if recaptured more than 50 km from the release site within 365 d.
- Full Text:
- Date Issued: 2019
- Authors: Maggs, Jade Q , Cowley, Paul D , Porter, S N , Childs, Amber-Robyn
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/158290 , vital:40170 , https://doi.org/10.3354/meps12953
- Description: Life-cycle diversity is the existence of alternative strategies among coexisting individuals within the same population and is an important factor in the structuring and connectivity of fish stocks. Mark-recapture data, collected along the coastline of southern Africa from 1984-2015, were used to investigate the occurrence of different movement behaviours (resident vs. wide-ranging) in 5 fishery species with contrasting life histories. A total of 88245 individuals was tagged, with recapture rates ranging from 4-27% for the 5 species. Individuals were considered resident if recaptured within 0-5 km of the release site after 365 d at liberty or wide-ranging if recaptured more than 50 km from the release site within 365 d.
- Full Text:
- Date Issued: 2019
Simulated global increases in atmospheric CO2 alter the tissue composition, but not the growth of some submerged aquatic plant bicarbonate users growing in DIC rich waters
- Hussner, Andreas, Smith, Rosali, Mettler-Altmann, Tabea, Hill, Martin P, Coetzee, Julie A
- Authors: Hussner, Andreas , Smith, Rosali , Mettler-Altmann, Tabea , Hill, Martin P , Coetzee, Julie A
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/419388 , vital:71640 , xlink:href="https://doi.org/10.1016/j.aquabot.2018.11.009"
- Description: Current global change scenarios predict an increase in atmospheric CO2 from the current 380 ppm to a value ranging from 540 ppm to 960 ppm by the year 2100. The effects of three air CO2 levels (400, 600 and 800 ppm) on five submerged aquatic plants that utilize HCO3− were studied, using the elevated CO2 Open Top Chamber facility at Rhodes University (Grahamstown, South Africa). Plants grew in water with two different initial dissolved inorganic carbon (DIC) concentrations of 1.5 and 3.0 mM. Overall, the growth rates and biomass allocation to roots were not affected by the initial DIC and air CO2, even though differences between the species were found. Furthermore, no overall effects were found on net photosynthesis, chlorophyll and starch content, even though significant effects of CO2 and DIC were observed in some species. In contrast, with increasing DIC and air CO2 a significant global decline in leaf nitrogen content linked with an increased C:N molar ratio was observed. The results indicate that submerged aquatic HCO3− users will be less affected by atmospheric CO2 increases when growing in DIC rich waters, in comparison to obligate CO2 users growing under CO2 limiting conditions as documented in previous studies. However, the changes found in plant nitrogen illustrate that atmospheric CO2 increases will affect nitrogen absorption by submerged plants, with subsequent ecosystem level effects.
- Full Text:
- Date Issued: 2019
- Authors: Hussner, Andreas , Smith, Rosali , Mettler-Altmann, Tabea , Hill, Martin P , Coetzee, Julie A
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/419388 , vital:71640 , xlink:href="https://doi.org/10.1016/j.aquabot.2018.11.009"
- Description: Current global change scenarios predict an increase in atmospheric CO2 from the current 380 ppm to a value ranging from 540 ppm to 960 ppm by the year 2100. The effects of three air CO2 levels (400, 600 and 800 ppm) on five submerged aquatic plants that utilize HCO3− were studied, using the elevated CO2 Open Top Chamber facility at Rhodes University (Grahamstown, South Africa). Plants grew in water with two different initial dissolved inorganic carbon (DIC) concentrations of 1.5 and 3.0 mM. Overall, the growth rates and biomass allocation to roots were not affected by the initial DIC and air CO2, even though differences between the species were found. Furthermore, no overall effects were found on net photosynthesis, chlorophyll and starch content, even though significant effects of CO2 and DIC were observed in some species. In contrast, with increasing DIC and air CO2 a significant global decline in leaf nitrogen content linked with an increased C:N molar ratio was observed. The results indicate that submerged aquatic HCO3− users will be less affected by atmospheric CO2 increases when growing in DIC rich waters, in comparison to obligate CO2 users growing under CO2 limiting conditions as documented in previous studies. However, the changes found in plant nitrogen illustrate that atmospheric CO2 increases will affect nitrogen absorption by submerged plants, with subsequent ecosystem level effects.
- Full Text:
- Date Issued: 2019
South African Abietane Diterpenoids and their analogs as potential antimalarials: novel insights from hybrid computational approaches
- Musyoka, Thommas M, Tastan Bishop, Özlem
- Authors: Musyoka, Thommas M , Tastan Bishop, Özlem
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/162665 , vital:40971 , https://doi.org/10.3390/molecules24224036
- Description: The hemoglobin degradation process in Plasmodium parasites is vital for nutrient acquisition required for their growth and proliferation. In P. falciparum, falcipains (FP-2 and FP-3) are the major hemoglobinases, and remain attractive antimalarial drug targets. Other Plasmodium species also possess highly homologous proteins to FP-2 and FP-3. Although several inhibitors have been designed against these proteins, none has been commercialized due to associated toxicity on human cathepsins (Cat-K, Cat-L and Cat-S). Despite the two enzyme groups sharing a common structural fold and catalytic mechanism, distinct active site variations have been identified, and can be exploited for drug development. Here, we utilize in silico approaches to screen 628 compounds from the South African natural sources to identify potential hits that can selectively inhibit the plasmodial proteases.
- Full Text:
- Date Issued: 2019
- Authors: Musyoka, Thommas M , Tastan Bishop, Özlem
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/162665 , vital:40971 , https://doi.org/10.3390/molecules24224036
- Description: The hemoglobin degradation process in Plasmodium parasites is vital for nutrient acquisition required for their growth and proliferation. In P. falciparum, falcipains (FP-2 and FP-3) are the major hemoglobinases, and remain attractive antimalarial drug targets. Other Plasmodium species also possess highly homologous proteins to FP-2 and FP-3. Although several inhibitors have been designed against these proteins, none has been commercialized due to associated toxicity on human cathepsins (Cat-K, Cat-L and Cat-S). Despite the two enzyme groups sharing a common structural fold and catalytic mechanism, distinct active site variations have been identified, and can be exploited for drug development. Here, we utilize in silico approaches to screen 628 compounds from the South African natural sources to identify potential hits that can selectively inhibit the plasmodial proteases.
- Full Text:
- Date Issued: 2019
Spatial and Seasonal Distribution of Forensically Important Blow Flies (Diptera: Calliphoridae) in Makhanda, Eastern Cape, South Africa:
- Williams, Kirstin A, Villet, Martin H
- Authors: Williams, Kirstin A , Villet, Martin H
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/140716 , vital:37912 , DOI: 10.1093/jme/tjz056
- Description: The seasonal activity of adults of eight forensically important blow fly species [Calliphora croceipalpis (Diptera: Calliphoridae), Jaennicke, Lucilia sericata (Meigen) (Diptera: Calliphoridae), L. cuprina (Wiedemann) (Diptera: Calliphoridae), Chrysomya chloropyga (Wiedemann) (Diptera: Calliphoridae), Ch. albiceps (Wiedemann) (Diptera: Calliphoridae), Ch. marginalis (Wiedemann) (Diptera: Calliphoridae), Ch. putoria (Wiedemann) (Diptera: Calliphoridae), Ch. megacephala (Fabricius) (Diptera: Calliphoridae)] was quantified from collections in Makhanda, South Africa. Flies were collected in traps baited with chicken liver and placed in the field at eight locations for four consecutive days each fortnight for 14 mo. The seasonal distribution of each species compared well to published seasonal distributions of these blow flies elsewhere in South Africa, with evidence of year-to-year variation within seasons that might be explained by weather. This information is important for determining when and where certain species are likely to occur and will be of use in forensic investigations and myiasis management plans.
- Full Text:
- Date Issued: 2019
- Authors: Williams, Kirstin A , Villet, Martin H
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/140716 , vital:37912 , DOI: 10.1093/jme/tjz056
- Description: The seasonal activity of adults of eight forensically important blow fly species [Calliphora croceipalpis (Diptera: Calliphoridae), Jaennicke, Lucilia sericata (Meigen) (Diptera: Calliphoridae), L. cuprina (Wiedemann) (Diptera: Calliphoridae), Chrysomya chloropyga (Wiedemann) (Diptera: Calliphoridae), Ch. albiceps (Wiedemann) (Diptera: Calliphoridae), Ch. marginalis (Wiedemann) (Diptera: Calliphoridae), Ch. putoria (Wiedemann) (Diptera: Calliphoridae), Ch. megacephala (Fabricius) (Diptera: Calliphoridae)] was quantified from collections in Makhanda, South Africa. Flies were collected in traps baited with chicken liver and placed in the field at eight locations for four consecutive days each fortnight for 14 mo. The seasonal distribution of each species compared well to published seasonal distributions of these blow flies elsewhere in South Africa, with evidence of year-to-year variation within seasons that might be explained by weather. This information is important for determining when and where certain species are likely to occur and will be of use in forensic investigations and myiasis management plans.
- Full Text:
- Date Issued: 2019
Speaking to power through newspaper editorials in Zimbabwe:
- Nyaungwa, Mathew, Garman, Anthea
- Authors: Nyaungwa, Mathew , Garman, Anthea
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/158438 , vital:40186 , https://0-doi.org.wam.seals.ac.za/10.1386/jams.11.1.51_1
- Description: This article seeks to provide an insight into the complex role that editorials – a newspaper’s institutional voice – play in highly polarised political contexts. It focuses on how the editorials of two Zimbabwean daily newspapers – The Herald, a progovernment newspaper, and NewsDay, a perceived pro-opposition newspaper – spoke to those in power at a time of transition from a government of national unity to majoritarian rule in 2013. The study also sets out to understand how both the newspapers’ editorials over this time responded to a contested political domain. Qualitative content analysis, rhetorical analysis and in-depth interviews were used to consider the tactics employed in the editorials to question and challenge the decisions and behaviours of those in positions of authority. The research findings contradict the common view in Zimbabwe that the privately–owned media blindly support the opposition while the state-owned media do the same with ZANU-PF. The findings show that in the period in question both newspapers exploited the editorial as a space to urge politicians to think of the national common good.
- Full Text:
- Date Issued: 2019
- Authors: Nyaungwa, Mathew , Garman, Anthea
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/158438 , vital:40186 , https://0-doi.org.wam.seals.ac.za/10.1386/jams.11.1.51_1
- Description: This article seeks to provide an insight into the complex role that editorials – a newspaper’s institutional voice – play in highly polarised political contexts. It focuses on how the editorials of two Zimbabwean daily newspapers – The Herald, a progovernment newspaper, and NewsDay, a perceived pro-opposition newspaper – spoke to those in power at a time of transition from a government of national unity to majoritarian rule in 2013. The study also sets out to understand how both the newspapers’ editorials over this time responded to a contested political domain. Qualitative content analysis, rhetorical analysis and in-depth interviews were used to consider the tactics employed in the editorials to question and challenge the decisions and behaviours of those in positions of authority. The research findings contradict the common view in Zimbabwe that the privately–owned media blindly support the opposition while the state-owned media do the same with ZANU-PF. The findings show that in the period in question both newspapers exploited the editorial as a space to urge politicians to think of the national common good.
- Full Text:
- Date Issued: 2019
Species succession and the development of a lacustrine fish community in an ephemeral lake
- Peel, Richard A, Hill, Jaclyn M, Taylor, Geraldine C, Tweddle, Denis, Weyl, Olaf L F
- Authors: Peel, Richard A , Hill, Jaclyn M , Taylor, Geraldine C , Tweddle, Denis , Weyl, Olaf L F
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/444704 , vital:74261 , https://doi.org/10.1111/jfb.14081
- Description: Here, we present a gillnet survey of Lake Liambezi a 370 km2 shallow ephemeral floodplain lake situated in north‐eastern Namibia, which is fed irregularly by the upper Zambezi and Kwando Rivers during years of high flooding. The lake dried up in 1985 and, with the exception of sporadic minor annual inundation events, remained dry until 2007. We describe the temporal succession of fish species over an 8 year period from initial inundation 2007 to maturation in 2014. The succession of the fish community did not follow the typical pattern of opportunistic strategists during colonisation, to periodic strategists that are eventually succeeded by equilibrium strategists. Instead, the evolution of the fish community was characterised by three distinct phases. The first phase involved the inundation and colonisation of the lake in 2007, followed by its decline until the floods that filled the lake in 2009. During this phase the lake was colonised by fishes from the adjacent upper Zambezi and Chobe River floodplains.
- Full Text:
- Date Issued: 2019
- Authors: Peel, Richard A , Hill, Jaclyn M , Taylor, Geraldine C , Tweddle, Denis , Weyl, Olaf L F
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/444704 , vital:74261 , https://doi.org/10.1111/jfb.14081
- Description: Here, we present a gillnet survey of Lake Liambezi a 370 km2 shallow ephemeral floodplain lake situated in north‐eastern Namibia, which is fed irregularly by the upper Zambezi and Kwando Rivers during years of high flooding. The lake dried up in 1985 and, with the exception of sporadic minor annual inundation events, remained dry until 2007. We describe the temporal succession of fish species over an 8 year period from initial inundation 2007 to maturation in 2014. The succession of the fish community did not follow the typical pattern of opportunistic strategists during colonisation, to periodic strategists that are eventually succeeded by equilibrium strategists. Instead, the evolution of the fish community was characterised by three distinct phases. The first phase involved the inundation and colonisation of the lake in 2007, followed by its decline until the floods that filled the lake in 2009. During this phase the lake was colonised by fishes from the adjacent upper Zambezi and Chobe River floodplains.
- Full Text:
- Date Issued: 2019
Spectroscopic and nonlinear optical properties of alkyl thio substituted binuclear phthalocyanines
- Makinde, Zainab O, Louzada, Marcel S, Britton, Jonathan, Nyokong, Tebello, Khene, Samson M
- Authors: Makinde, Zainab O , Louzada, Marcel S , Britton, Jonathan , Nyokong, Tebello , Khene, Samson M
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/187485 , vital:44661 , xlink:href="https://doi.org/10.1016/j.dyepig.2018.10.022"
- Description: This work presents the spectroscopic and nonlinear optical properties of metal free binuclear and monomeric 4- (pentylthio)phthalocyanine and cobalt 4,5-(bipentylthio)phthalocyanine. Second order nonlinear absorption coefficient (β) values for the complexes were determined and compared.
- Full Text:
- Date Issued: 2019
- Authors: Makinde, Zainab O , Louzada, Marcel S , Britton, Jonathan , Nyokong, Tebello , Khene, Samson M
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/187485 , vital:44661 , xlink:href="https://doi.org/10.1016/j.dyepig.2018.10.022"
- Description: This work presents the spectroscopic and nonlinear optical properties of metal free binuclear and monomeric 4- (pentylthio)phthalocyanine and cobalt 4,5-(bipentylthio)phthalocyanine. Second order nonlinear absorption coefficient (β) values for the complexes were determined and compared.
- Full Text:
- Date Issued: 2019
Spectroscopic characterization and photodynamic antimicrobial chemotherapy of phthalocyanine-silver triangular nanoprism conjugates when supported on asymmetric polymer membranes
- Mafukidze, Donovan M, Sindelo, Azole, Nyokong, Tebello
- Authors: Mafukidze, Donovan M , Sindelo, Azole , Nyokong, Tebello
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/186927 , vital:44548 , xlink:href="https://doi.org/10.1016/j.saa.2019.04.054"
- Description: Silver triangular nanoprisms were synthesized and conjugated to zinc (ZnPc) and indium (InPc) phthalocyanines prior to embedding in asymmetric membranes. Conjugation of nanoparticles increased triplet state and singlet oxygen quantum yields of the phthalocyanines as well as enhancing photodynamic antimicrobial chemotherapy (PACT) activity against bacteria (S. aureus). The ZnPc derivative showed higher PACT activity when compared to the InPc, possibly due to degradation of the latter in aqueous media.
- Full Text:
- Date Issued: 2019
- Authors: Mafukidze, Donovan M , Sindelo, Azole , Nyokong, Tebello
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/186927 , vital:44548 , xlink:href="https://doi.org/10.1016/j.saa.2019.04.054"
- Description: Silver triangular nanoprisms were synthesized and conjugated to zinc (ZnPc) and indium (InPc) phthalocyanines prior to embedding in asymmetric membranes. Conjugation of nanoparticles increased triplet state and singlet oxygen quantum yields of the phthalocyanines as well as enhancing photodynamic antimicrobial chemotherapy (PACT) activity against bacteria (S. aureus). The ZnPc derivative showed higher PACT activity when compared to the InPc, possibly due to degradation of the latter in aqueous media.
- Full Text:
- Date Issued: 2019
Stability indicating HPLC-ECD method for the analysis of clarithromycin in pharmaceutical dosage forms: Method scaling versus re-validation.
- Makoni, Pedzisai A, Chikukwa, Mellisa T R, Khamanga, Sandile M, Walker, Roderick B
- Authors: Makoni, Pedzisai A , Chikukwa, Mellisa T R , Khamanga, Sandile M , Walker, Roderick B
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/183387 , vital:43984 , xlink:href="https://doi.org/10.3390/scipharm87040031"
- Description: An isocratic high-performance liquid chromatographic method using electrochemical detection (HPLC-ECD) for the quantitation of clarithromycin (CLA) was developed using Response Surface Methodology (RSM) based on a Central Composite Design (CCD). The method was validated using International Conference on Harmonization (ICH) guidelines with an analytical run time of 20 min. Method re-validation following a change in analytical column was successful in reducing the analytical run time to 13 min, decreasing solvent consumption thus facilitating environmental and financial sustainability. The applicability of using the United States Pharmacopeia (USP) method scaling approach in place of method re-validation using a column with a different L–designation to the original analytical column, was investigated. The scaled method met all USP system suitability requirements for resolution, tailing factor and % relative standard deviation (RSD). The re-validated and scaled method was successfully used to resolve CLA from manufacturing excipients in commercially available dosage forms. Although USP method scaling is only permitted for columns within the same L-designation, these data suggest that it may also be applicable to columns of different designation.
- Full Text:
- Date Issued: 2019
- Authors: Makoni, Pedzisai A , Chikukwa, Mellisa T R , Khamanga, Sandile M , Walker, Roderick B
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/183387 , vital:43984 , xlink:href="https://doi.org/10.3390/scipharm87040031"
- Description: An isocratic high-performance liquid chromatographic method using electrochemical detection (HPLC-ECD) for the quantitation of clarithromycin (CLA) was developed using Response Surface Methodology (RSM) based on a Central Composite Design (CCD). The method was validated using International Conference on Harmonization (ICH) guidelines with an analytical run time of 20 min. Method re-validation following a change in analytical column was successful in reducing the analytical run time to 13 min, decreasing solvent consumption thus facilitating environmental and financial sustainability. The applicability of using the United States Pharmacopeia (USP) method scaling approach in place of method re-validation using a column with a different L–designation to the original analytical column, was investigated. The scaled method met all USP system suitability requirements for resolution, tailing factor and % relative standard deviation (RSD). The re-validated and scaled method was successfully used to resolve CLA from manufacturing excipients in commercially available dosage forms. Although USP method scaling is only permitted for columns within the same L-designation, these data suggest that it may also be applicable to columns of different designation.
- Full Text:
- Date Issued: 2019
Strength and Sprint Time Changes in Response to Repeated Shuttles Between the Wickets During Batting in Cricket
- Christie, Candice J, Sheppard, Bronwyn J, Goble, David, Pote, Lee, Noakes, Timothy
- Authors: Christie, Candice J , Sheppard, Bronwyn J , Goble, David , Pote, Lee , Noakes, Timothy
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/127133 , vital:35959 , https://doi.org/10.1519/jsc.0000000000002585
- Description: Christie CJ, Sheppard B, Goble D, Pote L, and Noakes TD. Strength and sprint time changes in response to repeated shuttles between the wickets during batting in cricket. J Strength Cond Res XX(X): 000–000, 2018—No studies have investigated the impact of repeated sprints between the wickets on lower-limb strength and sprint performance. Therefore, the purpose of this study was to assess changes in knee extensor (EXT) and flexor (FLEX) strength after repeated sprints between the wickets and to relate these to changes in sprint times. Twenty batters completed 2 conditions: onewas high-volume running (HVR-twelve sprints per over) and the other, moderate-volume running (MVR-6 sprints per over) between the wickets (42 deliveries in both). Peak isokinetic torque was measured before and after each condition and sprint times were recorded. Eccentric and concentric peak torque decreased significantly (p , 0.05) at 1.05 rad˙s ̄1 for knee EXT in both conditions. There was an 18% (HVR) and 10% (MVR) decline in concentric and eccentric knee EXT peak torque. Peak FLEX torques were significantly (p , 0.05) reduced after HVR (16.7%) but not after the MVR condition (8%). There were similar declines in eccentric FLEX peak torque. Sprint times increased significantly (p , 0.05) during the HVR condition but not in the MVR condition; sprint times in the HVR condition were compromised as early as the third over. We conclude that a high volume of runs significantly reduces muscle function in the lower limbs, partly explaining the impairment in sprint performance. However, because batters slowed as early as the third over in the HVR condition, there may be some form of strategy used in anticipation of a higher overall workload. More middle wicket practices, focusing on repeat shuttle sprints while batting, should be included in the coaching program.
- Full Text:
- Date Issued: 2019
- Authors: Christie, Candice J , Sheppard, Bronwyn J , Goble, David , Pote, Lee , Noakes, Timothy
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/127133 , vital:35959 , https://doi.org/10.1519/jsc.0000000000002585
- Description: Christie CJ, Sheppard B, Goble D, Pote L, and Noakes TD. Strength and sprint time changes in response to repeated shuttles between the wickets during batting in cricket. J Strength Cond Res XX(X): 000–000, 2018—No studies have investigated the impact of repeated sprints between the wickets on lower-limb strength and sprint performance. Therefore, the purpose of this study was to assess changes in knee extensor (EXT) and flexor (FLEX) strength after repeated sprints between the wickets and to relate these to changes in sprint times. Twenty batters completed 2 conditions: onewas high-volume running (HVR-twelve sprints per over) and the other, moderate-volume running (MVR-6 sprints per over) between the wickets (42 deliveries in both). Peak isokinetic torque was measured before and after each condition and sprint times were recorded. Eccentric and concentric peak torque decreased significantly (p , 0.05) at 1.05 rad˙s ̄1 for knee EXT in both conditions. There was an 18% (HVR) and 10% (MVR) decline in concentric and eccentric knee EXT peak torque. Peak FLEX torques were significantly (p , 0.05) reduced after HVR (16.7%) but not after the MVR condition (8%). There were similar declines in eccentric FLEX peak torque. Sprint times increased significantly (p , 0.05) during the HVR condition but not in the MVR condition; sprint times in the HVR condition were compromised as early as the third over. We conclude that a high volume of runs significantly reduces muscle function in the lower limbs, partly explaining the impairment in sprint performance. However, because batters slowed as early as the third over in the HVR condition, there may be some form of strategy used in anticipation of a higher overall workload. More middle wicket practices, focusing on repeat shuttle sprints while batting, should be included in the coaching program.
- Full Text:
- Date Issued: 2019